Helicobacter pylori eradication has no effect on metabolic and inflammatory parameters

Journal of the National Medical Association

Volumn 97, Issue 4, 2005, Pages 508-513

  Park, Seung Ha ^a,b   Jeon, Woo Kyu ^a,b   Kim, Sang Hoon ^a,b   Kim, Hong Joo ^a,b   Park II, Dong ^a,b   Cho, Yong Kyun ^a,b   Sung, In Kyung ^a,b   Sohn II, Chong ^a,b   Kim, Byung Ik ^a,b   Keum, Dong Keuk ^a,b  

^a Sungkyunkwan Univ Sch of Medicine ^*

^b School of Medicine   (South Korea)

Author keywords

Coronary heart disease; Eradication; Helicobacter pylori

Indexed keywords

AMOXICILLIN; C REACTIVE PROTEIN; CLARITHROMYCIN; GLUCOSE; LIPID; LIPOPROTEIN; OMEPRAZOLE;

ADULT; AGED; ATHEROGENESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ERADICATION THERAPY; FEMALE; GLUCOSE BLOOD LEVEL; HEALTH SURVEY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; INFLAMMATION; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; LEUKOCYTE COUNT; LIPID BLOOD LEVEL; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; METABOLISM; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; RISK ASSESSMENT;

ADULT; AGED; ANTI-BACTERIAL AGENTS; CASE-CONTROL STUDIES; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FEMALE; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INFLAMMATION MEDIATORS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PROBABILITY; PROGNOSIS; REFERENCE VALUES; RETROSPECTIVE STUDIES; RISK ASSESSMENT;

EID: 20144389442     PISSN: 00279684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (18)

1. Strachan DP, Mendall MA, Carrington D, et al. Relation of Helicobacter pylori infection to 13-year mortality and incident ischemic heart disease in the Caerphilly Prospective Heart Disease Study. Circulation. 1998;98:1286-1290.
2. Danesh J, Peto R. Risk factors for coronary heart disease and infection with Helicobacter pylori: meta-analysis of 18 studies. Br Med J. 1998;316: 1130-1132.
3. Niemela S, Karttunen T, Khortonen T, et al. Could Helicobacter pylori increase the risk of coronary heart disease by modifying serum lipid concentrations? Heart. 1996;75:573-575.
4. Zhu J, Quyyumi A, Muhlestein JB, et al. Lack of association of Helicobacter pylori infection with coronary artery disease and frequency of acute myocardial infarction or death. Am J Cardiol. 2002;89:155-158.
5. Rengstrom J, Jovinge S, Bavenholm P, et al. Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degrees of coronary artery disease. J Intern Med. 1998;243:109-113.
6. Parente F, Imbesi V, Cucino C, et al. Helicobacter pylori CagA seropositivity does not influence inflammatory parameters, lipid concentrations and hemostatic factors in healthy individuals. J Intern Med. 2000;247:213-217.
7. Laurila A, Bloigu A, Nayha S, et al. Association of Helicobacter pylori infection with elevated serum lipids. Atherosclerosis. 1999;142:207-210.
8. Hoffmeister A, Rothenbacher D, Bode G, et al. Current infection with Helicobacter pylori but not seropositivity to Chlamydia pneumoniae or Cytomegalovirus is associated with an atherogenic, modified lipid profile. Atheroscl Thromb Vasc Biol. 2001;21:427-432.
9. Torgano G, Cosentini R, Mandelli C, et al. Treatment of Helicobacter pylori and Chlamydia pneumoniae infections decreases fibrinogen plasma level in patients with ischemic heart disease. Circulation. 1999;99:1555-1559.
10. Stone AF, Mendall MA, Kaski JC, et al. Effect of treatment for Chlamydia pneumoniae and Helicobacter pylori on markers of inflammation and cardiac events in patients with acute coronary syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA). Circulation. 2002;106:1219-1223.
11. Scharnagl H, Kist M, Grawitz AB, et al. Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol. Am J Cardiol. 2004;93:219-220.
12. Mathews DR, Hoskers JP, Rudenski AS, et al. Homeostasis model assessment of insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-419.
13. Ernst PB, Crowe SA, Reyes VE. How does Helicobacter pylori cause mucosal damage? The inflammatory response. Gastroenterology. 1997; 113:535-542.
14. Mendall MA, Patel P, Asante M, et al. Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart. 1997;78:273-277.
15. Treiber G. Decrease of plasma fibrinogen after eradication of Helicobacter pylori infection in patients with ischemic heart disease. Heart. 1999;82:646.
16. Ianaro A, Ialenti A, Maffia P, et al. Anti-inflammatory activity of macrolide antibiotics. J Pharmacol Exp Ther. 2000;292:156-163.
17. Furuta T, Shirai N, Xiao F, et al. Effect of Helicobacter pylori infection and its eradication on nutrition. Aliment Pharmacol Ther. 2002;16:799-806.
18. Nwokolo CU, Freshwater DA, O'Hare P, et al. Plasma ghrelin following cure of Helicobacter pylori. Gut. 2003;52:637-640.