Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy

Oncotarget

Volumn 7, Issue 44, 2016, Pages 71696-71702

  Hiroshima, Yukihiko ^a,b,c   Maawy, Ali ^b   Zhang, Yong ^a   Zhang, Nan ^a   Murakami, Takashi ^c   Chishima, Takashi ^c   Tanaka, Kuniya ^c   Ichikawa, Yasushi ^c   Bouvet, Michael ^b   Endo, Itaru ^c   Hoffman, Robert M ^a,b  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cervical cancer; Nude mouse; Patient derived orthotopic xenograft; PDOX; Primary tumor

Indexed keywords

CARBOPLATIN; ENTINOSTAT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; TRASTUZUMAB; BENZAMIDE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER MODEL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; METASTASIS INHIBITION; MONOTHERAPY; MOUSE; MOUSE MODEL; NONHUMAN; NUDE MOUSE; PERITONEUM METASTASIS; PERSONALIZED MEDICINE; UTERINE CERVIX CARCINOMA; ANIMAL; DISEASE MODEL; DRUG SCREENING; HUMAN; METASTASIS; PATHOLOGY; UTERINE CERVIX TUMOR;

ANIMALS; BENZAMIDES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MICE; NEOPLASM METASTASIS; PRECISION MEDICINE; PYRIDINES; UTERINE CERVICAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84995388219     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.12322     Document Type: Article

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