Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

Cell

Volumn 167, Issue 4, 2016, Pages 1041-1051.e11

  Zimmerman, Brandon ^a,b   Kelly, Brendan ^c   McMillan, Brian J ^a,b   Seegar, Tom C M ^a,b   Dror, Ron O ^c   Kruse, Andrew C ^a   Blacklow, Stephen C ^a,b,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

CD19; CD81; membrane protein; protein structure; protein trafficking; X ray crystallography

Indexed keywords

CD81 ANTIGEN; CHOLESTEROL; TETRASPANIN; CD81 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DENSITY; MOLECULAR DYNAMICS; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; REGULATORY MECHANISM; SIMULATION; CHEMICAL MODEL; CHEMISTRY; HUMAN; METABOLISM; X RAY CRYSTALLOGRAPHY;

ANTIGENS, CD81; BINDING SITES; CHOLESTEROL; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, CHEMICAL; MOLECULAR DYNAMICS SIMULATION;

EID: 84994766531     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.09.056     Document Type: Article

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