메뉴 건너뛰기




Volumn 43, Issue 11, 2016, Pages 1956-1964

Chronic nonbacterial osteomyelitis: Pathophysiological concepts and current treatment strategies

Author keywords

CHRONIC NONBACTERIAL OSTEOMYELITIS; CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS; CYTOKINE; INFLAMMATION; TREATMENT

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CORTICOSTEROID; CRYOPYRIN; DISEASE MODIFYING ANTIRHEUMATIC DRUG; EOTAXIN; ETANERCEPT; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 19; INTERLEUKIN 1BETA; INTERLEUKIN 20; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; OSTEOCLAST DIFFERENTIATION FACTOR; PAMIDRONIC ACID; PREDNISOLONE; RANTES; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SALAZOSULFAPYRIDINE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR; UNINDEXED DRUG; CYTOKINE;

EID: 84994383085     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.160256     Document Type: Review
Times cited : (82)

References (60)
  • 1
    • 84882284037 scopus 로고    scopus 로고
    • Monogenic autoinflammatory diseases: Concept and clinical manifestations
    • Almeida de Jesus A, Goldbach-Mansky R. Monogenic autoinflammatory diseases: concept and clinical manifestations. Clin Immunol 2013;147:155-74.
    • (2013) Clin Immunol , vol.147 , pp. 155-174
    • Almeida De Jesus, A.1    Goldbach-Mansky, R.2
  • 2
    • 0033515520 scopus 로고    scopus 로고
    • Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
    • McDermott MF, Aksentijevich I, Galon J, McDermott EM, Ogunkolade BW, Centola M, et al. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell 1999;97:133-44.
    • (1999) Cell , vol.97 , pp. 133-144
    • McDermott, M.F.1    Aksentijevich, I.2    Galon, J.3    McDermott, E.M.4    Ogunkolade, B.W.5    Centola, M.6
  • 4
    • 84881484265 scopus 로고    scopus 로고
    • Autoinflammatory bone disorders: Update on immunologic abnormalities and clues about possible triggers
    • Sharma M, Ferguson PJ. Autoinflammatory bone disorders: update on immunologic abnormalities and clues about possible triggers. Curr Opin Rheumatol 2013;25:658-64.
    • (2013) Curr Opin Rheumatol , vol.25 , pp. 658-664
    • Sharma, M.1    Ferguson, P.J.2
  • 5
    • 84891662713 scopus 로고    scopus 로고
    • A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field
    • Hedrich CM, Hahn G, Girschick HJ, Morbach H. A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field. Expert Rev Clin Immunol 2013;9:845-54.
    • (2013) Expert Rev Clin Immunol , vol.9 , pp. 845-854
    • Hedrich, C.M.1    Hahn, G.2    Girschick, H.J.3    Morbach, H.4
  • 8
    • 84878638609 scopus 로고    scopus 로고
    • New directions in management of SAPHO syndrome
    • Assmann G. New directions in management of SAPHO syndrome. Curr Rheumatol Rev 2013;9:1.
    • (2013) Curr Rheumatol Rev , vol.9 , pp. 1
    • Assmann, G.1
  • 10
    • 79960104753 scopus 로고    scopus 로고
    • Nonbacterial osteitis in children: Data of a German Incidence Surveillance Study
    • ESPED Study Group
    • Jansson AF, Grote V; ESPED Study Group. Nonbacterial osteitis in children: data of a German Incidence Surveillance Study. Acta Paediatr 2011;100:1150-7.
    • (2011) Acta Paediatr , vol.100 , pp. 1150-1157
    • Jansson, A.F.1    Grote, V.2
  • 13
    • 34548448934 scopus 로고    scopus 로고
    • Chronic recurrent multifocal osteomyelitis: A concise review and genetic update
    • El-Shanti HI, Ferguson PJ. Chronic recurrent multifocal osteomyelitis: a concise review and genetic update. Clin Orthop Relat Res 2007;462:11-9.
    • (2007) Clin Orthop Relat Res , vol.462 , pp. 11-19
    • El-Shanti, H.I.1    Ferguson, P.J.2
  • 14
    • 84865459912 scopus 로고    scopus 로고
    • Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression
    • Hofmann SR, Morbach H, Schwarz T, Rosen-Wolff A, Girschick HJ, Hedrich CM. Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression. Clin Immunol 2012;145:69-76.
    • (2012) Clin Immunol , vol.145 , pp. 69-76
    • Hofmann, S.R.1    Morbach, H.2    Schwarz, T.3    Rosen-Wolff, A.4    Girschick, H.J.5    Hedrich, C.M.6
  • 15
    • 81355148841 scopus 로고    scopus 로고
    • Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression
    • Hofmann SR, Schwarz T, Möller JC, Morbach H, Schnabel A, Rosen-Wolff A, et al. Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression. Clin Immunol 2011;141:317-27.
    • (2011) Clin Immunol , vol.141 , pp. 317-327
    • Hofmann, S.R.1    Schwarz, T.2    Möller, J.C.3    Morbach, H.4    Schnabel, A.5    Rosen-Wolff, A.6
  • 16
    • 0141956455 scopus 로고    scopus 로고
    • Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1
    • Asumalahti K, Laitinen T, Lahermo P, Suomela S, Itkonen-Vatjus R, Jansen C, et al. Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1. J Invest Dermatol 2003;121:735-40.
    • (2003) J Invest Dermatol , vol.121 , pp. 735-740
    • Asumalahti, K.1    Laitinen, T.2    Lahermo, P.3    Suomela, S.4    Itkonen-Vatjus, R.5    Jansen, C.6
  • 17
    • 29344448820 scopus 로고    scopus 로고
    • A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis
    • Ferguson PJ, Bing X, Vasef MA, Ochoa LA, Mahgoub A, Waldschmidt TJ, et al. A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis. Bone 2006;38:41-7.
    • (2006) Bone , vol.38 , pp. 41-47
    • Ferguson, P.J.1    Bing, X.2    Vasef, M.A.3    Ochoa, L.A.4    Mahgoub, A.5    Waldschmidt, T.J.6
  • 18
    • 22244469461 scopus 로고    scopus 로고
    • Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome)
    • Ferguson PJ, Chen S, Tayeh MK, Ochoa L, Leal SM, Pelet A, et al. Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome). J Med Genet 2005;42:551-7.
    • (2005) J Med Genet , vol.42 , pp. 551-557
    • Ferguson, P.J.1    Chen, S.2    Tayeh, M.K.3    Ochoa, L.4    Leal, S.M.5    Pelet, A.6
  • 20
    • 84859514658 scopus 로고    scopus 로고
    • Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages
    • Valdearcos M, Esquinas E, Meana C, Peña L, Gil-de-Gómez L, Balsinde J, et al. Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages. J Biol Chem 2012;287:10894-904.
    • (2012) J Biol Chem , vol.287 , pp. 10894-10904
    • Valdearcos, M.1    Esquinas, E.2    Meana, C.3    Peña, L.4    Gil-De-Gómez, L.5    Balsinde, J.6
  • 21
    • 2442684327 scopus 로고    scopus 로고
    • Rituximab inhibits p38 MAPK activity in 2F7 B NHL and decreases IL-10 transcription: Pivotal role of p38 MAPK in drug resistance
    • Vega MI, Huerta-Yepaz S, Garban H, Jazirehi A, Emmanouilides C, Bonavida B. Rituximab inhibits p38 MAPK activity in 2F7 B NHL and decreases IL-10 transcription: pivotal role of p38 MAPK in drug resistance. Oncogene 2004;23:3530-40.
    • (2004) Oncogene , vol.23 , pp. 3530-3540
    • Vega, M.I.1    Huerta-Yepaz, S.2    Garban, H.3    Jazirehi, A.4    Emmanouilides, C.5    Bonavida, B.6
  • 23
    • 77951025174 scopus 로고    scopus 로고
    • Association of chronic non-bacterial osteomyelitis with Crohn's disease but not with CARD15 gene variants
    • Morbach H, Dick A, Beck C, Stenzel M, Muller-Hermelink HK, Raab P, et al. Association of chronic non-bacterial osteomyelitis with Crohn's disease but not with CARD15 gene variants. Rheumatol Int 2010;30:617-21.
    • (2010) Rheumatol Int , vol.30 , pp. 617-621
    • Morbach, H.1    Dick, A.2    Beck, C.3    Stenzel, M.4    Muller-Hermelink, H.K.5    Raab, P.6
  • 24
    • 66649113371 scopus 로고    scopus 로고
    • An autoinflammatory disease due to homozygous deletion of the IL1RN locus
    • Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, et al. An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N Engl J Med 2009;360:2438-44.
    • (2009) N Engl J Med , vol.360 , pp. 2438-2444
    • Reddy, S.1    Jia, S.2    Geoffrey, R.3    Lorier, R.4    Suchi, M.5    Broeckel, U.6
  • 25
    • 0030804743 scopus 로고    scopus 로고
    • A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome
    • Lindor NM, Arsenault TM, Solomon H, Seidman CE, McEvoy MT. A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome. Mayo Clin Proc 1997;72:611-5.
    • (1997) Mayo Clin Proc , vol.72 , pp. 611-615
    • Lindor, N.M.1    Arsenault, T.M.2    Solomon, H.3    Seidman, C.E.4    McEvoy, M.T.5
  • 26
    • 78650006414 scopus 로고    scopus 로고
    • Clinical, molecular, and genetic characteristics of PAPA syndrome: A review
    • Smith EJ, Allantaz F, Bennett L, Zhang D, Gao X, Wood G, et al. Clinical, molecular, and genetic characteristics of PAPA syndrome: a review. Curr Genomics 2010;11:519-27.
    • (2010) Curr Genomics , vol.11 , pp. 519-527
    • Smith, E.J.1    Allantaz, F.2    Bennett, L.3    Zhang, D.4    Gao, X.5    Wood, G.6
  • 27
    • 0037091012 scopus 로고    scopus 로고
    • Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
    • Wise CA, Gillum JD, Seidman CE, Lindor NM, Veile R, Bashiardes S, et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet 2002;11:961-9.
    • (2002) Hum Mol Genet , vol.11 , pp. 961-969
    • Wise, C.A.1    Gillum, J.D.2    Seidman, C.E.3    Lindor, N.M.4    Veile, R.5    Bashiardes, S.6
  • 29
    • 33845594483 scopus 로고    scopus 로고
    • Classification of non-bacterial osteitis: Retrospective study of clinical, immunological and genetic aspects in 89 patients
    • Jansson A, Renner ED, Ramser J, Mayer A, Haban M, Meindl A, et al. Classification of non-bacterial osteitis: retrospective study of clinical, immunological and genetic aspects in 89 patients. Rheumatology 2007;46:154-60.
    • (2007) Rheumatology , vol.46 , pp. 154-160
    • Jansson, A.1    Renner, E.D.2    Ramser, J.3    Mayer, A.4    Haban, M.5    Meindl, A.6
  • 30
    • 84961798934 scopus 로고    scopus 로고
    • Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO)
    • Hofmann SR, Kubasch AS, Range U, Laass MW, Morbach H, Girschick HJ, et al. Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO). Rheumatol Int 2016;36:769-79.
    • (2016) Rheumatol Int , vol.36 , pp. 769-779
    • Hofmann, S.R.1    Kubasch, A.S.2    Range, U.3    Laass, M.W.4    Morbach, H.5    Girschick, H.J.6
  • 31
    • 85047695184 scopus 로고    scopus 로고
    • Chronic recurrent multifocal osteomyelitis (CRMO): Evidence for a susceptibility gene located on chromosome 18q21.3-18q22
    • Golla A, Jansson A, Ramser J, Hellebrand H, Zahn R, Meitinger T, et al. Chronic recurrent multifocal osteomyelitis (CRMO): evidence for a susceptibility gene located on chromosome 18q21.3-18q22. Eur J Hum Genet 2002;10:217-21.
    • (2002) Eur J Hum Genet , vol.10 , pp. 217-221
    • Golla, A.1    Jansson, A.2    Ramser, J.3    Hellebrand, H.4    Zahn, R.5    Meitinger, T.6
  • 32
    • 84857606314 scopus 로고    scopus 로고
    • Mutation screening of the IL-1 receptor antagonist gene in chronic non-bacterial osteomyelitis of childhood and adolescence
    • Beck C, Girschick HJ, Morbach H, Schwarz T, Yimam T, Frenkel J, et al. Mutation screening of the IL-1 receptor antagonist gene in chronic non-bacterial osteomyelitis of childhood and adolescence. Clin Exp Rheumatol 2011;29:1040-3.
    • (2011) Clin Exp Rheumatol , vol.29 , pp. 1040-1043
    • Beck, C.1    Girschick, H.J.2    Morbach, H.3    Schwarz, T.4    Yimam, T.5    Frenkel, J.6
  • 33
    • 76649085191 scopus 로고    scopus 로고
    • Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: A study of PSTPIP2, NOD2, and LPIN2 genes
    • Hurtado-Nedelec M, Chollet-Martin S, Chapeton D, Hugot JP, Hayem G, Gérard B. Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: a study of PSTPIP2, NOD2, and LPIN2 genes. J Rheumatol 2010;37:401-9.
    • (2010) J Rheumatol , vol.37 , pp. 401-409
    • Hurtado-Nedelec, M.1    Chollet-Martin, S.2    Chapeton, D.3    Hugot, J.P.4    Hayem, G.5    Gérard, B.6
  • 34
    • 84857055326 scopus 로고    scopus 로고
    • Pilot study: Possible association of IL10 promoter polymorphisms with CRMO
    • Hamel J, Paul D, Gahr M, Hedrich CM. Pilot study: possible association of IL10 promoter polymorphisms with CRMO. Rheumatol Int 2012;32:555-6.
    • (2012) Rheumatol Int , vol.32 , pp. 555-556
    • Hamel, J.1    Paul, D.2    Gahr, M.3    Hedrich, C.M.4
  • 35
    • 77953957751 scopus 로고    scopus 로고
    • Cell type-specific regulation of IL-10 expression in inflammation and disease
    • Hedrich CM, Bream JH. Cell type-specific regulation of IL-10 expression in inflammation and disease. Immunol Res 2010; 47:185-206.
    • (2010) Immunol Res , vol.47 , pp. 185-206
    • Hedrich, C.M.1    Bream, J.H.2
  • 36
    • 84859777122 scopus 로고    scopus 로고
    • Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury
    • Hofmann SR, Rosen-Wolff A, Tsokos GC, Hedrich CM. Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury. Clin Immunol 2012;143:116-27.
    • (2012) Clin Immunol , vol.143 , pp. 116-127
    • Hofmann, S.R.1    Rosen-Wolff, A.2    Tsokos, G.C.3    Hedrich, C.M.4
  • 37
    • 84943523723 scopus 로고    scopus 로고
    • Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1? Expression and release
    • Hofmann SR, Kubasch AS, Ioannidis C, Rösen-Wolff A, Girschick HJ, Morbach H, et al. Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1? expression and release. Clin Immunol 2015;161:300-7.
    • (2015) Clin Immunol , vol.161 , pp. 300-307
    • Hofmann, S.R.1    Kubasch, A.S.2    Ioannidis, C.3    Rösen-Wolff, A.4    Girschick, H.J.5    Morbach, H.6
  • 39
    • 70349987611 scopus 로고    scopus 로고
    • Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways
    • Grange PA, Raingeaud J, Calvez V, Dupin N. Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways. J Dermatol Sci 2009;56:106-12.
    • (2009) J Dermatol Sci , vol.56 , pp. 106-112
    • Grange, P.A.1    Raingeaud, J.2    Calvez, V.3    Dupin, N.4
  • 40
    • 69249229479 scopus 로고    scopus 로고
    • Osteoimmunology: Crosstalk between the immune and bone systems
    • Nakashima T, Takayanagi H. Osteoimmunology: crosstalk between the immune and bone systems. J Clin Immunol 2009;29:555-67.
    • (2009) J Clin Immunol , vol.29 , pp. 555-567
    • Nakashima, T.1    Takayanagi, H.2
  • 45
    • 84946483084 scopus 로고    scopus 로고
    • The immunogenetics of psoriasis: A comprehensive review
    • Harden JL, Krueger JG, Bowcock AM. The immunogenetics of psoriasis: a comprehensive review. J Autoimmun 2015;64:66-73.
    • (2015) J Autoimmun , vol.64 , pp. 66-73
    • Harden, J.L.1    Krueger, J.G.2    Bowcock, A.M.3
  • 46
    • 84960426342 scopus 로고    scopus 로고
    • Shaping the spectrum-from autoinflammation to autoimmunity
    • Hedrich CM. Shaping the spectrum-from autoinflammation to autoimmunity. Clin Immunol 2016;165:21-8.
    • (2016) Clin Immunol , vol.165 , pp. 21-28
    • Hedrich, C.M.1
  • 48
    • 77951575415 scopus 로고    scopus 로고
    • Chronic nonbacterial osteomyelitis in childhood: Prospective follow-up during the first year of anti-inflammatory treatment
    • Beck C, Morbach H, Beer M, Stenzel M, Tappe D, Gattenlöhner S, et al. Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment. Arthritis Res Ther 2010;12:R74.
    • (2010) Arthritis Res Ther , vol.12 , pp. R74
    • Beck, C.1    Morbach, H.2    Beer, M.3    Stenzel, M.4    Tappe, D.5    Gattenlöhner, S.6
  • 49
    • 62849112761 scopus 로고    scopus 로고
    • In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation
    • Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation. PLoS One 2009;4:e4706.
    • (2009) PLoS One , vol.4 , pp. e4706
    • Foteinou, P.T.1    Calvano, S.E.2    Lowry, S.F.3    Androulakis, I.P.4
  • 50
    • 67349088364 scopus 로고    scopus 로고
    • The use of corticosteroids and nonsteroidal antiinflammatory medication for the management of pain and inflammation after third molar surgery: A review of the literature
    • Kim K, Brar P, Jakubowski J, Kaltman S, Lopez E. The use of corticosteroids and nonsteroidal antiinflammatory medication for the management of pain and inflammation after third molar surgery: a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107:630-40.
    • (2009) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.107 , pp. 630-640
    • Kim, K.1    Brar, P.2    Jakubowski, J.3    Kaltman, S.4    Lopez, E.5
  • 51
    • 77956339258 scopus 로고    scopus 로고
    • Methotrexate in the therapy of juvenile idiopathic arthritis
    • Holzinger D, Frosch M, Föll D. [Methotrexate in the therapy of juvenile idiopathic arthritis]. [Article in German] Z Rheumatol 2010;69:496-504.
    • (2010) Article in German Z Rheumatol , vol.69 , pp. 496-504
    • Holzinger, D.1    Frosch, M.2    Föll, D.3
  • 52
    • 79952112332 scopus 로고    scopus 로고
    • Spinal involvement in chronic recurrent multifocal osteomyelitis (CRMO) in childhood and effect of pamidronate
    • Hospach T, Langendoerfer M, von Kalle T, Maier J, Dannecker GE. Spinal involvement in chronic recurrent multifocal osteomyelitis (CRMO) in childhood and effect of pamidronate. Eur J Pediatr 2010;169:1105-11.
    • (2010) Eur J Pediatr , vol.169 , pp. 1105-1111
    • Hospach, T.1    Langendoerfer, M.2    Von Kalle, T.3    Maier, J.4    Dannecker, G.E.5
  • 53
    • 60649093718 scopus 로고    scopus 로고
    • Dramatic pain relief and resolution of bone inflammation following pamidronate in 9 pediatric patients with persistent chronic recurrent multifocal osteomyelitis (CRMO)
    • Miettunen PM, Wei X, Kaura D, Reslan WA, Aguirre AN, Kellner JD. Dramatic pain relief and resolution of bone inflammation following pamidronate in 9 pediatric patients with persistent chronic recurrent multifocal osteomyelitis (CRMO). Pediatr Rheumatol Online J 2009;7:2.
    • (2009) Pediatr Rheumatol Online J , vol.7 , pp. 2
    • Miettunen, P.M.1    Wei, X.2    Kaura, D.3    Reslan, W.A.4    Aguirre, A.N.5    Kellner, J.D.6
  • 54
    • 84867803403 scopus 로고    scopus 로고
    • PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts
    • Chitu V, Nacu V, Charles JF, Henne WM, McMahon HT, Nandi S, et al. PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts. Blood 2012;120:3126-35.
    • (2012) Blood , vol.120 , pp. 3126-3135
    • Chitu, V.1    Nacu, V.2    Charles, J.F.3    Henne, W.M.4    McMahon, H.T.5    Nandi, S.6
  • 55
    • 33645734214 scopus 로고    scopus 로고
    • Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease
    • Grosse J, Chitu V, Marquardt A, Hanke P, Schmittwolf C, Zeitlmann L, et al. Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood 2006;107:3350-8.
    • (2006) Blood , vol.107 , pp. 3350-3358
    • Grosse, J.1    Chitu, V.2    Marquardt, A.3    Hanke, P.4    Schmittwolf, C.5    Zeitlmann, L.6
  • 58
    • 84943365345 scopus 로고    scopus 로고
    • New discoveries in CRMO: IL-1?, the neutrophil, and the microbiome implicated in disease pathogenesis in Pstpip2-deficient mice
    • Ferguson PJ, Laxer RM. New discoveries in CRMO: IL-1?, the neutrophil, and the microbiome implicated in disease pathogenesis in Pstpip2-deficient mice. Semin Immunopathol 2015;37:407-12.
    • (2015) Semin Immunopathol , vol.37 , pp. 407-412
    • Ferguson, P.J.1    Laxer, R.M.2
  • 59
    • 84910014443 scopus 로고    scopus 로고
    • Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction
    • Greenhill CJ, Jones GW, Nowell MA, Newton Z, Harvey AK, Moideen AN, et al. Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Res Ther 2014;16:419.
    • (2014) Arthritis Res Ther , vol.16 , pp. 419
    • Greenhill, C.J.1    Jones, G.W.2    Nowell, M.A.3    Newton, Z.4    Harvey, A.K.5    Moideen, A.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.