-
1
-
-
33746900560
-
Origin of cancer cells
-
13335077,; PMID:,; CrossRef
-
Warburg, O. Origin of cancer cells. Oncologia 1956; 9:75-83; PMID:13335077; CrossRef
-
(1956)
Oncologia
, vol.9
, pp. 75-83
-
-
Warburg, O.1
-
2
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
18337823,; PMID:,; CrossRef
-
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, Cantley LC. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 2008; 452:230-3; PMID:18337823; CrossRef
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
3
-
-
76649102764
-
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
-
20133837,; PMID:,; CrossRef
-
Clower CV, Chatterjee D, Wang Z, Cantley LC, Vander Heiden MG, Krainer AR. The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proc Natl Acad Sci U S A 2010; 107:1894-9; PMID:20133837; CrossRef
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1894-1899
-
-
Clower, C.V.1
Chatterjee, D.2
Wang, Z.3
Cantley, L.C.4
Vander Heiden, M.G.5
Krainer, A.R.6
-
4
-
-
84866842363
-
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
-
22922757,; PMID:,; CrossRef
-
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, et al. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol 2012; 8:839-47; PMID:22922757; CrossRef
-
(2012)
Nat Chem Biol
, vol.8
, pp. 839-847
-
-
Anastasiou, D.1
Yu, Y.2
Israelsen, W.J.3
Jiang, J.K.4
Boxer, M.B.5
Hong, B.S.6
Tempel, W.7
Dimov, S.8
Shen, M.9
Jha, A.10
-
5
-
-
84908058792
-
Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis
-
25215489,; PMID:,; CrossRef
-
Wang YH, Israelsen WJ, Lee D, Yu VW, Jeanson NT, Clish CB, Cantley LC, Vander Heiden MG, Scadden DT. Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis. Cell 2014; 158:1309-23; PMID:25215489; CrossRef
-
(2014)
Cell
, vol.158
, pp. 1309-1323
-
-
Wang, Y.H.1
Israelsen, W.J.2
Lee, D.3
Yu, V.W.4
Jeanson, N.T.5
Clish, C.B.6
Cantley, L.C.7
Vander Heiden, M.G.8
Scadden, D.T.9
-
6
-
-
76649126249
-
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
-
20133848,; PMID:,; CrossRef
-
Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A 2010; 107:2037-42; PMID:20133848; CrossRef
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2037-2042
-
-
Le, A.1
Cooper, C.R.2
Gouw, A.M.3
Dinavahi, R.4
Maitra, A.5
Deck, L.M.6
Royer, R.E.7
Vander Jagt, D.L.8
Semenza, G.L.9
Dang, C.V.10
-
7
-
-
0032535764
-
Lineage involvement of stem cells bearing the philadelphia chromosome in chronic myeloid leukemia in the chronic phase as shown by a combination of fluorescence-activated cell sorting and fluorescence in situ hybridization
-
9845542,; PMID
-
Takahashi N, Miura I, Saitoh K, Miura AB. Lineage involvement of stem cells bearing the philadelphia chromosome in chronic myeloid leukemia in the chronic phase as shown by a combination of fluorescence-activated cell sorting and fluorescence in situ hybridization. Blood 1998; 92:4758-63; PMID:9845542
-
(1998)
Blood
, vol.92
, pp. 4758-4763
-
-
Takahashi, N.1
Miura, I.2
Saitoh, K.3
Miura, A.B.4
-
8
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
16862118,; PMID:,; CrossRef
-
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006; 442:818-22; PMID:16862118; CrossRef
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
Stubbs, M.C.4
Wang, Y.5
Faber, J.6
Levine, J.E.7
Wang, J.8
Hahn, W.C.9
Gilliland, D.G.10
-
9
-
-
84900296103
-
Targeting lactate dehydrogenase–a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells
-
24726384,; PMID:,; CrossRef
-
Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, et al. Targeting lactate dehydrogenase–a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells. Cell Metab 2014; 19:795-809; PMID:24726384; CrossRef
-
(2014)
Cell Metab
, vol.19
, pp. 795-809
-
-
Xie, H.1
Hanai, J.2
Ren, J.G.3
Kats, L.4
Burgess, K.5
Bhargava, P.6
Signoretti, S.7
Billiard, J.8
Duffy, K.J.9
Grant, A.10
-
10
-
-
84885589840
-
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells
-
24120138,; PMID:,; CrossRef
-
Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, et al. PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell 2013; 155:397-409; PMID:24120138; CrossRef
-
(2013)
Cell
, vol.155
, pp. 397-409
-
-
Israelsen, W.J.1
Dayton, T.L.2
Davidson, S.M.3
Fiske, B.P.4
Hosios, A.M.5
Bellinger, G.6
Li, J.7
Yu, Y.8
Sasaki, M.9
Horner, J.W.10
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