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Volumn 23, Issue 13, 2016, Pages 1680-1690

Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability

Author keywords

Apoptosis; Colorectal cancer; Lung metastasis; Mitogen activated protein kinases; Quercetin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BETA CATENIN; CASPASE 3; CASPASE 9; FLUOROURACIL; GELATIN; GELATINASE A; GELATINASE B; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; QUERCETIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; ANTINEOPLASTIC AGENT; MATRIX METALLOPROTEINASE;

EID: 84994234925     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2016.09.011     Document Type: Article
Times cited : (97)

References (39)
  • 1
    • 77950089188 scopus 로고    scopus 로고
    • Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism
    • Ansó, E., Zuazo, A., Irigoyen, M., Urdaci, M.C., Rouzaut, A., Martínez-Irujo, J.J., Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism. Biochem. Pharmacol. 79 (2010), 1600–1609.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1600-1609
    • Ansó, E.1    Zuazo, A.2    Irigoyen, M.3    Urdaci, M.C.4    Rouzaut, A.5    Martínez-Irujo, J.J.6
  • 2
    • 84938345242 scopus 로고    scopus 로고
    • Quercetin induces cell cycle arrest and apoptosis in CD133(+) cancer stem cells of human colorectal HT29 cancer cell line and enhances anticancer effects of doxorubicin
    • Atashpour, S., Fouladdel, S., Movahhed, T.K., Barzegar, E., Ghahremani, M.H., Ostad, S.N., Azizi, E., Quercetin induces cell cycle arrest and apoptosis in CD133(+) cancer stem cells of human colorectal HT29 cancer cell line and enhances anticancer effects of doxorubicin. Iran J. Basic Med. Sci. 18 (2015), 635–643.
    • (2015) Iran J. Basic Med. Sci. , vol.18 , pp. 635-643
    • Atashpour, S.1    Fouladdel, S.2    Movahhed, T.K.3    Barzegar, E.4    Ghahremani, M.H.5    Ostad, S.N.6    Azizi, E.7
  • 4
    • 0033551699 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells
    • Boulares, A.H., Yakovlev, A.G., Ivanova, V., Stoica, B.A., Wang, G., Iyer, S., Smulson, M., Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells. J. Biol. Chem. 274 (1999), 22932–22940.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22932-22940
    • Boulares, A.H.1    Yakovlev, A.G.2    Ivanova, V.3    Stoica, B.A.4    Wang, G.5    Iyer, S.6    Smulson, M.7
  • 5
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L., Karin, M., Mammalian MAP kinase signalling cascades. Nature 410 (2001), 37–40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 6
    • 84874108284 scopus 로고    scopus 로고
    • Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer
    • Chang, W.W., Hu, F.W., Yu, C.C., Wang, H.H., Feng, H.P., Lan, C., Tsai, L.L., Chang, Y.C., Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer. Head Neck 35 (2013), 413–419.
    • (2013) Head Neck , vol.35 , pp. 413-419
    • Chang, W.W.1    Hu, F.W.2    Yu, C.C.3    Wang, H.H.4    Feng, H.P.5    Lan, C.6    Tsai, L.L.7    Chang, Y.C.8
  • 7
    • 78649392125 scopus 로고    scopus 로고
    • The challenge of metastatic colorectal cancer
    • Cidón, E.U., The challenge of metastatic colorectal cancer. Clin. Med. Insights Oncol 18 (2010), 55–60.
    • (2010) Clin. Med. Insights Oncol , vol.18 , pp. 55-60
    • Cidón, E.U.1
  • 8
    • 84901264678 scopus 로고    scopus 로고
    • Oral and intraperitoneal administration of quercetin decreased lymphocyte DNA damage and plasma lipid peroxidation induced by TSA in vivo
    • 580626
    • Chan, S.T., Lin, Y.C., Chuang, C.H., Shiau, R.J., Liao, J.W., Yeh, S.L., Oral and intraperitoneal administration of quercetin decreased lymphocyte DNA damage and plasma lipid peroxidation induced by TSA in vivo. Biomed. Res. Int., 2014, 2014, 580626.
    • (2014) Biomed. Res. Int. , vol.2014
    • Chan, S.T.1    Lin, Y.C.2    Chuang, C.H.3    Shiau, R.J.4    Liao, J.W.5    Yeh, S.L.6
  • 9
    • 33646578517 scopus 로고    scopus 로고
    • Quercetin inhibition of ROS-dependent and -independent apoptosis in rat glioma C6 cells
    • Chen, T.J., Jeng, J.Y., Lin, C.W., Wu, C.Y., Chen, Y.C., Quercetin inhibition of ROS-dependent and -independent apoptosis in rat glioma C6 cells. Toxicology 223 (2006), 113–126.
    • (2006) Toxicology , vol.223 , pp. 113-126
    • Chen, T.J.1    Jeng, J.Y.2    Lin, C.W.3    Wu, C.Y.4    Chen, Y.C.5
  • 10
    • 84880041645 scopus 로고    scopus 로고
    • Traditional Chinese Medicinal Syndromes and Treatment in Colorectal Cancer
    • Deng, S., Hu, D.B., An, H.M., Traditional Chinese Medicinal Syndromes and Treatment in Colorectal Cancer. J. Cancer Ther. 3 (2012), 888–897.
    • (2012) J. Cancer Ther. , vol.3 , pp. 888-897
    • Deng, S.1    Hu, D.B.2    An, H.M.3
  • 11
    • 0029610477 scopus 로고
    • Review of the biology of Quercetin and related bioflavonoids
    • Formica, J.V., Regelson, W., Review of the biology of Quercetin and related bioflavonoids. Food. Chem. Toxicol. 33 (1995), 1061–1080.
    • (1995) Food. Chem. Toxicol. , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 12
    • 33746886979 scopus 로고    scopus 로고
    • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
    • Fulda, S., Debatin, K.M., Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25 (2006), 4798–4811.
    • (2006) Oncogene , vol.25 , pp. 4798-4811
    • Fulda, S.1    Debatin, K.M.2
  • 13
    • 68049147524 scopus 로고    scopus 로고
    • ERK activation increases nitroprusside induced apoptosis in human melanoma cells irrespective of p53 status: role of superoxide dismutases
    • Gomez-Sarosi, L.A., Strasberg-Rieber, M., Rieber, M., ERK activation increases nitroprusside induced apoptosis in human melanoma cells irrespective of p53 status: role of superoxide dismutases. Cancer Biol. Ther. 8 (2009), 1173–1182.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 1173-1182
    • Gomez-Sarosi, L.A.1    Strasberg-Rieber, M.2    Rieber, M.3
  • 14
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: building a framework
    • Gupta, G.P., Massagué, J., Cancer metastasis: building a framework. Cell 127 (2006), 679–695.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massagué, J.2
  • 15
    • 34547974814 scopus 로고    scopus 로고
    • Dietary quercetin inhibits proliferation of lung carcinoma cells
    • Hung, H., Dietary quercetin inhibits proliferation of lung carcinoma cells. Forum Nutr 60 (2007), 146–157.
    • (2007) Forum Nutr , vol.60 , pp. 146-157
    • Hung, H.1
  • 16
    • 0037509851 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer
    • Itoh, Y., Nagase, H., Matrix metalloproteinases in cancer. Essays Biochem 38 (2002), 21–36.
    • (2002) Essays Biochem , vol.38 , pp. 21-36
    • Itoh, Y.1    Nagase, H.2
  • 18
    • 84879126781 scopus 로고    scopus 로고
    • Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010
    • Jung, K.W., Won, Y.J., Kong, H.J., Oh, C.M., Seo, H.G., Lee, J.S., Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010. Cancer Res. Treat. 45 (2013), 1–14.
    • (2013) Cancer Res. Treat. , vol.45 , pp. 1-14
    • Jung, K.W.1    Won, Y.J.2    Kong, H.J.3    Oh, C.M.4    Seo, H.G.5    Lee, J.S.6
  • 19
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F., Wyllie, A.H., Currie, A.R., Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26 (1972), 239–257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 21
    • 84899499849 scopus 로고    scopus 로고
    • Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner
    • Kim, G.T., Lee, S.H., Kim, J.I., Kim, Y.M., Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner. Int. J. Mol. Med. 33 (2014), 863–869.
    • (2014) Int. J. Mol. Med. , vol.33 , pp. 863-869
    • Kim, G.T.1    Lee, S.H.2    Kim, J.I.3    Kim, Y.M.4
  • 23
    • 84899542271 scopus 로고    scopus 로고
    • Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells
    • Kim, M.C., Lee, H.J., Lim, B., Ha, K.T., Kim, S.Y., So, I., Kim, B.J., Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. Int. J. Mol. Med. 33 (2014), 1657–1663.
    • (2014) Int. J. Mol. Med. , vol.33 , pp. 1657-1663
    • Kim, M.C.1    Lee, H.J.2    Lim, B.3    Ha, K.T.4    Kim, S.Y.5    So, I.6    Kim, B.J.7
  • 24
    • 51849133195 scopus 로고    scopus 로고
    • Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells
    • Lin, C.W., Hou, W.C., Shen, S.C., Juan, S.H., Ko, C.H., Wang, L.M., Chen, Y.C., Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells. Carcinogenesis 29 (2008), 1807–1815.
    • (2008) Carcinogenesis , vol.29 , pp. 1807-1815
    • Lin, C.W.1    Hou, W.C.2    Shen, S.C.3    Juan, S.H.4    Ko, C.H.5    Wang, L.M.6    Chen, Y.C.7
  • 25
    • 0035990901 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion: role for cell migration
    • Nabeshima, K., Inoue, T., Shimao, Y., Sameshima, T., Matrix metalloproteinases in tumor invasion: role for cell migration. Pathol. Int. 52 (2002), 255–264.
    • (2002) Pathol. Int. , vol.52 , pp. 255-264
    • Nabeshima, K.1    Inoue, T.2    Shimao, Y.3    Sameshima, T.4
  • 26
    • 85027938844 scopus 로고    scopus 로고
    • [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells
    • Ryu, M.J., Chung, H.S., [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells. In Vitro Cell Dev. Biol. Anim. 51 (2015), 92–101.
    • (2015) In Vitro Cell Dev. Biol. Anim. , vol.51 , pp. 92-101
    • Ryu, M.J.1    Chung, H.S.2
  • 28
    • 84859918660 scopus 로고    scopus 로고
    • Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes
    • Shen, S.C., Lee, W.R., Yang, L.Y., Tsai, H.H., Yang, L.L., Chen, Y.C., Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes. Exp. Dermatol. 21 (2012), 370–375.
    • (2012) Exp. Dermatol. , vol.21 , pp. 370-375
    • Shen, S.C.1    Lee, W.R.2    Yang, L.Y.3    Tsai, H.H.4    Yang, L.L.5    Chen, Y.C.6
  • 29
    • 84946104726 scopus 로고    scopus 로고
    • Recent trends in preclinical drug-drug interaction studies of flavonoids–Review of case studies, issues and perspectives
    • Srinivas, N.R., Recent trends in preclinical drug-drug interaction studies of flavonoids–Review of case studies, issues and perspectives. Phytother. Res. 29 (2015), 1679–1691.
    • (2015) Phytother. Res. , vol.29 , pp. 1679-1691
    • Srinivas, N.R.1
  • 31
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh, Y.J., Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 3 (2003), 768–780.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 32
    • 84883485892 scopus 로고    scopus 로고
    • Potential targets for colorectal cancer prevention
    • Temraz, S., Mukherji, D., Shamseddine, A., Potential targets for colorectal cancer prevention. Int. J. Mol. Sci. 14 (2013), 17279–17303.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 17279-17303
    • Temraz, S.1    Mukherji, D.2    Shamseddine, A.3
  • 33
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J.P., Sleeman, J.P., Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7 (2006), 131–142.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 34
    • 79961208848 scopus 로고    scopus 로고
    • Initial steps of metastasis: cell invasion and endothelial transmigration
    • van Zijl, F., Krupitza, G., Mikulits, W., Initial steps of metastasis: cell invasion and endothelial transmigration. Mutat. Res. 728 (2011), 23–34.
    • (2011) Mutat. Res. , vol.728 , pp. 23-34
    • van Zijl, F.1    Krupitza, G.2    Mikulits, W.3
  • 35
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada, T., Penninger, J.M., Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23 (2004), 2838–2849.
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 36
    • 84871143693 scopus 로고    scopus 로고
    • Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl
    • 2012
    • Wang, G., Zhang, J., Liu, L., Sharma, S., Dong, Q., Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl. PLoS One., 7(12), 2012, e51764 2012.
    • (2012) PLoS One. , vol.7 , Issue.12 , pp. e51764
    • Wang, G.1    Zhang, J.2    Liu, L.3    Sharma, S.4    Dong, Q.5
  • 37
    • 82455175194 scopus 로고    scopus 로고
    • Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation
    • Xavier, C.P., Lima, C.F., Rohde, M., Pereira-Wilson, C., Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. Cancer Chemother. Pharmacol. 68 (2011), 1449–1457.
    • (2011) Cancer Chemother. Pharmacol. , vol.68 , pp. 1449-1457
    • Xavier, C.P.1    Lima, C.F.2    Rohde, M.3    Pereira-Wilson, C.4
  • 38
    • 84862777378 scopus 로고    scopus 로고
    • Antitumor activities of quercetin and quercetin-5',8-disulfonate in human colon and breast cancer cell lines
    • Zhang, H., Zhang, M., Yu, L., Zhao, Y., He, N., Yang, X., Antitumor activities of quercetin and quercetin-5',8-disulfonate in human colon and breast cancer cell lines. Food Chem. Toxicol. 50 (2012), 1589–1599.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 1589-1599
    • Zhang, H.1    Zhang, M.2    Yu, L.3    Zhao, Y.4    He, N.5    Yang, X.6
  • 39
    • 84925705731 scopus 로고    scopus 로고
    • Quercetin induces human colon cancer cells apoptosis by inhibiting the nuclear factor-kappa B Pathway
    • Zhang, X.A., Zhang, S., Yin, Q., Zhang, J., Quercetin induces human colon cancer cells apoptosis by inhibiting the nuclear factor-kappa B Pathway. Pharmacogn. Mag. 11 (2015), 404–409.
    • (2015) Pharmacogn. Mag. , vol.11 , pp. 404-409
    • Zhang, X.A.1    Zhang, S.2    Yin, Q.3    Zhang, J.4


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