메뉴 건너뛰기




Volumn 127, Issue 15, 2016, Pages 1930-1939

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CAVEOLIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; CAV1 PROTEIN, HUMAN; CAV1 PROTEIN, MOUSE; CD28 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; SH2D2A PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84994815329     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-09-672428     Document Type: Article
Times cited : (43)

References (39)
  • 2
    • 0022591006 scopus 로고
    • Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones
    • Parkman R. Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones. J Immunol. 1986;136(10):3543-3548.
    • (1986) J Immunol. , vol.136 , Issue.10 , pp. 3543-3548
    • Parkman, R.1
  • 3
    • 0742288752 scopus 로고    scopus 로고
    • Specific donor Vbeta-associated CD4 T-cell responses correlate with severe acute graft-versus-host disease directed to multiple minor histocompatibility antigens
    • Jones SC, Friedman TM, Murphy GF, Korngold R. Specific donor Vbeta-associated CD4 T-cell responses correlate with severe acute graft-versus-host disease directed to multiple minor histocompatibility antigens. Biol Blood Marrow Transplant. 2004;10(2):91-105.
    • (2004) Biol Blood Marrow Transplant. , vol.10 , Issue.2 , pp. 91-105
    • Jones, S.C.1    Friedman, T.M.2    Murphy, G.F.3    Korngold, R.4
  • 4
    • 33846224785 scopus 로고    scopus 로고
    • Full activation of the T cell receptor requires both clustering and conformational changes at CD3
    • Minguet S, Swamy M, Alarcón B, Luescher IF, Schamel WW. Full activation of the T cell receptor requires both clustering and conformational changes at CD3. Immunity. 2007;26(1):43-54.
    • (2007) Immunity , vol.26 , Issue.1 , pp. 43-54
    • Minguet, S.1    Swamy, M.2    Alarcón, B.3    Luescher, I.F.4    Schamel, W.W.5
  • 5
    • 40149095444 scopus 로고    scopus 로고
    • The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function
    • Minguet S, Swamy M, Schamel WW. The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function. Immunol Lett. 2008;116(2):195-202.
    • (2008) Immunol Lett. , vol.116 , Issue.2 , pp. 195-202
    • Minguet, S.1    Swamy, M.2    Schamel, W.W.3
  • 6
    • 0026522204 scopus 로고
    • Profound block in thymocyte development in mice lacking p56lck
    • Molina TJ, Kishihara K, Siderovski DP, et al. Profound block in thymocyte development in mice lacking p56lck. Nature. 1992;357(6374):161-164.
    • (1992) Nature , vol.357 , Issue.6374 , pp. 161-164
    • Molina, T.J.1    Kishihara, K.2    Siderovski, D.P.3
  • 8
    • 0032577647 scopus 로고    scopus 로고
    • Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain
    • Engelman JA, Chu C, Lin A, et al. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett. 1998;428(3):205-211.
    • (1998) FEBS Lett. , vol.428 , Issue.3 , pp. 205-211
    • Engelman, J.A.1    Chu, C.2    Lin, A.3
  • 9
    • 4644280871 scopus 로고    scopus 로고
    • Interactions of EGFR and caveolin-1 in human glioblastoma cells: Evidence that tyrosine phosphorylation regulates EGFR association with caveolae
    • Abulrob A, Giuseppin S, Andrade MF, McDermid A, Moreno M, Stanimirovic D. Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae. Oncogene. 2004;23(41):6967-6979.
    • (2004) Oncogene , vol.23 , Issue.41 , pp. 6967-6979
    • Abulrob, A.1    Giuseppin, S.2    Andrade, M.F.3    McDermid, A.4    Moreno, M.5    Stanimirovic, D.6
  • 10
    • 80053088287 scopus 로고    scopus 로고
    • Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells
    • Tomassian T, Humphries LA, Liu SD, Silva O, Brooks DG, Miceli MC. Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells. J Immunol. 2011;187(6):2993-3002.
    • (2011) J Immunol. , vol.187 , Issue.6 , pp. 2993-3002
    • Tomassian, T.1    Humphries, L.A.2    Liu, S.D.3    Silva, O.4    Brooks, D.G.5    Miceli, M.C.6
  • 11
    • 59849094042 scopus 로고    scopus 로고
    • Sphingolipids and membrane environments for caveolin
    • Sonnino S, Prinetti A. Sphingolipids and membrane environments for caveolin. FEBS Lett. 2009;583(4):597-606.
    • (2009) FEBS Lett. , vol.583 , Issue.4 , pp. 597-606
    • Sonnino, S.1    Prinetti, A.2
  • 12
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 2000;1(1):31-39.
    • (2000) Nat Rev Mol Cell Biol. , vol.1 , Issue.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 13
    • 28144434857 scopus 로고    scopus 로고
    • Interactions between collagen IX and biglycan measured by atomic force microscopy
    • Chen C-H, Yeh M-L, Geyer M, et al. Interactions between collagen IX and biglycan measured by atomic force microscopy. Biochem Biophys Res Commun. 2006;339(1):204-208.
    • (2006) Biochem Biophys Res Commun. , vol.339 , Issue.1 , pp. 204-208
    • Chen, C.-H.1    Yeh, M.-L.2    Geyer, M.3
  • 14
    • 65649122726 scopus 로고    scopus 로고
    • Lattices, rafts, and scaffolds: Domain regulation of receptor signaling at the plasma membrane
    • Lajoie P, Goetz JG, Dennis JW, Nabi IR. Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol. 2009;185(3):381-385.
    • (2009) J Cell Biol. , vol.185 , Issue.3 , pp. 381-385
    • Lajoie, P.1    Goetz, J.G.2    Dennis, J.W.3    Nabi, I.R.4
  • 15
    • 0036830114 scopus 로고    scopus 로고
    • Multiple functions of caveolin-1
    • Liu P, Rudick M, Anderson RG. Multiple functions of caveolin-1. J Biol Chem. 2002;277(44):41295-41298.
    • (2002) J Biol Chem. , vol.277 , Issue.44 , pp. 41295-41298
    • Liu, P.1    Rudick, M.2    Anderson, R.G.3
  • 16
    • 16244399830 scopus 로고    scopus 로고
    • Caveolin-1 interacts directly with dynamin-2
    • Yao Q, Chen J, Cao H, et al. Caveolin-1 interacts directly with dynamin-2. J Mol Biol. 2005;348(2):491-501.
    • (2005) J Mol Biol. , vol.348 , Issue.2 , pp. 491-501
    • Yao, Q.1    Chen, J.2    Cao, H.3
  • 17
    • 0033973279 scopus 로고    scopus 로고
    • Identification of filamin as a novel ligand for caveolin-1: Evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton
    • Stahlhut M, van Deurs B. Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton. Mol Biol Cell. 2000;11(1):325-337.
    • (2000) Mol Biol Cell. , vol.11 , Issue.1 , pp. 325-337
    • Stahlhut, M.1    Van Deurs, B.2
  • 18
    • 0037088672 scopus 로고    scopus 로고
    • A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: Recruitment of C-terminal Src kinase
    • Cao H, Courchesne WE, Mastick CC. A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase. J Biol Chem. 2002;277(11):8771-8774.
    • (2002) J Biol Chem. , vol.277 , Issue.11 , pp. 8771-8774
    • Cao, H.1    Courchesne, W.E.2    Mastick, C.C.3
  • 19
    • 33745633856 scopus 로고    scopus 로고
    • Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production
    • Zeiser R, Nguyen VH, Beilhack A, et al. Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production. Blood. 2006;108(1):390-399.
    • (2006) Blood , vol.108 , Issue.1 , pp. 390-399
    • Zeiser, R.1    Nguyen, V.H.2    Beilhack, A.3
  • 20
    • 0141461418 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • Edinger M, Hoffmann P, Ermann J, et al. CD4+ CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med. 2003;9(9):1144-1150.
    • (2003) Nat Med. , vol.9 , Issue.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3
  • 21
    • 0016315350 scopus 로고
    • Histopathology of graft-vs.-host reaction (GvHR) in human recipients of marrow from HL-A-matched sibling donors
    • Lerner KG, Kao GF, Storb R, Buckner CD, Clift RA, Thomas ED. Histopathology of graft-vs.-host reaction (GvHR) in human recipients of marrow from HL-A-matched sibling donors. Transplant Proc. 1974;6(4):367-371.
    • (1974) Transplant Proc. , vol.6 , Issue.4 , pp. 367-371
    • Lerner, K.G.1    Kao, G.F.2    Storb, R.3    Buckner, C.D.4    Clift, R.A.5    Thomas, E.D.6
  • 22
    • 84879370407 scopus 로고    scopus 로고
    • Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100
    • Leonhardt F, Grundmann S, Behe M, et al. Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100. Blood. 2013;121(17):3307-3318.
    • (2013) Blood , vol.121 , Issue.17 , pp. 3307-3318
    • Leonhardt, F.1    Grundmann, S.2    Behe, M.3
  • 23
    • 0035964954 scopus 로고    scopus 로고
    • Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
    • Drab M, Verkade P, Elger M, et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science. 2001;293(5539):2449-2452.
    • (2001) Science , vol.293 , Issue.5539 , pp. 2449-2452
    • Drab, M.1    Verkade, P.2    Elger, M.3
  • 24
    • 79956258982 scopus 로고    scopus 로고
    • Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity
    • Hippen KL, Merkel SC, Schirm DK, et al. Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci Transl Med. 2011;3(83):83ra41.
    • (2011) Sci Transl Med. , vol.3 , Issue.83 , pp. 83ra41
    • Hippen, K.L.1    Merkel, S.C.2    Schirm, D.K.3
  • 25
    • 84908128612 scopus 로고    scopus 로고
    • MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD
    • Stickel N, Prinz G, Pfeifer D, et al. MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD. Blood. 2014;124(16):2586-2595.
    • (2014) Blood , vol.124 , Issue.16 , pp. 2586-2595
    • Stickel, N.1    Prinz, G.2    Pfeifer, D.3
  • 26
    • 84890363675 scopus 로고    scopus 로고
    • Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation
    • Jiao H, Zhang Y, Yan Z, et al. Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation. J Immunol. 2013;191(12):6191-6199.
    • (2013) J Immunol. , vol.191 , Issue.12 , pp. 6191-6199
    • Jiao, H.1    Zhang, Y.2    Yan, Z.3
  • 27
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25-T cells through Foxp3 induction and downregulation of Smad7
    • Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25-T cells through Foxp3 induction and downregulation of Smad7. J Immunol. 2004;172(9):5149-5153.
    • (2004) J Immunol. , vol.172 , Issue.9 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 29
    • 84868293703 scopus 로고    scopus 로고
    • KAP1 regulates gene networks controlling T-cell development and responsiveness
    • Santoni de Sio FR, Barde I, Offner S, et al. KAP1 regulates gene networks controlling T-cell development and responsiveness. FASEB J. 2012;26(11):4561-4575.
    • (2012) FASEB J , vol.26 , Issue.11 , pp. 4561-4575
    • Santoni De Sio, F.R.1    Barde, I.2    Offner, S.3
  • 30
    • 84888637943 scopus 로고    scopus 로고
    • Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane
    • Yang Y, Wolfram J, Shen J, et al. Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane. FEBS Lett. 2013;587(24):3912-3920.
    • (2013) FEBS Lett. , vol.587 , Issue.24 , pp. 3912-3920
    • Yang, Y.1    Wolfram, J.2    Shen, J.3
  • 31
    • 0035794218 scopus 로고    scopus 로고
    • Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor
    • Razani B, Zhang XL, Bitzer M, von Gersdorff G, Böttinger EP, Lisanti MP. Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor. J Biol Chem. 2001;276(9):6727-6738.
    • (2001) J Biol Chem. , vol.276 , Issue.9 , pp. 6727-6738
    • Razani, B.1    Zhang, X.L.2    Bitzer, M.3    Von Gersdorff, G.4    Böttinger, E.P.5    Lisanti, M.P.6
  • 32
    • 79952931627 scopus 로고    scopus 로고
    • Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells
    • Gabryšová L, Christensen JR, Wu X, Kissenpfennig A, Malissen B, O'Garra A. Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells. Eur J Immunol. 2011;41(5):1242-1248.
    • (2011) Eur J Immunol. , vol.41 , Issue.5 , pp. 1242-1248
    • Gabryšová, L.1    Christensen, J.R.2    Wu, X.3    Kissenpfennig, A.4    Malissen, B.5    O'Garra, A.6
  • 33
    • 77955391804 scopus 로고    scopus 로고
    • TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
    • Gottschalk RA, Corse E, Allison JP. TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med. 2010;207(8):1701-1711.
    • (2010) J Exp Med. , vol.207 , Issue.8 , pp. 1701-1711
    • Gottschalk, R.A.1    Corse, E.2    Allison, J.P.3
  • 35
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • Di Ianni M, Falzetti F, Carotti A, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood. 2011;117(14):3921-3928.
    • (2011) Blood , vol.117 , Issue.14 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3
  • 36
    • 82555168440 scopus 로고    scopus 로고
    • Interleukin-2 and regulatory T cells in graft-versus-host disease
    • Koreth J, Matsuoka K, Kim HT, et al. Interleukin-2 and regulatory T cells in graft-versus-host disease. N Engl J Med. 2011;365(22):2055-2066.
    • (2011) N Engl J Med. , vol.365 , Issue.22 , pp. 2055-2066
    • Koreth, J.1    Matsuoka, K.2    Kim, H.T.3
  • 37
    • 78751696183 scopus 로고    scopus 로고
    • Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
    • Brunstein CG, Miller JS, Cao Q, et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood. 2011;117(3):1061-1070.
    • (2011) Blood , vol.117 , Issue.3 , pp. 1061-1070
    • Brunstein, C.G.1    Miller, J.S.2    Cao, Q.3
  • 38
    • 84886624251 scopus 로고    scopus 로고
    • + T cell homeostasis but dispensable for regulatory T cell function
    • + T cell homeostasis but dispensable for regulatory T cell function. PLoS Biol. 2013;11(10):e1001674.
    • (2013) PLoS Biol. , vol.11 , Issue.10
    • Sledzińska, A.1    Hemmers, S.2    Mair, F.3
  • 39
    • 84896036640 scopus 로고    scopus 로고
    • Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation
    • Caton AJ, Kropf E, Simons DM, Aitken M, Weissler KA, Jordan MS. Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation. Eur J Immunol. 2014;44(3):785-793.
    • (2014) Eur J Immunol. , vol.44 , Issue.3 , pp. 785-793
    • Caton, A.J.1    Kropf, E.2    Simons, D.M.3    Aitken, M.4    Weissler, K.A.5    Jordan, M.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.