Predictive value for weakness and 1-year mortality of screening electrophysiology tests in the ICU

Intensive Care Medicine

Volumn 41, Issue 12, 2015, Pages 2138-2148

  Hermans, Greet ^a,b   Van Mechelen, Helena ^a   Bruyninckx, Frans ^b   Vanhullebusch, Tine ^a   Clerckx, Beatrix ^b   Meersseman, Philippe ^b   Debaveye, Yves ^a,b   Casaer, Michael P ^a,b   Wilmer, Alexander ^b   Wouters, Pieter J ^a,b   Vanhorebeek, Ilse ^a   Gosselink, Rik ^c   Van den Berghe, Greet ^a,b  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Electrophysiology; Intensive care; Mortality; Muscle weakness

Indexed keywords

ADULT; AGED; ARTICLE; DIAGNOSTIC TEST ACCURACY STUDY; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; FEMALE; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MUSCLE ACTION POTENTIAL; MUSCLE WEAKNESS; NEUROMUSCULAR DISEASE; PREDICTIVE VALUE; PROSPECTIVE STUDY; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SENSORY NERVE; CONTROLLED STUDY; ELECTRODIAGNOSIS; MIDDLE AGED; MORTALITY; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; TIME FACTOR;

AGED; ELECTRODIAGNOSIS; ELECTROPHYSIOLOGICAL PROCESSES; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MUSCLE WEAKNESS; PREDICTIVE VALUE OF TESTS; TIME FACTORS;

EID: 84946473369     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-015-3979-7     Document Type: Article

References (43)

1. Kress JP, Hall JB (2014) ICU-acquired weakness and recovery from critical illness. N Engl J Med 370:1626–1635
2. Fan E, Cheek F, Chlan L, Gosselink R, Hart N, Herridge MS, Hopkins RO, Hough CL, Kress JP, Latronico N, Moss M, Needham DM, Rich MM, Stevens RD, Wilson KC, Winkelman C, Zochodne DW, Ali NA, ATS Committee on ICU-acquired Weakness in Adults, American Thoracic Society (2014) An official American Thoracic Society clinical practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med 190:1437–1446
3. De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, Cerf C, Renaud E, Mesrati F, Carlet J, Raphael JC, Outin H, Bastuji-Garin S (2002) Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 288:2859–2867
4. Stevens RD, Dowdy DW, Michaels RK, Mendez-Tellez PA, Pronovost PJ, Needham DM (2007) Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med 33:1876–1891
5. De Jonghe B, Bastuji-Garin S, Durand MC, Malissin I, Rodrigues P, Cerf C, Outin H, Sharshar T (2007) Respiratory weakness is associated with limb weakness and delayed weaning in critical illness. Crit Care Med 35:2007–2015
6. Sharshar T, Bastuji-Garin S, Stevens RD, Durand MC, Malissin I, Rodriguez P, Cerf C, Outin H, De Jonghe B (2009) Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med 37:3047–3053
7. Ali NA, O’Brien JM Jr, Hoffmann SP, Phillips G, Garland A, Finley JC, Almoosa K, Hejal R, Wolf KM, Lemeshow S, Connors AF Jr, Marsh CB (2008) Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med 178:261–268
8. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, Casaer MP, Meersseman P, Debaveye Y, Van Cromphaut S, Wouters PJ, Gosselink R, Van den Berghe G (2014) Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med 190:410–420
9. Herridge MS, Tansey CM, Matte A, Tomlinson G, az-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM (2011) Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 364:1293–1304
10. Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Shanholtz C, Himmelfarb CR, Desai SV, Ciesla N, Herridge MS, Pronovost PJ, Needham DM (2014) Physical complications in acute lung injury survivors: a two-year longitudinal prospective study. Crit Care Med 42:849–859
11. Hermans G, Casaer MP, Clerckx B, Guiza F, Vanhullebusch T, Derde S, Meersseman P, Derese I, Mesotten D, Wouters P, Van Cromphaut S, Debaveye Y, Gosselink R, Gunst J, Wilmer A, Van den Berghe G, Vanhorebeek I (2013) Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial. Lancet Respir Med 1:621–629
12. Latronico N, Bolton CF (2011) Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 10:931–941
13. Lacomis D (2013) Electrophysiology of neuromuscular disorders in critical illness. Muscle Nerve 47:452–463
14. Latronico N, Smith M (2014) Introducing simplified electrophysiological test of peripheral nerves and muscles in the ICU: choosing wisely. Intensive Care Med 40:746–748
15. Moss M, Yang M, Macht M, Sottile P, Gray L, McNulty M, Quan D (2014) Screening for critical illness polyneuromyopathy with single nerve conduction studies. Intensive Care Med 40:683–690
16. Moons KG, Altman DG, Reitsma JB, Ioannidis JP, Macaskill P, Steyerberg EW, Vickers AJ, Ransohoff DF, Collins GS (2015) Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med 162:W1–73
17. Casaer MP, Hermans G, Wilmer A, Van den Berghe G (2011) Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial. Trials 12:21
18. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, Vlasselaers D, Debaveye Y, Desmet L, Dubois J, Van Assche A, Vanderheyden S, Wilmer A, Van den Berghe G (2011) Early versus late parenteral nutrition in critically ill adults. N Engl J Med 365:506–517
19. Latronico N, Bertolini G, Guarneri B, Botteri M, Peli E, Andreoletti S, Bera P, Luciani D, Nardella A, Vittorielli E, Simini B, Candiani A (2007) Simplified electrophysiological evaluation of peripheral nerves in critically ill patients: the Italian multi-centre CRIMYNE study. Crit Care 11:R11
20. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, Casaer MP, Meersseman P, Debaveye Y, Van Cromphaut S, Wouters PJ, Gosselink R, Van den Berghe G (2014) Acute outcomes and 1-year mortality of ICU-acquired weakness: a cohort study and propensity matched analysis. Am J Respir Crit Care Med 190:410–420
21. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Moher D, Rennie D, de Vet HC, Lijmer JG, Standards for Reporting of Diagnostic Accuracy Group (2003) The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Ann Intern Med 138:W1–12
22. Midi H, Sarkar SK, Rana S (2010) Collinearity diagnostics of binary logistic regression model. J Interdiscip Math 13:253–267
23. SAS Institute (1999) StatView: Using StatView. SAS Institute, ISBN 9781580251624
24. Latronico N, Nattino G, Guarneri B, Fagoni N, Amantini A, Bertolini G, Gi VSI (2014) Validation of the peroneal nerve test to diagnose critical illness polyneuropathy and myopathy in the intensive care unit: the multicentre Italian CRIMYNE-2 diagnostic accuracy study. F1000Res 3:127
25. Weber-Carstens S, Koch S, Spuler S, Spies CD, Bubser F, Wernecke KD, Deja M (2009) Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients. Crit Care Med 37:2632–2637
26. Wieske L, Verhamme C, Witteveen E, Bouwes A, Dettling-Ihnenfeldt DS, van der Schaaf M, Schultz MJ, van Schaik IN, Horn J (2015) Feasibility and diagnostic accuracy of early electrophysiological recordings for ICU-acquired weakness: an observational cohort study. Neurocrit Care 22:385–394
27. Bednarik J, Lukas Z, Vondracek P (2003) Critical illness polyneuromyopathy: the electrophysiological components of a complex entity. Intensive Care Med 29:1505–1514
28. Witt NJ, Zochodne DW, Bolton CF, Grand’Maison F, Wells G, Young GB, Sibbald WJ (1991) Peripheral nerve function in sepsis and multiple organ failure. Chest 99:176–184
29. Lefaucheur JP, Nordine T, Rodriguez P, Brochard L (2006) Origin of ICU acquired paresis determined by direct muscle stimulation. J Neurol Neurosurg Psychiatry 77:500–506
30. Zifko UA, Zipko HT, Bolton CF (1998) Clinical and electrophysiological findings in critical illness polyneuropathy. J Neurol Sci 159:186–193
31. Tennila A, Salmi T, Pettila V, Roine RO, Varpula T, Takkunen O (2000) Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsis. Intensive Care Med 26:1360–1363
32. Cankayali I, Dogan YH, Solak I, Demirag K, Eris O, Demirgoren S, Moral AR (2007) Neuromuscular deterioration in the early stage of sepsis in rats. Crit Care 11:R1
33. Van den Berghe G, Schoonheydt K, Becx P, Bruyninckx F, Wouters PJ (2005) Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology 64:1348–1353
34. Hermans G, Wilmer A, Meersseman W, Milants I, Wouters PJ, Bobbaers H, Bruyninckx F, Van den Berghe G (2007) Impact of intensive insulin therapy on neuromuscular complications and ventilator-dependency in MICU. Am J Respir Crit Care Med 175:480–489
35. Garnacho-Montero J, Madrazo-Osuna J, Garcia-Garmendia JL, Ortiz-Leyba C, Jimenez-Jimenez FJ, Barrero-Almodovar A, Garnacho-Montero MC, Moyano-Del-Estad MR (2001) Critical illness polyneuropathy: risk factors and clinical consequences. A cohort study in septic patients. Intensive Care Med 27:1288–1296
36. Garnacho-Montero J, Amaya-Villar R, Garcia-Garmendia JL, Madrazo-Osuna J, Ortiz-Leyba C (2005) Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients. Crit Care Med 33:349–354
37. Khan J, Harrison TB, Rich MM, Moss M (2006) Early development of critical illness myopathy and neuropathy in patients with severe sepsis. Neurology 67:1421–1425
38. Leijten FS, Harinck-de Weerd JE, Poortvliet DC, de Weerd AW (1995) The role of polyneuropathy in motor convalescence after prolonged mechanical ventilation. JAMA 274:1221–1225
39. Druschky A, Herkert M, Radespiel-Troger M, Druschky K, Hund E, Becker CM, Hilz MJ, Erbguth F, Neundorfer B (2001) Critical illness polyneuropathy: clinical findings and cell culture assay of neurotoxicity assessed by a prospective study. Intensive Care Med 27:686–693
40. Weber-Carstens S, Schneider J, Wollersheim T, Assmann A, Bierbrauer J, Marg A, Al Hasani H, Chadt A, Wenzel K, Koch S, Fielitz J, Kleber C, Faust K, Mai K, Spies CD, Luft FC, Boschmann M, Spranger J, Spuler S (2013) Critical illness myopathy and GLUT4: significance of insulin and muscle contraction. Am J Respir Crit Care Med 187:387–396
41. Latronico N, Fenzi F, Recupero D, Guarneri B, Tomelleri G, Tonin P, De Maria G, Antonini L, Rizzuto N, Candiani A (1996) Critical illness myopathy and neuropathy. Lancet 347:1579–1582
42. Rich MM, Bird SJ, Raps EC, McCluskey LF, Teener JW (1997) Direct muscle stimulation in acute quadriplegic myopathy. Muscle Nerve 20:665–673
43. Trojaborg W, Weimer LH, Hays AP (2001) Electrophysiologic studies in critical illness associated weakness: myopathy or neuropathy—a reappraisal. Clin Neurophysiol 112:1586–1593