Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia

Oncotarget

Volumn 7, Issue 40, 2016, Pages 65968-65981

  Fiorcari, Stefania ^a   Maffei, Rossana ^a   Audrito, Valentina ^b   Martinelli, Silvia ^a   Hacken, Elisaten ^c   Zucchini, Patrizia ^a   Grisendi, Giulia ^a   Potenza, Leonardo ^a   Luppi, Mario ^a   Burger, Jan A ^c   Deaglio, Silvia ^b   Marasca, Roberto ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

CLL; Ibrutinib; Immune modulation; Microenvironment; Nurse like cells

Indexed keywords

ANGIOPOIETIN RECEPTOR; BRUTON TYROSINE KINASE; CD11B ANTIGEN; CD206 ANTIGEN; IBRUTINIB; INTERLEUKIN 10; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN; STAT1 PROTEIN; UNCLASSIFIED DRUG; AGAMMAGLOBULINAEMIA TYROSINE KINASE; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; STAT1 PROTEIN, HUMAN; STAT6 PROTEIN; STAT6 PROTEIN, HUMAN; TUMOR MARKER;

ARTICLE; CELL FUNCTION; CELL POPULATION; CELL VIABILITY; CHRONIC LYMPHATIC LEUKEMIA; CONFOCAL MICROSCOPY; DOWN REGULATION; DRUG EFFICACY; DRUG POTENCY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; IMMUNOMODULATION; MACROPHAGE; MONOCYTE; MORPHOLOGY; MTT ASSAY; PHAGOCYTOSIS; POLARIZATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BLOOD; CELL PROLIFERATION; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; PROGNOSIS; TUMOR CELL CULTURE;

APOPTOSIS; BIOMARKERS, TUMOR; CELL PROLIFERATION; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MACROPHAGES; MONOCYTES; PHOSPHORYLATION; PROGNOSIS; PROTEIN-TYROSINE KINASES; PYRAZOLES; PYRIMIDINES; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR; TUMOR CELLS, CULTURED;

EID: 84994175806     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11782     Document Type: Article

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