메뉴 건너뛰기




Volumn 136, Issue 9, 2016, Pages 1768-1780

Intrinsic Defect in Keratinocyte Function Leads to Inflammation in Hidradenitis Suppurativa

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CUTANEOUS T CELL ATTRACTING CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; PATTERN RECOGNITION RECEPTOR; POLYPEPTIDE ANTIBIOTIC AGENT; RANTES; CYTOKINE; RNA;

EID: 84992520731     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2016.04.036     Document Type: Article
Times cited : (135)

References (49)
  • 1
    • 76549260925 scopus 로고    scopus 로고
    • Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells
    • Aasen, T., Izpisua Belmonte, J.C., Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells. Nat Protoc 5 (2010), 371–382.
    • (2010) Nat Protoc , vol.5 , pp. 371-382
    • Aasen, T.1    Izpisua Belmonte, J.C.2
  • 2
    • 0029094467 scopus 로고
    • The pathogenesis of hidradenitis suppurativa: a closer look at apocrine and apoeccrine glands
    • Attanoos, R.L., Appleton, M.A., Douglas-Jones, A.G., The pathogenesis of hidradenitis suppurativa: a closer look at apocrine and apoeccrine glands. Br J Dermatol 133 (1995), 254–258.
    • (1995) Br J Dermatol , vol.133 , pp. 254-258
    • Attanoos, R.L.1    Appleton, M.A.2    Douglas-Jones, A.G.3
  • 3
    • 61649085104 scopus 로고    scopus 로고
    • FlexArray: A statistical data analysis software for gene expression microarrays
    • Genome Quebec Montreal, Canada
    • Blazejczyk, M., Miron, M., Nadon, R., FlexArray: A statistical data analysis software for gene expression microarrays. 2007, Genome Quebec, Montreal, Canada.
    • (2007)
    • Blazejczyk, M.1    Miron, M.2    Nadon, R.3
  • 4
    • 0029907640 scopus 로고    scopus 로고
    • Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions
    • Boer, J., Weltevreden, E.F., Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions. Br J Dermatol 135 (1996), 721–725.
    • (1996) Br J Dermatol , vol.135 , pp. 721-725
    • Boer, J.1    Weltevreden, E.F.2
  • 5
    • 84930389636 scopus 로고    scopus 로고
    • Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity
    • Burkett, P.R., Meyer zu Horste, G., Kuchroo, V.K., Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity. J Clin Invest 125 (2015), 2211–2219.
    • (2015) J Clin Invest , vol.125 , pp. 2211-2219
    • Burkett, P.R.1    Meyer zu Horste, G.2    Kuchroo, V.K.3
  • 6
    • 33646036415 scopus 로고    scopus 로고
    • CD4+CD25+ T cells in skin lesions of patients with cutaneous leishmaniasis exhibit phenotypic and functional characteristics of natural regulatory T cells
    • Campanelli, A.P., Roselino, A.M., Cavassani, K.A., Pereira, M.S., Mortara, R.A., Brodskyn, C.I., et al. CD4+CD25+ T cells in skin lesions of patients with cutaneous leishmaniasis exhibit phenotypic and functional characteristics of natural regulatory T cells. J Infect Dis 193 (2006), 1313–1322.
    • (2006) J Infect Dis , vol.193 , pp. 1313-1322
    • Campanelli, A.P.1    Roselino, A.M.2    Cavassani, K.A.3    Pereira, M.S.4    Mortara, R.A.5    Brodskyn, C.I.6
  • 7
    • 67349262339 scopus 로고    scopus 로고
    • Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity
    • Canoui-Poitrine, F., Revuz, J.E., Wolkenstein, P., Viallette, C., Gabison, G., Pouget, F., et al. Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity. J Am Acad Dermatol 61 (2009), 51–57.
    • (2009) J Am Acad Dermatol , vol.61 , pp. 51-57
    • Canoui-Poitrine, F.1    Revuz, J.E.2    Wolkenstein, P.3    Viallette, C.4    Gabison, G.5    Pouget, F.6
  • 8
    • 84856166958 scopus 로고    scopus 로고
    • Hidradenitis suppurativa: the role of deficient cutaneous innate immunity
    • Dreno, B., Khammari, A., Brocard, A., Moyse, D., Blouin, E., Guillet, G., et al. Hidradenitis suppurativa: the role of deficient cutaneous innate immunity. Arch Dermatol 148 (2012), 182–186.
    • (2012) Arch Dermatol , vol.148 , pp. 182-186
    • Dreno, B.1    Khammari, A.2    Brocard, A.3    Moyse, D.4    Blouin, E.5    Guillet, G.6
  • 9
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen, T., Geiger, R., Jarrossay, D., Lanzavecchia, A., Sallusto, F., Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 10 (2009), 857–863.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3    Lanzavecchia, A.4    Sallusto, F.5
  • 10
    • 0024828720 scopus 로고
    • In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation
    • Endres, S., Cannon, J.G., Ghorbani, R., Dempsey, R.A., Sisson, S.D., Lonnemann, G., et al. In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation. Eur J Immunol 19 (1989), 2327–2333.
    • (1989) Eur J Immunol , vol.19 , pp. 2327-2333
    • Endres, S.1    Cannon, J.G.2    Ghorbani, R.3    Dempsey, R.A.4    Sisson, S.D.5    Lonnemann, G.6
  • 11
    • 84862862332 scopus 로고    scopus 로고
    • Epithelial antimicrobial defence of the skin and intestine
    • Gallo, R.L., Hooper, L.V., Epithelial antimicrobial defence of the skin and intestine. Nat Rev Immunol 12 (2012), 503–516.
    • (2012) Nat Rev Immunol , vol.12 , pp. 503-516
    • Gallo, R.L.1    Hooper, L.V.2
  • 12
    • 33745580349 scopus 로고    scopus 로고
    • Inversa acne (hidradenitis suppurativa): a case report and identification of the locus at chromosome 1p21.1-1q25.3
    • Gao, M., Wang, P.G., Cui, Y., Yang, S., Zhang, Y.H., Lin, D., et al. Inversa acne (hidradenitis suppurativa): a case report and identification of the locus at chromosome 1p21.1-1q25.3. J Invest Dermatol 126 (2006), 1302–1306.
    • (2006) J Invest Dermatol , vol.126 , pp. 1302-1306
    • Gao, M.1    Wang, P.G.2    Cui, Y.3    Yang, S.4    Zhang, Y.H.5    Lin, D.6
  • 13
    • 69349083243 scopus 로고    scopus 로고
    • Combination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patients
    • Gener, G., Canoui-Poitrine, F., Revuz, J.E., Faye, O., Poli, F., Gabison, G., et al. Combination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patients. Dermatology 219 (2009), 148–154.
    • (2009) Dermatology , vol.219 , pp. 148-154
    • Gener, G.1    Canoui-Poitrine, F.2    Revuz, J.E.3    Faye, O.4    Poli, F.5    Gabison, G.6
  • 15
    • 84930679365 scopus 로고    scopus 로고
    • Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis
    • Harbour, S.N., Maynard, C.L., Zindl, C.L., Schoeb, T.R., Weaver, C.T., Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis. Proc Natl Acad Sci USA 112 (2015), 7061–7066.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 7061-7066
    • Harbour, S.N.1    Maynard, C.L.2    Zindl, C.L.3    Schoeb, T.R.4    Weaver, C.T.5
  • 17
    • 84906790706 scopus 로고    scopus 로고
    • Microbiology of hidradenitis suppurativa (acne inversa): a histological study of 27 patients
    • Jahns, A.C., Killasli, H., Nosek, D., Lundskog, B., Lenngren, A., Muratova, Z., et al. Microbiology of hidradenitis suppurativa (acne inversa): a histological study of 27 patients. APMIS 122 (2014), 804–809.
    • (2014) APMIS , vol.122 , pp. 804-809
    • Jahns, A.C.1    Killasli, H.2    Nosek, D.3    Lundskog, B.4    Lenngren, A.5    Muratova, Z.6
  • 18
    • 84856007016 scopus 로고    scopus 로고
    • Clinical practice. Hidradenitis suppurativa
    • Jemec, G.B.E., Clinical practice. Hidradenitis suppurativa. N Engl J Med 366 (2012), 158–164.
    • (2012) N Engl J Med , vol.366 , pp. 158-164
    • Jemec, G.B.E.1
  • 19
    • 79951678758 scopus 로고    scopus 로고
    • Efficacy of rifampin-moxifloxacin-metronidazole combination therapy in hidradenitis suppurativa
    • Join-Lambert, O., Coignard, H., Jais, J.P., Guet-Revillet, H., Poiree, S., Fraitag, S., et al. Efficacy of rifampin-moxifloxacin-metronidazole combination therapy in hidradenitis suppurativa. Dermatology 222 (2011), 49–58.
    • (2011) Dermatology , vol.222 , pp. 49-58
    • Join-Lambert, O.1    Coignard, H.2    Jais, J.P.3    Guet-Revillet, H.4    Poiree, S.5    Fraitag, S.6
  • 21
    • 84862676582 scopus 로고    scopus 로고
    • Considering hidradenitis suppurativa as a bacterial biofilm disease
    • Kathju, S., Lasko, L.A., Stoodley, P., Considering hidradenitis suppurativa as a bacterial biofilm disease. FEMS Immunol Med Microbiol 65 (2012), 385–389.
    • (2012) FEMS Immunol Med Microbiol , vol.65 , pp. 385-389
    • Kathju, S.1    Lasko, L.A.2    Stoodley, P.3
  • 22
    • 84927590232 scopus 로고    scopus 로고
    • Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients
    • Kok, A., Hocqueloux, L., Hocini, H., Carriere, M., Lefrou, L., Guguin, A., et al. Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients. Mucosal Immunol 8 (2015), 127–140.
    • (2015) Mucosal Immunol , vol.8 , pp. 127-140
    • Kok, A.1    Hocqueloux, L.2    Hocini, H.3    Carriere, M.4    Lefrou, L.5    Guguin, A.6
  • 23
    • 0033013853 scopus 로고    scopus 로고
    • Coagulase-negative staphylococci are the most common bacteria found in cultures from the deep portions of hidradenitis suppurativa lesions, as obtained by carbon dioxide laser surgery
    • Lapins, J., Jarstrand, C., Emtestam, L., Coagulase-negative staphylococci are the most common bacteria found in cultures from the deep portions of hidradenitis suppurativa lesions, as obtained by carbon dioxide laser surgery. Br J Dermatol 140 (1999), 90–95.
    • (1999) Br J Dermatol , vol.140 , pp. 90-95
    • Lapins, J.1    Jarstrand, C.2    Emtestam, L.3
  • 24
    • 84949977353 scopus 로고    scopus 로고
    • Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa
    • Lima, A.L., Karl, I., Giner, T., Poppe, H., Schmidt, M., Presser, D., et al. Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa. Br J Dermatol 174 (2016), 514–521.
    • (2016) Br J Dermatol , vol.174 , pp. 514-521
    • Lima, A.L.1    Karl, I.2    Giner, T.3    Poppe, H.4    Schmidt, M.5    Presser, D.6
  • 25
    • 33645809372 scopus 로고    scopus 로고
    • Clindamycin and rifampicin combination therapy for hidradenitis suppurativa
    • Mendonca, C.O., Griffiths, C.E., Clindamycin and rifampicin combination therapy for hidradenitis suppurativa. Br J Dermatol 154 (2006), 977–978.
    • (2006) Br J Dermatol , vol.154 , pp. 977-978
    • Mendonca, C.O.1    Griffiths, C.E.2
  • 26
    • 84893638135 scopus 로고    scopus 로고
    • Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells
    • Murano, T., Okamoto, R., Ito, G., Nakata, T., Hibiya, S., Shimizu, H., et al. Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells. Biochem Biophys Res Commun 443 (2014), 840–846.
    • (2014) Biochem Biophys Res Commun , vol.443 , pp. 840-846
    • Murano, T.1    Okamoto, R.2    Ito, G.3    Nakata, T.4    Hibiya, S.5    Shimizu, H.6
  • 27
    • 84856864352 scopus 로고    scopus 로고
    • Antimicrobial peptides: old molecules with new ideas
    • Nakatsuji, T., Gallo, R.L., Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol 132 (2012), 887–895.
    • (2012) J Invest Dermatol , vol.132 , pp. 887-895
    • Nakatsuji, T.1    Gallo, R.L.2
  • 29
    • 0030839767 scopus 로고    scopus 로고
    • Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family
    • Oettgen, P., Alani, R.M., Barcinski, M.A., Brown, L., Akbarali, Y., Boltax, J., et al. Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. Mol Cell Biol 17 (1997), 4419–4433.
    • (1997) Mol Cell Biol , vol.17 , pp. 4419-4433
    • Oettgen, P.1    Alani, R.M.2    Barcinski, M.A.3    Brown, L.4    Akbarali, Y.5    Boltax, J.6
  • 30
  • 31
    • 84866375243 scopus 로고    scopus 로고
    • Mutations in the gamma-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa)
    • Pink, A.E., Simpson, M.A., Desai, N., Dafou, D., Hills, A., Mortimer, P., et al. Mutations in the gamma-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa). J Invest Dermatol 132 (2012), 2459–2461.
    • (2012) J Invest Dermatol , vol.132 , pp. 2459-2461
    • Pink, A.E.1    Simpson, M.A.2    Desai, N.3    Dafou, D.4    Hills, A.5    Mortimer, P.6
  • 32
    • 84892536761 scopus 로고    scopus 로고
    • Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids
    • Ramesh, R., Kozhaya, L., McKevitt, K., Djuretic, I.M., Carlson, T.J., Quintero, M.A., et al. Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids. J Exp Med 211 (2014), 89–104.
    • (2014) J Exp Med , vol.211 , pp. 89-104
    • Ramesh, R.1    Kozhaya, L.2    McKevitt, K.3    Djuretic, I.M.4    Carlson, T.J.5    Quintero, M.A.6
  • 33
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan, A., Talora, C., Okuyama, R., Nicolas, M., Mammucari, C., Oh, H., et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 20 (2001), 3427–3436.
    • (2001) EMBO J , vol.20 , pp. 3427-3436
    • Rangarajan, A.1    Talora, C.2    Okuyama, R.3    Nicolas, M.4    Mammucari, C.5    Oh, H.6
  • 34
    • 51349113269 scopus 로고    scopus 로고
    • Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies
    • Revuz, J.E., Canoui-Poitrine, F., Wolkenstein, P., Viallette, C., Gabison, G., Pouget, F., et al. Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol 59 (2008), 596–601.
    • (2008) J Am Acad Dermatol , vol.59 , pp. 596-601
    • Revuz, J.E.1    Canoui-Poitrine, F.2    Wolkenstein, P.3    Viallette, C.4    Gabison, G.5    Pouget, F.6
  • 37
    • 33751550191 scopus 로고    scopus 로고
    • Bacteraemia in patients with hidradenitis suppurativa undergoing carbon dioxide laser surgery: detection and quantification of bacteria by lysis-filtration
    • Sartorius, K., Lapins, J., Jalal, S., Emtestam, L., Hedberg, M., Bacteraemia in patients with hidradenitis suppurativa undergoing carbon dioxide laser surgery: detection and quantification of bacteria by lysis-filtration. Dermatology 213 (2006), 305–312.
    • (2006) Dermatology , vol.213 , pp. 305-312
    • Sartorius, K.1    Lapins, J.2    Jalal, S.3    Emtestam, L.4    Hedberg, M.5
  • 38
    • 0033624673 scopus 로고    scopus 로고
    • Nuclear factor kappaB subunits induce epithelial cell growth arrest
    • Seitz, C.S., Deng, H., Hinata, K., Lin, Q., Khavari, P.A., Nuclear factor kappaB subunits induce epithelial cell growth arrest. Cancer Res 60 (2000), 4085–4092.
    • (2000) Cancer Res , vol.60 , pp. 4085-4092
    • Seitz, C.S.1    Deng, H.2    Hinata, K.3    Lin, Q.4    Khavari, P.A.5
  • 39
    • 0032477945 scopus 로고    scopus 로고
    • Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB
    • Seitz, C.S., Lin, Q., Deng, H., Khavari, P.A., Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proc Natl Acad Sci USA 95 (1998), 2307–2312.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2307-2312
    • Seitz, C.S.1    Lin, Q.2    Deng, H.3    Khavari, P.A.4
  • 40
    • 84871769569 scopus 로고    scopus 로고
    • Hidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatments
    • van der Zee, H.H., Laman, J.D., Boer, J., Prens, E.P., Hidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatments. Exp Dermatol 21 (2012), 735–739.
    • (2012) Exp Dermatol , vol.21 , pp. 735-739
    • van der Zee, H.H.1    Laman, J.D.2    Boer, J.3    Prens, E.P.4
  • 41
    • 84914161660 scopus 로고    scopus 로고
    • The prevalence of inverse recurrent suppuration: a population-based study of possible hidradenitis suppurativa
    • Vinding, G.R., Miller, I.M., Zarchi, K., Ibler, K.S., Ellervik, C., Jemec, G.B., The prevalence of inverse recurrent suppuration: a population-based study of possible hidradenitis suppurativa. Br J Dermatol 170 (2014), 884–889.
    • (2014) Br J Dermatol , vol.170 , pp. 884-889
    • Vinding, G.R.1    Miller, I.M.2    Zarchi, K.3    Ibler, K.S.4    Ellervik, C.5    Jemec, G.B.6
  • 42
    • 77954173269 scopus 로고    scopus 로고
    • Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis
    • von Laffert, M., Helmbold, P., Wohlrab, J., Fiedler, E., Stadie, V., Marsch, W.C., Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis. Exp Dermatol 19 (2010), 533–537.
    • (2010) Exp Dermatol , vol.19 , pp. 533-537
    • von Laffert, M.1    Helmbold, P.2    Wohlrab, J.3    Fiedler, E.4    Stadie, V.5    Marsch, W.C.6
  • 43
    • 79551494835 scopus 로고    scopus 로고
    • Hidradenitis suppurativa/acne inversa: bilocated epithelial hyperplasia with very different sequelae
    • von Laffert, M., Stadie, V., Wohlrab, J., Marsch, W.C., Hidradenitis suppurativa/acne inversa: bilocated epithelial hyperplasia with very different sequelae. Br J Dermatol 164 (2011), 367–371.
    • (2011) Br J Dermatol , vol.164 , pp. 367-371
    • von Laffert, M.1    Stadie, V.2    Wohlrab, J.3    Marsch, W.C.4
  • 44
    • 78449287185 scopus 로고    scopus 로고
    • Gamma-secretase gene mutations in familial acne inversa
    • Wang, B., Yang, W., Wen, W., Sun, J., Su, B., Liu, B., et al. Gamma-secretase gene mutations in familial acne inversa. Science, 330, 2010, 1065.
    • (2010) Science , vol.330 , pp. 1065
    • Wang, B.1    Yang, W.2    Wen, W.3    Sun, J.4    Su, B.5    Liu, B.6
  • 45
    • 84876276795 scopus 로고    scopus 로고
    • Myeloid marker S100A8/A9 and lymphocyte marker, soluble interleukin 2 receptor: biomarkers of hidradenitis suppurativa disease activity?
    • Wieland, C.W., Vogl, T., Ordelman, A., Vloedgraven, H.G., Verwoolde, L.H., Rensen, J.M., et al. Myeloid marker S100A8/A9 and lymphocyte marker, soluble interleukin 2 receptor: biomarkers of hidradenitis suppurativa disease activity?. Br J Dermatol 168 (2013), 1252–1258.
    • (2013) Br J Dermatol , vol.168 , pp. 1252-1258
    • Wieland, C.W.1    Vogl, T.2    Ordelman, A.3    Vloedgraven, H.G.4    Verwoolde, L.H.5    Rensen, J.M.6
  • 46
    • 79251585577 scopus 로고    scopus 로고
    • Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa
    • Wolk, K., Warszawska, K., Hoeflich, C., Witte, E., Schneider-Burrus, S., Witte, K., et al. Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa. J Immunol 186 (2011), 1228–1239.
    • (2011) J Immunol , vol.186 , pp. 1228-1239
    • Wolk, K.1    Warszawska, K.2    Hoeflich, C.3    Witte, E.4    Schneider-Burrus, S.5    Witte, K.6
  • 47
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • Wright, G.W., Simon, R.M., A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 19 (2003), 2448–2455.
    • (2003) Bioinformatics , vol.19 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 48
    • 79951516747 scopus 로고    scopus 로고
    • TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes
    • Yamasaki, K., Kanada, K., Macleod, D.T., Borkowski, A.W., Morizane, S., Nakatsuji, T., et al. TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol 131 (2011), 688–697.
    • (2011) J Invest Dermatol , vol.131 , pp. 688-697
    • Yamasaki, K.1    Kanada, K.2    Macleod, D.T.3    Borkowski, A.W.4    Morizane, S.5    Nakatsuji, T.6
  • 49
    • 0025367937 scopus 로고
    • Hidradenitis suppurativa: a disease of follicular epithelium, rather than apocrine glands
    • Yu, C.C., Cook, M.G., Hidradenitis suppurativa: a disease of follicular epithelium, rather than apocrine glands. Br J Dermatol 122 (1990), 763–769.
    • (1990) Br J Dermatol , vol.122 , pp. 763-769
    • Yu, C.C.1    Cook, M.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.