Gene induction pathways mediated by distinct IRFs during viral infection

Biochemical and Biophysical Research Communications

Volumn 283, Issue 5, 2001, Pages 1150-1156

  Nakaya, Takeo ^a   Sato, Mitsuharu ^a   Hata, Naoki ^a   Asagiri, Masataka ^a   Suemori, Hirofumi ^b   Noguchi, Shigeru ^b   Tanaka, Nobuyuki ^a   Taniguchi, Tadatsugu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Anti viral response; Cytokines; DRAF1; IFN inducible genes; Interferons; IRF 3; IRF 7; ISGF3; ISRE; Transcriptional regulation

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE DISRUPTION; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; VIRUS INFECTION;

EID: 0034801322     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4913     Document Type: Article

References (50)

1. Interferons and other cytokines
2. Transcriptional activation: A complex puzzle with few easy pieces
3. Biochemistry of interferons and their actions
4. The interferon genes
5. Interferons and their actions
6. Genetic control of host resistance to infection
7. IRF family of transcription factors as regulators of host defense
8. The growing family of interferon regulatory factors
9. Interferon regulatory factors: The next generation
10. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
11. ISGF3γ/p48, a specificity switch for interferon activated transcription factors
12. A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus
13. Two different virus-inducible elements are required for human β-interferon gene regulation
14. Upstream regulatory elements of murine α4-interferon gene conconfer inducibility and cell type-restricted expression
15. Synergism between distinct enhanson domains in viral induction of the human β interferon gene
16. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements
17. Characterization of specific DNA-binding factors activated by double-stranded RNA as positive regulators of interferon α/β-stimulated genes
18. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1
19. Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3
20. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
21. Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-β gene
22. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
23. Direct triggering of the type I interferon system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/p300
24. Differential viral induction of distinct interferon-a genes by positive feedback through interferon regulatory factor-7
25. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
26. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes
27. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction
28. Regulation of IFN-α/β genes: Evidence for a dual function of the transcription factor complex ISGF3 in the production and action of IFN-α/β
29. Essential and non-redundant roles of p48 (ISGF3γ) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies
30. + T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-α/β signaling
31. The glucocorticoid attenuated response genes GARG-16 and GARG-39, and GARG-49/IRG2 encode inducible proteins containing multiple tetratricopeptide repeat domains
32. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element
33. Structure of two forms of the interferon-induced (2′-5′) oligo A synthetase of human cells based on cDNAs and gene sequences
34. Enhancer-like interferon responsive sequences of the human and murine (2′-5′) oligoadenylate synthetase gene promoters
35. Complementation of a mutant cell line: Central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways
36. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
37. Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons
38. Interferon-stimulated transcription: Isolation of an inducible gene and identification of its regulatory region
39. Cooperative interaction between interferon (IFN) stimulus response element and κB sequence motifs controls IFN-γ and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter
40. Mechanism of interferon action: Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase
41. Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine
42. Immunoregulatory properties of ISG15, an interferon-induced cytokine
43. Viral subversion of the immune system
44. Viral mechanisms of immune evasion
45. Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
46. Virus interception of cytokine-regulated pathways
47. Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon and silencing by hypermethylation
48. Silencer activity in the interferon-A gene promoters
49. Synergism between multiple virus-induced factor-binding elements involved in the differential expression of interferon A genes