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Volumn 1, Issue 1, 2002, Pages 4-12

Hyperhomocysteinemia and Venous Thrombosis

Author keywords

coagulation; folic acid; hyperhomocysteinemia; oxyradicals; venous thrombosis; vitamin B12

Indexed keywords


EID: 84993736248     PISSN: 15347346     EISSN: None     Source Type: Journal    
DOI: 10.1177/153473460200100102     Document Type: Article
Times cited : (2)

References (96)
  • 1
    • 0029051274 scopus 로고
    • Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits
    • Toborek M, Kopieczna-Grzebieniak E, Dródz M, et al. Increased lipid peroxidation as a mechanism of methionine-induced atherosclerosis in rabbits. Atherosclerosis 1995; 115: 217-224.
    • (1995) Atherosclerosis , vol.115 , pp. 217-224
    • Toborek, M.1    Kopieczna-Grzebieniak, E.2    Dródz, M.3
  • 2
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherosclerosis
    • Welch GW, Loscalzo J. Homocysteine and atherosclerosis. N Engl J Med 1998; 338: 1042-1050.
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.W.1    Loscalzo, J.2
  • 3
    • 0029201180 scopus 로고
    • Homocysteine—an atherogenic and a thrombogenic factor?
    • Ubbink JB. Homocysteine—an atherogenic and a thrombogenic factor? Nutr Rev 1995; 53: 323-325.
    • (1995) Nutr Rev , vol.53 , pp. 323-325
    • Ubbink, J.B.1
  • 4
    • 0021894152 scopus 로고
    • The natural history of homocysteinuria due to cystathione β-synthase deficiency
    • Mudd SH, Skovby F, Levy HL, et al. The natural history of homocysteinuria due to cystathione β-synthase deficiency. Am J Hum Genet 1985; 37: 1-31.
    • (1985) Am J Hum Genet , vol.37 , pp. 1-31
    • Mudd, S.H.1    Skovby, F.2    Levy, H.L.3
  • 5
    • 0029921114 scopus 로고    scopus 로고
    • Homocysteinemia as a risk factor for deep vein thrombosis
    • den Heijer M, Kostor T, Blom HJ, et al. Homocysteinemia as a risk factor for deep vein thrombosis. N Engl J Med 1996; 334: 759-762.
    • (1996) N Engl J Med , vol.334 , pp. 759-762
    • den Heijer, M.1    Kostor, T.2    Blom, H.J.3
  • 6
    • 0030728675 scopus 로고    scopus 로고
    • Acute methionine load-induced hyperhomocysteinaemia enhances platelet aggregation, thromboxane biosynthesis, and macrophage-derived tissue factor activity in rats
    • Durand P, Lussier-Cacan S, Blache D. Acute methionine load-induced hyperhomocysteinaemia enhances platelet aggregation, thromboxane biosynthesis, and macrophage-derived tissue factor activity in rats. FASEB J 1997; 11: 1157-1168.
    • (1997) FASEB J , vol.11 , pp. 1157-1168
    • Durand, P.1    Lussier-Cacan, S.2    Blache, D.3
  • 7
    • 0033821945 scopus 로고    scopus 로고
    • Homocysteine and venous thrombosis: outline of a vitamin intervention trial
    • Willems HP, den Heijer M, Bos GM. Homocysteine and venous thrombosis: outline of a vitamin intervention trial. Semin Thromb Hemost 2000; 26: 297-304.
    • (2000) Semin Thromb Hemost , vol.26 , pp. 297-304
    • Willems, H.P.1    den Heijer, M.2    Bos, G.M.3
  • 8
    • 0034630125 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia and increased risk of venous thromboembolism: more evidence from case-control study
    • Langman LJ, Ray JG, Evrovski J, et al. Hyperhomocyst(e)inemia and increased risk of venous thromboembolism: more evidence from case-control study. Arch Intern Med 2000; 160: 961-964.
    • (2000) Arch Intern Med , vol.160 , pp. 961-964
    • Langman, L.J.1    Ray, J.G.2    Evrovski, J.3
  • 9
    • 0030971062 scopus 로고    scopus 로고
    • Homocysteine and thrombotic disease
    • D’Angelo A, Selhub J. Homocysteine and thrombotic disease. Blood 1997; 90: 1-11.
    • (1997) Blood , vol.90 , pp. 1-11
    • D’Angelo, A.1    Selhub, J.2
  • 10
    • 0024342063 scopus 로고
    • Review article: plasma homocysteine, a risk factor for vascular disease, plasma levels in health, disease and drug therapy
    • Ueland PM, Refsum H. Review article: plasma homocysteine, a risk factor for vascular disease, plasma levels in health, disease and drug therapy. J Lab Clin Med 1989; 114: 473-501.
    • (1989) J Lab Clin Med , vol.114 , pp. 473-501
    • Ueland, P.M.1    Refsum, H.2
  • 11
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • Boushey CJ, Beresford SAA, Omenn GS, et al. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. J Am Med Assoc 1995; 274: 1049-1057.
    • (1995) J Am Med Assoc , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3
  • 13
    • 0028314865 scopus 로고
    • Mutation in blood coagulation factor V associated with resistance to activated protein C
    • Bertina RM, Koeleman BP, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67.
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koeleman, B.P.2    Koster, T.3
  • 14
    • 0029850530 scopus 로고    scopus 로고
    • A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Port SR, Rosendaal FR, Reitsma PH, et al. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-3703.
    • (1996) Blood , vol.88 , pp. 3698-3703
    • Port, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3
  • 15
    • 0001627642 scopus 로고
    • Inherited antithrombin III deficiency causing thrombophilia
    • Egeberg O. Inherited antithrombin III deficiency causing thrombophilia. Thromb Diath Haemorrh 1965; 13: 516-530.
    • (1965) Thromb Diath Haemorrh , vol.13 , pp. 516-530
    • Egeberg, O.1
  • 16
    • 0019789514 scopus 로고
    • Deficiency of protein-c in congenital thrombotic disease
    • Griffin JH, Evatt BL, Zimmerman TS, et al. Deficiency of protein-c in congenital thrombotic disease. J Clin Invest 1981; 68: 1370-1373.
    • (1981) J Clin Invest , vol.68 , pp. 1370-1373
    • Griffin, J.H.1    Evatt, B.L.2    Zimmerman, T.S.3
  • 17
    • 0027465837 scopus 로고
    • Increased risk of venous thrombosis in carriers of hereditary protein-c deficiency defect
    • Allaart CF, Poort SR, Rosendaal FR, et al. Increased risk of venous thrombosis in carriers of hereditary protein-c deficiency defect. Lancet 1993; 341: 134-138.
    • (1993) Lancet , vol.341 , pp. 134-138
    • Allaart, C.F.1    Poort, S.R.2    Rosendaal, F.R.3
  • 18
    • 0029016883 scopus 로고
    • Resistance to activated protein C as the additional genetic risk factor in hereditary deficiency of protein S
    • Zöller B, Berntsdottes A, Garcia de Fructos P, et al. Resistance to activated protein C as the additional genetic risk factor in hereditary deficiency of protein S. Blood 1995; 85: 3518-3523.
    • (1995) Blood , vol.85 , pp. 3518-3523
    • Zöller, B.1    Berntsdottes, A.2    Garcia de Fructos, P.3
  • 19
    • 0028342850 scopus 로고
    • Factor VII and fibrinogen levels as risk factors for venous thrombosis: a case-control study of plasma levels and DNA polymorphisms: the Leiden Thrombophilia Study (LETS)
    • Koster T, Rosendaal FR, Reitsma PH, et al. Factor VII and fibrinogen levels as risk factors for venous thrombosis: a case-control study of plasma levels and DNA polymorphisms: the Leiden Thrombophilia Study (LETS). Thromb Haemost 1994; 71: 719-722.
    • (1994) Thromb Haemost , vol.71 , pp. 719-722
    • Koster, T.1    Rosendaal, F.R.2    Reitsma, P.H.3
  • 20
    • 0022392642 scopus 로고
    • The anticardiolipin syndrome
    • Hughes GR. The anticardiolipin syndrome. Clin Exp Rheumatol 1985; 3: 285-286.
    • (1985) Clin Exp Rheumatol , vol.3 , pp. 285-286
    • Hughes, G.R.1
  • 21
    • 0028814316 scopus 로고
    • Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep vein thrombosis
    • Koster T, Blann AD, Briët E, et al. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep vein thrombosis. Lancet 1995; 345: 152-155.
    • (1995) Lancet , vol.345 , pp. 152-155
    • Koster, T.1    Blann, A.D.2    Briët, E.3
  • 22
    • 0033983988 scopus 로고    scopus 로고
    • High plasma concentration of factor VIIIc is a major risk factor for venous thromboembolism
    • Kraaijenhagen RA, Anker PS, Koopman MM, et al. High plasma concentration of factor VIIIc is a major risk factor for venous thromboembolism. Thromb Haemost 2000; 83: 5-9.
    • (2000) Thromb Haemost , vol.83 , pp. 5-9
    • Kraaijenhagen, R.A.1    Anker, P.S.2    Koopman, M.M.3
  • 23
    • 0027293835 scopus 로고
    • Total homocysteine in plasma or serum. Methods and clinical application
    • Ueland PM, Refsum H, Stabler SP, et al. Total homocysteine in plasma or serum. Methods and clinical application. Clin Chem 1993; 39: 1764-1779.
    • (1993) Clin Chem , vol.39 , pp. 1764-1779
    • Ueland, P.M.1    Refsum, H.2    Stabler, S.P.3
  • 24
    • 0023243925 scopus 로고
    • Homocysteinemia due to folate deficiency
    • Kang S-S, Wong PWK, Norusis M. Homocysteinemia due to folate deficiency. Metabolism 1987; 36: 458-462.
    • (1987) Metabolism , vol.36 , pp. 458-462
    • Kang, S.-S.1    Wong, P.W.K.2    Norusis, M.3
  • 25
    • 0022471265 scopus 로고
    • Protein-bound homocyst(e)ine: a possible risk factor for coronary artery disease
    • Kang S-S, Wong PWK, Cook HY, et al. Protein-bound homocyst(e)ine: a possible risk factor for coronary artery disease. J Clin Invest 1986; 77: 1482-1486.
    • (1986) J Clin Invest , vol.77 , pp. 1482-1486
    • Wong, P.W.K.1    Cook, H.Y.2
  • 26
    • 0026633925 scopus 로고
    • Hyperhomocysteinemia as a risk factor for occlusive vascular disease
    • Kang S-S, Wong PWK, Malinow MR. Hyperhomocysteinemia as a risk factor for occlusive vascular disease. Annu Rev Nutr 1992; 12: 279-298.
    • (1992) Annu Rev Nutr , vol.12 , pp. 279-298
    • Wong, P.W.K.1    Malinow, M.R.2
  • 27
    • 0032953385 scopus 로고    scopus 로고
    • Homocysteine, a risk factor for cardiovascular disease
    • Prasad K. Homocysteine, a risk factor for cardiovascular disease. Int J Angiol 1999; 8: 76-86.
    • (1999) Int J Angiol , vol.8 , pp. 76-86
    • Prasad, K.1
  • 28
    • 0000167774 scopus 로고
    • Disorders of transsulfuration
    • In: Scriver CR, Beaudet AL, Sly WS, et al, editors. New York: McGraw-Hill p.
    • Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, et al, editors. The metabolic and molecular basis of inherited disease. New York: McGraw-Hill; 1995. p. 1279-1327.
    • (1995) The metabolic and molecular basis of inherited disease , pp. 1279-1327
    • Mudd, S.H.1    Levy, H.L.2    Skovby, F.3
  • 30
    • 0023696435 scopus 로고
    • Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase
    • Kang S-S, Zhou J, Wong PWK, et al. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988; 43: 414-421.
    • (1988) Am J Hum Genet , vol.43 , pp. 414-421
    • Zhou, J.1    Wong, P.W.K.2
  • 31
    • 0026664205 scopus 로고
    • Effect of vitamin B6 deficiency on fasting plasma homocysteine concentrations
    • Miller JW, Ribayamercado JD, Russell RM, et al. Effect of vitamin B6 deficiency on fasting plasma homocysteine concentrations. Am J Clin Nutr 1992; 55: 1154-1160.
    • (1992) Am J Clin Nutr , vol.55 , pp. 1154-1160
    • Miller, J.W.1    Ribayamercado, J.D.2    Russell, R.M.3
  • 32
    • 0027423427 scopus 로고
    • Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency
    • Allen RH, Stabler SP, Savage DG, et al. Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency. FASEB J 1994; 7: 1344-1353.
    • (1994) FASEB J , vol.7 , pp. 1344-1353
    • Allen, R.H.1    Stabler, S.P.2    Savage, D.G.3
  • 33
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques PF, Wilson PWF, et al. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993; 270: 2693-2698.
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.F.3
  • 34
    • 0018814788 scopus 로고
    • Vessel proteoglycans and thrombogenesis
    • In: Spact TH, editor. New York: Grume & Stratton p.
    • Wight TN. Vessel proteoglycans and thrombogenesis. In: Spact TH, editor. Progress in hemostasis and thrombosis. New York: Grume & Stratton; 1980. p. 1-39.
    • (1980) Progress in hemostasis and thrombosis , pp. 1-39
    • Wight, T.N.1
  • 35
    • 0000650903 scopus 로고
    • Identification of endothelial cell cofactor for thrombin-catalyzed activation of protein C
    • Esmon CT, Owen WG. Identification of endothelial cell cofactor for thrombin-catalyzed activation of protein C. Proc Natl Acad Sci U S A 1981; 78: 2249-2252.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 2249-2252
    • Esmon, C.T.1    Owen, W.G.2
  • 36
    • 0017527971 scopus 로고
    • Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells
    • Weksler BB, Marcus AJ, Jaffe EA. Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells. Proc Natl Acad Sci U S A 1977; 74: 3922-3926.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 3922-3926
    • Weksler, B.B.1    Marcus, A.J.2    Jaffe, E.A.3
  • 37
    • 0343759135 scopus 로고
    • Synthesis of a fibrinolytic activator and inhibitor by endothelial cells
    • Loskuttoff DJ, Edgington TS. Synthesis of a fibrinolytic activator and inhibitor by endothelial cells. Proc Natl Acad Sci U S A 1977; 74: 3903-3907.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 3903-3907
    • Loskuttoff, D.J.1    Edgington, T.S.2
  • 38
    • 0027247803 scopus 로고
    • Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism
    • Di Minno G, Davi G, Margaglione M, et al. Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism. J Clin Invest 1993; 92: 1400-1408.
    • (1993) J Clin Invest , vol.92 , pp. 1400-1408
    • Di Minno, G.1    Davi, G.2    Margaglione, M.3
  • 39
    • 0020055946 scopus 로고
    • Effect of homocysteine and homocysteine on platelet and vascular arachidonic acid metabolism
    • Graeber JE, Slott JH, Ulane RE, et al. Effect of homocysteine and homocysteine on platelet and vascular arachidonic acid metabolism. Pediatr Res 1982; 16: 490-493.
    • (1982) Pediatr Res , vol.16 , pp. 490-493
    • Graeber, J.E.1    Slott, J.H.2    Ulane, R.E.3
  • 40
    • 0000363006 scopus 로고
    • Disorders of transulfuration
    • In: Stanbury JB, Wyngaarden JB, Fredrickson DS, et al, editors. 5th ed. New York: McGraw-Hill p.
    • Mudd SH, Levy HL. Disorders of transulfuration. In: Stanbury JB, Wyngaarden JB, Fredrickson DS, et al, editors. The metabolic basis of inherited disease. 5th ed. New York: McGraw-Hill; 1983. p. 522-559.
    • (1983) The metabolic basis of inherited disease , pp. 522-559
    • Mudd, S.H.1    Levy, H.L.2
  • 41
    • 50549209636 scopus 로고
    • Homocystinuria, thrombosis, and the blood-platelets
    • McDonald L, Bray C, Field C, et al. Homocystinuria, thrombosis, and the blood-platelets. Lancet 1964; 1: 745-746.
    • (1964) Lancet , vol.1 , pp. 745-746
    • McDonald, L.1    Bray, C.2    Field, C.3
  • 42
    • 0022472013 scopus 로고
    • Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator
    • Rodgers GM, Kane WH. Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest 1986; 77: 1909-1916.
    • (1986) J Clin Invest , vol.77 , pp. 1909-1916
    • Rodgers, G.M.1    Kane, W.H.2
  • 43
    • 0019862464 scopus 로고
    • Purification and characterization of human coagulation factor V
    • Kane WH, Majerus PW. Purification and characterization of human coagulation factor V. J Biol Chem 1981; 256: 1002-1007.
    • (1981) J Biol Chem , vol.256 , pp. 1002-1007
    • Kane, W.H.1    Majerus, P.W.2
  • 44
    • 0014434483 scopus 로고
    • Activation of Hageman factor by L-homocysteine
    • Ratnoff OD. Activation of Hageman factor by L-homocysteine. Science 1968; 162: 1007-1009.
    • (1968) Science , vol.162 , pp. 1007-1009
    • Ratnoff, O.D.1
  • 45
    • 0027472128 scopus 로고
    • Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum
    • Lenz SR, Sadler JE. Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum. Blood 1993; 81: 683-689.
    • (1993) Blood , vol.81 , pp. 683-689
    • Lenz, S.R.1    Sadler, J.E.2
  • 47
    • 0023664723 scopus 로고
    • The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells
    • Heinecke JW, Rosen H, Suzuki LA, et al. The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. J Biol Chem 1987; 262: 10098-10103.
    • (1987) J Biol Chem , vol.262 , pp. 10098-10103
    • Heinecke, J.W.1    Rosen, H.2    Suzuki, L.A.3
  • 48
    • 0027278957 scopus 로고
    • Homocysteine metabolism and the oxidative modification of proteins and lipids
    • Olszewski AJ, McCully KS. Homocysteine metabolism and the oxidative modification of proteins and lipids. Free Radic Biol Med 1993; 14: 683-693.
    • (1993) Free Radic Biol Med , vol.14 , pp. 683-693
    • Olszewski, A.J.1    McCully, K.S.2
  • 49
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
    • Stamler JS, Osborne JA, Jaraki O, et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest 1993; 91: 308-318.
    • (1993) J Clin Invest , vol.91 , pp. 308-318
    • Stamler, J.S.1    Osborne, J.A.2    Jaraki, O.3
  • 50
    • 0000849736 scopus 로고    scopus 로고
    • Homocyst(e)ine decreases cell redox potential in vascular smooth muscle cells
    • Abstract.
    • Welch GN, Upchurch GR, Keaney JF, et al. Homocyst(e)ine decreases cell redox potential in vascular smooth muscle cells. J Am Coll Cardiol 1996; 27(Suppl A):163A. Abstract.
    • (1996) J Am Coll Cardiol , vol.27 , Issue.Suppl A , pp. 163A
    • Welch, G.N.1    Upchurch, G.R.2    Keaney, J.F.3
  • 51
    • 0015954510 scopus 로고
    • Generation of superoxide free radical during auto-oxidation of thiols
    • Misra HP. Generation of superoxide free radical during auto-oxidation of thiols. J Biol Chem 1974; 249: 2151-2155.
    • (1974) J Biol Chem , vol.249 , pp. 2151-2155
    • Misra, H.P.1
  • 52
    • 0020477158 scopus 로고
    • Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds
    • Rowley DA, Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds. FEBS Lett 1982; 138: 33-36.
    • (1982) FEBS Lett , vol.138 , pp. 33-36
    • Rowley, D.A.1    Halliwell, B.2
  • 53
    • 0033961048 scopus 로고    scopus 로고
    • Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta
    • Lang D, Kredan MB, Moat SJ, et al. Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta. Arterioscler Thromb Vasc Biol 2000; 20: 422-427.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 422-427
    • Lang, D.1    Kredan, M.B.2    Moat, S.J.3
  • 54
    • 0031434241 scopus 로고    scopus 로고
    • Role of oxygen radicals in tissue factor induction by endotoxin in blood monocytes
    • Polack B, Pernod G, Barro C, et al. Role of oxygen radicals in tissue factor induction by endotoxin in blood monocytes. Haemostasis 1997; 27: 193-200.
    • (1997) Haemostasis , vol.27 , pp. 193-200
    • Polack, B.1    Pernod, G.2    Barro, C.3
  • 55
    • 0026500781 scopus 로고
    • Modulation of the fibrinolytic response of cultured human vascular endothelium by extracellularly generated oxygen radicals
    • Shatos MA, Doherty JM, Orfeo T, et al. Modulation of the fibrinolytic response of cultured human vascular endothelium by extracellularly generated oxygen radicals. J Biol Chem 1992; 267: 597-601.
    • (1992) J Biol Chem , vol.267 , pp. 597-601
    • Shatos, M.A.1    Doherty, J.M.2    Orfeo, T.3
  • 56
    • 0029039467 scopus 로고
    • Experimental thrombosis model induced by free radicals: application to aspirin and other different substances
    • Jourdan A, Aguejouf O, Imbault P, et al. Experimental thrombosis model induced by free radicals: application to aspirin and other different substances. Thromb Res 1995; 79: 109-123.
    • (1995) Thromb Res , vol.79 , pp. 109-123
    • Jourdan, A.1    Aguejouf, O.2    Imbault, P.3
  • 57
    • 0026773724 scopus 로고
    • An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells
    • Hayashi T, Honda TG, Suzuki K. An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells. Blood 1992; 79: 2930-2936.
    • (1992) Blood , vol.79 , pp. 2930-2936
    • Hayashi, T.1    Honda, T.G.2    Suzuki, K.3
  • 58
    • 0025190042 scopus 로고
    • Homocysteine, an atherogenic stimulus, reduces protein c activation by arterial and venous endothelial cells
    • Rodgers GM, Conn MT. Homocysteine, an atherogenic stimulus, reduces protein c activation by arterial and venous endothelial cells. Blood 1990; 75: 895-901.
    • (1990) Blood , vol.75 , pp. 895-901
    • Rodgers, G.M.1    Conn, M.T.2
  • 59
    • 0026345948 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein-c activation by thrombogenic agent homocysteine
    • Lenz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein-c activation by thrombogenic agent homocysteine. J Clin Invest 1991; 88: 1906-1914.
    • (1991) J Clin Invest , vol.88 , pp. 1906-1914
    • Lenz, S.R.1    Sadler, J.E.2
  • 60
    • 0027319970 scopus 로고
    • Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
    • Nishinaga M, Ozawa T, Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest 1993; 92: 1381-1386.
    • (1993) J Clin Invest , vol.92 , pp. 1381-1386
    • Nishinaga, M.1    Ozawa, T.2    Shimada, K.3
  • 61
    • 0027288252 scopus 로고
    • Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor
    • Hajjar KA. Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Invest 1993; 91: 2873-2879.
    • (1993) J Clin Invest , vol.91 , pp. 2873-2879
    • Hajjar, K.A.1
  • 62
    • 0017197285 scopus 로고
    • Homocysteine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis
    • Harker LA, Ross R, Slichter SJ, et al. Homocysteine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis. J Clin Invest 1976; 58: 731-741.
    • (1976) J Clin Invest , vol.58 , pp. 731-741
    • Harker, L.A.1    Ross, R.2    Slichter, S.J.3
  • 63
    • 0018858624 scopus 로고
    • Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury
    • Wall RT, Harlan LM, Harker LA, et al. Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thromb Res 1980; 18: 113-121.
    • (1980) Thromb Res , vol.18 , pp. 113-121
    • Wall, R.T.1    Harlan, L.M.2    Harker, L.A.3
  • 64
    • 0342624737 scopus 로고    scopus 로고
    • Homocysteine mediated endothelial cell toxicity and its amelioration
    • Blundell G, Jones BG, Rose FA, et al. Homocysteine mediated endothelial cell toxicity and its amelioration. Atherosclerosis 1996; 122: 163-172.
    • (1996) Atherosclerosis , vol.122 , pp. 163-172
    • Blundell, G.1    Jones, B.G.2    Rose, F.A.3
  • 65
    • 0025891903 scopus 로고
    • A population based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worchester DVT Study
    • Anderson FA, Wheeler HB, Goldberg RJ, et al. A population based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worchester DVT Study. Arch Intern Med 1991; 151: 933-938.
    • (1991) Arch Intern Med , vol.151 , pp. 933-938
    • Anderson, F.A.1    Wheeler, H.B.2    Goldberg, R.J.3
  • 66
    • 0026764834 scopus 로고
    • A prospective study of the incidence of deep vein thrombosis within a defined urban population
    • Nordstrom M, Lindblad B, Bergquist D, et al. A prospective study of the incidence of deep vein thrombosis within a defined urban population. J Intern Med 1992; 232: 155-160.
    • (1992) J Intern Med , vol.232 , pp. 155-160
    • Nordstrom, M.1    Lindblad, B.2    Bergquist, D.3
  • 67
    • 0014233317 scopus 로고
    • Hypercoagulability associated with chronic ulcerative colitis: changes in blood coagulation factors
    • Lee JCL, Spittell JA, Sauer WG, et al. Hypercoagulability associated with chronic ulcerative colitis: changes in blood coagulation factors. Gastroenterol 1968; 54: 76-85.
    • (1968) Gastroenterol , vol.54 , pp. 76-85
    • Lee, J.C.L.1    Spittell, J.A.2    Sauer, W.G.3
  • 68
    • 0029033740 scopus 로고
    • Protein-c deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study)
    • Koster T, Rosendaal FR, Briet E, et al. Protein-c deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study). Blood 1995; 85: 2756-2761.
    • (1995) Blood , vol.85 , pp. 2756-2761
    • Koster, T.1    Rosendaal, F.R.2    Briet, E.3
  • 69
    • 0028931717 scopus 로고
    • High risk of thrombosis in patients homozygous for factor V Leiden (activated protein-c resistance)
    • Rosendaal FR, Koster T, Vandenbrouke JP, et al. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein-c resistance). Blood 1995; 85: 1504-1508.
    • (1995) Blood , vol.85 , pp. 1504-1508
    • Rosendaal, F.R.1    Koster, T.2    Vandenbrouke, J.P.3
  • 70
    • 76549221821 scopus 로고
    • Homocystinuria: studies of 20 families with 38 affected members
    • Schimke RN, McKusick VA, Huang T, et al. Homocystinuria: studies of 20 families with 38 affected members. JAMA 1965; 193: 711-719.
    • (1965) JAMA , vol.193 , pp. 711-719
    • Schimke, R.N.1    McKusick, V.A.2    Huang, T.3
  • 71
    • 0000343368 scopus 로고
    • Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland
    • Carson NAJ, Neill DW. Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland. Arch Dis Child 1962; 37: 505-513.
    • (1962) Arch Dis Child , vol.37 , pp. 505-513
    • Carson, N.A.J.1    Neill, D.W.2
  • 73
    • 0027156287 scopus 로고
    • Elevated total plasma homocysteine, a risk factor for thrombosis. Relation to coagulation and fibrinolytic parameters
    • Bienvenu T, Ankri A, Chadefaux B, et al. Elevated total plasma homocysteine, a risk factor for thrombosis. Relation to coagulation and fibrinolytic parameters. Thromb Res 1993; 70: 123-129.
    • (1993) Thromb Res , vol.70 , pp. 123-129
    • Bienvenu, T.1    Ankri, A.2    Chadefaux, B.3
  • 74
    • 0025736121 scopus 로고
    • Plasma homocysteine in venous thromboembolism
    • Brattstrom L, Tengborn L, Lagerstedt C, et al. Plasma homocysteine in venous thromboembolism. Haemostasis 1991; 21: 51-57.
    • (1991) Haemostasis , vol.21 , pp. 51-57
    • Brattstrom, L.1    Tengborn, L.2    Lagerstedt, C.3
  • 75
    • 0028335097 scopus 로고
    • High prevalence of hyperhomocyst(e)inemia in patients with juvenile venous thrombosis
    • Falcon CR, Cattaneo M, Panzeri D, et al. High prevalence of hyperhomocyst(e)inemia in patients with juvenile venous thrombosis. Arterioscler Thromb 1994; 14: 1080-1083.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1080-1083
    • Falcon, C.R.1    Cattaneo, M.2    Panzeri, D.3
  • 76
    • 0029116984 scopus 로고
    • Plasma homocysteine levels in patients with deep venous thrombosis
    • Amundsen T, Ueland PM, Waage A. Plasma homocysteine levels in patients with deep venous thrombosis. Arterioscler Thromb Vasc Biol 1995; 15: 1321-1323.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1321-1323
    • Amundsen, T.1    Ueland, P.M.2    Waage, A.3
  • 77
    • 0028853921 scopus 로고
    • Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease
    • Fermo I, Vigano’ D’Angelo S, Paroni R, et al. Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease. Ann Intern Med 1995; 123: 747-753.
    • (1995) Ann Intern Med , vol.123 , pp. 747-753
    • Fermo, I.1    Vigano’ D’Angelo, S.2    Paroni, R.3
  • 78
    • 0028949953 scopus 로고
    • Is hyperhomocysteinemia a risk factor for recurrent venous thrombosis?
    • den Heijer M, Blom HJ, Gerrits WB, et al. Is hyperhomocysteinemia a risk factor for recurrent venous thrombosis? Lancet 1995; 345: 882-885.
    • (1995) Lancet , vol.345 , pp. 882-885
    • den Heijer, M.1    Blom, H.J.2    Gerrits, W.B.3
  • 79
    • 0029790344 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as a risk factor for deep vein thrombosis
    • Cattaneo M, Martinelli I, Mannucci PM. Hyperhomocysteinemia as a risk factor for deep vein thrombosis. N Engl J Med 1996; 335: 974-975.
    • (1996) N Engl J Med , vol.335 , pp. 974-975
    • Cattaneo, M.1    Martinelli, I.2    Mannucci, P.M.3
  • 80
    • 0030299976 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and deep vein thrombosis
    • Simioni P, Prandoni P, Burlina A, et al. Hyperhomocysteinemia and deep vein thrombosis. Thromb Haemost 1996; 76: 883-886.
    • (1996) Thromb Haemost , vol.76 , pp. 883-886
    • Simioni, P.1    Prandoni, P.2    Burlina, A.3
  • 81
    • 0030953866 scopus 로고    scopus 로고
    • Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism
    • Ridker PM, Hennekens CH, Selhub J, et al. Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation 1997; 95: 1777-1782.
    • (1997) Circulation , vol.95 , pp. 1777-1782
    • Ridker, P.M.1    Hennekens, C.H.2    Selhub, J.3
  • 82
    • 0031754849 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is a risk factor of recurrent venous thromboembolism
    • Eichinger S, Stumpflen A, Hirschl M, et al. Hyperhomocysteinemia is a risk factor of recurrent venous thromboembolism. Thromb Haemost 1998; 80: 566-569.
    • (1998) Thromb Haemost , vol.80 , pp. 566-569
    • Eichinger, S.1    Stumpflen, A.2    Hirschl, M.3
  • 83
    • 0033821945 scopus 로고    scopus 로고
    • Homocysteine and venous thrombosis. Outline of a vitamin intervention trial
    • Willems HPG, den Heijer M, Bos GMG. Homocysteine and venous thrombosis. Outline of a vitamin intervention trial. Semin Thromb Hemost 2000; 26: 297-304.
    • (2000) Semin Thromb Hemost , vol.26 , pp. 297-304
    • Willems, H.P.G.1    den Heijer, M.2    Bos, G.M.G.3
  • 84
    • 0031733260 scopus 로고
    • Hyperhomocysteinemia and venous thrombosis: a meta-analysis
    • den Heijer M, Rosendaal FR, Blom HJ, et al. Hyperhomocysteinemia and venous thrombosis: a meta-analysis. Thromb Haemost 1988; 80: 874-877.
    • (1988) Thromb Haemost , vol.80 , pp. 874-877
    • den Heijer, M.1    Rosendaal, F.R.2    Blom, H.J.3
  • 85
    • 0032569645 scopus 로고    scopus 로고
    • Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
    • Ray JG. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 1998; 158: 2101-2206.
    • (1998) Arch Intern Med , vol.158 , pp. 2101-2206
    • Ray, J.G.1
  • 86
    • 0030603334 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus
    • Petri M, Roubenoff R, Dallol GE, Nadeau MR, Selhub J, Rosenburg IH. Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus. Lancet 1996; 348: 1120-1124.
    • (1996) Lancet , vol.348 , pp. 1120-1124
    • Petri, M.1    Roubenoff, R.2    Dallol, G.E.3    Nadeau, M.R.4    Selhub, J.5    Rosenburg, I.H.6
  • 87
    • 0029655771 scopus 로고    scopus 로고
    • Long term folic acid (but not pyridoxine) supplementation lowers elevated plasma homocysteine level in chronic renal failures
    • Chauveau P, Chadefaux B, Conde M, et al. Long term folic acid (but not pyridoxine) supplementation lowers elevated plasma homocysteine level in chronic renal failures. Miner Electrolyte Metab 1996; 22: 106-109.
    • (1996) Miner Electrolyte Metab , vol.22 , pp. 106-109
    • Chauveau, P.1    Chadefaux, B.2    Conde, M.3
  • 88
    • 84993778903 scopus 로고    scopus 로고
    • High plasma homocysteine in patients with coronary artery disease can be reduced by folic acid supplementation
    • Abou-Gazala T, Lobo A, Alsous F, et al. High plasma homocysteine in patients with coronary artery disease can be reduced by folic acid supplementation. J Am Coll Cardiol 1997; 27(Suppl 2A):488A.
    • (1997) J Am Coll Cardiol , vol.27 , pp. 488A
    • Abou-Gazala, T.1    Lobo, A.2    Alsous, F.3
  • 89
    • 0030975769 scopus 로고    scopus 로고
    • The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolase reductase genotypes
    • Malinow MR, Nieto FJ, Kruger WD, et al. The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolase reductase genotypes. Arterioscler Thromb Vasc Biol 1997; 17: 1157-1162.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1157-1162
    • Malinow, M.R.1    Nieto, F.J.2    Kruger, W.D.3
  • 90
    • 0028950274 scopus 로고
    • Plasma homocysteine in acute myocardial infarction: homocysteine-lowering effect of folic acid
    • Landgren F, Israelsson B, Lindgren A, et al. Plasma homocysteine in acute myocardial infarction: homocysteine-lowering effect of folic acid. J Intern Med 1995; 237: 381-388.
    • (1995) J Intern Med , vol.237 , pp. 381-388
    • Landgren, F.1    Israelsson, B.2    Lindgren, A.3
  • 91
    • 0028028118 scopus 로고
    • Vitamin requirements for the treatment of hyperhomocysteinemia in humans
    • Ubbink JB, Vermaak WJ, Vander Merwe A, et al. Vitamin requirements for the treatment of hyperhomocysteinemia in humans. J Nutr 1994; 124: 1927-1933.
    • (1994) J Nutr , vol.124 , pp. 1927-1933
    • Ubbink, J.B.1    Vermaak, W.J.2    Vander, M.A.3
  • 93
    • 2242477014 scopus 로고    scopus 로고
    • Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomized trials
    • Homocysteine lowering trialists’ collaboration. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomized trials. Br Med J 1998; 316: 894-898.
    • (1998) Br Med J , vol.316 , pp. 894-898
  • 94
    • 0032499126 scopus 로고    scopus 로고
    • Reduction of plasma homocysteine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease
    • Malinow MR, Duell PB, Hess DL, et al. Reduction of plasma homocysteine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease. N Engl J Med 1998; 338: 1009-1015.
    • (1998) N Engl J Med , vol.338 , pp. 1009-1015
    • Malinow, M.R.1    Duell, P.B.2    Hess, D.L.3
  • 95
    • 0033551352 scopus 로고    scopus 로고
    • The effect of folic acid fortification on plasma folate and total homocysteine concentrations
    • Jacques PF, Selhub J, Bostom AG, et al. The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med 1999; 340: 1449-1454.
    • (1999) N Engl J Med , vol.340 , pp. 1449-1454
    • Jacques, P.F.1    Selhub, J.2    Bostom, A.G.3
  • 96
    • 0033673425 scopus 로고    scopus 로고
    • The venous stasis syndrome after deep vein thrombosis or pulmonary embolism: a population based study
    • Mohr DN, Silverstein MD, Heit JD, et al. The venous stasis syndrome after deep vein thrombosis or pulmonary embolism: a population based study. Mayo Clin Proc 2000; 75: 1249-1256.
    • (2000) Mayo Clin Proc , vol.75 , pp. 1249-1256
    • Mohr, D.N.1    Silverstein, M.D.2    Heit, J.D.3


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