Glutamine connections

Nature Reviews Cancer

Volumn 13, Issue 5, 2013, Pages 293-

  Burgess, Darren J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GLUCOSE; GLUTAMINE; GLUTATHIONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; K RAS PROTEIN; LACTIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; VON HIPPEL LINDAU PROTEIN;

ANAEROBIC GLYCOLYSIS; CANCER CELL; CELL STRAIN HCT116; CITRIC ACID CYCLE; CYTOTOXICITY; FIBROBLAST; HUMAN; HYPOXIC CELL; KIDNEY CARCINOMA; LOSS OF FUNCTION MUTATION; NONHUMAN; NOTE; OXIDATION REDUCTION STATE; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; SUPPRESSOR GENE; TUMOR XENOGRAFT;

EID: 84876836509     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc3515     Document Type: Note

References (3)

1. Gameiro, P. A., et al. In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation. Cell Metab. 17, 372-385 (2013)
2. Son, J., et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature 27 Mar 2013 (doi:10.1038/nature12040)
3. Reid, M. A., et al. The B55? subunit of PP2A drives a p53- dependent metabolic adaptation to glutamine deprivation. Mol. Cell 13 Mar 2013 (doi:10.1016/j. molcel.2013.02.008)