RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

Oncotarget

Volumn 7, Issue 39, 2016, Pages 63779-63792

  Dächert, Jasmin ^a   Schoeneberger, Hannah ^a   Rohde, Katharina ^a   Fulda, Simone ^a,b  

^a GOETHE UNIVERSITY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Cell death; Ferroptosis; Redox; ROS; Smac mimetic

Indexed keywords

ALPHA TOCOPHEROL; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 7; CHONDROITIN SULFATE IRON; DEFEROXAMINE; ENZYME INHIBITOR; ERASTIN; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR INTERACTING PROTEIN 3; RSL3; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CARBOLINE DERIVATIVE; DIABLO PROTEIN, HUMAN; IRON; MITOCHONDRIAL PROTEIN; PEPTIDE CHLOROMETHYL KETONE; PIPERAZINE DERIVATIVE; RSL3 COMPOUND; SIGNAL PEPTIDE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIPID PEROXIDATION; OXIDATION REDUCTION STATE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN TARGETING; REGULATORY MECHANISM; CELL DEATH; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE SILENCING; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CARBOLINES; CELL DEATH; DEFEROXAMINE; GENE EXPRESSION REGULATION, LEUKEMIC; GENE SILENCING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRON; LIPID PEROXIDATION; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATION-REDUCTION; PIPERAZINES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84993180291     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11687     Document Type: Article

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