Analysis of monoclonal antibody sequence and post-translational modifications by time-controlled proteolysis and tandem mass spectrometry

Molecular and Cellular Proteomics

Volumn 15, Issue 4, 2016, Pages 1479-1488

  Zhang, Lichao ^a,d   English, A Michelle ^a   Bai, Dina L ^a   Ugrin, Scott A ^a   Shabanowitz, Jeffrey ^a   Ross, Mark M ^a   Hunt, Donald F ^a,b,c   Wang, Wei Han ^a,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOMYOGLOBIN; BIOLOGICAL MARKER; METHIONINE; MONOCLONAL ANTIBODY; PEPTIDE; PROTEINASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ASPERGILLUS SAITOI; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISULFIDE BOND; ELECTRON TRANSPORT; FLOW RATE; GLYCOSYLATION; HORSE; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTON TRANSPORT; REACTOR; SEQUENCE ANALYSIS; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; PROCEDURES; PROTEIN CONFORMATION; TIME FACTOR;

ANIMALS; ANTIBODIES, MONOCLONAL; MICE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; SEQUENCE ANALYSIS, PROTEIN; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 84995459702     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.O115.056721     Document Type: Article

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