Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lepob/ob mice

Molecular Metabolism

Volumn 5, Issue 11, 2016, Pages 1103-1112

  D'souza, Anna M ^a   Johnson, James D ^a   Clee, Susanne M ^a   Kieffer, Timothy J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Hyperglycemia; Hyperinsulinemia; Lepob ob; Obesity

Indexed keywords

GLUCOSE; INSULIN; LEPTIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CELL STRUCTURE; DIABETES MELLITUS; DISEASE COURSE; FAT MASS; GENETIC INSULIN REDUCTION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; LEPTIN DEFICIENCY; MALE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT GAIN; ANIMAL; GENETICS; HYPERINSULINISM; METABOLISM;

ANIMALS; DIABETES MELLITUS; HYPERINSULINISM; INSULIN; LEPTIN; MICE; OBESITY;

EID: 84994709896     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2016.09.007     Document Type: Article

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