-
2
-
-
0030814886
-
Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects
-
Knowles MR, Robinson JM, Wood RE, Pue CA, Mentz WM, Wager GC, Gatzy JT, Boucher RC. Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects. J Clin Invest 1997;100: 2588-2595.
-
(1997)
J Clin Invest
, vol.100
, pp. 2588-2595
-
-
Knowles, M.R.1
Robinson, J.M.2
Wood, R.E.3
Pue, C.A.4
Mentz, W.M.5
Wager, G.C.6
Gatzy, J.T.7
Boucher, R.C.8
-
3
-
-
0032433707
-
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
-
Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 1998;95:1005-1015.
-
(1998)
Cell
, vol.95
, pp. 1005-1015
-
-
Matsui, H.1
Grubb, B.R.2
Tarran, R.3
Randell, S.H.4
Gatzy, J.T.5
Davis, C.W.6
Boucher, R.C.7
-
4
-
-
33845992179
-
Evidence for airway surface dehydration as the initiating event in CF airway disease
-
Boucher RC. Evidence for airway surface dehydration as the initiating event in CF airway disease. J Intern Med 2007;261:5-16.
-
(2007)
J Intern Med
, vol.261
, pp. 5-16
-
-
Boucher, R.C.1
-
7
-
-
84937631483
-
Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy
-
Cantin AM, Hartl D, Konstan MW, Chmiel JF. Inflammation in cystic fibrosis lung disease: pathogenesis and therapy. J Cyst Fibros 2015; 14:419-430.
-
(2015)
J Cyst Fibros
, vol.14
, pp. 419-430
-
-
Cantin, A.M.1
Hartl, D.2
Konstan, M.W.3
Chmiel, J.F.4
-
8
-
-
0033548702
-
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
-
Jaquemar D, Schenker T, Trueb B. An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J Biol Chem 1999;274: 7325-7333.
-
(1999)
J Biol Chem
, vol.274
, pp. 7325-7333
-
-
Jaquemar, D.1
Schenker, T.2
Trueb, B.3
-
9
-
-
52549112698
-
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4, 5-biphosphate manipulators
-
Karashima Y, Prenen J, Meseguer V, Owsianik G, Voets T, Nilius B. Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4, 5-biphosphate manipulators. Pflugers Arch 2008;457:77-89.
-
(2008)
Pflugers Arch
, vol.457
, pp. 77-89
-
-
Karashima, Y.1
Prenen, J.2
Meseguer, V.3
Owsianik, G.4
Voets, T.5
Nilius, B.6
-
10
-
-
24644462327
-
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
-
Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, Dai Y, Fukuoka T, Tokunaga A, Tominaga M, Noguchi K. TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J Clin Invest 2005;115:2393-2401.
-
(2005)
J Clin Invest
, vol.115
, pp. 2393-2401
-
-
Obata, K.1
Katsura, H.2
Mizushima, T.3
Yamanaka, H.4
Kobayashi, K.5
Dai, Y.6
Fukuoka, T.7
Tokunaga, A.8
Tominaga, M.9
Noguchi, K.10
-
11
-
-
46749091281
-
Cigarette smoke-induced neurogenic inflammation is mediated by a, b-unsaturated aldehydes and the TRPA1 receptor in rodents
-
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, et al. Cigarette smoke-induced neurogenic inflammation is mediated by a, b-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest 2008;118:2574-2582.
-
(2008)
J Clin Invest
, vol.118
, pp. 2574-2582
-
-
Andrè, E.1
Campi, B.2
Materazzi, S.3
Trevisani, M.4
Amadesi, S.5
Massi, D.6
Creminon, C.7
Vaksman, N.8
Nassini, R.9
Civelli, M.10
-
12
-
-
67049119907
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
-
Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, DAmours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, et al. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA 2009;106: 9099-9104.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9099-9104
-
-
Caceres, A.I.1
Brackmann, M.2
Elia, M.D.3
Bessac, B.F.4
Del Camino, D.5
Damours, M.6
Witek, J.S.7
Fanger, C.M.8
Chong, J.A.9
Hayward, N.J.10
-
13
-
-
84865052691
-
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation
-
Nassini R, Pedretti P, Moretto N, Fusi C, Carnini C, Facchinetti F, Viscomi AR, Pisano AR, Stokesberry S, Brunmark C, et al. Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One 2012;7: e42454.
-
(2012)
PLoS One
, vol.7
, pp. e42454
-
-
Nassini, R.1
Pedretti, P.2
Moretto, N.3
Fusi, C.4
Carnini, C.5
Facchinetti, F.6
Viscomi, A.R.7
Pisano, A.R.8
Stokesberry, S.9
Brunmark, C.10
-
14
-
-
79955029152
-
Phospholipase C-b3 is a key modulator of IL-8 expression in cystic fibrosis bronchial epithelial cells
-
Bezzerri V, dAdamo P, Rimessi A, Lanzara C, Crovella S, Nicolis E, Tamanini A, Athanasakis E, Tebon M, Bisoffi G, et al. Phospholipase C-b3 is a key modulator of IL-8 expression in cystic fibrosis bronchial epithelial cells. J Immunol 2011;186:4946-4958.
-
(2011)
J Immunol
, vol.186
, pp. 4946-4958
-
-
Bezzerri, V.1
Dadamo, P.2
Rimessi, A.3
Lanzara, C.4
Crovella, S.5
Nicolis, E.6
Tamanini, A.7
Athanasakis, E.8
Tebon, M.9
Bisoffi, G.10
-
15
-
-
84928706286
-
Mitochondrial Ca21-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
-
Rimessi A, Bezzerri V, Patergnani S, Marchi S, Cabrini G, Pinton P. Mitochondrial Ca21-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis. Nat Commun 2015;6:6201.
-
(2015)
Nat Commun
, vol.6
, pp. 6201
-
-
Rimessi, A.1
Bezzerri, V.2
Patergnani, S.3
Marchi, S.4
Cabrini, G.5
Pinton, P.6
-
16
-
-
0028784322
-
Inflammatory cytokines in cystic fibrosis lungs
-
Bonfield TL, Panuska JR, Konstan MW, Hilliard KA, Hilliard JB, Ghnaim H, Berger M. Inflammatory cytokines in cystic fibrosis lungs. Am J Respir Crit Care Med 1995;152:2111-2118.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 2111-2118
-
-
Bonfield, T.L.1
Panuska, J.R.2
Konstan, M.W.3
Hilliard, K.A.4
Hilliard, J.B.5
Ghnaim, H.6
Berger, M.7
-
17
-
-
0034653569
-
High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the IkB kinase a pathway in response to extracellular NaCl content
-
Tabary O, Escotte S, Couetil JP, Hubert D, Dusser D, Puchelle E, Jacquot J. High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the IkB kinase a pathway in response to extracellular NaCl content. J Immunol 2000;164: 3377-3384.
-
(2000)
J Immunol
, vol.164
, pp. 3377-3384
-
-
Tabary, O.1
Escotte, S.2
Couetil, J.P.3
Hubert, D.4
Dusser, D.5
Puchelle, E.6
Jacquot, J.7
-
18
-
-
84884135043
-
Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity
-
Zhou Y, Suzuki Y, Uchida K, Tominaga M. Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity. Nat Commun 2013;4:2399.
-
(2013)
Nat Commun
, vol.4
, pp. 2399
-
-
Zhou, Y.1
Suzuki, Y.2
Uchida, K.3
Tominaga, M.4
-
19
-
-
24044466139
-
Chronic airway infection/inflammation induces a Ca21 i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia
-
Ribeiro CM, Paradiso AM, Schwab U, Perez-Vilar J, Jones L, Oneal W, Boucher RC. Chronic airway infection/inflammation induces a Ca21 i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia. J Biol Chem 2005;280: 17798-17806.
-
(2005)
J Biol Chem
, vol.280
, pp. 17798-17806
-
-
Ribeiro, C.M.1
Paradiso, A.M.2
Schwab, U.3
Perez-Vilar, J.4
Jones, L.5
Oneal, W.6
Boucher, R.C.7
-
20
-
-
79955581526
-
TRP channels: Emerging targets for respiratory disease
-
Banner KH, Igney F, Poll C. TRP channels: emerging targets for respiratory disease. Pharmacol Ther 2011;130:371-384.
-
(2011)
Pharmacol Ther
, vol.130
, pp. 371-384
-
-
Banner, K.H.1
Igney, F.2
Poll, C.3
-
21
-
-
78650675175
-
Transient receptor potential canonical channel 6 links Ca21 mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis
-
Antigny F, Norez C, Dannhoffer L, Bertrand J, Raveau D, Corbi P, Jayle C, Becq F, Vandebrouck C. Transient receptor potential canonical channel 6 links Ca21 mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis. Am J Respir Cell Mol Biol 2011;44:83-90.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 83-90
-
-
Antigny, F.1
Norez, C.2
Dannhoffer, L.3
Bertrand, J.4
Raveau, D.5
Corbi, P.6
Jayle, C.7
Becq, F.8
Vandebrouck, C.9
-
22
-
-
82755162139
-
Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells
-
Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R, Cabrini G. Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. J Immunol 2011;187:6069-6081.
-
(2011)
J Immunol
, vol.187
, pp. 6069-6081
-
-
Bezzerri, V.1
Borgatti, M.2
Finotti, A.3
Tamanini, A.4
Gambari, R.5
Cabrini, G.6
-
23
-
-
84884319918
-
Transient receptor potential ankyrin-1 (TRPA1) modulates storeoperated Ca21 entry by regulation of STIM1-Orai1 association
-
Albarrá n L, Lopez JJ, Dionisio N, Smani T, Salido GM, Rosado JA. Transient receptor potential ankyrin-1 (TRPA1) modulates storeoperated Ca21 entry by regulation of STIM1-Orai1 association. Biochim Biophys Acta 2013;1833:3025-3034.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3025-3034
-
-
Albarrá, N.L.1
Lopez, J.J.2
Dionisio, N.3
Smani, T.4
Salido, G.M.5
Rosado, J.A.6
-
24
-
-
84946949581
-
Reciprocal regulation of mitochondrial dynamics and calcium signaling in astrocyte processes
-
Jackson JG, Robinson MB. Reciprocal regulation of mitochondrial dynamics and calcium signaling in astrocyte processes. J Neurosci 2015;35:15199-15213.
-
(2015)
J Neurosci
, vol.35
, pp. 15199-15213
-
-
Jackson, J.G.1
Robinson, M.B.2
-
25
-
-
33751032385
-
Calcium microdomains: Organization and function
-
Berridge MJ. Calcium microdomains: organization and function. Cell Calcium 2006;40:405-412.
-
(2006)
Cell Calcium
, vol.40
, pp. 405-412
-
-
Berridge, M.J.1
-
26
-
-
33644847375
-
Microdomains of intracellular Ca21: Molecular determinants and functional consequences
-
Rizzuto R, Pozzan T. Microdomains of intracellular Ca21: molecular determinants and functional consequences. Physiol Rev 2006;86: 369-408.
-
(2006)
Physiol Rev
, vol.86
, pp. 369-408
-
-
Rizzuto, R.1
Pozzan, T.2
-
28
-
-
32244441372
-
The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia
-
Ribeiro CM. The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia. Drugs R D 2006;7:17-31.
-
(2006)
Drugs R D
, vol.7
, pp. 17-31
-
-
Ribeiro, C.M.1
-
29
-
-
79952668061
-
Role of endoplasmic reticulum stress in cystic fibrosis-related airway inflammatory responses
-
Ribeiro CM, Boucher RC. Role of endoplasmic reticulum stress in cystic fibrosis-related airway inflammatory responses. Proc Am Thorac Soc 2010;7:387-394.
-
(2010)
Proc Am Thorac Soc
, vol.7
, pp. 387-394
-
-
Ribeiro, C.M.1
Boucher, R.C.2
-
30
-
-
84902333338
-
Ca21 signaling and fluid secretion by secretory cells of the airway epithelium
-
Lee RJ, Foskett JK. Ca21 signaling and fluid secretion by secretory cells of the airway epithelium. Cell Calcium 2014;55:325-336.
-
(2014)
Cell Calcium
, vol.55
, pp. 325-336
-
-
Lee, R.J.1
Foskett, J.K.2
-
31
-
-
57749111494
-
Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control
-
Bessac BF, Jordt SE. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. Physiology (Bethesda) 2008;23:360-370.
-
(2008)
Physiology (Bethesda
, vol.23
, pp. 360-370
-
-
Bessac, B.F.1
Jordt, S.E.2
-
33
-
-
40449121206
-
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress
-
Andersson DA, Gentry C, Moss S, Bevan S. Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress. J Neurosci 2008;28:2485-2494.
-
(2008)
J Neurosci
, vol.28
, pp. 2485-2494
-
-
Andersson, D.A.1
Gentry, C.2
Moss, S.3
Bevan, S.4
-
34
-
-
76749098786
-
Characterization of hydrogen peroxide production by Duox in bronchial epithelial cells exposed to Pseudomonas aeruginosa
-
Rada B, Leto TL. Characterization of hydrogen peroxide production by Duox in bronchial epithelial cells exposed to Pseudomonas aeruginosa. FEBS Lett 2010;584:917-922.
-
(2010)
FEBS Lett
, vol.584
, pp. 917-922
-
-
Rada, B.1
Leto, T.L.2
-
35
-
-
84858294319
-
Working group on inflammation in cystic fibrosis oxidative stress and antioxidant therapy in cystic fibrosis
-
Galli F, Battistoni A, Gambari R, Pompella A, Bragonzi A, Pilolli F, Iuliano L, Piroddi M, Dechecchi MC, Cabrini G; Working Group on Inflammation in Cystic Fibrosis. Oxidative stress and antioxidant therapy in cystic fibrosis. Biochim Biophys Acta 2012;1822: 690-713.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 690-713
-
-
Galli, F.1
Battistoni, A.2
Gambari, R.3
Pompella, A.4
Bragonzi, A.5
Pilolli, F.6
Iuliano, L.7
Piroddi, M.8
Dechecchi, M.C.9
Cabrini, G.10
-
36
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Hö gestä tt ED, Meng ID, Julius D. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 2004;427:260-265.
-
(2004)
Nature
, vol.427
, pp. 260-265
-
-
Jordt, S.E.1
Bautista, D.M.2
Chuang, H.H.3
McKemy, D.D.4
Zygmunt, P.M.5
Högestätt, E.D.6
Meng, I.D.7
Julius, D.8
-
37
-
-
44949182742
-
Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: A molecular mechanism of inflammatory pain
-
Wang S, Dai Y, Fukuoka T, Yamanaka H, Kobayashi K, Obata K, Cui X, Tominaga M, Noguchi K. Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: A molecular mechanism of inflammatory pain. Brain 2008;131:1241-1251.
-
(2008)
Brain
, vol.131
, pp. 1241-1251
-
-
Wang, S.1
Dai, Y.2
Fukuoka, T.3
Yamanaka, H.4
Kobayashi, K.5
Obata, K.6
Cui, X.7
Tominaga, M.8
Noguchi, K.9
-
38
-
-
34447121851
-
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
-
Dai Y, Wang S, Tominaga M, Yamamoto S, Fukuoka T, Higashi T, Kobayashi K, Obata K, Yamanaka H, Noguchi K. Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest 2007;117:1979-1987.
-
(2007)
J Clin Invest
, vol.117
, pp. 1979-1987
-
-
Dai, Y.1
Wang, S.2
Tominaga, M.3
Yamamoto, S.4
Fukuoka, T.5
Higashi, T.6
Kobayashi, K.7
Obata, K.8
Yamanaka, H.9
Noguchi, K.10
-
39
-
-
34250379970
-
Transient receptor potential channel A1 is directly gated by calcium ions
-
Doerner JF, Gisselmann G, Hatt H, Wetzel CH. Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem 2007;282:13180-13189.
-
(2007)
J Biol Chem
, vol.282
, pp. 13180-13189
-
-
Doerner, J.F.1
Gisselmann, G.2
Hatt, H.3
Wetzel, C.H.4
-
40
-
-
33847241778
-
Direct activation of the ion channel TRPA1 by Ca21
-
Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA. Direct activation of the ion channel TRPA1 by Ca21. Nat Neurosci 2007;10:277-279.
-
(2007)
Nat Neurosci
, vol.10
, pp. 277-279
-
-
Zurborg, S.1
Yurgionas, B.2
Jira, J.A.3
Caspani, O.4
Heppenstall, P.A.5
-
41
-
-
0035979172
-
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
-
McNamara N, Khong A, McKemy D, Caterina M, Boyer J, Julius D, Basbaum C. ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor. Proc Natl Acad Sci USA 2001;98: 9086-9091.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9086-9091
-
-
McNamara, N.1
Khong, A.2
McKemy, D.3
Caterina, M.4
Boyer, J.5
Julius, D.6
Basbaum, C.7
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