Muscle fibre atrophy in critically ill patients is associated with the loss of myosin filaments and the presence of lysosomal enzymes and ubiquitin

Neuropathology and Applied Neurobiology

Volumn 24, Issue 6, 1998, Pages 507-517

  Helliwell, T R ^a   Wilkinson, A ^a   Griffiths, R D ^a   McClelland, P ^a   Palmer, T E A ^a   Bone, J M ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Atrophy; Immunohistochemistry; Intensive care; Myosin; Pathology; Proteolysis; Skeletal muscle

Indexed keywords

ACTIN; CATHEPSIN B; DESMIN; DYSTROPHIN; HEAT SHOCK PROTEIN 72; LYSOSOME ENZYME; MYOSIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN HEAVY CHAIN; PROTEINASE; UBIQUITIN;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; CRITICAL ILLNESS; CYTOSKELETON; DEPOLYMERIZATION; ELECTRON MICROSCOPY; ENZYME ACTIVITY; HOSPITALIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE NECROSIS; MYOPATHY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ADULT; AGED; BIOPSY; CATHEPSIN B; CONTRACTILE PROTEINS; CRITICAL ILLNESS; CYTOSKELETAL PROTEINS; DESMIN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYSOSOMES; MICROSCOPY, ELECTRON; MIDDLE AGED; MURAMIDASE; MUSCLE FIBERS; MUSCULAR ATROPHY; MYOSINS; UBIQUITINS;

EID: 0032442182     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2990.1998.00144.x     Document Type: Article

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