-
1
-
-
84896697001
-
Nontuberculous mycobacterial (NTM) lung disease: the top ten essentials
-
Aksamit, T. R., Philley, J. V., and Griffith, D. E. (2014). Nontuberculous mycobacterial (NTM) lung disease: the top ten essentials. Respir. Med. 108, 417-425. doi: 10.1016/j.rmed.2013.09.014
-
(2014)
Respir. Med
, vol.108
, pp. 417-425
-
-
Aksamit, T.R.1
Philley, J.V.2
Griffith, D.E.3
-
2
-
-
70449705831
-
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
-
Barry, C. E. III, Boshoff, H. I., Dartois, V., Dick, T., Ehrt, S., Flynn, J., et al. (2009). The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat. Rev. Microbiol. 7, 845-855. doi: 10.1038/nrmicro2236
-
(2009)
Nat. Rev. Microbiol
, vol.7
, pp. 845-855
-
-
Barry, C.E.1
Boshoff, H.I.2
Dartois, V.3
Dick, T.4
Ehrt, S.5
Flynn, J.6
-
3
-
-
10044246303
-
Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets
-
Baurin, N., Aboul-Ela, F., Barril, X., Davis, B., Drysdale, M., Dymock, B., et al. (2004). Design and characterization of libraries of molecular fragments for use in NMR screening against protein targets. J. Chem. Inf. Comput. Sci. 44, 2157-2166. doi: 10.1021/ci049806z
-
(2004)
J. Chem. Inf. Comput. Sci
, vol.44
, pp. 2157-2166
-
-
Baurin, N.1
Aboul-Ela, F.2
Barril, X.3
Davis, B.4
Drysdale, M.5
Dymock, B.6
-
4
-
-
84857134246
-
High-throughput assessment of bacterial growth inhibition by optical density measurements
-
Campbell, J. (2011). High-throughput assessment of bacterial growth inhibition by optical density measurements. Curr. Protoc. Chem. Biol. 3:100115
-
(2011)
Curr. Protoc. Chem. Biol
, vol.3
-
-
Campbell, J.1
-
5
-
-
0141726877
-
A 'rule of three' for fragment-based lead discovery?
-
Congreve, M., Carr, R., Murray, C., and Jhoti, H. (2003). A 'rule of three' for fragment-based lead discovery? Drug Discov. Today 8, 876-877. doi: 10.1016/S1359-6446(03)02831-9
-
(2003)
Drug Discov. Today
, vol.8
, pp. 876-877
-
-
Congreve, M.1
Carr, R.2
Murray, C.3
Jhoti, H.4
-
6
-
-
84894068321
-
The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells
-
Dartois, V. (2014). The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells. Nat. Rev. Microbiol. 12, 159-167. doi: 10.1038/nrmicro3200
-
(2014)
Nat. Rev. Microbiol
, vol.12
, pp. 159-167
-
-
Dartois, V.1
-
7
-
-
77951549958
-
Clinical pharmacology and lesion penetrating properties of second-and third-line antituberculous agents used in the management of multidrug-resistant (MDR) and extensively-drug resistant (XDR) tuberculosis
-
Dartois, V., and Barry, C. E. (2010). Clinical pharmacology and lesion penetrating properties of second-and third-line antituberculous agents used in the management of multidrug-resistant (MDR) and extensively-drug resistant (XDR) tuberculosis. Curr. Clin. Pharmacol. 5, 96-114. doi: 10.2174/157488410791110797
-
(2010)
Curr. Clin. Pharmacol
, vol.5
, pp. 96-114
-
-
Dartois, V.1
Barry, C.E.2
-
8
-
-
84881367368
-
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis
-
Dartois, V., and Barry, C. E. III. (2013). A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis. Bioorg. Med. Chem. Lett. 23, 4741-4750. doi: 10.1016/j.bmcl.2013.07.006
-
(2013)
Bioorg. Med. Chem. Lett
, vol.23
, pp. 4741-4750
-
-
Dartois, V.1
Barry, C.E.2
-
9
-
-
0014039837
-
Drug-induced hemolysis
-
Dausset, J., and Contu, L. (1967). Drug-induced hemolysis. Annu. Rev. Med. 18, 55-70. doi: 10.1146/annurev.me.18.020167.000415
-
(1967)
Annu. Rev. Med
, vol.18
, pp. 55-70
-
-
Dausset, J.1
Contu, L.2
-
10
-
-
84890983264
-
'TB drug discovery from target identification to proof of concept studies, '
-
eds S. H. E. Kaufmann and P. van Helden (Weinheim: Wiley-VCH)
-
Dick, T., Dartois, V., Keller, T., and Matter, A. (2007). "TB drug discovery from target identification to proof of concept studies, "in Handbook of Tuberculosis: Clinics, Diagnostics, Therapy and Epidemiology, eds S. H. E. Kaufmann and P. van Helden (Weinheim: Wiley-VCH), 139-159.
-
(2007)
Handbook of Tuberculosis: Clinics, Diagnostics, Therapy and Epidemiology
, pp. 139-159
-
-
Dick, T.1
Dartois, V.2
Keller, T.3
Matter, A.4
-
11
-
-
0034609833
-
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
-
Ertl, P., Rohde, B., and Selzer, P. (2000). Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J. Med. Chem. 43, 3714-3717. doi: 10.1021/jm000942e
-
(2000)
J. Med. Chem
, vol.43
, pp. 3714-3717
-
-
Ertl, P.1
Rohde, B.2
Selzer, P.3
-
12
-
-
84904917797
-
Reactive dirty fragments: implications for tuberculosis drug discovery
-
Gopal, P., and Dick, T. (2014). Reactive dirty fragments: implications for tuberculosis drug discovery. Curr. Opin. Microbiol. 21, 7-12. doi: 10.1016/j.mib.2014.06.015
-
(2014)
Curr. Opin. Microbiol
, vol.21
, pp. 7-12
-
-
Gopal, P.1
Dick, T.2
-
13
-
-
84925533874
-
The new tuberculosis drug Perchlozone� shows cross-resistance with thiacetazone
-
Gopal, P., and Dick, T. (2015). The new tuberculosis drug Perchlozone� shows cross-resistance with thiacetazone. Int. J. Antimicrob. Agents 45, 430-433. doi: 10.1016/j.ijantimicag.2014.12.026
-
(2015)
Int. J. Antimicrob. Agents
, vol.45
, pp. 430-433
-
-
Gopal, P.1
Dick, T.2
-
14
-
-
79951824945
-
The talking Mycobacterium abscessus blues
-
Griffith, D. E. (2011). The talking Mycobacterium abscessus blues. Clin. Infect. Dis. 52, 572-574. doi: 10.1093/cid/ciq252
-
(2011)
Clin. Infect. Dis
, vol.52
, pp. 572-574
-
-
Griffith, D.E.1
-
15
-
-
33847050904
-
An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases
-
Griffith, D. E., Aksamit, T., Brown-Elliott, B. A., Catanzaro, A., Daley, C., Gordin, F., et al. (2007). An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am. J. Respir. Crit. Care Med. 175, 367-416. doi: 10.1164/rccm.200604-571ST
-
(2007)
Am. J. Respir. Crit. Care Med
, vol.175
, pp. 367-416
-
-
Griffith, D.E.1
Aksamit, T.2
Brown-Elliott, B.A.3
Catanzaro, A.4
Daley, C.5
Gordin, F.6
-
16
-
-
78650357755
-
Challenges of antibacterial discovery revisited
-
Gwynn, M. N., Portnoy, A., Rittenhouse, S. F., and Payne, D. J. (2010). Challenges of antibacterial discovery revisited. Ann. N. Y. Acad. Sci. 1213, 5-19. doi: 10.1111/j.1749-6632.2010.05828.x
-
(2010)
Ann. N. Y. Acad. Sci
, vol.1213
, pp. 5-19
-
-
Gwynn, M.N.1
Portnoy, A.2
Rittenhouse, S.F.3
Payne, D.J.4
-
17
-
-
84893307473
-
The role of ligand efficiency metrics in drug discovery
-
Hopkins, A. L., Keseru, G. M., Leeson, P. D., Rees, D. C., and Reynolds, C. H. (2014). The role of ligand efficiency metrics in drug discovery. Nat. Rev. Drug Discov. 13, 105-121. doi: 10.1038/nrd4163
-
(2014)
Nat. Rev. Drug Discov
, vol.13
, pp. 105-121
-
-
Hopkins, A.L.1
Keseru, G.M.2
Leeson, P.D.3
Rees, D.C.4
Reynolds, C.H.5
-
18
-
-
84928178295
-
Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents
-
Lakshminarayana, S. B., Huat, T. B., Ho, P. C., Manjunatha, U. H., Dartois, V., Dick, T., et al. (2015). Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents. J. Antimicrob. Chemother. 70, 857-867. doi: 10.1093/jac/dku457
-
(2015)
J. Antimicrob. Chemother
, vol.70
, pp. 857-867
-
-
Lakshminarayana, S.B.1
Huat, T.B.2
Ho, P.C.3
Manjunatha, U.H.4
Dartois, V.5
Dick, T.6
-
19
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
Lipinski, C. A. (2000). Drug-like properties and the causes of poor solubility and poor permeability. J. Pharmacol. Toxicol. Methods 44, 235-249. doi: 10.1016/S1056-8719(00)00107-6
-
(2000)
J. Pharmacol. Toxicol. Methods
, vol.44
, pp. 235-249
-
-
Lipinski, C.A.1
-
20
-
-
0034531320
-
Bactericidal activity of nitrofurans against growing and dormant Mycobacterium bovis BCG
-
Murugasu-Oei, B., and Dick, T. (2000). Bactericidal activity of nitrofurans against growing and dormant Mycobacterium bovis BCG. J. Antimicrob. Chemother. 46, 917-919. doi: 10.1093/jac/46.6.917
-
(2000)
J. Antimicrob. Chemother
, vol.46
, pp. 917-919
-
-
Murugasu-Oei, B.1
Dick, T.2
-
21
-
-
84858638893
-
Mycobacterium abscessus: a new antibiotic nightmare
-
Nessar, R., Cambau, E., Reyrat, J. M., Murray, A., and Gicquel, B. (2012). Mycobacterium abscessus: a new antibiotic nightmare. J. Antimicrob. Chemother. 67, 810-818. doi: 10.1093/jac/dkr578
-
(2012)
J. Antimicrob. Chemother
, vol.67
, pp. 810-818
-
-
Nessar, R.1
Cambau, E.2
Reyrat, J.M.3
Murray, A.4
Gicquel, B.5
-
22
-
-
84926178390
-
Nontuberculous mycobacteria in cystic fibrosis and non-cystic fibrosis bronchiectasis
-
Park, I. K., and Olivier, K. N. (2015). Nontuberculous mycobacteria in cystic fibrosis and non-cystic fibrosis bronchiectasis. Semin. Respir. Crit. Care Med. 36, 217-224. doi: 10.1055/s-0035-1546751
-
(2015)
Semin. Respir. Crit. Care Med
, vol.36
, pp. 217-224
-
-
Park, I.K.1
Olivier, K.N.2
-
23
-
-
33845903833
-
Drugs for bad bugs: confronting the challenges of antibacterial discovery
-
Payne, D. J., Gwynn, M. N., Holmes, D. J., and Pompliano, D. L. (2007). Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6, 29-40. doi: 10.1038/nrd2201
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
Pompliano, D.L.4
-
24
-
-
84979928049
-
'Cell viability assays, '
-
eds G. S. Sittampalam, N. P. Coussens, H. Nelson, M. Arkin, D. Auld, C. Austin, et al. (Rockville, MD: Bethesda)
-
Riss, T. L., Moravec, R. A., Niles, A. L., Benink, H. A., Worzella, T. J., Minor, L., et al. (2004). "Cell viability assays, "in Assay Guidance Manual, eds G. S. Sittampalam, N. P. Coussens, H. Nelson, M. Arkin, D. Auld, C. Austin, et al. (Rockville, MD: Bethesda).
-
(2004)
Assay Guidance Manual
-
-
Riss, T.L.1
Moravec, R.A.2
Niles, A.L.3
Benink, H.A.4
Worzella, T.J.5
Minor, L.6
-
25
-
-
84862869077
-
Fragment-based approaches in drug discovery and chemical biology
-
Scott, D. E., Coyne, A. G., Hudson, S. A., and Abell, C. (2012). Fragment-based approaches in drug discovery and chemical biology. Biochemistry 51, 4990-5003. doi: 10.1021/bi3005126
-
(2012)
Biochemistry
, vol.51
, pp. 4990-5003
-
-
Scott, D.E.1
Coyne, A.G.2
Hudson, S.A.3
Abell, C.4
-
26
-
-
84969255804
-
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives
-
Via, L. E., Savic, R., Weiner, D. M., Zimmerman, M. D., Prideaux, B., Irwin, S. M., et al. (2015). Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives. ACS Infect. Dis. 1, 203-214. doi: 10.1021/id500028m
-
(2015)
ACS Infect. Dis
, vol.1
, pp. 203-214
-
-
Via, L.E.1
Savic, R.2
Weiner, D.M.3
Zimmerman, M.D.4
Prideaux, B.5
Irwin, S.M.6
-
27
-
-
84935892144
-
-
Geneva: World Health Organization
-
WHO (2015). Global Tuberculosis Report 2015. Geneva: World Health Organization.
-
(2015)
Global Tuberculosis Report 2015
-
-
|