메뉴 건너뛰기




Volumn 22, Issue 21, 2016, Pages 5183-5188

Molecular pathways: Targeting CD96 and TIGIT for cancer immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

CD96 ANTIBODY; CD96 PROTEIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; LYMPHOCYTE RECEPTOR; MONOCLONAL ANTIBODY; PD 1 ANTIBODY; TIGIT PROTEIN; UNCLASSIFIED DRUG; CD96 ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN;

EID: 84994559614     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-0933     Document Type: Article
Times cited : (182)

References (51)
  • 1
    • 84931083080 scopus 로고    scopus 로고
    • Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (Check mate 037): A randomised, controlled, open-label, phase 3 trial
    • Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (Check Mate 037): A randomised, controlled, open-label, phase 3 trial. Lancet Oncol 2015; 16:375-84.
    • (2015) Lancet Oncol , vol.16 , pp. 375-384
    • Weber, J.S.1    D'Angelo, S.P.2    Minor, D.3    Hodi, F.S.4    Gutzmer, R.5    Neyns, B.6
  • 2
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363:711-23.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1
  • 5
    • 84934441505 scopus 로고    scopus 로고
    • Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: The force awakens
    • Childs RW, Carlsten M. Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: The force awakens. Nat Rev Drug Discov 2015;14:487-98.
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 487-498
    • Childs, R.W.1    Carlsten, M.2
  • 7
    • 84925488589 scopus 로고    scopus 로고
    • Nectin family of cell-adhesion molecules: Structural and molecular aspects of function and specificity
    • Samanta D, Almo SC. Nectin family of cell-adhesion molecules: Structural and molecular aspects of function and specificity. Cell Mol Life Sci 2015;72:645-58.
    • (2015) Cell Mol Life Sci , vol.72 , pp. 645-658
    • Samanta, D.1    Almo, S.C.2
  • 8
    • 84925743331 scopus 로고    scopus 로고
    • Balancing natural killer cell activation through paired receptors
    • Martinet L, Smyth MJ. Balancing natural killer cell activation through paired receptors. Nat Rev Immunol 2015;15:243-54.
    • (2015) Nat Rev Immunol , vol.15 , pp. 243-254
    • Martinet, L.1    Smyth, M.J.2
  • 10
    • 36849075789 scopus 로고    scopus 로고
    • The CD155/poliovirus receptor enhances the proliferation of ras-mutated cells
    • Kono T, Imai Y, Yasuda S, Ohmori K, Fukui H, Ichikawa K, et al. The CD155/poliovirus receptor enhances the proliferation of ras-mutated cells. Int J Cancer 2008;122:317-24.
    • (2008) Int J Cancer , vol.122 , pp. 317-324
    • Kono, T.1    Imai, Y.2    Yasuda, S.3    Ohmori, K.4    Fukui, H.5    Ichikawa, K.6
  • 12
    • 84929000784 scopus 로고    scopus 로고
    • TIGIT and PD-1 impair tumor antigen-specific CD8+ T cells in melanoma patients
    • Chauvin JM, Pagliano O, Fourcade J, Sun Z, Wang H, Sander C, et al. TIGIT and PD-1 impair tumor antigen-specific CD8+ T cells in melanoma patients. J Clin Invest 2015;125:2046-58.
    • (2015) J Clin Invest , vol.125 , pp. 2046-2058
    • Chauvin, J.M.1    Pagliano, O.2    Fourcade, J.3    Sun, Z.4    Wang, H.5    Sander, C.6
  • 13
    • 66449134616 scopus 로고    scopus 로고
    • NCRs and DNAM-1mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
    • Lakshmikanth T, Burke S, Ali TH, Kimpfler S, Ursini F, Ruggeri L, et al. NCRs and DNAM-1mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J Clin Invest 2009; 119:1251-63.
    • (2009) J Clin Invest , vol.119 , pp. 1251-1263
    • Lakshmikanth, T.1    Burke, S.2    Ali, T.H.3    Kimpfler, S.4    Ursini, F.5    Ruggeri, L.6
  • 17
    • 15844375309 scopus 로고    scopus 로고
    • DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes
    • Shibuya A, Campbell D, Hannum C, Yssel H, Franz-Bacon K, McClanahan T, et al. DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity 1996;4:573-81.
    • (1996) Immunity , vol.4 , pp. 573-581
    • Shibuya, A.1    Campbell, D.2    Hannum, C.3    Yssel, H.4    Franz-Bacon, K.5    McClanahan, T.6
  • 18
    • 84975077054 scopus 로고    scopus 로고
    • T-cell immunoglobulin and ITIM domain (TIGIT) associates with CD8+ T-cell exhaustion and poor clinical outcome in AML patients
    • Kong Y, Zhu L, Schell TD, Zhang J, Claxton DF, Ehmann WC, et al. T-cell immunoglobulin and ITIM Domain (TIGIT) associates with CD8+ T-cell exhaustion and poor clinical outcome in AML patients. Clin Cancer Res 2016;22:3057-66.
    • (2016) Clin Cancer Res , vol.22 , pp. 3057-3066
    • Kong, Y.1    Zhu, L.2    Schell, T.D.3    Zhang, J.4    Claxton, D.F.5    Ehmann, W.C.6
  • 20
    • 59649095271 scopus 로고    scopus 로고
    • DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors
    • Gilfillan S, Chan CJ, Cella M, Haynes NM, Rapaport AS, Boles KS, et al. DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors. J Exp Med 2008;205: 2965-73.
    • (2008) J Exp Med , vol.205 , pp. 2965-2973
    • Gilfillan, S.1    Chan, C.J.2    Cella, M.3    Haynes, N.M.4    Rapaport, A.S.5    Boles, K.S.6
  • 21
    • 84919494669 scopus 로고    scopus 로고
    • The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function
    • Johnston RJ, Comps-Agrar L, Hackney J, Yu X, Huseni M, Yang Y, et al. The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function. Cancer Cell 2014;26:923-37.
    • (2014) Cancer Cell , vol.26 , pp. 923-937
    • Johnston, R.J.1    Comps-Agrar, L.2    Hackney, J.3    Yu, X.4    Huseni, M.5    Yang, Y.6
  • 22
    • 84956803081 scopus 로고    scopus 로고
    • TIGIT marks exhausted T cells, correlates with disease progression, and serves as a target for immune restoration in HIV and SIV infection
    • Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, et al. TIGIT marks exhausted T cells, correlates with disease progression, and serves as a target for immune restoration in HIV and SIV infection. PLoS Pathog 2016;12:e1005349.
    • (2016) PLoS Pathog , vol.12 , pp. e1005349
    • Chew, G.M.1    Fujita, T.2    Webb, G.M.3    Burwitz, B.J.4    Wu, H.L.5    Reed, J.S.6
  • 24
    • 0042922822 scopus 로고    scopus 로고
    • Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule
    • Bottino C, Castriconi R, Pende D, Rivera P, Nanni M, Carnemolla B, et al. Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med 2003;198:557-67.
    • (2003) J Exp Med , vol.198 , pp. 557-567
    • Bottino, C.1    Castriconi, R.2    Pende, D.3    Rivera, P.4    Nanni, M.5    Carnemolla, B.6
  • 25
    • 57849101994 scopus 로고    scopus 로고
    • The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
    • Yu X, Harden K, Gonzalez LC, Francesco M, Chiang E, Irving B, et al. The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nat Immunol 2009;10:48-57.
    • (2009) Nat Immunol , vol.10 , pp. 48-57
    • Yu, X.1    Harden, K.2    Gonzalez, L.C.3    Francesco, M.4    Chiang, E.5    Irving, B.6
  • 26
    • 0026566333 scopus 로고
    • Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily
    • Wang PL, O'Farrell S, Clayberger C, Krensky AM. Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily. J Immunol 1992;148:2600-8.
    • (1992) J Immunol , vol.148 , pp. 2600-2608
    • Wang, P.L.1    O'Farrell, S.2    Clayberger, C.3    Krensky, A.M.4
  • 27
    • 84893100346 scopus 로고    scopus 로고
    • Investigating cell surface markers on normal hematopoietic stem cells in three different niche conditions
    • Garg S, Madkaikar M, Ghosh K. Investigating cell surface markers on normal hematopoietic stem cells in three different niche conditions. Int J Stem Cells 2013;6:129-33.
    • (2013) Int J Stem Cells , vol.6 , pp. 129-133
    • Garg, S.1    Madkaikar, M.2    Ghosh, K.3
  • 28
    • 67649966533 scopus 로고    scopus 로고
    • DNAX accessory molecule-1 (CD226) promotes human hepatocellular carcinoma cell lysis by vgamma9vdelta2 T cells
    • Toutirais O, Cabillic F, Le Friec G, Salot S, Loyer P, Le Gallo M, et al. DNAX accessory molecule-1 (CD226) promotes human hepatocellular carcinoma cell lysis by Vgamma9Vdelta2 T cells. Eur J Immunol 2009;39:1361-8.
    • (2009) Eur J Immunol , vol.39 , pp. 1361-1368
    • Toutirais, O.1    Cabillic, F.2    Le Friec, G.3    Salot, S.4    Loyer, P.5    Le Gallo, M.6
  • 29
    • 59049083508 scopus 로고    scopus 로고
    • CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains
    • Meyer D, Seth S, Albrecht J, Maier MK, du Pasquier L, Ravens I, et al. CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains. J Biol Chem 2009;284:2235-44.
    • (2009) J Biol Chem , vol.284 , pp. 2235-2244
    • Meyer, D.1    Seth, S.2    Albrecht, J.3    Maier, M.K.4    Du Pasquier, L.5    Ravens, I.6
  • 31
    • 1642394991 scopus 로고    scopus 로고
    • Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155)
    • Fuchs A, Cella M, Giurisato E, Shaw AS, Colonna M. Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol 2004;172:3994-8.
    • (2004) J Immunol , vol.172 , pp. 3994-3998
    • Fuchs, A.1    Cella, M.2    Giurisato, E.3    Shaw, A.S.4    Colonna, M.5
  • 33
    • 84948390730 scopus 로고    scopus 로고
    • Expressions of CD96 and CD123 in bone marrow cells of patients with myelodysplastic syndromes
    • Zhang W, Shao Z, Fu R, Wang H, Li L, Liu H. Expressions of CD96 and CD123 in bone marrow cells of patients with myelodysplastic syndromes. Clin Lab 2015;61:1429-34.
    • (2015) Clin Lab , vol.61 , pp. 1429-1434
    • Zhang, W.1    Shao, Z.2    Fu, R.3    Wang, H.4    Li, L.5    Liu, H.6
  • 34
    • 11244332609 scopus 로고    scopus 로고
    • Intracellular signaling by the killer immunoglobulin-like receptors and Ly49
    • McVicar DW, Burshtyn DN. Intracellular signaling by the killer immunoglobulin-like receptors and Ly49. Sci STKE 2001;2001:re1.
    • (2001) Sci STKE , vol.2001 , pp. re1
    • McVicar, D.W.1    Burshtyn, D.N.2
  • 35
    • 84962449276 scopus 로고    scopus 로고
    • Suppression of metastases using a new lymphocyte checkpoint target for cancer immunotherapy
    • Blake SJ, Stannard K, Liu J, Allen S, Yong MC, Mittal D, et al. Suppression of metastases using a new lymphocyte checkpoint target for cancer immunotherapy. Cancer Discov 2016;6:446-59.
    • (2016) Cancer Discov , vol.6 , pp. 446-459
    • Blake, S.J.1    Stannard, K.2    Liu, J.3    Allen, S.4    Yong, M.C.5    Mittal, D.6
  • 36
    • 84878936788 scopus 로고    scopus 로고
    • Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells
    • Selby MJ, Engelhardt JJ, Quigley M, Henning KA, Chen T, Srinivasan M, et al. Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells. Cancer Immunol Res 2013;1:32-42.
    • (2013) Cancer Immunol Res , vol.1 , pp. 32-42
    • Selby, M.J.1    Engelhardt, J.J.2    Quigley, M.3    Henning, K.A.4    Chen, T.5    Srinivasan, M.6
  • 37
    • 84859468877 scopus 로고    scopus 로고
    • Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signalingmechanism that requires cis-trans receptor clustering
    • Stengel KF, Harden-Bowles K, Yu X, Rouge L, Yin J, Comps-Agrar L, et al. Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signalingmechanism that requires cis-trans receptor clustering. Proc Natl Acad Sci U S A 2012;109:5399-404.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5399-5404
    • Stengel, K.F.1    Harden-Bowles, K.2    Yu, X.3    Rouge, L.4    Yin, J.5    Comps-Agrar, L.6
  • 40
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupuslike autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupuslike autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999;11:141-51.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 43
    • 84960158903 scopus 로고    scopus 로고
    • Melanoma cells control antimelanoma CTL responses via interaction between TIGIT and CD155 in the effector phase
    • Inozume T, Yaguchi T, Furuta J, Harada K, Kawakami Y, Shimada S. Melanoma cells control antimelanoma CTL responses via interaction between TIGIT and CD155 in the effector phase. J Invest Dermatol 2016;136:255-63.
    • (2016) J Invest Dermatol , vol.136 , pp. 255-263
    • Inozume, T.1    Yaguchi, T.2    Furuta, J.3    Harada, K.4    Kawakami, Y.5    Shimada, S.6
  • 44
    • 84871290531 scopus 로고    scopus 로고
    • Differential expression of CD96 surface molecule represents CD8(+) T cells with dissimilar effector function during HIV-1 infection
    • Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF. Differential expression of CD96 surface molecule represents CD8(+) T cells with dissimilar effector function during HIV-1 infection. PLoS One 2012;7: e51696.
    • (2012) PLoS One , vol.7 , pp. e51696
    • Eriksson, E.M.1    Keh, C.E.2    Deeks, S.G.3    Martin, J.N.4    Hecht, F.M.5    Nixon, D.F.6
  • 45
    • 58149289788 scopus 로고    scopus 로고
    • Establishment of an enzyme-linked immunosorbent assay systemfor determining soluble CD96 and its application in the measurement of sCD96 in patients with viral hepatitis B and hepatic cirrhosis
    • Gong J, Zhu C, Zhuang R, Song C, Li Q, Xu Z, et al. Establishment of an enzyme-linked immunosorbent assay systemfor determining soluble CD96 and its application in the measurement of sCD96 in patients with viral hepatitis B and hepatic cirrhosis. Clin Exp Immunol 2009;155:207-15.
    • (2009) Clin Exp Immunol , vol.155 , pp. 207-215
    • Gong, J.1    Zhu, C.2    Zhuang, R.3    Song, C.4    Li, Q.5    Xu, Z.6
  • 46
    • 84873726325 scopus 로고    scopus 로고
    • Recruitment of grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells
    • Liu S, Zhang H, Li M, Hu D, Li C, Ge B, et al. Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells. Cell Death Differ 2013;20:456-64.
    • (2013) Cell Death Differ , vol.20 , pp. 456-464
    • Liu, S.1    Zhang, H.2    Li, M.3    Hu, D.4    Li, C.5    Ge, B.6
  • 48
    • 80655149467 scopus 로고    scopus 로고
    • Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells
    • Seth S, Qiu Q, Danisch S, Maier MK, Braun A, Ravens I, et al. Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells. J Biol Chem 2011;286:39153-63.
    • (2011) J Biol Chem , vol.286 , pp. 39153-39163
    • Seth, S.1    Qiu, Q.2    Danisch, S.3    Maier, M.K.4    Braun, A.5    Ravens, I.6
  • 51
    • 84898681799 scopus 로고    scopus 로고
    • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
    • Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, et al. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity 2014;40:569-81.
    • (2014) Immunity , vol.40 , pp. 569-581
    • Joller, N.1    Lozano, E.2    Burkett, P.R.3    Patel, B.4    Xiao, S.5    Zhu, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.