Role of NF-κB activation and Th1/Th2 imbalance in pulmonary toxicity induced by nano NiO

Environmental Toxicology

Volumn 32, Issue 4, 2017, Pages 1354-1362

  Chang, Xuhong ^a   Zhu, An ^a   Liu, Fangfang ^a   Zou, Lingyue ^a   Su, Li ^a   Li, Sheng ^b   Sun, Yingbiao ^a  

^a LANZHOU UNIVERSITY   (China)

^b LanZhou Center for Disease Control and Prevention   (China)

Author keywords

nanoparticle; NF B; nickel oxide; pulmonary toxicity; Th1 Th2

Indexed keywords

BIOLOGICAL ORGANS; CHEMICAL ACTIVATION; ENZYMES; NANOPARTICLES; NANOSENSORS; NICKEL; PROTEINS; TISSUE; TOXICITY;

EVALUATION INDICATORS; INFLAMMATORY CYTOKINES; INFLAMMATORY RESPONSE; INTRATRACHEAL INSTILLATION; NICKEL OXIDES (NIO); NUCLEAR FACTOR KAPPAB; PULMONARY TOXICITY; TH1/TH2;

NICKEL OXIDE;

CXCL3 CHEMOKINE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 2; GAMMA INTERFERON; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 8; MESSENGER RNA; NICKEL NANOPARTICLE; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; METAL NANOPARTICLE; NICKEL; NICKEL MONOXIDE; POLLUTANT;

CELLS AND CELL COMPONENTS; ELECTRODE; GENE EXPRESSION; INDUCED RESPONSE; INHIBITOR; INORGANIC COMPOUND; NANOPARTICLE; NANOTECHNOLOGY; PROTEIN; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IN VITRO STUDY; LUNG INJURY; LUNG PARENCHYMA; LUNG TOXICITY; MALE; NITRATIVE STRESS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; TH1 TH2 BALANCE; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; POLLUTANT; TH1 CELL; TH2 CELL; TOXICITY; TRANSCRIPTION INITIATION; WISTAR RAT;

RATTUS NORVEGICUS;

ANIMALS; CYTOKINES; ENVIRONMENTAL POLLUTANTS; GATA3 TRANSCRIPTION FACTOR; LUNG; LUNG INJURY; MALE; METAL NANOPARTICLES; NF-KAPPA B; NICKEL; RATS; RATS, WISTAR; TH1 CELLS; TH2 CELLS; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84994525198     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22329     Document Type: Article

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