Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis

Cell Metabolism

Volumn 24, Issue 5, 2016, Pages 753-761

  Sahu, Nisebita ^a   Dela Cruz, Darlene ^a   Gao, Min ^a   Sandoval, Wendy ^a   Haverty, Peter M ^a   Liu, Jinfeng ^a   Stephan, Jean Philippe ^a   Haley, Benjamin ^a   Classon, Marie ^a   Hatzivassiliou, Georgia ^a   Settleman, Jeff ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROLINE; CAPPED RNA; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PHOSPHOPROTEIN; TARGET OF RAPAMYCIN KINASE;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL LINE; CARCINOGENESIS; CLONOGENESIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH; ANIMAL; BIOSYNTHESIS; CELL CLONE; CELL LINE; CELL PROLIFERATION; DEFICIENCY; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS;

ANIMALS; CARCINOGENESIS; CELL LINE; CELL PROLIFERATION; CLONE CELLS; ENDOPLASMIC RETICULUM STRESS; MICE; MULTIPROTEIN COMPLEXES; PHOSPHOPROTEINS; PROLINE; PROTEIN BIOSYNTHESIS; RNA CAPS; TOR SERINE-THREONINE KINASES;

EID: 84994631171     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.08.008     Document Type: Article

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