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Volumn 157, Issue 3, 2016, Pages 1007-1012

Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; CHOLESTEROL; CORTICOSTERONE; FATTY ACID; GLUCOSE; INSULIN; INSULIN GLARGINE; LEPTIN; TRIACYLGLYCEROL; GLUCAGON; GLUCOSE BLOOD LEVEL; GLYCEROL; INS1 PROTEIN, MOUSE; INS2 PROTEIN, MOUSE; INSULIN RECEPTOR; PEPTIDE; S961 PEPTIDE;

EID: 84960538941     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1890     Document Type: Article
Times cited : (22)

References (12)
  • 1
    • 84904000735 scopus 로고    scopus 로고
    • Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
    • Perry RJ, Zhang XM, Zhang D, et al. Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Med. 2014;20:759-763.
    • (2014) Nat Med. , vol.20 , pp. 759-763
    • Perry, R.J.1    Zhang, X.M.2    Zhang, D.3
  • 2
    • 84883483789 scopus 로고    scopus 로고
    • Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin
    • Fujikawa T, Berglund ED, Patel VR, et al. Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin. Cell Metab. 2013;18:431-444.
    • (2013) Cell Metab. , vol.18 , pp. 431-444
    • Fujikawa, T.1    Berglund, E.D.2    Patel, V.R.3
  • 3
    • 79959421553 scopus 로고    scopus 로고
    • Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling
    • Denroche HC, Levi J, Wideman RD, et al. Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling. Diabetes. 2011;60:1414-1423.
    • (2011) Diabetes , vol.60 , pp. 1414-1423
    • Denroche, H.C.1    Levi, J.2    Wideman, R.D.3
  • 4
    • 79951638003 scopus 로고    scopus 로고
    • Leptin activates a novel CNS mechanism for insulin-independent normalizationofsevere diabetic hyperglycemia
    • German JP, Thaler JP, Wisse BE, et al. Leptin activates a novel CNS mechanism for insulin-independent normalizationofsevere diabetic hyperglycemia. Endocrinology. 2011;152:394-404.
    • (2011) Endocrinology , vol.152 , pp. 394-404
    • German, J.P.1    Thaler, J.P.2    Wisse, B.E.3
  • 5
    • 77950373635 scopus 로고    scopus 로고
    • Leptin therapy in insulindeficient type I diabetes
    • Wang MY, Chen L, Clark GO, et al. Leptin therapy in insulindeficient type I diabetes. Proc Natl Acad Sci USA. 2010;107:4813-4819.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 4813-4819
    • Wang, M.Y.1    Chen, L.2    Clark, G.O.3
  • 6
    • 77954269929 scopus 로고    scopus 로고
    • Leptin deficiency causes insulin resistance induced byuncontrolled diabetes
    • German JP, Wisse BE, Thaler JP, et al. Leptin deficiency causes insulin resistance induced byuncontrolled diabetes. Diabetes. 2010;59:1626-1634.
    • (2010) Diabetes , vol.59 , pp. 1626-1634
    • German, J.P.1    Wisse, B.E.2    Thaler, J.P.3
  • 7
    • 52949140814 scopus 로고    scopus 로고
    • Making insulindeficient type 1 diabetic rodents thrive without insulin
    • Yu X, Park BH, Wang MY, Wang ZV, Unger RH. Making insulindeficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci USA. 2008;105:14070-14075.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14070-14075
    • Yu, X.1    Park, B.H.2    Wang, M.Y.3    Wang, Z.V.4    Unger, R.H.5
  • 8
    • 84940006145 scopus 로고    scopus 로고
    • Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol
    • Denroche HC, Kwon MM, Quong WL, et al. Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol. Diabetologia. 2015;58:1100-1108.
    • (2015) Diabetologia , vol.58 , pp. 1100-1108
    • Denroche, H.C.1    Kwon, M.M.2    Quong, W.L.3
  • 9
    • 0031010659 scopus 로고    scopus 로고
    • Phenotypic alterations in insulin-deficient mutant mice
    • Duvillié B, Cordonnier N, Deltour L, et al. Phenotypic alterations in insulin-deficient mutant mice. Proc Natl Acad Sci USA. 1997;94:5137-5140.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5137-5140
    • Duvillié, B.1    Cordonnier, N.2    Deltour, L.3
  • 10
    • 79551600048 scopus 로고    scopus 로고
    • Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice
    • Lee Y, Wang MY, Du XQ, Charron MJ, Unger RH. Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice. Diabetes. 2011;60:391-397.
    • (2011) Diabetes , vol.60 , pp. 391-397
    • Lee, Y.1    Wang, M.Y.2    Du, X.Q.3    Charron, M.J.4    Unger, R.H.5
  • 11
    • 78049271280 scopus 로고    scopus 로고
    • Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
    • Fujikawa T, Chuang JC, Sakata I, Ramadori G, Coppari R. Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice. Proc Natl Acad Sci USA. 2010;107:17391-17396.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17391-17396
    • Fujikawa, T.1    Chuang, J.C.2    Sakata, I.3    Ramadori, G.4    Coppari, R.5
  • 12
    • 84948843974 scopus 로고    scopus 로고
    • Evidence against hypothalamic-pituitary-adrenal axis suppression in the antidiabetic action of leptin
    • Morton GJ, Meek TH, Matsen ME, Schwartz MW. Evidence against hypothalamic-pituitary-adrenal axis suppression in the antidiabetic action of leptin. J Clin Invest. 2015; 2015.
    • (2015) J Clin Invest. , pp. 2015
    • Morton, G.J.1    Meek, T.H.2    Matsen, M.E.3    Schwartz, M.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.