Heptapeptide-loaded solid lipid nanoparticles for cosmetic anti-aging applications

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 108, Issue , 2016, Pages 304-309

  Suter, Franz ^a   Schmid, Daniel ^a   Wandrey, Franziska ^a   Zülli, Fred ^a  

^a Mibelle Biochemistry ^*  (Switzerland)

Author keywords

Cosmetic; Keap1; Nrf2; Peptide delivery; Skin; SLN; Solid lipid nanoparticles

Indexed keywords

COSMETIC; HEME OXYGENASE 1; HEPTAPEPTIDE; HEPTAPEPTIDE P7; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; PEROXIREDOXIN 1; PLACEBO; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG; DRUG CARRIER; HMOX1 PROTEIN, HUMAN; LIPID; NANOPARTICLE; NQO1 PROTEIN, HUMAN; PEPTIDE; PEROXIREDOXIN; PRDX1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); WATER;

ADULT; ARTICLE; BLISTER; CELL NUCLEUS; CELL STRUCTURE; CHEMICAL COMPOSITION; COST EFFECTIVENESS ANALYSIS; CUTANEOUS PARAMETERS; DENDRITIC CELL; DNA DAMAGE; DOUBLE BLIND PROCEDURE; DRUG FORMULATION; EMULSION; EPIDERMIS; EX VIVO STUDY; EXPLANT; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERBARISM; IN VITRO STUDY; LANGERHANS CELL; MICROFLUIDICS; NANOPHARMACEUTICS; NORMAL HUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PHYSICAL CHEMISTRY; RADIATION PROTECTION; SKIN CELL; SKIN PROTECTION; SUNBURN; ULTRAVIOLET IRRADIATION; ZETA POTENTIAL; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PRESSURE; PROTEIN MOTIF; RADIATION RESPONSE; SKIN; SKIN ABSORPTION; TEMPERATURE; TOPICAL DRUG ADMINISTRATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET RADIATION;

ADMINISTRATION, TOPICAL; ADULT; AMINO ACID MOTIFS; CALORIMETRY, DIFFERENTIAL SCANNING; COSMETICS; DNA DAMAGE; DOUBLE-BLIND METHOD; DRUG CARRIERS; EPIDERMIS; HEME OXYGENASE-1; HUMANS; LIPIDS; MICROFLUIDICS; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); NANOPARTICLES; PARTICLE SIZE; PEPTIDES; PEROXIREDOXINS; PRESSURE; SKIN; SKIN ABSORPTION; SKIN AGING; TEMPERATURE; ULTRAVIOLET RAYS; WATER;

EID: 84994246023     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2016.06.014     Document Type: Article

References (8)

1. [1] Nguyen, T., Yang, C.S., Pickett, C.B., The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress. Free Radic. Biol. Med. 37 (2004), 433–441.
2. [2] Tong, K.I., et al. Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response. Mol. Cell. Biol. 27 (2007), 7511–7521.
3. [3] Müller, R.H., Radtke, M., Wissing, S.A., Solid lipid nanoparticles (SLN) and nanostructured lipid carriers NLC) in cosmetic and dermatological preparations. Adv. Drug Deliver Rev. 54:Suppl. 1 (2002), 131–135.
4. [4] Chandrakantsing, P., Pravin, R., Veena, B., Avinash, T., Ganesh, P., Kapil, C., Abhijeet, S., Solid lipid based nanocarriers: an overview. Acta Pharm. 62 (2012), 433–472.
5. [5] Ekambaram, P., Abdul Hasan Sathali, A., Priyanka, K., Solid lipid nanoparticles. Sci. Rev. Chem. Commun. 2 (2012), 80–102.
6. [6] Pardeike, J., Hommoss, A., Müller, R.H., Lipid nanoparticles (SLN, NLC) in cosmetic and pharmpceutical dermal products. Int. J. Pharm. 366 (2009), 170–184.
7. [7] Korting, M.S., Mehnert, W., Korting, H.C., Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv. Drug Deliv. Rev. 59 (2007), 427–443.
8. [8] Jores, K., Mehnert, W., Drechsler, M., Bunjes, H., Johann, C., Mäder, K., Investigations on the structure of solid lipid nanoparticles (SLN) and oil loaded nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy. J. Control. Release 95 (2004), 217–227.