Effects of Helicobacter pylori eradication on insulin resistance and metabolic parameters: A systematic review and meta-analysis

European Journal of Gastroenterology and Hepatology

Volumn 29, Issue 2, 2017, Pages 153-159

  Upala, Sikarin ^a,c   Sanguankeo, Anawin ^a,c   Saleem, Sheikh A ^a   Jaruvongvanich, Veeravich ^b,d  

^a BASSETT MEDICAL CENTER   (United States)

^b UNIVERSITY OF HAWAII   (United States)

^c MAHIDOL UNIVERSITY   (Thailand)

^d KING CHULALONGKORN MEMORIAL HOSPITAL   (Thailand)

Author keywords

Helicobacter pylori; Helicobacter pylori eradication; Insulin resistance; Meta analysis

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; ANTIINFECTIVE AGENT; GLUCOSE BLOOD LEVEL; PROTON PUMP INHIBITOR;

ARTICLE; BACTERIAL CLEARANCE; BODY MASS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HELICOBACTER INFECTION; HOMEOSTASIS MODEL ASSESSMENT; HUMAN; INSULIN RESISTANCE; METABOLIC PARAMETERS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; CASE CONTROL STUDY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; META ANALYSIS; METABOLISM; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CHOLESTEROL, HDL; CHOLESTEROL, LDL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INSULIN RESISTANCE; PROTON PUMP INHIBITORS; TREATMENT OUTCOME; TRIGLYCERIDES; WAIST CIRCUMFERENCE;

EID: 84994719635     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/MEG.0000000000000774     Document Type: Article

References (35)

1. McColl KE. Clinical practice. Helicobacter pylori infection. N Engl J Med 2010;362:1597-1604.
2. Fallone CA, Chiba N, van Zanten SV, Fischbach L, Gisbert JP, Hunt RH, et al. The Toronto Consensus for the treatment of Helicobacter pylori infection in adults. Gastroenterology 2016;151:51.e14-69.e14.
3. Garza-Gonzalez E, Perez-Perez GI, Maldonado-Garza HJ, Bosques-Padilla FJ. A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication. World J Gastroenterol 2014;20:1438-1449.
4. Megraud F, Coenen S, Versporten A, Kist M, Lopez-Brea M, Hirschl AM, et al. Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. Gut 2013;62:34-42.
5. De Francesco V, Margiotta M, Zullo A, Hassan C, Giorgio F, Burattini O, et al. Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy. J Antimicrob Chemother 2007;59:783-785.
6. Thung I, Aramin H, Vavinskaya V, Gupta S, Park JY, Crowe SE, et al. Review article: the global emergence of Helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther 2016;43:514-533.
7. Haruma K, Okamoto S, Sumii K, Yoshihara M, Tari A, Teshima H, et al. Helicobacter pylori infection and gastroduodenal disease: a comparison of endoscopic findings, histology, and urease test data. Hiroshima J Med Sci 1992;41:65-70.
8. Kawaguchi H, Haruma K, Komoto K, Yoshihara M, Sumii K, Kajiyama G. Helicobacter pylori infection is the major risk factor for atrophic gastritis. Am J Gastroenterol 1996;91:959-962.
9. Azuma T, Suto H, Ito Y, Muramatsu A, Ohtani M, Dojo M, et al. Eradication of Helicobacter pylori infection induces an increase in body mass index. Aliment Pharmacol Ther 2002;16(Suppl 2):240-244.
10. Fujiwara Y, Higuchi K, Arafa UA, Uchida T, Tominaga K, Watanabe T, et al. Long-term effect of Helicobacter pylori eradication on quality of life, body mass index, and newly developed diseases in Japanese patients with peptic ulcer disease. Hepatogastroenterology 2002;49:1298-1302.
11. Gunji T, Matsuhashi N, Sato H, Fujibayashi K, Okumura M, Sasabe N, et al. Helicobacter pylori infection is significantly associated with metabolic syndrome in the Japanese population. Am J Gastroenterol 2008;103:3005-3010.
12. Ozdem S, Akcam M, Yilmaz A, Artan R. Insulin resistance in children with Helicobacter pylori infection. J Endocrinol Invest 2007;30:236-240.
13. Gen R, Demir M, Ataseven H. Effect of Helicobacter pylori eradication on insulin resistance, serum lipids and low-grade inflammation. South Med J 2010;103:190-196.
14. Ando T, Ishikawa T, Takagi T, Imamoto E, Kishimoto E, Okajima A, et al. Impact of Helicobacter pylori eradication on circulating adiponectin in humans. Helicobacter 2013;18:158-164.
15. Park SH, Jeon WK, Kim SH, Kim HJ, Park DI, Cho YK, et al. Helicobacter pylori eradication has no effect on metabolic and inflammatory parameters. J Natl Med Assoc 2005;97:508-513.
16. Jamali R, Mofid A, Vahedi H, Farzaneh R, Dowlatshahi S. The effect of helicobacter pylori eradication on liver fat content in subjects with nonalcoholic fatty liver disease: a randomized open-label clinical trial. Hepat Mon 2013;13:e14679.
17. Higgins JPT, Green S. Cochrane Collaboration. Cochrane handbook for systematic reviews of interventions. Chichester, England; Hoboken, NJ: Wiley-Blackwell; 2008.
18. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000;283:2008-2012.
19. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 2010;25:603-605.
20. Sterne JA, Egger M. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 2001;54:1046-1055.
21. Kamada T, Hata J, Kusunoki H, Ito M, Tanaka S, Kawamura Y, et al. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients. Dig Liver Dis 2005;37:39-43.
22. Asaka M, Kato M, Sugiyama T, Satoh K, Kuwayama H, Fukuda Y, et al. Follow-up survey of a large-scale multicenter, double-blind study of triple therapy with lansoprazole, amoxicillin, and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients. J Gastroenterol 2003;38:339-347.
23. Verma S, Giaffer MH. Helicobacter pylori eradication ameliorates symptoms and improves quality of life in patients on long-term acid suppression. A large prospective study in primary care. Dig Dis Sci 2002;47:1567-1574.
24. van Dieren S, Beulens JW, van der Schouw YT, Grobbee DE, Neal B. The global burden of diabetes and its complications: an emerging pandemic. Eur J Cardiovasc Prev Rehabil 2010;17(Suppl 1):S3-S8.
25. Azuma T, Suto H, Ito Y, Ohtani M, Dojo M, Kuriyama M, et al. Gastric leptin and Helicobacter pylori infection. Gut 2001;49:324-329.
26. Francois F, Roper J, Joseph N, Pei Z, Chhada A, Shak JR, et al. The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin. BMC Gastroenterol 2011;11:37.
27. Nwokolo CU, Freshwater DA, O'Hare P, Randeva HS. Plasma ghrelin following cure of Helicobacter pylori. Gut 2003;52:637-640.
28. Franceschi F, Annalisa T, Teresa DR, Giovanna D, Ianiro G, Franco S, et al. Role of Helicobacter pylori infection on nutrition and metabolism. World J Gastroenterol 2014;20:12809-12817.
29. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7:941-946.
30. Cohen B, Novick D, Rubinstein M. Modulation of insulin activities by leptin. Science 1996;274:1185-1188.
31. Fischer S, Hanefeld M, Haffner SM, Fusch C, Schwanebeck U, Kohler C, et al. Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass. Acta Diabetol 2002;39:105-110.
32. Wang C, Guan Y, Yang J. Cytokines in the progression of pancreatic beta-cell dysfunction. Int J Endocrinol 2010;2010:515136.
33. Guldstrand M, Ahren B, Adamson U. Improved beta-cell function after standardized weight reduction in severely obese subjects. Am J Physiol Endocrinol Metab 2003;284:E557-E565.
34. Astrup A, Finer N. Redefining type 2 diabetes: 'diabesity' or 'obesity dependent diabetes mellitus'? Obes Rev 2000;1:57-59.
35. Yang YJ, Sheu BS, Yang HB, Lu CC, Chuang CC. Eradication of Helicobacter pylori increases childhood growth and serum acylated ghrelin levels. World J Gastroenterol 2012;18:2674-2681.