-
1
-
-
0041842613
-
Recent advances in the pathophysiology of ischemic acute renal failure
-
Bonventre JV, Weinberg JM: Recent advances in the pathophysiology of ischemic acute renal failure. J AmSocNephrol 14: 2199-2210, 2003
-
(2003)
J AmSocNephrol
, vol.14
, pp. 2199-2210
-
-
Bonventre, J.V.1
Weinberg, J.M.2
-
2
-
-
65349114100
-
Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia
-
Geng H, Lan R, Wang G, Siddiqi AR, Naski MC, Brooks AI, Barnes JL, Saikumar P, Weinberg JM, Venkatachalam MA: Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia. Am J Pathol 174: 1291-1308, 2009
-
(2009)
Am J Pathol
, vol.174
, pp. 1291-1308
-
-
Geng, H.1
Lan, R.2
Wang, G.3
Siddiqi, A.R.4
Naski, M.C.5
Brooks, A.I.6
Barnes, J.L.7
Saikumar, P.8
Weinberg, J.M.9
Venkatachalam, M.A.10
-
3
-
-
84866516950
-
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGFB andCTGF through LPA2- andGaq-mediated Rho and avb6 integrindependent activation of TGF-b
-
Geng H, Lan R, Singha PK, Gilchrist A, Weinreb PH, Violette SM, Weinberg JM, Saikumar P, Venkatachalam MA: Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGFB andCTGF through LPA2- andGaq-mediated Rho and avb6 integrindependent activation of TGF-b. Am J Pathol 181: 1236-1249, 2012
-
(2012)
Am J Pathol
, vol.181
, pp. 1236-1249
-
-
Geng, H.1
Lan, R.2
Singha, P.K.3
Gilchrist, A.4
Weinreb, P.H.5
Violette, S.M.6
Weinberg, J.M.7
Saikumar, P.8
Venkatachalam, M.A.9
-
4
-
-
84860520663
-
PTEN loss defines a TGF-b-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis
-
Lan R, Geng H, Polichnowski AJ, Singha PK, Saikumar P, McEwen DG, Griffin KA, Koesters R, Weinberg JM, Bidani AK, KrizW, Venkatachalam MA: PTEN loss defines a TGF-b-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. Am J Physiol Renal Physiol 302: F1210-F1223, 2012
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F1210-F1223
-
-
Lan, R.1
Geng, H.2
Polichnowski, A.J.3
Singha, P.K.4
Saikumar, P.5
McEwen, D.G.6
Griffin, K.A.7
Koesters, R.8
Weinberg, J.M.9
Bidani, A.K.10
Kriz, W.11
Venkatachalam, M.A.12
-
5
-
-
77952174830
-
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
-
Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV: Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med 16: 535-543, 2010
-
(2010)
Nat Med
, vol.16
, pp. 535-543
-
-
Yang, L.1
Besschetnova, T.Y.2
Brooks, C.R.3
Shah, J.V.4
Bonventre, J.V.5
-
6
-
-
84925869881
-
Pathophysiology of acute kidney injury to chronic kidneydisease:Maladaptive repair
-
Yang L, Humphreys BD, Bonventre JV: Pathophysiology of acute kidney injury to chronic kidneydisease:Maladaptive repair.ContribNephrol 174: 149-155, 2011
-
(2011)
ContribNephrol
, vol.174
, pp. 149-155
-
-
Yang, L.1
Humphreys, B.D.2
Bonventre, J.V.3
-
7
-
-
84938948961
-
Lysophosphatidic acid (LPA) transactivates epidermal growth factor receptors (EGFR) via LPAR1/Gai/o signaling to potentiate LPAR2/ Gaq/avb6 integrin dependent TGFb signaling and increase the production of PDGF-B and CTGF by proximal tubule (PT) cells [abstract]
-
Geng H, Lan R, Singha PK, Saikumar P, Weinberg JM, Venkatachalam MA: Lysophosphatidic acid (LPA) transactivates epidermal growth factor receptors (EGFR) via LPAR1/Gai/o signaling to potentiate LPAR2/ Gaq/avb6 integrin dependent TGFb signaling and increase the production of PDGF-B and CTGF by proximal tubule (PT) cells [abstract]. J Am Soc Nephrol 24: 115A, 2013
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 115A
-
-
Geng, H.1
Lan, R.2
Singha, P.K.3
Saikumar, P.4
Weinberg, J.M.5
Venkatachalam, M.A.6
-
8
-
-
0021619876
-
Enzymedistribution along the nephron
-
GuderWG, Ross BD: Enzymedistribution along the nephron. Kidney Int 26: 101-111, 1984
-
(1984)
Kidney Int
, vol.26
, pp. 101-111
-
-
Guder, W.G.1
Ross, B.D.2
-
9
-
-
67449083683
-
Illuminating mitochondrial function and dysfunction using multiphoton technology
-
Weinberg JM, Molitoris BA: Illuminating mitochondrial function and dysfunction using multiphoton technology. J Am Soc Nephrol 20: 1164-1166, 2009
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1164-1166
-
-
Weinberg, J.M.1
Molitoris, B.A.2
-
10
-
-
84925284486
-
Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development
-
Kang HM, Ahn SH, Choi P, Ko YA, Han SH, Chinga F, Park AS, Tao J, Sharma K, Pullman J, Bottinger EP, Goldberg IJ, Susztak K: Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development. Nat Med 21: 37-46, 2015
-
(2015)
Nat Med
, vol.21
, pp. 37-46
-
-
Kang, H.M.1
Ahn, S.H.2
Choi, P.3
Ko, Y.A.4
Han, S.H.5
Chinga, F.6
Park, A.S.7
Tao, J.8
Sharma, K.9
Pullman, J.10
Bottinger, E.P.11
Goldberg, I.J.12
Susztak, K.13
-
11
-
-
0014854167
-
Shift toward anaerobic glycolysis in the regenerating rat kidney
-
Ash SR, Cuppage FE: Shift toward anaerobic glycolysis in the regenerating rat kidney. Am J Pathol 60: 385-402, 1970
-
(1970)
Am J Pathol
, vol.60
, pp. 385-402
-
-
Ash, S.R.1
Cuppage, F.E.2
-
12
-
-
0025941814
-
Interstitial lactate, inosine and hypoxanthine in rat kidney during normothermic ischaemia and recirculation
-
Eklund T, Wahlberg J, Ungerstedt U, Hillered L: Interstitial lactate, inosine and hypoxanthine in rat kidney during normothermic ischaemia and recirculation. Acta Physiol Scand 143: 279-286, 1991
-
(1991)
Acta Physiol Scand
, vol.143
, pp. 279-286
-
-
Eklund, T.1
Wahlberg, J.2
Ungerstedt, U.3
Hillered, L.4
-
13
-
-
0026284711
-
Changes in activities and mRNA levels of glycolytic enzymes of ischemia-reperfused rat kidney
-
Fukuhara Y, Yamamoto S, Yano F,Orita Y, Fujiwara Y, Ueda N, Kamada T, Noguchi T, Tanaka T: Changes in activities and mRNA levels of glycolytic enzymes of ischemia-reperfused rat kidney. Contrib Nephrol 95: 222-228, 1991
-
(1991)
Contrib Nephrol
, vol.95
, pp. 222-228
-
-
Fukuhara, Y.1
Yamamoto, S.2
Yano, F.3
Orita, Y.4
Fujiwara, Y.5
Ueda, N.6
Kamada, T.7
Noguchi, T.8
Tanaka, T.9
-
14
-
-
0029797552
-
Autocrine production and TGF-beta 1-mediated effects onmetabolismand viability in renal cells
-
Nowak G, Schnellmann RG: Autocrine production and TGF-beta 1-mediated effects onmetabolismand viability in renal cells.AmJ Physiol 271: F689-F697, 1996
-
(1996)
Am J Physiol
, vol.271
, pp. F689-F697
-
-
Nowak, G.1
Schnellmann, R.G.2
-
15
-
-
33749422045
-
Physiological oxygenation status is required for fully differentiated phenotype in kidney cortex proximal tubules
-
de Laplanche E, Gouget K, Cléris G, Dragounoff F, Demont J, Morales A, Bezin L, Godinot C, Perrière G, Mouchiroud D, Simonnet H: Physiological oxygenation status is required for fully differentiated phenotype in kidney cortex proximal tubules.AmJ Physiol Renal Physiol 291: F750-F760, 2006
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, pp. F750-F760
-
-
De Laplanche, E.1
Gouget, K.2
Cléris, G.3
Dragounoff, F.4
Demont, J.5
Morales, A.6
Bezin, L.7
Godinot, C.8
Perrière, G.9
Mouchiroud, D.10
Simonnet, H.11
-
16
-
-
52949142730
-
Mpv17l protects againstmitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease
-
Krick S, Shi S, Ju W, Faul C, Tsai SY, Mundel P, Böttinger EP: Mpv17l protects againstmitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease. ProcNatl Acad Sci U S A 105: 14106-14111, 2008
-
(2008)
ProcNatl Acad Sci U S A
, vol.105
, pp. 14106-14111
-
-
Krick, S.1
Shi, S.2
Ju, W.3
Faul, C.4
Tsai, S.Y.5
Mundel, P.6
Böttinger, E.P.7
-
17
-
-
0025285633
-
Differential effects of respiratory inhibitors on glycolysis in proximal tubules
-
Dickman KG,Mandel LJ: Differential effects of respiratory inhibitors on glycolysis in proximal tubules. Am J Physiol 258: F1608-F1615, 1990
-
(1990)
Am J Physiol
, vol.258
, pp. F1608-F1615
-
-
Dickman, K.G.1
Mandel, L.J.2
-
19
-
-
84864150374
-
Transforming growth factor-b, bioenergetics, and mitochondria in renal disease
-
Casalena G, Daehn I, Bottinger E: Transforming growth factor-b, bioenergetics, and mitochondria in renal disease. SeminNephrol 32: 295-303, 2012
-
(2012)
SeminNephrol
, vol.32
, pp. 295-303
-
-
Casalena, G.1
Daehn, I.2
Bottinger, E.3
-
20
-
-
84872341338
-
Mitochondrial reactive oxygen species regulate transforming growth factor-b signaling
-
Jain M, Rivera S, Monclus EA, Synenki L, Zirk A, Eisenbart J, Feghali-Bostwick C, Mutlu GM, Budinger GR, Chandel NS: Mitochondrial reactive oxygen species regulate transforming growth factor-b signaling. J Biol Chem 288: 770-777, 2013
-
(2013)
J Biol Chem
, vol.288
, pp. 770-777
-
-
Jain, M.1
Rivera, S.2
Monclus, E.A.3
Synenki, L.4
Zirk, A.5
Eisenbart, J.6
Feghali-Bostwick, C.7
Mutlu, G.M.8
Budinger, G.R.9
Chandel, N.S.10
-
21
-
-
84856821006
-
Signal transduction by mitochondrial oxidants
-
Finkel T: Signal transduction by mitochondrial oxidants. J Biol Chem 287: 4434-4440, 2012
-
(2012)
J Biol Chem
, vol.287
, pp. 4434-4440
-
-
Finkel, T.1
-
22
-
-
0035144846
-
Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat
-
Suzuki T, Kimura M, Asano M, Fujigaki Y, Hishida A: Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat. Am J Pathol 158: 75-85, 2001
-
(2001)
Am J Pathol
, vol.158
, pp. 75-85
-
-
Suzuki, T.1
Kimura, M.2
Asano, M.3
Fujigaki, Y.4
Hishida, A.5
-
23
-
-
0023618920
-
Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney
-
Gröne HJ,Weber K,Gröne E, Helmchen U,OsbornM: Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney. Am J Pathol 129: 1-8, 1987
-
(1987)
Am J Pathol
, vol.129
, pp. 1-8
-
-
Gröne, H.J.1
Weber, K.2
Gröne, E.3
Helmchen, U.4
Osborn, M.5
-
24
-
-
0026687709
-
Vimentin metaplasia in renal cortical tubules of preneoplastic, neoplastic, aging, and regenerative lesions of rats and humans
-
Ward JM, Stevens JL, Konishi N, Kurata Y, Uno H, Diwan BA,Ohmori T: Vimentin metaplasia in renal cortical tubules of preneoplastic, neoplastic, aging, and regenerative lesions of rats and humans.AmJ Pathol 141: 955-964, 1992
-
(1992)
Am J Pathol
, vol.141
, pp. 955-964
-
-
Ward, J.M.1
Stevens, J.L.2
Konishi, N.3
Kurata, Y.4
Uno, H.5
Diwan, B.A.6
Ohmori, T.7
-
25
-
-
84907209245
-
Severe renal mass reduction impairs recovery and promotes fibrosis after AKI
-
Polichnowski AJ, Lan R, Geng H, Griffin KA, VenkatachalamMA, Bidani AK: Severe renal mass reduction impairs recovery and promotes fibrosis after AKI. J Am Soc Nephrol 25: 1496-1507, 2014
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 1496-1507
-
-
Polichnowski, A.J.1
Lan, R.2
Geng, H.3
Griffin, K.A.4
Venkatachalam, M.A.5
Bidani, A.K.6
-
26
-
-
0015925389
-
Ultrastructure of the proximal convoluted tubules during repair following hormonally induced necrosis in rat kidney
-
Ormos J, Elemér G, Csapó Z: Ultrastructure of the proximal convoluted tubules during repair following hormonally induced necrosis in rat kidney. Virchows Arch B Cell Pathol Incl Mol Pathol 13: 1-13, 1973
-
(1973)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.13
, pp. 1-13
-
-
Ormos, J.1
Elemér, G.2
Csapó, Z.3
-
27
-
-
0014230145
-
A light and electronmicroscopic study of renal tubular regeneration
-
Kempczinski RF, Caulfield JB: A light and electronmicroscopic study of renal tubular regeneration. Nephron 5: 249-264, 1968
-
(1968)
Nephron
, vol.5
, pp. 249-264
-
-
Kempczinski, R.F.1
Caulfield, J.B.2
-
28
-
-
0018142634
-
Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments
-
Venkatachalam MA, Bernard DB, Donohoe JF, Levinsky NG: Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments. Kidney Int 14: 31-49, 1978
-
(1978)
Kidney Int
, vol.14
, pp. 31-49
-
-
Venkatachalam, M.A.1
Bernard, D.B.2
Donohoe, J.F.3
Levinsky, N.G.4
-
29
-
-
79952339999
-
Mitochondrial biogenesis in kidney disease
-
Weinberg JM: Mitochondrial biogenesis in kidney disease. J Am Soc Nephrol 22: 431-436, 2011
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 431-436
-
-
Weinberg, J.M.1
-
30
-
-
67049118905
-
Renal gene and protein expression signatures for prediction of kidney disease progression
-
Ju W, Eichinger F, Bitzer M, Oh J, McWeeney S, Berthier CC, Shedden K, Cohen CD, Henger A, Krick S, Kopp JB, Stoeckert CJ Jr., Dikman S, Schröppel B, Thomas DB, Schlondorff D, Kretzler M, Böttinger EP: Renal gene and protein expression signatures for prediction of kidney disease progression. Am J Pathol 174: 2073-2085, 2009
-
(2009)
Am J Pathol
, vol.174
, pp. 2073-2085
-
-
Ju, W.1
Eichinger, F.2
Bitzer, M.3
Oh, J.4
McWeeney, S.5
Berthier, C.C.6
Shedden, K.7
Cohen, C.D.8
Henger, A.9
Krick, S.10
Kopp, J.B.11
Stoeckert, C.J.12
Dikman, S.13
Schröppel, B.14
Thomas, D.B.15
Schlondorff, D.16
Kretzler, M.17
Böttinger, E.P.18
-
31
-
-
84858204846
-
Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival
-
Conde E, Alegre L, Blanco-Sánchez I, Sáenz-Morales D, Aguado-Fraile E, Ponte B, Ramos E, Sáiz A, Jiménez C, Ordoñez A, López-Cabrera M, del Peso L, de Landázuri MO, Liaño F, Selgas R, Sanchez-Tomero JA, García-Bermejo ML: Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival. PLoS One 7: e33258, 2012
-
(2012)
PLoS One
, vol.7
, pp. e33258
-
-
Conde, E.1
Alegre, L.2
Blanco-Sánchez, I.3
Sáenz-Morales, D.4
Aguado-Fraile, E.5
Ponte, B.6
Ramos, E.7
Sáiz, A.8
Jiménez, C.9
Ordoñez, A.10
López-Cabrera, M.11
Del Peso, L.12
De Landázuri, M.O.13
Liaño, F.14
Selgas, R.15
Sanchez-Tomero, J.A.16
García-Bermejo, M.L.17
-
33
-
-
2542601328
-
Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target
-
Potter C, Harris AL: Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target. Cell Cycle 3: 164-167, 2004
-
(2004)
Cell Cycle
, vol.3
, pp. 164-167
-
-
Potter, C.1
Harris, A.L.2
-
34
-
-
0026642691
-
Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies
-
Domingo M, Einig C, Eigenbrodt E, Reinacher M: Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies. J Histochem Cytochem 40: 665-673, 1992
-
(1992)
J Histochem Cytochem
, vol.40
, pp. 665-673
-
-
Domingo, M.1
Einig, C.2
Eigenbrodt, E.3
Reinacher, M.4
-
35
-
-
0022466294
-
Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex
-
Schering B, Reinacher M, Schoner W: Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex. BiochimBiophys Acta 881: 62-71, 1986
-
(1986)
BiochimBiophys Acta
, vol.881
, pp. 62-71
-
-
Schering, B.1
Reinacher, M.2
Schoner, W.3
-
37
-
-
0037303729
-
Chronic renal hypoxia after acute ischemic injury: Effects of L-arginine on hypoxia and secondary damage
-
Basile DP, Donohoe DL, Roethe K, Mattson DL: Chronic renal hypoxia after acute ischemic injury: Effects of L-arginine on hypoxia and secondary damage. Am J Physiol Renal Physiol 284: F338-F348, 2003
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, pp. F338-F348
-
-
Basile, D.P.1
Donohoe, D.L.2
Roethe, K.3
Mattson, D.L.4
-
38
-
-
4043077114
-
Rarefaction of peritubular capillaries following ischemic acute renal failure: A potential factor predisposing to progressive nephropathy
-
Basile DP: Rarefaction of peritubular capillaries following ischemic acute renal failure: A potential factor predisposing to progressive nephropathy. Curr Opin Nephrol Hypertens 13: 1-7, 2004
-
(2004)
Curr Opin Nephrol Hypertens
, vol.13
, pp. 1-7
-
-
Basile, D.P.1
-
39
-
-
33645673448
-
Acute-on-chronic renal failure in the rat: Functional compensation and hypoxia tolerance
-
Goldfarb M, Rosenberger C, Abassi Z, Shina A, Zilbersat F, Eckardt KU, Rosen S, Heyman SN: Acute-on-chronic renal failure in the rat: Functional compensation and hypoxia tolerance. Am J Nephrol 26: 22-33, 2006
-
(2006)
Am J Nephrol
, vol.26
, pp. 22-33
-
-
Goldfarb, M.1
Rosenberger, C.2
Abassi, Z.3
Shina, A.4
Zilbersat, F.5
Eckardt, K.U.6
Rosen, S.7
Heyman, S.N.8
-
40
-
-
84900525558
-
Renal oxygenation in acute renal ischemia-reperfusion injury
-
Abdelkader A, Ho J, Ow CP, Eppel GA, Rajapakse NW, Schlaich MP, Evans RG: Renal oxygenation in acute renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 306: F1026-F1038, 2014
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F1026-F1038
-
-
Abdelkader, A.1
Ho, J.2
Ow, C.P.3
Eppel, G.A.4
Rajapakse, N.W.5
Schlaich, M.P.6
Evans, R.G.7
-
41
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, Roth PH, Fang HM, Wang GL: Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269: 23757-23763, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
42
-
-
84866601479
-
Regulation of metabolism by hypoxia-inducible factor 1
-
Semenza GL: Regulation of metabolism by hypoxia-inducible factor 1. Cold Spring Harb Symp Quant Biol 76: 347-353, 2011
-
(2011)
Cold Spring Harb Symp Quant Biol
, vol.76
, pp. 347-353
-
-
Semenza, G.L.1
-
43
-
-
67349248855
-
Monitoring phosphorylation of the pyruvate dehydrogenase complex
-
Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon JE: Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem 389: 157-164, 2009
-
(2009)
Anal Biochem
, vol.389
, pp. 157-164
-
-
Rardin, M.J.1
Wiley, S.E.2
Naviaux, R.K.3
Murphy, A.N.4
Dixon, J.E.5
-
44
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV: HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3: 177-185, 2006
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
45
-
-
57649130593
-
Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance
-
Lu CW, Lin SC, Chen KF, Lai YY, Tsai SJ: Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance. J BiolChem283: 28106-28114, 2008
-
(2008)
J BiolChem
, vol.283
, pp. 28106-28114
-
-
Lu, C.W.1
Lin, S.C.2
Chen, K.F.3
Lai, Y.Y.4
Tsai, S.J.5
-
46
-
-
0022052810
-
Lactate production in isolated segments of the rat nephron
-
Bagnasco S,Good D, Balaban R, BurgM: Lactate production in isolated segments of the rat nephron. Am J Physiol 248: F522-F526, 1985
-
(1985)
Am J Physiol
, vol.248
, pp. F522-F526
-
-
Bagnasco, S.1
Good, D.2
Balaban, R.3
Burg, M.4
-
47
-
-
0021356212
-
Hormonal regulation of hepatic gluconeogenesis
-
Kraus-Friedmann N: Hormonal regulation of hepatic gluconeogenesis. Physiol Rev 64: 170-259, 1984
-
(1984)
Physiol Rev
, vol.64
, pp. 170-259
-
-
Kraus-Friedmann, N.1
-
48
-
-
0037155247
-
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in theWarburg effect
-
MinchenkoA,Leshchinsky I,Opentanova I, SangN, SrinivasV,ArmsteadV, Caro J: Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in theWarburg effect. J Biol Chem 277: 6183-6187, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 6183-6187
-
-
Minchenko, A.1
Leshchinsky, I.2
Opentanova, I.3
Sang, N.4
Srinivas, V.5
Armstead, V.6
Caro, J.7
-
49
-
-
0033057367
-
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect
-
Chesney J, Mitchell R, Benigni F, Bacher M, Spiegel L, Al-Abed Y, Han JH, Metz C, Bucala R: An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect. Proc Natl Acad Sci U S A 96: 3047-3052, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3047-3052
-
-
Chesney, J.1
Mitchell, R.2
Benigni, F.3
Bacher, M.4
Spiegel, L.5
Al-Abed, Y.6
Han, J.H.7
Metz, C.8
Bucala, R.9
-
50
-
-
0030741726
-
Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase
-
Sakakibara R, Kato M, Okamura N, Nakagawa T, Komada Y, Tominaga N, Shimojo M, Fukasawa M: Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase. J Biochem 122: 122-128, 1997
-
(1997)
J Biochem
, vol.122
, pp. 122-128
-
-
Sakakibara, R.1
Kato, M.2
Okamura, N.3
Nakagawa, T.4
Komada, Y.5
Tominaga, N.6
Shimojo, M.7
Fukasawa, M.8
-
51
-
-
14044257274
-
Transforming growth factorbeta in acute renal failure: Receptor expression, effects on proliferation, cellularity, and vascularization after recovery from injury
-
Spurgeon KR, Donohoe DL, Basile DP: Transforming growth factorbeta in acute renal failure: Receptor expression, effects on proliferation, cellularity, and vascularization after recovery from injury. Am J Physiol Renal Physiol 288: F568-F577, 2005
-
(2005)
Am J Physiol Renal Physiol
, vol.288
, pp. F568-F577
-
-
Spurgeon, K.R.1
Donohoe, D.L.2
Basile, D.P.3
-
52
-
-
84887056240
-
Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI
-
Fähling M, Mathia S, Paliege A, Koesters R, Mrowka R, Peters H, Persson PB, Neumayer HH, Bachmann S, Rosenberger C: Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI. J Am Soc Nephrol 24: 1806-1819, 2013
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1806-1819
-
-
Fähling, M.1
Mathia, S.2
Paliege, A.3
Koesters, R.4
Mrowka, R.5
Peters, H.6
Persson, P.B.7
Neumayer, H.H.8
Bachmann, S.9
Rosenberger, C.10
-
53
-
-
84862787119
-
Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
-
Chen J, Chen JK, Harris RC: Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury. Kidney Int 82: 45-52, 2012
-
(2012)
Kidney Int
, vol.82
, pp. 45-52
-
-
Chen, J.1
Chen, J.K.2
Harris, R.C.3
-
54
-
-
62649150345
-
The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology
-
Zeng F, Singh AB, Harris RC: The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology. Exp Cell Res 315: 602-610, 2009
-
(2009)
Exp Cell Res
, vol.315
, pp. 602-610
-
-
Zeng, F.1
Singh, A.B.2
Harris, R.C.3
-
55
-
-
84877015143
-
Role of epidermal growth factor receptor in acute and chronic kidney injury
-
Tang J, Liu N, Zhuang S: Role of epidermal growth factor receptor in acute and chronic kidney injury. Kidney Int 83: 804-810, 2013
-
(2013)
Kidney Int
, vol.83
, pp. 804-810
-
-
Tang, J.1
Liu, N.2
Zhuang, S.3
-
56
-
-
4143118768
-
Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration
-
Zhuang S, Dang Y, Schnellmann RG: Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration. Am J Physiol Renal Physiol 287: F365-F372, 2004
-
(2004)
Am J Physiol Renal Physiol
, vol.287
, pp. F365-F372
-
-
Zhuang, S.1
Dang, Y.2
Schnellmann, R.G.3
-
57
-
-
20444417067
-
P38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury
-
Zhuang S, Yan Y, Han J, Schnellmann RG: p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. J Biol Chem 280: 21036-21042, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 21036-21042
-
-
Zhuang, S.1
Yan, Y.2
Han, J.3
Schnellmann, R.G.4
-
58
-
-
42449141549
-
Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor
-
Hallman MA, Zhuang S, Schnellmann RG: Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. J Pharmacol Exp Ther 325: 520-528, 2008
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 520-528
-
-
Hallman, M.A.1
Zhuang, S.2
Schnellmann, R.G.3
-
59
-
-
0028785437
-
Integrative effects of EGF on metabolism and proliferation in renal proximal tubular cells
-
Nowak G, Schnellmann RG: Integrative effects of EGF on metabolism and proliferation in renal proximal tubular cells. Am J Physiol 269: C1317-C1325, 1995
-
(1995)
Am J Physiol
, vol.269
, pp. C1317-C1325
-
-
Nowak, G.1
Schnellmann, R.G.2
-
60
-
-
84863116842
-
EGFR signaling promotes TGFb-dependent renal fibrosis
-
Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC: EGFR signaling promotes TGFb-dependent renal fibrosis. J Am Soc Nephrol 23: 215-224, 2012
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 215-224
-
-
Chen, J.1
Chen, J.K.2
Nagai, K.3
Plieth, D.4
Tan, M.5
Lee, T.C.6
Threadgill, D.W.7
Neilson, E.G.8
Harris, R.C.9
-
61
-
-
20244383986
-
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor
-
Bonniaud P,Margetts PJ, KolbM, Schroeder JA, KapounAM,DammD, Murphy A, Chakravarty S, Dugar S, Higgins L, Protter AA, Gauldie J: Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am J Respir Crit Care Med 171: 889-898, 2005
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 889-898
-
-
Bonniaud, P.1
Margetts, P.J.2
Kolb, M.3
Schroeder, J.A.4
Kapoun, A.M.5
Damm, D.6
Murphy, A.7
Chakravarty, S.8
Dugar, S.9
Higgins, L.10
Protter, A.A.11
Gauldie, J.12
-
62
-
-
33746265817
-
Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression
-
Kapoun AM,GasparNJ, Wang Y, DammD, Liu YW, O'young G, Quon D, Lam A, Munson K, Tran TT, Ma JY, Murphy A, Dugar S, Chakravarty S, Protter AA, Wen FQ, Liu X, Rennard SI, Higgins LS: Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression. Mol Pharmacol 70: 518-531, 2006
-
(2006)
Mol Pharmacol
, vol.70
, pp. 518-531
-
-
Kapoun, A.M.1
Gaspar, N.J.2
Wang, Y.3
Damm, D.4
Liu, Y.W.5
O'Young, G.6
Quon, D.7
Lam, A.8
Munson, K.9
Tran, T.T.10
Ma, J.Y.11
Murphy, A.12
Dugar, S.13
Chakravarty, S.14
Protter, A.A.15
Wen, F.Q.16
Liu, X.17
Rennard, S.I.18
Higgins, L.S.19
-
63
-
-
0026047651
-
Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse
-
JatPS,NobleMD,AtaliotisP, TanakaY, YannoutsosN, LarsenL,KioussisD: Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A 88: 5096-5100, 1991
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 5096-5100
-
-
Jat, P.S.1
Noble, M.D.2
Ataliotis, P.3
Tanaka, Y.4
Yannoutsos, N.5
Larsen, L.6
Kioussis, D.7
-
64
-
-
0037370978
-
Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens
-
Sinha D,Wang Z, Price VR, Schwartz JH, LieberthalW: Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens. Am J Physiol Renal Physiol 284: F488-F497, 2003
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, pp. F488-F497
-
-
Sinha, D.1
Wang, Z.2
Price, V.R.3
Schwartz, J.H.4
Lieberthal, W.5
-
65
-
-
0016335085
-
Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy
-
McLean IW, Nakane PK: Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. J Histochem Cytochem 22: 1077-1083, 1974
-
(1974)
J Histochem Cytochem
, vol.22
, pp. 1077-1083
-
-
McLean, I.W.1
Nakane, P.K.2
|