Interleukin-6 receptor-alpha signaling drives anti-RBC alloantibody production and t-follicular helper cell differentiation in a murine model of red blood cell alloimmunization

Haematologica

Volumn 101, Issue 11, 2016, Pages e440-e444

  Arneja, Abhinav ^a   Salazar, Juan E ^a   Jiang, Wenyu ^b   Hendrickson, Jeanne E ^c   Zimring, James C ^d   Luckey, Chance John ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c YALE UNIVERSITY   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

IL 6R expression; RBC alloimmunization; T follicular helper cell differentiation

Indexed keywords

ALLOANTIBODY; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 5; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN-6 RECEPTOR ALPHA;

ALLOIMMUNIZATION; ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; ERYTHROCYTE TRANSFUSION; HELPER CELL; LETTER; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; ERYTHROCYTE; IMMUNOLOGY; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; ERYTHROCYTES; ISOANTIBODIES; MICE; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84994553265     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2016.149278     Document Type: Letter

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