-
1
-
-
0024323330
-
A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer?
-
[1] LeRoy, E.C., Smith, E.A., Kahaleh, M.B., Trojanowska, M., Silver, R.M., A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer?. Arthritis Rheum. 32 (1989), 817–825.
-
(1989)
Arthritis Rheum.
, vol.32
, pp. 817-825
-
-
LeRoy, E.C.1
Smith, E.A.2
Kahaleh, M.B.3
Trojanowska, M.4
Silver, R.M.5
-
2
-
-
0016302998
-
Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast
-
[2] LeRoy, E.C., Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast. J. Clin. Invest. 54 (1974), 880–889.
-
(1974)
J. Clin. Invest.
, vol.54
, pp. 880-889
-
-
LeRoy, E.C.1
-
3
-
-
0022493764
-
Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis
-
[3] Jimenez, S.A., Feldman, G., Bashey, R.I., Bienkowski, R., Rosenbloom, J., Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis. Biochem. J. 237 (1986), 837–843.
-
(1986)
Biochem. J.
, vol.237
, pp. 837-843
-
-
Jimenez, S.A.1
Feldman, G.2
Bashey, R.I.3
Bienkowski, R.4
Rosenbloom, J.5
-
4
-
-
0026666859
-
Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts
-
[4] Kikuchi, K., Smith, E.A., LeRoy, E.C., Trojanowska, M., Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts. Biochem. Biophys. Res. Commun. 187 (1992), 45–50.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 45-50
-
-
Kikuchi, K.1
Smith, E.A.2
LeRoy, E.C.3
Trojanowska, M.4
-
5
-
-
0035089825
-
Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor β receptors
-
[5] Ihn, H., Yamane, K., Kubo, M., Tamaki, K., Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor β receptors. Arthritis Rheum. 44 (2001), 474–480.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 474-480
-
-
Ihn, H.1
Yamane, K.2
Kubo, M.3
Tamaki, K.4
-
6
-
-
0036448477
-
The role of TGF-β signaling in the pathogenesis of fibrosis in scleroderma
-
[6] Ihn, H., The role of TGF-β signaling in the pathogenesis of fibrosis in scleroderma. Arch. Immunol. Ther. Exp. 50 (2002), 325–331.
-
(2002)
Arch. Immunol. Ther. Exp.
, vol.50
, pp. 325-331
-
-
Ihn, H.1
-
7
-
-
28244449083
-
Increased expression of integrin αvβ3 contributes to the establishment of autocrine TGF-β signaling in scleroderma fibroblasts
-
[7] Asano, Y., Ihn, H., Yamane, K., Jinnin, M., Mimura, Y., Tamaki, K., Increased expression of integrin αvβ3 contributes to the establishment of autocrine TGF-β signaling in scleroderma fibroblasts. J. Immunol. 175 (2005), 7708–7718.
-
(2005)
J. Immunol.
, vol.175
, pp. 7708-7718
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Mimura, Y.5
Tamaki, K.6
-
8
-
-
25444501226
-
Involvement of αvβ5 integrin-mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts
-
[8] Asano, Y., Ihn, H., Yamane, K., Jinnin, M., Mimura, Y., Tamaki, K., Involvement of αvβ5 integrin-mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts. Arthritis Rheum. 52 (2005), 2897–2905.
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 2897-2905
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Mimura, Y.5
Tamaki, K.6
-
9
-
-
33144458448
-
Increased expression of integrin αvβ5 induces the myofibroblastic differentiation of dermal fibroblasts
-
[9] Asano, Y., Ihn, H., Yamane, K., Jinnin, M., Tamaki, K., Increased expression of integrin αvβ5 induces the myofibroblastic differentiation of dermal fibroblasts. Am. J. Pathol. 168 (2006), 499–510.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 499-510
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Tamaki, K.5
-
10
-
-
76249133692
-
Defined factors induce reprogramming of gastrointestinal cancer cells
-
[10] Miyoshi, N., Ishii, H., Nagai, K., Hoshino, H., Mimori, K., Tanaka, F., et al. Defined factors induce reprogramming of gastrointestinal cancer cells. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 40–45.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 40-45
-
-
Miyoshi, N.1
Ishii, H.2
Nagai, K.3
Hoshino, H.4
Mimori, K.5
Tanaka, F.6
-
11
-
-
84904608539
-
Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome
-
[11] Kobayashi, J., Yoshida, M., Tarui, S., Hirata, M., Nagai, Y., Kasahara, S., et al. Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome. PLoS One, 9, 2014, e102796.
-
(2014)
PLoS One
, vol.9
, pp. e102796
-
-
Kobayashi, J.1
Yoshida, M.2
Tarui, S.3
Hirata, M.4
Nagai, Y.5
Kasahara, S.6
-
12
-
-
84859414443
-
TGF-β-mediated downregulation of microRNA-196a contributes to the constitutive upregulated type I collagen expression in scleroderma dermal fibroblasts
-
[12] Honda, N., Jinnin, M., Kajihara, I., Makino, T., Makino, K., Masuguchi, S., et al. TGF-β-mediated downregulation of microRNA-196a contributes to the constitutive upregulated type I collagen expression in scleroderma dermal fibroblasts. J. Immunol. 188 (2012), 3323–3331.
-
(2012)
J. Immunol.
, vol.188
, pp. 3323-3331
-
-
Honda, N.1
Jinnin, M.2
Kajihara, I.3
Makino, T.4
Makino, K.5
Masuguchi, S.6
-
13
-
-
0018887574
-
-
Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee, Preliminary criteria for the classification of systemic sclerosis (scleroderma) Arthritis Rheum. 23 (1980) 581–590.
-
[13] Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee, Preliminary criteria for the classification of systemic sclerosis (scleroderma) Arthritis Rheum. 23 (1980) 581–590.
-
-
-
-
14
-
-
70450265981
-
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
-
[14] Fusaki, N., Ban, H., Nishiyama, A., Saeki, K., Hasegawa, M., Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc. Jpn. Acad. Ser. B. Phys. Biol. Sci. 85 (2009), 348–362.
-
(2009)
Proc. Jpn. Acad. Ser. B. Phys. Biol. Sci.
, vol.85
, pp. 348-362
-
-
Fusaki, N.1
Ban, H.2
Nishiyama, A.3
Saeki, K.4
Hasegawa, M.5
-
15
-
-
80052157957
-
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
-
[15] Ban, H., Nishishita, N., Fusaki, N., Tabata, T., Saeki, K., Shikamura, M., et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 14234–14239.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 14234-14239
-
-
Ban, H.1
Nishishita, N.2
Fusaki, N.3
Tabata, T.4
Saeki, K.5
Shikamura, M.6
-
16
-
-
84893876904
-
Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells
-
[16] Isono, K., Jono, H., Ohya, Y., Shiraki, N., Yamazoe, T., Sugasaki, A., et al. Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells. Stem Cell Res. 12 (2014), 574–583.
-
(2014)
Stem Cell Res.
, vol.12
, pp. 574-583
-
-
Isono, K.1
Jono, H.2
Ohya, Y.3
Shiraki, N.4
Yamazoe, T.5
Sugasaki, A.6
-
17
-
-
84885396246
-
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs)
-
[17] Itoh, M., Umegaki-Arao, N., Guo, Z., Liu, L., Higgins, C.A., Christiano, A.M., Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs). PLoS One, 8, 2013, e77673.
-
(2013)
PLoS One
, vol.8
, pp. e77673
-
-
Itoh, M.1
Umegaki-Arao, N.2
Guo, Z.3
Liu, L.4
Higgins, C.A.5
Christiano, A.M.6
-
18
-
-
44349175948
-
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population
-
[18] Yang, L., Soonpaa, M.H., Adler, E.D., Roepke, T.K., Kattman, S.J., Kennedy, M., et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature 453 (2008), 524–528.
-
(2008)
Nature
, vol.453
, pp. 524-528
-
-
Yang, L.1
Soonpaa, M.H.2
Adler, E.D.3
Roepke, T.K.4
Kattman, S.J.5
Kennedy, M.6
-
19
-
-
85006325457
-
The expression profile of the toll-like receptor family in scleroderma dermal fibroblasts
-
(S-4-9)
-
[19] Sakoguchi, A., Nakayama, W., Jinnin, M., Wang, Z., Yamane, K., Aoi, J., et al. The expression profile of the toll-like receptor family in scleroderma dermal fibroblasts. Clin. Exp. Rheumatol., 32, 2014 (S-4-9).
-
(2014)
Clin. Exp. Rheumatol.
, vol.32
-
-
Sakoguchi, A.1
Nakayama, W.2
Jinnin, M.3
Wang, Z.4
Yamane, K.5
Aoi, J.6
-
20
-
-
84901609119
-
Decreased IL-20 expression in scleroderma skin contributes to cutaneous fibrosis
-
[20] Kudo, H., Jinnin, M., Asano, Y., Trojanowska, M., Nakayama, W., Inoue, K., et al. Decreased IL-20 expression in scleroderma skin contributes to cutaneous fibrosis. Arthritis Rheumatol. 66 (2014), 1636–1647.
-
(2014)
Arthritis Rheumatol.
, vol.66
, pp. 1636-1647
-
-
Kudo, H.1
Jinnin, M.2
Asano, Y.3
Trojanowska, M.4
Nakayama, W.5
Inoue, K.6
-
21
-
-
84917709166
-
New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood
-
[21] Fujie, Y., Fusaki, N., Katayama, T., Hamasaki, M., Soejima, Y., Soga, M., et al. New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood. PLoS One, 9, 2014, e113052.
-
(2014)
PLoS One
, vol.9
, pp. e113052
-
-
Fujie, Y.1
Fusaki, N.2
Katayama, T.3
Hamasaki, M.4
Soejima, Y.5
Soga, M.6
-
22
-
-
11144347711
-
Regulation of fibrogenic/fibrolytic genes by platelet-derived growth factor C a novel growth factor, in human dermal fibroblasts
-
[22] Jinnin, M., Ihn, H., Mimura, Y., Asano, Y., Yamane, K., Tamaki, K., Regulation of fibrogenic/fibrolytic genes by platelet-derived growth factor C a novel growth factor, in human dermal fibroblasts. J. Cell Physiol. 202 (2005), 510–517.
-
(2005)
J. Cell Physiol.
, vol.202
, pp. 510-517
-
-
Jinnin, M.1
Ihn, H.2
Mimura, Y.3
Asano, Y.4
Yamane, K.5
Tamaki, K.6
-
23
-
-
84888125258
-
Role of c-Jun N-terminal kinase isoforms in the cellular activity of melanoma cell lines
-
[23] Kogushi-Nishi, H., Jinnin, M., Kobayashi, Y., Muchemwa, F.C., Hirano, A., Makino, T., et al. Role of c-Jun N-terminal kinase isoforms in the cellular activity of melanoma cell lines. Clin. Exp. Dermatol. 38 (2013), 890–896.
-
(2013)
Clin. Exp. Dermatol.
, vol.38
, pp. 890-896
-
-
Kogushi-Nishi, H.1
Jinnin, M.2
Kobayashi, Y.3
Muchemwa, F.C.4
Hirano, A.5
Makino, T.6
-
24
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
[24] Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007), 861–872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
25
-
-
84885331524
-
Increased expression of S100A8 and S100A9 in patients with diffuse cutaneous systemic sclerosis. A correlation with organ involvement and immunological abnormalities
-
[25] Xu, X., Wu, W.Y., Tu, W.Z., Chu, H.Y., Zhu, X.X., Liang, M.R., et al. Increased expression of S100A8 and S100A9 in patients with diffuse cutaneous systemic sclerosis. A correlation with organ involvement and immunological abnormalities. Clin. Rheumatol. 32 (2013), 1501–1510.
-
(2013)
Clin. Rheumatol.
, vol.32
, pp. 1501-1510
-
-
Xu, X.1
Wu, W.Y.2
Tu, W.Z.3
Chu, H.Y.4
Zhu, X.X.5
Liang, M.R.6
-
26
-
-
0037133596
-
Deficient Smad7 expression: a putative molecular defect in scleroderma
-
[26] Dong, C., Zhu, S., Wang, T., Yoon, W., Li, Z., Alvarez, R.J., et al. Deficient Smad7 expression: a putative molecular defect in scleroderma. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 3908–3913.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 3908-3913
-
-
Dong, C.1
Zhu, S.2
Wang, T.3
Yoon, W.4
Li, Z.5
Alvarez, R.J.6
-
27
-
-
0038004796
-
Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
-
[27] Mori, Y., Chen, S.J., Varga, J., Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts. Arthritis Rheum. 48 (2003), 1964–1978.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 1964-1978
-
-
Mori, Y.1
Chen, S.J.2
Varga, J.3
-
28
-
-
85047692249
-
Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
-
[28] Asano, Y., Ihn, H., Yamane, K., Kubo, M., Tamaki, K., Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts. J. Clin. Invest. 113 (2004), 253–264.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 253-264
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Kubo, M.4
Tamaki, K.5
-
29
-
-
84934965666
-
Leri's pleonosteosis a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis
-
[29] Banka, S., Cain, S.A., Carim, S., Daly, S.B., Urquhart, J.E., Erdem, G., et al. Leri's pleonosteosis a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis. Ann. Rheum. Dis. 74 (2015), 1249–1256.
-
(2015)
Ann. Rheum. Dis.
, vol.74
, pp. 1249-1256
-
-
Banka, S.1
Cain, S.A.2
Carim, S.3
Daly, S.B.4
Urquhart, J.E.5
Erdem, G.6
-
30
-
-
0028178471
-
Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
-
[30] Weller, M., Constam, D.B., Malipiero, U., Fontana, A., Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur. J. Immunol. 24 (1994), 1293–1300.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1293-1300
-
-
Weller, M.1
Constam, D.B.2
Malipiero, U.3
Fontana, A.4
-
31
-
-
3543094383
-
Augmented production of transforming growth factor-β by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
-
[31] Hasegawa, M., Sato, S., Takehara, K., Augmented production of transforming growth factor-β by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. Arch. Dermatol. Res. 296 (2004), 89–93.
-
(2004)
Arch. Dermatol. Res.
, vol.296
, pp. 89-93
-
-
Hasegawa, M.1
Sato, S.2
Takehara, K.3
-
32
-
-
20744455828
-
Diminished transforming growth factor β2 production leads to increased expression of a profibrotic procollagen α2 type I messenger RNA variant in embryonic fibroblasts of UCD-200 chickens, a model for systemic sclerosis
-
[32] Prelog, M., Scheidegger, P., Peter, S., Gershwin, M.E., Wick, G., Sgonc, R., Diminished transforming growth factor β2 production leads to increased expression of a profibrotic procollagen α2 type I messenger RNA variant in embryonic fibroblasts of UCD-200 chickens, a model for systemic sclerosis. Arthritis Rheum. 52 (2005), 1804–1811.
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 1804-1811
-
-
Prelog, M.1
Scheidegger, P.2
Peter, S.3
Gershwin, M.E.4
Wick, G.5
Sgonc, R.6
-
33
-
-
0019841405
-
Variability in collagen and fibronectin synthesis by scleroderma fibroblasts in primary culture
-
[33] Fleischmajer, R., Perlish, J.S., Krieg, T., Timpl, R., Variability in collagen and fibronectin synthesis by scleroderma fibroblasts in primary culture. J. Invest. Dermatol. 76 (1981), 400–403.
-
(1981)
J. Invest. Dermatol.
, vol.76
, pp. 400-403
-
-
Fleischmajer, R.1
Perlish, J.S.2
Krieg, T.3
Timpl, R.4
-
34
-
-
17844395977
-
Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-β signaling in cultured scleroderma fibroblasts
-
[34] Mimura, Y., Ihn, H., Jinnin, M., Asano, Y., Yamane, K., Tamaki, K., Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-β signaling in cultured scleroderma fibroblasts. Am. J. Pathol. 166 (2005), 1451–1463.
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 1451-1463
-
-
Mimura, Y.1
Ihn, H.2
Jinnin, M.3
Asano, Y.4
Yamane, K.5
Tamaki, K.6
-
35
-
-
84877726032
-
Scleroderma dermal fibroblasts overexpress vascular endothelial growth factor due to autocrine transforming growth factor β signaling
-
[35] Kajihara, I., Jinnin, M., Honda, N., Makino, K., Makino, T., Masuguchi, S., et al. Scleroderma dermal fibroblasts overexpress vascular endothelial growth factor due to autocrine transforming growth factor β signaling. Mod. Rheumatol. 23 (2012), 516–524.
-
(2012)
Mod. Rheumatol.
, vol.23
, pp. 516-524
-
-
Kajihara, I.1
Jinnin, M.2
Honda, N.3
Makino, K.4
Makino, T.5
Masuguchi, S.6
-
36
-
-
77949810710
-
Serum levels of soluble vascular endothelial growth factor receptor-2 in patients with systemic sclerosis
-
[36] Jinnin, M., Makino, T., Kajihara, I., Honda, N., Makino, K., Ogata, A., et al. Serum levels of soluble vascular endothelial growth factor receptor-2 in patients with systemic sclerosis. Br. J. Dermatol. 162 (2010), 751–758.
-
(2010)
Br. J. Dermatol.
, vol.162
, pp. 751-758
-
-
Jinnin, M.1
Makino, T.2
Kajihara, I.3
Honda, N.4
Makino, K.5
Ogata, A.6
|