Neural tube morphogenesis in synthetic 3D microenvironments

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 44, 2016, Pages E6831-E6839

  Ranga, Adrian ^a,c   Girgin, Mehmet ^a   Meinhardt, Andrea ^b   Eberle, Dominic ^b   Caiazzo, Massimiliano ^a,d   Tanaka, Elly M ^b   Lutolf, Matthias P ^a  

^a EPFL   (Switzerland)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

Author keywords

Development; Embryonic stem cell; Extracellular matrix; Neural tube; Organoid

Indexed keywords

COLLAGEN TYPE 4; MACROGOL; MATRIGEL; PERLECAN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; BIODEGRADABILITY; CELL DIFFERENTIATION; CELL DIVISION; CELL FATE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; DISEASE MODEL; EXTRACELLULAR MATRIX; IN VITRO STUDY; MOLECULAR MODEL; MORPHOGENESIS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; RIGIDITY; SYNTHETIC BIOLOGY; TISSUE STRUCTURE;

EID: 84994275774     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1603529113     Document Type: Article

References (32)

1. Kojima Y, Tam OH, Tam PP (2014) Timing of developmental events in the early mouse embryo. Semin Cell Dev Biol 34: 65-75.
2. Eyckmans J, Boudou T, Yu X, Chen CS (2011) A hitchhiker's guide to mechanobiology. Dev Cell 21(1): 35-47.
3. Stern CD, Fraser SE (2001) Tracing the lineage of tracing cell lineages. Nat Cell Biol 3(9): E216-E218.
4. De Robertis EM (2006) Spemann's organizer and self-regulation in amphibian embryos. Nat Rev Mol Cell Biol 7(4): 296-302.
5. Sato T, et al. (2009) Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459(7244): 262-265.
6. Takebe T, et al. (2013) Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 499(7459): 481-484.
7. Lancaster MA, et al. (2013) Cerebral organoids model human brain development and microcephaly. Nature 501(7467): 373-379.
8. Meinhardt A, et al. (2014) 3D reconstitution of the patterned neural tube from embryonic stem cells. Stem Cell Rep 3(6): 987-999.
9. Langer R, Tirrell DA (2004) Designing materials for biology and medicine. Nature 428(6982): 487-492.
10. Lutolf MP, Gilbert PM, Blau HM (2009) Designing materials to direct stem-cell fate. Nature 462(7272): 433-441.
11. Griffith LG, Swartz MA (2006) Capturing complex 3D tissue physiology in vitro. Nat Rev Mol Cell Biol 7(3): 211-224.
12. Dolatshahi-Pirouz A, et al. (2014) A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Sci Rep 4: 3896.
13. Nii M, et al. (2013) The effects of interactive mechanical and biochemical niche signaling on osteogenic differentiation of adipose-derived stem cells using combinatorial hydrogels. Acta Biomater 9(3): 5475-5483.
14. Ehrbar M, et al. (2007) Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering. Biomaterials 28(26): 3856-3866.
15. Ehrbar M, et al. (2007) Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules 8(10): 3000-3007.
16. Ranga A, et al. (2014) 3D niche microarrays for systems-level analyses of cell fate. Nat Commun 5: 4324.
17. Enemchukwu NO, et al. (2016) Syntheticmatrices reveal contributions of ECMbiophysical and biochemical properties to epithelial morphogenesis. J Cell Biol 212(1): 113-124.
18. Chung IM, et al. (2008) Bioadhesive hydrogel microenvironments to modulate epithelial morphogenesis. Biomaterials 29(17): 2637-2645.
19. Gouti M, et al. (2014) In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol 12(8): E1001937.
20. Ying QL, Stavridis M, Griffiths D, Li M, Smith A (2003) Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21(2): 183-186.
21. Bryant DM, Mostov KE (2008) From cells to organs: Building polarized tissue. Nat Rev Mol Cell Biol 9(11): 887-901.
22. Lippmann ES, et al. (2015) Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm. Stem Cell Rep 4(4): 632-644.
23. Ribes V, Le Roux I, Rhinn M, Schuhbaur B, Dollé P (2009) Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways. Development 136(4): 665-676.
24. Zegers MM, O'Brien LE, Yu W, Datta A, Mostov KE (2003) Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol 13(4): 169-176.
25. Pereira C, Araújo F, Barrias CC, Granja PL, Sarmento B (2015) Dissecting stromal-epithelial interactions in a 3D in vitro cellularized intestinal model for permeability studies. Biomaterials 56: 36-45.
26. Bissell MJ, Rizki A, Mian IS (2003) Tissue architecture: The ultimate regulator of breast epithelial function. Curr Opin Cell Biol 15(6): 753-762.
27. Bedzhov I, Zernicka-Goetz M (2014) Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation. Cell 156(5): 1032-1044.
28. Yu W, et al. (2008) Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Rep 9(9): 923-929.
29. Priya R, et al. (2015) Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol 17(10): 1282-1293.
30. YuW, et al. (2005) Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol Biol Cell 16(2): 433-445.
31. O'Brien LE, et al. (2001) Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nat Cell Biol 3(9): 831-838.
32. Lukinavicius G, et al. (2014) Fluorogenic probes for live-cell imaging of the cytoskeleton. Nature Methods 11: 731-733.