메뉴 건너뛰기




Volumn 110, Issue , 2017, Pages 19-23

Drug distribution in nanostructured lipid particles

Author keywords

Dermal drug delivery; Dexamethasone; Drug delivery system; Electron paramagnetic resonance (EPR) spectroscopy; Lipids; Nanoparticles; Spinlabel

Indexed keywords

DEXAMETHASONE; GELUCIRE; SOLID LIPID NANOPARTICLE; WATER; WITEPSOL; CAPRYOL PROPYLENE GLYCOL MONOCAPRYLATE; COLLOID; DRUG CARRIER; FAT; GELUCIRE 50-13; GLUCOCORTICOID; LIPID; NANOPARTICLE; OIL; POLYMER; PROPANEDIOL DERIVATIVE; SPIN LABEL; TRIACYLGLYCEROL;

EID: 84994589617     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2016.10.008     Document Type: Article
Times cited : (19)

References (37)
  • 1
    • 1542268930 scopus 로고    scopus 로고
    • Lipid vesicles and other colloids as drug carriers on the skin
    • [1] Cevc, G., Lipid vesicles and other colloids as drug carriers on the skin. Adv. Drug Deliv. Rev. 56:5 (2004), 675–711.
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , Issue.5 , pp. 675-711
    • Cevc, G.1
  • 2
    • 0042918919 scopus 로고
    • Solid lipid nanoparticles (SLN) – an alternative parenteral drug carrier system
    • [2] Lucks, J.S., Müller, R.H., König, B., Solid lipid nanoparticles (SLN) – an alternative parenteral drug carrier system. Eur. J. Pharm. Biopharm., 38, 1992, 33S.
    • (1992) Eur. J. Pharm. Biopharm. , vol.38 , pp. 33S
    • Lucks, J.S.1    Müller, R.H.2    König, B.3
  • 3
    • 0001469131 scopus 로고
    • Submicron-sized parenteral carrier systems based on solid lipids
    • [3] Siekmann, B., Westesen, K., Submicron-sized parenteral carrier systems based on solid lipids. Pharm. Pharmacol. Lett. 1 (1992), 123–126.
    • (1992) Pharm. Pharmacol. Lett. , vol.1 , pp. 123-126
    • Siekmann, B.1    Westesen, K.2
  • 4
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: production, characterization and applications
    • [4] Mäder, K., Mehnert, W., Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 47:2–3 (2001), 165–196.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , Issue.2-3 , pp. 165-196
    • Mäder, K.1    Mehnert, W.2
  • 5
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • [5] Müller, R.H., Radtke, M., Wissing, S.A., Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv. Drug Deliv. Rev. 54 (2002), 131–155.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 131-155
    • Müller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 6
    • 0028954379 scopus 로고
    • Solid lipid nanoparticles (SLN) – an alternative colloidal carrier system for controlled drug-delivery
    • [6] Müller, R.H., et al. Solid lipid nanoparticles (SLN) – an alternative colloidal carrier system for controlled drug-delivery. Eur. J. Pharm. Biopharm. 41:1 (1995), 62–69.
    • (1995) Eur. J. Pharm. Biopharm. , vol.41 , Issue.1 , pp. 62-69
    • Müller, R.H.1
  • 7
    • 57049140960 scopus 로고    scopus 로고
    • Entrapment and release of saquinavir using novel cationic solid lipid nanoparticles
    • [7] Kuo, Y.C., Chen, H.H., Entrapment and release of saquinavir using novel cationic solid lipid nanoparticles. Int. J. Pharm. 365:1–2 (2009), 206–213.
    • (2009) Int. J. Pharm. , vol.365 , Issue.1-2 , pp. 206-213
    • Kuo, Y.C.1    Chen, H.H.2
  • 8
    • 1242338847 scopus 로고    scopus 로고
    • Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
    • [8] Jores, K., et al. Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy. J. Control. Release 95:2 (2004), 217–227.
    • (2004) J. Control. Release , vol.95 , Issue.2 , pp. 217-227
    • Jores, K.1
  • 9
    • 33646106067 scopus 로고    scopus 로고
    • Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy
    • [9] Saupe, A., Gordon, K.C., Rades, T., Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy. Int. J. Pharm. 314:1 (2006), 56–62.
    • (2006) Int. J. Pharm. , vol.314 , Issue.1 , pp. 56-62
    • Saupe, A.1    Gordon, K.C.2    Rades, T.3
  • 10
    • 0030866983 scopus 로고    scopus 로고
    • Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential
    • [10] Westesen, K., Bunjes, H., Koch, M.H.J., Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential. J. Control. Release 48:2–3 (1997), 223–236.
    • (1997) J. Control. Release , vol.48 , Issue.2-3 , pp. 223-236
    • Westesen, K.1    Bunjes, H.2    Koch, M.H.J.3
  • 11
    • 0042125467 scopus 로고    scopus 로고
    • Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study
    • [11] Jores, K., Mehnert, W., Mäder, K., Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study. Pharm. Res. 20:8 (2003), 1274–1283.
    • (2003) Pharm. Res. , vol.20 , Issue.8 , pp. 1274-1283
    • Jores, K.1    Mehnert, W.2    Mäder, K.3
  • 12
    • 28244474457 scopus 로고    scopus 로고
    • Lipid nanoparticles for skin penetration enhancement – correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy
    • [12] Lombardi Borgia, S., et al. Lipid nanoparticles for skin penetration enhancement – correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J. Control. Release 110:1 (2005), 151–163.
    • (2005) J. Control. Release , vol.110 , Issue.1 , pp. 151-163
    • Lombardi Borgia, S.1
  • 13
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art
    • [13] Müller, R.H., Mäder, K., Gohla, S., Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur. J. Pharm. Biopharm. 50:1 (2000), 161–177.
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , Issue.1 , pp. 161-177
    • Müller, R.H.1    Mäder, K.2    Gohla, S.3
  • 14
    • 57849099131 scopus 로고    scopus 로고
    • Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
    • [14] Pardeike, J., Hommoss, A., Müller, R.H., Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int. J. Pharm. 366:1–2 (2009), 170–184.
    • (2009) Int. J. Pharm. , vol.366 , Issue.1-2 , pp. 170-184
    • Pardeike, J.1    Hommoss, A.2    Müller, R.H.3
  • 15
    • 84900894493 scopus 로고    scopus 로고
    • Impact of lipid dynamic behavior on physical stability, in vitro release and skin permeation of genistein-loaded lipid nanoparticles
    • [15] Andrade, L.M., et al. Impact of lipid dynamic behavior on physical stability, in vitro release and skin permeation of genistein-loaded lipid nanoparticles. Eur. J. Pharm. Biopharm. 88 (2014), 40–47.
    • (2014) Eur. J. Pharm. Biopharm. , vol.88 , pp. 40-47
    • Andrade, L.M.1
  • 16
    • 34547905035 scopus 로고    scopus 로고
    • Lipid nanoparticles for improved topical application of drugs for skin diseases
    • [16] Schäfer-Korting, M., Mehnert, W., Korting, H.C., Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv. Drug Deliv. Rev. 59 (2007), 427–443.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 427-443
    • Schäfer-Korting, M.1    Mehnert, W.2    Korting, H.C.3
  • 17
    • 84923845158 scopus 로고    scopus 로고
    • Corticosteroids in Stevens-Johnson Syndrome/toxic epidermal necrolysis: current evidence and implications for future research
    • [17] Law, E.H., Leung, M., Corticosteroids in Stevens-Johnson Syndrome/toxic epidermal necrolysis: current evidence and implications for future research. Ann. Pharmacother. 49:3 (2015), 335–342.
    • (2015) Ann. Pharmacother. , vol.49 , Issue.3 , pp. 335-342
    • Law, E.H.1    Leung, M.2
  • 18
    • 0034933792 scopus 로고    scopus 로고
    • Polarity and permeation profiles in lipid membranes
    • [18] Marsh, D., Polarity and permeation profiles in lipid membranes. Proc. Natl. Acad. Sci. U.S.A. 98:14 (2001), 7777–7782.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , Issue.14 , pp. 7777-7782
    • Marsh, D.1
  • 19
    • 0028281769 scopus 로고
    • 250-GHz electron spin resonance studies of polarity gradients along the aliphatic chains in phospholipid membranes
    • [19] Earle, K.A., et al. 250-GHz electron spin resonance studies of polarity gradients along the aliphatic chains in phospholipid membranes. Biophys. J. 66:4 (1994), 1213–1221.
    • (1994) Biophys. J. , vol.66 , Issue.4 , pp. 1213-1221
    • Earle, K.A.1
  • 20
    • 0028108981 scopus 로고
    • Investigation of structure and dynamics in membrane proteins using site-directed spin labeling
    • [20] Hubbell, W.L., Altenbach, C., Investigation of structure and dynamics in membrane proteins using site-directed spin labeling. Curr. Opin. Struct. Biol. 4 (1994), 566–573.
    • (1994) Curr. Opin. Struct. Biol. , vol.4 , pp. 566-573
    • Hubbell, W.L.1    Altenbach, C.2
  • 21
    • 0034639884 scopus 로고    scopus 로고
    • High-field EPR studies of the structure and conformational changes of site-directed spin labeled bacteriorhodopsin
    • [21] Steinhoff, H.-J., et al. High-field EPR studies of the structure and conformational changes of site-directed spin labeled bacteriorhodopsin. Biochim. Biophys. Acta – Bioenergetics 1457:3 (2000), 253–262.
    • (2000) Biochim. Biophys. Acta – Bioenergetics , vol.1457 , Issue.3 , pp. 253-262
    • Steinhoff, H.-J.1
  • 22
    • 79961122904 scopus 로고    scopus 로고
    • Stabilization of reactive nitroxides using invasomes to allow prolonged electron paramagnetic resonance measurements
    • [22] Haag, S.F., et al. Stabilization of reactive nitroxides using invasomes to allow prolonged electron paramagnetic resonance measurements. Skin Pharmacol. Physiol. 24:6 (2011), 312–321.
    • (2011) Skin Pharmacol. Physiol. , vol.24 , Issue.6 , pp. 312-321
    • Haag, S.F.1
  • 23
    • 0034657061 scopus 로고    scopus 로고
    • In vivo EPR of topical delivery of a hydrophilic substance encapsulated in multilamellar liposomes applied to the skin of hairless and normal mice
    • [23] Honzak, L., Sentjurc, M., Swartz, H.M., In vivo EPR of topical delivery of a hydrophilic substance encapsulated in multilamellar liposomes applied to the skin of hairless and normal mice. J. Control. Release 66:2–3 (2000), 221–228.
    • (2000) J. Control. Release , vol.66 , Issue.2-3 , pp. 221-228
    • Honzak, L.1    Sentjurc, M.2    Swartz, H.M.3
  • 24
    • 34147168177 scopus 로고    scopus 로고
    • Interaction of drug molecules with carrier systems as studied by parelectric spectroscopy and electron spin resonance
    • [24] Braem, C., et al. Interaction of drug molecules with carrier systems as studied by parelectric spectroscopy and electron spin resonance. J. Control. Release: Off. J. Control. Release Soc. 119:1 (2007), 128–135.
    • (2007) J. Control. Release: Off. J. Control. Release Soc. , vol.119 , Issue.1 , pp. 128-135
    • Braem, C.1
  • 25
    • 80051793071 scopus 로고    scopus 로고
    • Skin penetration enhancement of core-multishell nanotransporters and invasomes measured by electron paramagnetic resonance spectroscopy
    • [25] Haag, S.F., et al. Skin penetration enhancement of core-multishell nanotransporters and invasomes measured by electron paramagnetic resonance spectroscopy. Int. J. Pharm. 416:1 (2011), 223–228.
    • (2011) Int. J. Pharm. , vol.416 , Issue.1 , pp. 223-228
    • Haag, S.F.1
  • 26
    • 72149125040 scopus 로고    scopus 로고
    • Application of Electron Paramagnetic Resonance (EPR) spectroscopy and imaging in drug delivery research – chances and challenges
    • [26] Kempe, S., Metz, H., Mäder, K., Application of Electron Paramagnetic Resonance (EPR) spectroscopy and imaging in drug delivery research – chances and challenges. Eur. J. Pharm. Biopharm. 74:1 (2010), 55–66.
    • (2010) Eur. J. Pharm. Biopharm. , vol.74 , Issue.1 , pp. 55-66
    • Kempe, S.1    Metz, H.2    Mäder, K.3
  • 27
    • 84994650647 scopus 로고    scopus 로고
    • Spin-labelled dexamethasone for Electron-Paramagnetic Resonance (EPR) Spectroscopy, (in preparation).
    • [27] M.L. Unbehauen, et al., Spin-labelled dexamethasone for Electron-Paramagnetic Resonance (EPR) Spectroscopy, 2016 (in preparation).
    • (2016)
    • Unbehauen, M.L.1
  • 29
    • 28844486080 scopus 로고    scopus 로고
    • EasySpin, a comprehensive software package for spectral simulation and analysis in EPR
    • [29] Stoll, S., Schweiger, A., EasySpin, a comprehensive software package for spectral simulation and analysis in EPR. J. Magn. Reson. 178:1 (2006), 42–55.
    • (2006) J. Magn. Reson. , vol.178 , Issue.1 , pp. 42-55
    • Stoll, S.1    Schweiger, A.2
  • 30
    • 0000717350 scopus 로고
    • Solvent effects on the g-value of di-t-butyl nitric oxide
    • [30] Kawamura, T., Matsunami, S., Yonezawa, T., Solvent effects on the g-value of di-t-butyl nitric oxide. Bull. Chem. Soc. Jpn. 40:5 (1967), 1111–1115.
    • (1967) Bull. Chem. Soc. Jpn. , vol.40 , Issue.5 , pp. 1111-1115
    • Kawamura, T.1    Matsunami, S.2    Yonezawa, T.3
  • 31
    • 0035857235 scopus 로고    scopus 로고
    • Influence of solvent polarity and hydrogen bonding on the EPR parameters of nitroxide spin label studied by 9-GHz and 95-GHz EPR spectroscopy and DFT calculations
    • [31] Owenius, R., et al. Influence of solvent polarity and hydrogen bonding on the EPR parameters of nitroxide spin label studied by 9-GHz and 95-GHz EPR spectroscopy and DFT calculations. J. Phys. Chem. 105:49 (2001), 10967–10977.
    • (2001) J. Phys. Chem. , vol.105 , Issue.49 , pp. 10967-10977
    • Owenius, R.1
  • 32
    • 71149120560 scopus 로고    scopus 로고
    • Spin-label EPR for determining polarity and proticity in biomolecular assemblies: transmembrane profiles
    • [32] Marsh, D., Spin-label EPR for determining polarity and proticity in biomolecular assemblies: transmembrane profiles. Appl. Magn. Reson. 37:1–4 (2010), 435–454.
    • (2010) Appl. Magn. Reson. , vol.37 , Issue.1-4 , pp. 435-454
    • Marsh, D.1
  • 33
    • 32144463825 scopus 로고    scopus 로고
    • Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery
    • [33] Kim, D.H., Martin, D.C., Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery. Biomaterials 27:15 (2006), 3031–3037.
    • (2006) Biomaterials , vol.27 , Issue.15 , pp. 3031-3037
    • Kim, D.H.1    Martin, D.C.2
  • 34
    • 85006088626 scopus 로고    scopus 로고
    • Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multifrequency electron paramagnetic resonance (EPR) spectroscopy
    • [34] Saeidpour, S., et al. Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multifrequency electron paramagnetic resonance (EPR) spectroscopy. Eur. J. Pharm. Biopharm., 2006, 10.1016/j.ejpb.2016.10.001.
    • (2006) Eur. J. Pharm. Biopharm.
    • Saeidpour, S.1
  • 35
    • 0002844265 scopus 로고
    • Theory of slow tumbling ESR spectra for nitroxides
    • L.J. Berliner Academic Press Inc.
    • [35] Freed, J.H., Theory of slow tumbling ESR spectra for nitroxides. Berliner, L.J., (eds.) Spin Labeling Theory and Application, 1976, Academic Press Inc.
    • (1976) Spin Labeling Theory and Application
    • Freed, J.H.1
  • 36
    • 3042593645 scopus 로고    scopus 로고
    • Glucocorticoid entrapment into lipid carriers–characterisation by parelectric spectroscopy and influence on dermal uptake
    • [36] Sivaramakrishnan, R., et al. Glucocorticoid entrapment into lipid carriers–characterisation by parelectric spectroscopy and influence on dermal uptake. J. Control. Release 97:3 (2004), 493–502.
    • (2004) J. Control. Release , vol.97 , Issue.3 , pp. 493-502
    • Sivaramakrishnan, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.