Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease

European Journal of Pharmacology

Volumn 583, Issue 1, 2008, Pages 84-91

  Goto, Yasuaki ^a   Niidome, Tetsuhiro ^a   Hongo, Haruyuki ^a   Akaike, Akinori ^a   Kihara, Takeshi ^a   Sugimoto, Hachiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Alzheimer's disease; Amyloid peptide; Field excitatory postsynaptic potentials; Muscarinic acetylcholine receptor

Indexed keywords

ACETYLCHOLINE; AMYLOID BETA PROTEIN; ATROPINE; CHOLINERGIC RECEPTOR; MECAMYLAMINE; MUSCARINIC RECEPTOR; PHYSOSTIGMINE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CHOLINESTERASE INHIBITORS; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUTAMIC ACID; MICE; MICE, TRANSGENIC; MUSCARINIC ANTAGONISTS; NICOTINIC ANTAGONISTS; PATCH-CLAMP TECHNIQUES; PHYSOSTIGMINE; PRESENILIN-1; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC; SYNAPTIC TRANSMISSION;

EID: 39649101061     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.01.030     Document Type: Article

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