Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release

Clinical Immunology

Volumn 161, Issue 2, 2015, Pages 300-307

  Hofmann, S R ^a   Kubasch, A S ^a   Ioannidis, C ^b   Rosen Wolff A ^a   Girschick, H J ^c   Morbach, H ^d   Hedrich, C M ^a,b  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Children's Hospital   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Bone; CNO; CRMO; Cytokine; IL 10; Inflammasome; Inflammation

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 19; INTERLEUKIN 1BETA; INTERLEUKIN 20; TRANSCRIPTION FACTOR SP1; CARRIER PROTEIN; IL19 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; NLRP3 PROTEIN, HUMAN;

ARTICLE; CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; INFLAMMATION; MAJOR CLINICAL STUDY; MONOCYTE; OSTEOLYSIS; OSTEOMYELITIS; PRIORITY JOURNAL; RECURRENT DISEASE; CELL CULTURE; CHILD; DNA METHYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE;

CARRIER PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; CHILD; DNA METHYLATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; INFLAMMASOMES; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKINS; MONOCYTES; OSTEOMYELITIS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SP1 TRANSCRIPTION FACTOR;

EID: 84943523723     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.09.013     Document Type: Article

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