ICU-Acquired Weakness

Chest

Volumn 150, Issue 5, 2016, Pages 1129-1140

  Jolley, Sarah E ^a   Bunnell, Aaron E ^b   Hough, Catherine L ^c  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

critical illness myopathy; critical illness polyneuropathy; ICU neuromuscular dysfunction; ICU rehabilitation; ICU acquired weakness

Indexed keywords

ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN; SEROTONIN 2C AGONIST;

ARTIFICIAL VENTILATION; CLINICAL TRIAL (TOPIC); CRITICALLY ILL PATIENT; DIAGNOSTIC TEST; ELECTROMYOGRAPHY; HIGH RISK PATIENT; HUMAN; INCIDENCE; INTENSIVE CARE WEAKNESS; LENGTH OF STAY; MORTALITY RATE; MUSCLE ATROPHY; MUSCLE WEAKNESS; MYOPATHY; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; CRITICAL ILLNESS; DAILY LIFE ACTIVITY; INTENSIVE CARE UNIT; NEUROMUSCULAR DISEASES; QUALITY OF LIFE;

ACTIVITIES OF DAILY LIVING; CRITICAL ILLNESS; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; NEUROMUSCULAR DISEASES; QUALITY OF LIFE; RISK FACTORS;

EID: 84994430617     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2016.03.045     Document Type: Review

References (85)

1. 1 Osler, W., The Principles and Practice of Medicine, Designed for the Use of Practitioners and Students of Medicine. 1892, D. Appleton and Company, New York.
2. 2 Mertens, H.G., Disseminated neuropathy following coma. On the differentation of so-called toxic polyneuropathy. Nervenarzt 32 (1961), 71–79.
3. 3 Douglass, J.A., Tuxen, D.V., Horne, M., et al. Myopathy in severe asthma. Am Rev Respir Dis 146:2 (1992), 517–519.
4. 4 Campellone, J.V., Lacomis, D., Kramer, D.J., Van Cott, A.C., Giuliani, M.J., Acute myopathy after liver transplantation. Neurology 50:1 (1998), 46–53.
5. 5 Bolton, C.F., Young, G.B., Zochodne, D.W., The neurological complications of sepsis. Ann Neurol 33:1 (1993), 94–100.
6. 6 De Jonghe, B., Sharshar, T., Lefaucheur, J.P., et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 288:22 (2002), 2859–2867.
7. 7 Hermans, G., Van Mechelen, H., Bruyninckx, F., et al. Predictive value for weakness and 1-year mortality of screening electrophysiology tests in the ICU. Intensive Care Med 41:12 (2015), 2138–2148.
8. 8 Moss, M., Yang, M., Macht, M., et al. Screening for critical illness polyneuromyopathy with single nerve conduction studies. Intensive Care Med 40:5 (2014), 683–690.
9. 9 Batt, J., dos Santos, C.C., Cameron, J.I., Herridge, M.S., Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med 187:3 (2013), 238–246.
10. 10 Bolton, C.F., Neuromuscular manifestations of critical illness. Muscle Nerve 32:2 (2005), 140–163.
11. 11 Witt, N.J., Zochodne, D.W., Bolton, C.F., et al. Peripheral nerve function in sepsis and multiple organ failure. Chest 99:1 (1991), 176–184.
12. 12 Bolton, C.F., Brown, J.D., Sibbald, W.A., The electrophysiologic investigation of respiratory paralysis in critically ill patients. Neurology, 33, 1983, 186.
13. 13 Latronico, N., Bolton, C.F., Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 10:10 (2011), 931–941.
14. 14 Helliwell, T.R., Wilkinson, A., Griffiths, R.D., McClelland, P., Palmer, T.E., Bone, J.M., Muscle fibre atrophy in critically ill patients is associated with the loss of myosin filaments and the presence of lysosomal enzymes and ubiquitin. Neuropathol Appl Neurobiol 24:6 (1998), 507–517.
15. 15 Stevens, R.D., Dowdy, D.W., Michaels, R.K., Mendez-Tellez, P.A., Pronovost, P.J., Needham, D.M., Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med 33:11 (2007), 1876–1891.
16. 16 Hough, C.L., Lieu, B.K., Caldwell, E.S., Manual muscle strength testing of critically ill patients: feasibility and interobserver agreement. Crit Care, 15(1), 2011, R43.
17. 17 Connolly, B.A., Jones, G.D., Curtis, A.A., et al. Clinical predictive value of manual muscle strength testing during critical illness: an observational cohort study. Crit Care, 17(5), 2013, R229.
18. 18 Hermans, G., Clerckx, B., Vanhullebusch, T., et al. Interobserver agreement of Medical Research Council sum-score and handgrip strength in the intensive care unit. Muscle Nerve 45:1 (2012), 18–25.
19. 19 Ali, N.A., O'Brien, J.M. Jr., Hoffmann, S.P., et al. Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med 178:3 (2008), 261–268.
20. 20 Latronico, N., Nattino, G., Guarneri, B., et al. Validation of the peroneal nerve test to diagnose critical illness polyneuropathy and myopathy in the intensive care unit: the multicentre Italian CRIMYNE-2 diagnostic accuracy study. F1000Res, 3, 2014, 127.
21. 21 Wieske, L., Verhamme, C., Witteveen, E., et al. Feasibility and diagnostic accuracy of early electrophysiological recordings for ICU-acquired weakness: an observational cohort study. Neurocrit Care 22:3 (2015), 385–394.
22. 22 Bunnell, A., Ney, J., Gellhorn, A., Hough, C.L., Quantitative neuromuscular ultrasound in intensive care unit-acquired weakness: a systematic review. Muscle Nerve 52:5 (2015), 701–708.
23. 23 Puthucheary, Z.A., Rawal, J., McPhail, M., et al. Acute skeletal muscle wasting in critical illness. JAMA 310:15 (2013), 1591–1600.
24. 24 Puthucheary, Z.A., Phadke, R., Rawal, J., et al. Qualitative ultrasound in acute critical illness muscle wasting. Crit Care Med 43:8 (2015), 1603–1611.
25. 25 Fried, L.P., Ferrucci, L., Darer, J., Williamson, J.D., Anderson, G., Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 59:3 (2004), 255–263.
26. 26 Baldwin, M.R., Reid, M.C., Westlake, A.A., et al. The feasibility of measuring frailty to predict disability and mortality in older medical intensive care unit survivors. J Crit Care 29:3 (2014), 401–408.
27. 27 Le Maguet, P., Roquilly, A., Lasocki, S., et al. Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study. Intensive Care Med 40:5 (2014), 674–682.
28. 28 Bagshaw, S.M., Stelfox, H.T., Johnson, J.A., et al. Long-term association between frailty and health-related quality of life among survivors of critical illness: a prospective multicenter cohort study. Crit Care Med 43:5 (2015), 973–982.
29. 29 Iwashyna, T.J., Ely, E.W., Smith, D.M., Langa, K.M., Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA 304:16 (2010), 1787–1794.
30. 30 Iwashyna, T.J., Netzer, G., Langa, K.M., Cigolle, C., Spurious inferences about long-term outcomes: the case of severe sepsis and geriatric conditions. Am J Resp Crit Care Med 185:8 (2012), 835–841.
31. 31 de Letter, M.A., Schmitz, P.I., Visser, L.H., et al. Risk factors for the development of polyneuropathy and myopathy in critically ill patients. Crit Care Med 29:12 (2001), 2281–2286.
32. 32 Leijten, F.S., Harinck-de Weerd, J.E., Poortvliet, D.C., de Weerd, A.W., The role of polyneuropathy in motor convalescence after prolonged mechanical ventilation. JAMA 274:15 (1995), 1221–1225.
33. 33 Bednarik, J., Vondracek, P., Dusek, L., Moravcova, E., Cundrle, I., Risk factors for critical illness polyneuromyopathy. J Neurol 252:3 (2005), 343–351.
34. 34 Amaya-Villar, R., Garnacho-Montero, J., Garcia-Garmendia, J.L., et al. Steroid-induced myopathy in patients intubated due to exacerbation of chronic obstructive pulmonary disease. Intensive Care Med 31:1 (2005), 157–161.
35. 35 Bercker, S., Weber-Carstens, S., Deja, M., et al. Critical illness polyneuropathy and myopathy in patients with acute respiratory distress syndrome. Crit Care Med 33:4 (2005), 711–715.
36. 36 Garnacho-Montero, J., Madrazo-Osuna, J., Garcia-Garmendia, J.L., et al. Critical illness polyneuropathy: risk factors and clinical consequences—a cohort study in septic patients. Intensive Care Med 27:8 (2001), 1288–1296.
37. 37 Kupfer, Y., Namba, T., Kaldawi, E., Tessler, S., Prolonged weakness after long-term infusion of vecuronium bromide. Ann Intern Med 117:6 (1992), 484–486.
38. 38 Lefaucheur, J.P., Nordine, T., Rodriguez, P., Brochard, L., Origin of ICU acquired paresis determined by direct muscle stimulation. J Neurol Neurosurg Psychiatry 77:4 (2006), 500–506.
39. 39 Rudis, M.I., Guslits, B.J., Peterson, E.L., et al. Economic impact of prolonged motor weakness complicating neuromuscular blockade in the intensive care unit. Crit Care Med 24:10 (1996), 1749–1756.
40. 40 Thiele, R.I., Jakob, H., Hund, E., et al. Critical illness polyneuropathy: a new iatrogenically induced syndrome after cardiac surgery?. Eur J Cardiothorac Surg 12:6 (1997), 826–835.
41. 41 Hough, C.L., Steinberg, K.P., Taylor Thompson, B., Rubenfeld, G.D., Hudson, L.D., Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS. Intensive Care Med 35:1 (2009), 63–68.
42. 42 Garnacho-Montero, J., Amaya-Villar, R., Garcia-Garmendia, J.L., Madrazo-Osuna, J., Ortiz-Leyba, C., Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients. Crit Care Med 33:2 (2005), 349–354.
43. 43 Papazian, L., Forel, J.M., Gacouin, A., et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:12 (2010), 1107–1116.
44. 44 van den Berghe, G., Wouters, P., Weekers, F., et al. Intensive insulin therapy in critically ill patients. N Engl J Med 345:19 (2001), 1359–1367.
45. 45 Mitchell, K.H., Carlbom, D., Caldwell, E., Leary, P.J., Himmelfarb, J., Hough, C.L., Volume overload: prevalence, risk factors, and functional outcome in survivors of septic shock. Ann Am Thorac Soc 12:12 (2015), 1837–1844.
46. 46 Parsons, E.C., Kross, E.K., Ali, N.A., et al. Red blood cell transfusion is associated with decreased in-hospital muscle strength among critically ill patients requiring mechanical ventilation. J Crit Care 28:6 (2013), 1079–1085.
47. 47 Convertino, V.A., Bloomfield, S.A., Greenleaf, J.E., An overview of the issues: physiological effects of bed rest and restricted physical activity. Med Sci Sports Exerc 29:2 (1997), 187–190.
48. 48 Kasper, C.E., Talbot, L.A., Gaines, J.M., Skeletal muscle damage and recovery. AACN Clin Issues 13:2 (2002), 237–247.
49. 49 Sargeant, A.J., Davies, C.T., Edwards, R.H., Maunder, C., Young, A., Functional and structural changes after disuse of human muscle. Clin Sci Mol Med 52:4 (1977), 337–342.
50. 50 Kortebein, P., Ferrando, A., Lombeida, J., Wolfe, R., Evans, W.J., Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA 297:16 (2007), 1772–1774.
51. 51 Topp, R., Ditmyer, M., King, K., Doherty, K., Hornyak, J. III, The effect of bed rest and potential of prehabilitation on patients in the intensive care unit. AACN Clin Issues 13:2 (2002), 263–276.
52. 52 Berg, H.E., Larsson, L., Tesch, P.A., Lower limb skeletal muscle function after 6 wk of bed rest. J Appl Physiol 82:1 (1997), 182–188.
53. 53 Herridge, M.S., Cheung, A.M., Tansey, C.M., et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 348:8 (2003), 683–693.
54. 54 Hermans, G., Van Mechelen, H., Clerckx, B., et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med 190:4 (2014), 410–420.
55. 55 Sharshar, T., Bastuji-Garin, S., Stevens, R.D., et al. Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med 37:12 (2009), 3047–3053.
56. 56 Fan, E., Dowdy, D.W., Colantuoni, E., et al. Physical complications in acute lung injury survivors: a two-year longitudinal prospective study. Crit Care Med 42:4 (2014), 849–859.
57. 57 Wieske, L., Dettling-Ihnenfeldt, D.S., Verhamme, C., et al. Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study. Crit Care, 19, 2015, 196.
58. 58 Griffiths, R.D., Palmer, T.E., Helliwell, T., et al. Effect of passive stretching on the wasting of muscle in the critically ill. Nutrition 11:5 (1995), 428–432.
59. 59 Hermans, G., De Jonghe, B., Bruyninckx, F., Van den Berghe, G., Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev(1), 2009, CD006832.
60. 60 Burtin, C., Clerckx, B., Robbeets, C., et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med 37:9 (2009), 2499–2505.
61. 61 Morris, P.E., Goad, A., Thompson, C., et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med 36:8 (2008), 2238–2243.
62. 62 Schweickert, W.D., Pohlman, M.C., Pohlman, A.S., et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 373:9678 (2009), 1874–1882.
63. 63 Angelopoulos, E., Karatzanos, E., Dimopoulos, S., et al. Acute microcirculatory effects of medium frequency versus high frequency neuromuscular electrical stimulation in critically ill patients - a pilot study. Ann Intensive Care, 3(1), 2013, 39.
64. 64 Kho, M.E., Truong, A.D., Zanni, J.M., et al. Neuromuscular electrical stimulation in mechanically ventilated patients: a randomized, sham-controlled pilot trial with blinded outcome assessment. J Crit Care 30:1 (2015), 32–39.
65. 65 Dirks, M.L., Hansen, D., van Assche, A., et al. Neuromuscular electrical stimulation prevents muscle wasting in critically ill comatose patients. Clin Sci (Lond) 128:6 (2015), 357–365.
66. 66 Bailey, P., Thomsen, G.E., Spuhler, V.J., et al. Early activity is feasible and safe in respiratory failure patients. Crit Care Med 35:1 (2007), 139–145.
67. 67 Morris, P.E., Griffin, L., Berry, M., et al. Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure. Am J Med Sci 341:5 (2011), 373–377.
68. 68 Needham, D.M., Korupolu, R., Zanni, J.M., et al. Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. Arch Phys Med Rehabil 91:4 (2010), 536–542.
69. 69 Kayambu, G., Boots, R., Paratz, J., Physical therapy for the critically ill in the ICU: a systematic review and meta-analysis. Crit Care Med 41:6 (2013), 1543–1554.
70. 70 Berney, S.C., Harrold, M., Webb, S.A., et al. Intensive care unit mobility practices in Australia and New Zealand: a point prevalence study. Crit Care Resusc 15:4 (2013), 260–265.
71. 71 Nydahl, P., Ruhl, A.P., Bartoszek, G., et al. Early mobilization of mechanically ventilated patients: a 1-day point-prevalence study in Germany. Crit Care Med 42:5 (2014), 1178–1186.
72. 72 Novak, P., Vidmar, G., Kuret, Z., Bizovičar, N., Rehabilitation of critical illness polyneuropathy and myopathy patients: an observational study. Int J Rehabil Res 34:4 (2011), 336–342.
73. 73 Somme, D., Andrieux, N., Guerot, E., et al. Loss of autonomy among elderly patients after a stay in a medical intensive care unit (ICU): a randomized study of the benefit of transfer to a geriatric ward. Arch Gerontol Geriatr 50:3 (2010), e36–e40.
74. 74 Elliott, D., McKinley, S., Alison, J., et al. Health-related quality of life and physical recovery after a critical illness: a multi-centre randomised controlled trial of a home-based physical rehabilitation program. Crit Care, 15(3), 2011, R142.
75. 75 Jones, C., Skirrow, P., Griffiths, R.D., et al. Rehabilitation after critical illness: a randomized, controlled trial. Crit Care Med 31:10 (2003), 2456–2461.
76. 76 Klein, M.B., Lezotte, D.L., Fauerbach, J.A., et al. The National Institute on Disability and Rehabilitation Research burn model system database: a tool for the multicenter study of the outcome of burn injury. J Burn Care Res 28:1 (2007), 84–96.
77. 77 Parent, S., Barchi, S., LeBreton, M., Casha, S., Fehlings, M.G., The impact of specialized centers of care for spinal cord injury on length of stay, complications, and mortality: a systematic review of the literature. J Neurotrauma 28:8 (2011), 1363–1370.
78. 78 Fan, E., Cheek, F., Chlan, L., et al. An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med 190:12 (2014), 1437–1446.
79. 79 Latronico, N., Fenzi, F., Recupero, D., et al. Critical illness myopathy and neuropathy. Lancet 347:9015 (1996), 1579–1582.
80. 80 Thrush, A., Rozek, M., Dekerlegand, J.L., The clinical utility of the functional status score for the intensive care unit (FSS-ICU) at a long-term acute care hospital: a prospective cohort study. Phys Ther 92:12 (2012), 1536–1545.
81. 81 Parry, S.M., Denehy, L., Beach, L.J., Berney, S., Williamson, H.C., Granger, C.L., Functional outcomes in ICU: what should we be using? An observational study. Crit Care, 19(1), 2015, 127.
82. 82 Denehy, L., de Morton, N.A., Skinner, E.H., et al. A physical function test for use in the intensive care unit: validity, responsiveness, and predictive utility of the physical function ICU test (scored). Phys Ther 93:12 (2013), 1636–1645.
83. 83 Skinner, E.H., Berney, S., Warrillow, S., Denehy, L., Development of a physical function outcome measure (PFIT) and a pilot exercise training protocol for use in intensive care. Crit Care Resusc 11:2 (2009), 110–115.
84. 84 Cox, C.E., Porter, L.S., Buck, P.J., et al. Development and preliminary evaluation of a telephone-based mindfulness training intervention for survivors of critical illness. Ann Am Thorac Soc 11:2 (2014), 173–181.
85. 85 Iwashyna, T.J., Netzer, G., The burdens of survivorship: an approach to thinking about long-term outcomes after critical illness. Semin Respir Crit Care Med 33:4 (2012), 327–338.