메뉴 건너뛰기




Volumn 62, Issue 4, 2016, Pages 123-129

Icariin induces S-phase arrest and apoptosis in medulloblastoma cells

Author keywords

Apoptosis; Cell cycle; Icariin; Medulloblastoma

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 2; CYCLINE; HOE 33342; ICARIIN; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPIDIUM IODIDE; PROTEIN BCL 2; FLAVONOID;

EID: 84994840308     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.14715/cmb/2016.62.4.21     Document Type: Article
Times cited : (17)

References (26)
  • 1
    • 84925884802 scopus 로고    scopus 로고
    • Medulloblastoma: Recurrence and metastasis
    • Aref D, Croul S. Medulloblastoma: Recurrence and metastasis. CNS Oncol 2013; 2:377-385.
    • (2013) CNS Oncol , vol.2 , pp. 377-385
    • Aref, D.1    Croul, S.2
  • 3
    • 77957932118 scopus 로고    scopus 로고
    • Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway
    • Li S, Dong P, Wang J, Zhang J, Gu J, Wu X, et al. Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway. Cancer Lett 2010; 298:222-230.
    • (2010) Cancer Lett , vol.298 , pp. 222-230
    • Li, S.1    Dong, P.2    Wang, J.3    Zhang, J.4    Gu, J.5    Wu, X.6
  • 4
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton EJ, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000; 52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton, E.J.1    Kandaswami, C.2    Theoharides, T.C.3
  • 5
    • 34249781984 scopus 로고    scopus 로고
    • Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats
    • Pan Y, Kong LD, Li YC, Xia X, Kung HF, Jiang FX. Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats. Pharmacol Biochem Behav 2007; 87:130-140.
    • (2007) Pharmacol Biochem Behav , vol.87 , pp. 130-140
    • Pan, Y.1    Kong, L.D.2    Li, Y.C.3    Xia, X.4    Kung, H.F.5    Jiang, F.X.6
  • 6
    • 34249280557 scopus 로고    scopus 로고
    • Icariin enhances endothelial nitric-oxide synthase expression on human endothelial cells in vitro
    • Xu HB, Huang ZQ. Icariin enhances endothelial nitric-oxide synthase expression on human endothelial cells in vitro. Vascul Pharmacol 2007; 47:18-24.
    • (2007) Vascul Pharmacol , vol.47 , pp. 18-24
    • Xu, H.B.1    Huang, Z.Q.2
  • 7
    • 0029111787 scopus 로고
    • Immunoregulatory effects of the herba Epimediia glycoside icariin
    • He W, Sun H, Yang B, Zhang D, Kabelitz D. Immunoregulatory effects of the herba Epimediia glycoside icariin. Arzneimittelforschung 1995; 45: 910-913.
    • (1995) Arzneimittelforschung , vol.45 , pp. 910-913
    • He, W.1    Sun, H.2    Yang, B.3    Zhang, D.4    Kabelitz, D.5
  • 8
    • 84902381241 scopus 로고    scopus 로고
    • Icariinmediated inhibition of NF-kappaB activity enhances the in vitro and in vivo antitumour effect of 5-fluorouracil in colorectal cancer
    • Shi DB, Li XX, Zheng HT, Li DW, Cai GX, Peng JJ, et al. Icariinmediated inhibition of NF-kappaB activity enhances the in vitro and in vivo antitumour effect of 5-fluorouracil in colorectal cancer. Cell Biochem Biophys 2014;69:523-530.
    • (2014) Cell Biochem Biophys , vol.69 , pp. 523-530
    • Shi, D.B.1    Li, X.X.2    Zheng, H.T.3    Li, D.W.4    Cai, G.X.5    Peng, J.J.6
  • 9
    • 84893967474 scopus 로고    scopus 로고
    • Icariin synergizes with arsenic trioxide to suppress human hepatocellular carcinoma
    • Li W, Wang M, Wang L, Ji S, Zhang J, Zhang C. Icariin synergizes with arsenic trioxide to suppress human hepatocellular carcinoma. Cell Biochem Biophys 2014;68: 427-436.
    • (2014) Cell Biochem Biophys , vol.68 , pp. 427-436
    • Li, W.1    Wang, M.2    Wang, L.3    Ji, S.4    Zhang, J.5    Zhang, C.6
  • 10
    • 84873547035 scopus 로고    scopus 로고
    • Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-kappaB
    • Zhang DC, Liu JL, Ding YB, Xia JG, Chen GY. Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-kappaB. Acta Pharmacol Sin 2013;34:301-308.
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 301-308
    • Zhang, D.C.1    Liu, J.L.2    Ding, Y.B.3    Xia, J.G.4    Chen, G.Y.5
  • 11
    • 84890011075 scopus 로고    scopus 로고
    • Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model
    • Zeng L, Wang W, Rong XF, Zhong Y, Jia P, Zhou GQ, et al. Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model. Int Immunopharmacol 2014;18: 175-181.
    • (2014) Int Immunopharmacol , vol.18 , pp. 175-181
    • Zeng, L.1    Wang, W.2    Rong, X.F.3    Zhong, Y.4    Jia, P.5    Zhou, G.Q.6
  • 12
    • 79651470943 scopus 로고    scopus 로고
    • Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons
    • Liu B, Zhang H, Xu C, Yang G, Tao J, Huang J, et al. Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. Brain Res 2011;1375: 59-67.
    • (2011) Brain Res , vol.1375 , pp. 59-67
    • Liu, B.1    Zhang, H.2    Xu, C.3    Yang, G.4    Tao, J.5    Huang, J.6
  • 13
    • 77956920667 scopus 로고    scopus 로고
    • Icariin attenuates betaamyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells
    • Zeng KW, Ko H, Yang HO, Wang XM. Icariin attenuates betaamyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells. Neuropharmacology 2010;59: 542-550.
    • (2010) Neuropharmacology , vol.59 , pp. 542-550
    • Zeng, K.W.1    Ko, H.2    Yang, H.O.3    Wang, X.M.4
  • 14
    • 33845296134 scopus 로고    scopus 로고
    • Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells
    • Ning H, Xin ZC, Lin G, Banie L, Lue TF, Lin CS. Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells. Urology 2006;68:1350-1354.
    • (2006) Urology , vol.68 , pp. 1350-1354
    • Ning, H.1    Xin, Z.C.2    Lin, G.3    Banie, L.4    Lue, T.F.5    Lin, C.S.6
  • 15
    • 79952281382 scopus 로고    scopus 로고
    • Icariin induces mouse embryonic stem cell differentiation into beating functional cardiomyocytes
    • Sun X, Sun X, Jin X, Zhang X, Liu C, Lei L, et al. Icariin induces mouse embryonic stem cell differentiation into beating functional cardiomyocytes. Mol Cell Biochem 2011;349: 117-123.
    • (2011) Mol Cell Biochem , vol.349 , pp. 117-123
    • Sun, X.1    Sun, X.2    Jin, X.3    Zhang, X.4    Liu, C.5    Lei, L.6
  • 16
    • 84902286458 scopus 로고    scopus 로고
    • JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI
    • Li LL, Xue AM, Li BX, Shen YW, Li YH, Luo CL, et al. JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI. Breast Cancer Res 2014;16: R56.
    • (2014) Breast Cancer Res , vol.16 , pp. R56
    • Li, L.L.1    Xue, A.M.2    Li, B.X.3    Shen, Y.W.4    Li, Y.H.5    Luo, C.L.6
  • 17
  • 18
    • 78650842310 scopus 로고    scopus 로고
    • Driving the cell cycle with a minimal CDK control network
    • Coudreuse D, Nurse P. Driving the cell cycle with a minimal CDK control network. Nature 2010; 468:1074-1079.
    • (2010) Nature , vol.468 , pp. 1074-1079
    • Coudreuse, D.1    Nurse, P.2
  • 19
    • 84878950558 scopus 로고    scopus 로고
    • Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63
    • Liu L, Xu Y, Reiter RJ. Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63. Bone 2013; 55:432-438.
    • (2013) Bone , vol.55 , pp. 432-438
    • Liu, L.1    Xu, Y.2    Reiter, R.J.3
  • 20
    • 84894638878 scopus 로고    scopus 로고
    • Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells
    • Hu YP, Tan ZJ, Wu XS, Liu TY, Jiang L, Bao RF, et al. Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells. Molecules 2014; 19: 2612-2628.
    • (2014) Molecules , vol.19 , pp. 2612-2628
    • Hu, Y.P.1    Tan, Z.J.2    Wu, X.S.3    Liu, T.Y.4    Jiang, L.5    Bao, R.F.6
  • 21
    • 84906688501 scopus 로고    scopus 로고
    • Cordycepin induces s phase arrest and apoptosis in human gallbladder cancer cells
    • Wang XA, Xiang SS, Li HF, Wu XS, Li ML, Shu YJ, et al. Cordycepin induces s phase arrest and apoptosis in human gallbladder cancer cells. Molecules 2014; 19:11350-11365.
    • (2014) Molecules , vol.19 , pp. 11350-11365
    • Wang, X.A.1    Xiang, S.S.2    Li, H.F.3    Wu, X.S.4    Li, M.L.5    Shu, Y.J.6
  • 22
    • 84884895257 scopus 로고    scopus 로고
    • Characterization of cytosolic proliferating cell nuclear antigen (PCNA) in neutrophils: Antiapoptotic role of the monomer
    • De Chiara A, Pederzoli-Ribeil M, Mocek J, Candalh C, Mayeux P, Millet A, et al. Characterization of cytosolic proliferating cell nuclear antigen (PCNA) in neutrophils: Antiapoptotic role of the monomer. J Leukoc Biol 2013; 94:723-731.
    • (2013) J Leukoc Biol , vol.94 , pp. 723-731
    • De Chiara, A.1    Pederzoli-Ribeil, M.2    Mocek, J.3    Candalh, C.4    Mayeux, P.5    Millet, A.6
  • 23
    • 84881071322 scopus 로고    scopus 로고
    • Paracrine control of tissue regeneration and cell proliferation by Caspase-3
    • Boland K, Flanagan L, Prehn JH. Paracrine control of tissue regeneration and cell proliferation by Caspase-3. Cell Death Dis 2013; 4:e725.
    • (2013) Cell Death Dis , vol.4
    • Boland, K.1    Flanagan, L.2    Prehn, J.H.3
  • 24
    • 34247862359 scopus 로고    scopus 로고
    • Medulloblastoma: Tumorigenesis, current clinical paradigm, and efforts to improve risk stratification
    • Polkinghorn WR, Tarbell NJ. Medulloblastoma: Tumorigenesis, current clinical paradigm, and efforts to improve risk stratification. Nat Clin Pract Oncol 2007; 4:295-304.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 295-304
    • Polkinghorn, W.R.1    Tarbell, N.J.2
  • 25
    • 1642307767 scopus 로고    scopus 로고
    • Medulloblastoma: Signalling a change in treatment
    • Gilbertson RJ. Medulloblastoma: Signalling a change in treatment. Lancet Oncol 2004; 5:209-218.
    • (2004) Lancet Oncol , vol.5 , pp. 209-218
    • Gilbertson, R.J.1
  • 26
    • 10944257459 scopus 로고    scopus 로고
    • Molecular signaling regulating anchorage-independent growth of cancer cells
    • Wang LH. Molecular signaling regulating anchorage-independent growth of cancer cells. Mt Sinai J Med 2004; 71:361-367.
    • (2004) Mt Sinai J Med , vol.71 , pp. 361-367
    • Wang, L.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.