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Volumn 7, Issue 4, 2006, Pages 296-302

Spemann's organizer and self-regulation in amphibian embryos

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; GROWTH FACTOR; PROTEINASE INHIBITOR;

EID: 33645785590     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm1855     Document Type: Review
Times cited : (219)

References (60)
  • 2
    • 9544247527 scopus 로고
    • Half embryos and whole embryos from one of the first two blastomeres
    • Morgan, T. H. Half embryos and whole embryos from one of the first two blastomeres. Anat. Anz. 10, 623-638 (1895).
    • (1895) Anat. Anz. , vol.10 , pp. 623-638
    • Morgan, T.H.1
  • 3
    • 0001637658 scopus 로고
    • Experiments on the development of the fore-limb of Amblystoma, a self-differentiating equipotential system
    • Harrison, R. G. Experiments on the development of the fore-limb of Amblystoma, a self-differentiating equipotential system. J. Exp. Zool. 25, 413-461 (1918).
    • (1918) J. Exp. Zool. , vol.25 , pp. 413-461
    • Harrison, R.G.1
  • 4
    • 8444229587 scopus 로고    scopus 로고
    • Stern, C. D. (ed.) Cold Spring Harbor Laboratory, New York
    • Stern, C. D. (ed.) Gastrulation (Cold Spring Harbor Laboratory, New York, 2004).
    • (2004) Gastrulation
  • 5
    • 34347159966 scopus 로고
    • Induction of embryonic primordia by implantation of organizers from a different species
    • Spemann, H. & Mangold, H. Induction of embryonic primordia by implantation of organizers from a different species. Roux's Arch. Entw. Mech. 100, 599-638 (1924).
    • (1924) Roux's Arch. Entw. Mech. , vol.100 , pp. 599-638
    • Spemann, H.1    Mangold, H.2
  • 7
    • 0021141441 scopus 로고
    • Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes
    • Carrasco, A. E., McGinnis, W., Gehring, W. J. & De Robertis, E. M. Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes. Cell 37, 409-414 (1984).
    • (1984) Cell , vol.37 , pp. 409-414
    • Carrasco, A.E.1    McGinnis, W.2    Gehring, W.J.3    De Robertis, E.M.4
  • 8
    • 0026342562 scopus 로고
    • Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid
    • Cho, K. W. Y., Blumberg, B., Steinbeisser, H. & De Robertis, E. M. Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid.Cell 67, 1111-1120 (1991).
    • (1991) Cell , vol.67 , pp. 1111-1120
    • Cho, K.W.Y.1    Blumberg, B.2    Steinbeisser, H.3    De Robertis, E.M.4
  • 9
    • 0026576607 scopus 로고
    • The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos
    • Taira, M., Jamrich, M., Good, P. J. & Dawid, I. B. The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. Genes Dev. 6, 356-366 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 356-366
    • Taira, M.1    Jamrich, M.2    Good, P.J.3    Dawid, I.B.4
  • 10
    • 0026530072 scopus 로고
    • A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain
    • Dirksen, M. L. & Jamrich, M. A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain. Genes Dev. 6, 599-608 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 599-608
    • Dirksen, M.L.1    Jamrich, M.2
  • 11
    • 0027394583 scopus 로고
    • The homeobox gene goosecoid controls cell migration in Xenopus embryos
    • Niehrs, C., Keller, R., Cho, K. W. Y. & De Robertis, E. M. The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72, 491-503 (1993).
    • (1993) Cell , vol.72 , pp. 491-503
    • Niehrs, C.1    Keller, R.2    Cho, K.W.Y.3    De Robertis, E.M.4
  • 12
    • 0027967380 scopus 로고
    • Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
    • Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. & De Robertis, E. M. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790 (1994).
    • (1994) Cell , vol.79 , pp. 779-790
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    Geissert, D.4    Gont, L.K.5    De Robertis, E.M.6
  • 13
    • 33847250487 scopus 로고    scopus 로고
    • Stern, C. D. ed. Cold Spring Harbor Laboratory, New York
    • De Robertis, E. M. in Gastrulation (Stern, C. D. ed.) 581-589 (Cold Spring Harbor Laboratory, New York, 2004).
    • (2004) Gastrulation , pp. 581-589
    • De Robertis, E.M.1
  • 14
    • 0026646326 scopus 로고
    • Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
    • Smith, W. C. & Harland, R. M. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840 (1992).
    • (1992) Cell , vol.70 , pp. 829-840
    • Smith, W.C.1    Harland, R.M.2
  • 16
    • 0027381943 scopus 로고
    • Neural induction by secreted polypeptide noggin
    • Lamb, T. M. et al. Neural induction by secreted polypeptide noggin. Science 262, 713-718 (1993).
    • (1993) Science , vol.262 , pp. 713-718
    • Lamb, T.M.1
  • 17
    • 0028270311 scopus 로고
    • Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity
    • Hemmati-Brivanlou, A., Kelly, O. G. & Melton, D. A. Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295 (1994).
    • (1994) Cell , vol.77 , pp. 283-295
    • Hemmati-Brivanlou, A.1    Kelly, O.G.2    Melton, D.A.3
  • 18
    • 0034574602 scopus 로고    scopus 로고
    • The establishment of Spemann's organizer and patterning of the vertebrate embryo
    • De Robertis, E. M., Larraín, J., Oelgeschläger, M. & Wessely, O. The establishment of Spemann's organizer and patterning of the vertebrate embryo. Nature Rev. Genet. 1, 171-181 (2000).
    • (2000) Nature Rev. Genet. , vol.1 , pp. 171-181
    • De Robertis, E.M.1    Larraín, J.2    Oelgeschläger, M.3    Wessely, O.4
  • 19
    • 8444237836 scopus 로고    scopus 로고
    • Dorsal-ventral patterning and neural induction in Xenopus embryos
    • De Robertis, E. M. & Kuroda, H. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annu. Rev. Cell Dev. Biol. 20, 285-308 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 285-308
    • De Robertis, E.M.1    Kuroda, H.2
  • 20
    • 0029617936 scopus 로고
    • Anti-dorsalizing morphogenetic protein is a novel TGF-β homolog expressed in the Spemann organizer
    • Moos, M. Jr., Wang, S. & Krinks, M. Anti-dorsalizing morphogenetic protein is a novel TGF-β homolog expressed in the Spemann organizer. Development 121, 4293-4301 (1995).
    • (1995) Development , vol.121 , pp. 4293-4301
    • Moos Jr., M.1    Wang, S.2    Krinks, M.3
  • 21
    • 0033986567 scopus 로고    scopus 로고
    • Requirement for anti-dorsalizing morphogenetic protein in organizer patterning
    • Dosch, R. & Niehrs, C. Requirement for anti-dorsalizing morphogenetic protein in organizer patterning. Mech. Dev. 90, 195-203 (2000).
    • (2000) Mech. Dev. , vol.90 , pp. 195-203
    • Dosch, R.1    Niehrs, C.2
  • 22
    • 0033518256 scopus 로고    scopus 로고
    • Synexpression groups in eukaryotes
    • Niehrs, C. & Pollet, N. Synexpression groups in eukaryotes. Nature 402, 483-487 (1999).
    • (1999) Nature , vol.402 , pp. 483-487
    • Niehrs, C.1    Pollet, N.2
  • 23
    • 34250959842 scopus 로고
    • Versuche zur Analyse der Induktionsmittel in der Embryonalentwicklung
    • Bautzman, H., Holtfreter, J., Spemann, H. & Mangold, O. Versuche zur Analyse der Induktionsmittel in der Embryonalentwicklung. Naturwissenschaften 20, 971-974 (1932).
    • (1932) Naturwissenschaften , vol.20 , pp. 971-974
    • Bautzman, H.1    Holtfreter, J.2    Spemann, H.3    Mangold, O.4
  • 24
    • 0001891022 scopus 로고
    • Willier, B. H., Weiss, P. A. & Hamburger, V. eds W. B. Saunders, Philadelphia
    • Holtfreter, J. & Hamburger, V. in Analysis of Development (Willier, B. H., Weiss, P. A. & Hamburger, V. eds) 230-296 (W. B. Saunders, Philadelphia, 1955).
    • (1955) Analysis of Development , pp. 230-296
    • Holtfreter, J.1    Hamburger, V.2
  • 25
    • 84982340583 scopus 로고
    • Neural diffferentiation without organizer
    • Barth, L. G. Neural diffferentiation without organizer. J. Exp. Zool. 87, 371-384 (1941).
    • (1941) J. Exp. Zool. , vol.87 , pp. 371-384
    • Barth, L.G.1
  • 26
    • 84982071036 scopus 로고
    • Neural differentiation of ectoderm through exposure to saline solution
    • Holtfreter, J. Neural differentiation of ectoderm through exposure to saline solution. J. Exp. Zool. 95, 307-343 (1944).
    • (1944) J. Exp. Zool. , vol.95 , pp. 307-343
    • Holtfreter, J.1
  • 27
    • 0029009530 scopus 로고
    • Regulation of neural induction by the end and BMP-4 antagonistic patterning signals in Xenopus
    • Sasai, Y., Lu, B., Steinbeisser, H. & De Robertis, E. M. Regulation of neural induction by the end and BMP-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336 (1995).
    • (1995) Nature , vol.376 , pp. 333-336
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    De Robertis, E.M.4
  • 28
    • 0030598867 scopus 로고    scopus 로고
    • Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of Chordin to BMP-4
    • Piccolo, S., Sasai, Y., Lu, B. & De Robertis, E. M. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of Chordin to BMP-4. Cell 86, 589-598 (1996).
    • (1996) Cell , vol.86 , pp. 589-598
    • Piccolo, S.1    Sasai, Y.2    Lu, B.3    De Robertis, E.M.4
  • 29
    • 0030598829 scopus 로고    scopus 로고
    • The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
    • Zimmerman, L. B., De Jesús-Escobar, J. M. & Harland, R. M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606 (1996).
    • (1996) Cell , vol.86 , pp. 599-606
    • Zimmerman, L.B.1    De Jesús-Escobar, J.M.2    Harland, R.M.3
  • 30
    • 26444515002 scopus 로고    scopus 로고
    • The structure of the follistatin:activin complex reveals antagonism of both Type I and Type II receptor binding
    • Thompson, T. B., Lerch, T. F., Cook, R. W., Woodruff, T. K. & Jardetzky, T. S. The structure of the follistatin:activin complex reveals antagonism of both Type I and Type II receptor binding. Dev. Cell 9, 535-543 (2005).
    • (2005) Dev. Cell , vol.9 , pp. 535-543
    • Thompson, T.B.1    Lerch, T.F.2    Cook, R.W.3    Woodruff, T.K.4    Jardetzky, T.S.5
  • 31
    • 0037086052 scopus 로고    scopus 로고
    • Morpholino oligos: Making sense of antisense?
    • Heasman, J. Morpholino oligos: making sense of antisense? Dev. Biol. 243, 209-214 (2002).
    • (2002) Dev. Biol. , vol.243 , pp. 209-214
    • Heasman, J.1
  • 32
    • 0037321789 scopus 로고    scopus 로고
    • Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos
    • Oelgeschläger, M., Kuroda, H., Reversade, B. & De Robertis, E. M. Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Dev. Cell 4, 219-230 (2003).
    • (2003) Dev. Cell , vol.4 , pp. 219-230
    • Oelgeschläger, M.1    Kuroda, H.2    Reversade, B.3    De Robertis, E.M.4
  • 33
    • 0034628534 scopus 로고    scopus 로고
    • The organizer secreted factors Chordin and Noggin are required for forebrain development in the mouse
    • Bachiller, D. et al. The organizer secreted factors Chordin and Noggin are required for forebrain development in the mouse. Nature 403, 658-661 (2000).
    • (2000) Nature , vol.403 , pp. 658-661
    • Bachiller, D.1
  • 34
    • 14644427197 scopus 로고    scopus 로고
    • Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures
    • Khokha, M. K., Yeh, J., Grammer, T. C. & Harland, R. M. Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. Dev. Cell 8, 401-411 (2005).
    • (2005) Dev. Cell , vol.8 , pp. 401-411
    • Khokha, M.K.1    Yeh, J.2    Grammer, T.C.3    Harland, R.M.4
  • 35
    • 19244387468 scopus 로고    scopus 로고
    • Neural induction in Xenopus: Requirement for ectodermal and endomesodermal signals via Chordin, Noggin, β-catenin, and Cerberus
    • Kuroda, H., Wessely, O. & Robertis, E. M. Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, β-catenin, and Cerberus. PLoS Biol. 2, 623-633 (2004).
    • (2004) PLoS Biol. , vol.2 , pp. 623-633
    • Kuroda, H.1    Wessely, O.2    Robertis, E.M.3
  • 36
    • 0024845224 scopus 로고
    • Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer
    • Grunz, H. & Tacke, L. Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ. Dev. 28, 211-217 (1989).
    • (1989) Cell Differ. Dev. , vol.28 , pp. 211-217
    • Grunz, H.1    Tacke, L.2
  • 37
    • 0029059425 scopus 로고
    • Induction of epidermis and inhibition of neural fate by Bmp-4
    • Wilson, P. A. & Hemmati-Brivanlou, A. Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333 (1995).
    • (1995) Nature , vol.376 , pp. 331-333
    • Wilson, P.A.1    Hemmati-Brivanlou, A.2
  • 38
    • 18244372451 scopus 로고    scopus 로고
    • Default neural induction: Neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation
    • Kuroda, H., Fuentealba, L., Ikeda, A., Reversade, B. & De Robertis, E. M. Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation. Genes Dev. 19, 1022-1027 (2005).
    • (2005) Genes Dev. , vol.19 , pp. 1022-1027
    • Kuroda, H.1    Fuentealba, L.2    Ikeda, A.3    Reversade, B.4    De Robertis, E.M.5
  • 39
    • 0347991862 scopus 로고    scopus 로고
    • Integration of Smad and MAPK pathways: A link and a linker revisited
    • Massagué, J. Integration of Smad and MAPK pathways: a link and a linker revisited. Genes Dev. 17, 3023-3028 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 3023-3028
    • Massagué, J.1
  • 40
    • 19744364989 scopus 로고    scopus 로고
    • Neural induction: Old problem, new findings, yet more questions
    • Stern, C. D. Neural induction: old problem, new findings, yet more questions. Development 132, 2007-2021 (2005).
    • (2005) Development , vol.132 , pp. 2007-2021
    • Stern, C.D.1
  • 41
    • 24344442989 scopus 로고    scopus 로고
    • Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos
    • Reversade, B., Kuroda, H., Lee, H., Mays, A. & De Robertis, E. M. Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development 132, 3381-3392 (2005).
    • (2005) Development , vol.132 , pp. 3381-3392
    • Reversade, B.1    Kuroda, H.2    Lee, H.3    Mays, A.4    De Robertis, E.M.5
  • 42
    • 28944438059 scopus 로고    scopus 로고
    • Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field
    • Reversade, B. & De Robertis, E. M. Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. Cell 123, 1147-1160 (2005).
    • (2005) Cell , vol.123 , pp. 1147-1160
    • Reversade, B.1    De Robertis, E.M.2
  • 43
    • 0030665807 scopus 로고    scopus 로고
    • Cleavage of Chordin by the Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity
    • Piccolo, S. et al. Cleavage of Chordin by the Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell 91, 407-416 (1997).
    • (1997) Cell , vol.91 , pp. 407-416
    • Piccolo, S.1
  • 44
    • 0036895356 scopus 로고    scopus 로고
    • Xolloid-related: A novel BMP1/Tolloid-related metalloprotease is expressed during early Xenopus development
    • Dale, L., Evans, W. & Goodman, S. A. Xolloid-related: a novel BMP1/Tolloid-related metalloprotease is expressed during early Xenopus development. Mech. Dev. 119, 177-190 (2002).
    • (2002) Mech. Dev. , vol.119 , pp. 177-190
    • Dale, L.1    Evans, W.2    Goodman, S.A.3
  • 45
    • 30344486313 scopus 로고    scopus 로고
    • Embryonic dorsal-ventral signaling: Secreted frizzled-related proteins as inhibitors of tolloid proteinases
    • Lee, H. X., Ambrosio, A. L., Reversade, B. & De Robertis, E. M. Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell 124, 147-159 (2006).
    • (2006) Cell , vol.124 , pp. 147-159
    • Lee, H.X.1    Ambrosio, A.L.2    Reversade, B.3    De Robertis, E.M.4
  • 46
    • 0037324509 scopus 로고    scopus 로고
    • The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm
    • Collavin, L. & Kirschner, M. W. The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm. Development 130, 805-816 (2003).
    • (2003) Development , vol.130 , pp. 805-816
    • Collavin, L.1    Kirschner, M.W.2
  • 47
    • 0042913185 scopus 로고    scopus 로고
    • Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling
    • Yabe, T. et al. Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling. Development 130, 2705-2716 (2003).
    • (2003) Development , vol.130 , pp. 2705-2716
    • Yabe, T.1
  • 48
    • 0041343107 scopus 로고    scopus 로고
    • The ventralized ogon mutant phenotype is caused by a mutation in the zebrafish homologue of Sizzled, a secreted Frizzled-related protein
    • Martyn, U. & Schulte-Merker, S. The ventralized ogon mutant phenotype is caused by a mutation in the zebrafish homologue of Sizzled, a secreted Frizzled-related protein. Dev. Biol. 260, 58-67 (2003).
    • (2003) Dev. Biol. , vol.260 , pp. 58-67
    • Martyn, U.1    Schulte-Merker, S.2
  • 51
    • 0002011401 scopus 로고
    • The chemical basis of morphogenesis
    • Turing, A. M. The chemical basis of morphogenesis. Phil. Trans. Royal Soc. 237, 37-72 (1952).
    • (1952) Phil. Trans. Royal Soc. , vol.237 , pp. 37-72
    • Turing, A.M.1
  • 52
    • 0029775569 scopus 로고    scopus 로고
    • Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
    • Bouwmeester, T., Kim, S. H., Sasai, Y., Lu, B. & De Robertis, E. M. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382, 595-601 (1996).
    • (1996) Nature , vol.382 , pp. 595-601
    • Bouwmeester, T.1    Kim, S.H.2    Sasai, Y.3    Lu, B.4    De Robertis, E.M.5
  • 53
    • 0033593571 scopus 로고    scopus 로고
    • Axis development and early asymmetry in mammals
    • Beddington, R. S. P. & Robertson, E. J. Axis development and early asymmetry in mammals. Cell 96, 195-209 (1999).
    • (1999) Cell , vol.96 , pp. 195-209
    • Beddington, R.S.P.1    Robertson, E.J.2
  • 54
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • Glinka, A. et al. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391, 357-362 (1998).
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1
  • 55
    • 0037030681 scopus 로고    scopus 로고
    • Kremen proteins are Dickkopf receptors that regulate Wnt-β-catenin signalling
    • Mao, B. et al. Kremen proteins are Dickkopf receptors that regulate Wnt-β-catenin signalling. Nature 417, 664-667 (2002).
    • (2002) Nature , vol.417 , pp. 664-667
    • Mao, B.1
  • 56
    • 0342626578 scopus 로고    scopus 로고
    • The evolutionary conserved BMP-binding protein Twisted gastrulation promotes BMP signalling
    • Oelgeschläger, M., Larraín, J., Geissert, D. & De Robertis, E. M. The evolutionary conserved BMP-binding protein Twisted gastrulation promotes BMP signalling. Nature 405, 757-763 (2000).
    • (2000) Nature , vol.405 , pp. 757-763
    • Oelgeschläger, M.1    Larraín, J.2    Geissert, D.3    De Robertis, E.M.4
  • 57
    • 12344269338 scopus 로고    scopus 로고
    • Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning
    • Little, S. C. & Mullins, M. C. Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development 131, 5825-5835 (2004).
    • (2004) Development , vol.131 , pp. 5825-5835
    • Little, S.C.1    Mullins, M.C.2
  • 58
    • 13944261261 scopus 로고    scopus 로고
    • Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms
    • Xie, J. & Fisher, S. Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms. Development 132, 383-391 (2005).
    • (2005) Development , vol.132 , pp. 383-391
    • Xie, J.1    Fisher, S.2
  • 59
    • 0033619255 scopus 로고    scopus 로고
    • Silencing of TGF-β signalling by the pseudoreceptor BAMBI
    • Onichtchouk, D. et al. Silencing of TGF-β signalling by the pseudoreceptor BAMBI. Nature 401, 480-485 (1999).
    • (1999) Nature , vol.401 , pp. 480-485
    • Onichtchouk, D.1


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