Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

Hepatology

Volumn 64, Issue 6, 2016, Pages 1994-2014

  Tanaka, Satoshi ^a   Hikita, Hayato ^a   Tatsumi, Tomohide ^a   Sakamori, Ryotaro ^a   Nozaki, Yasutoshi ^a   Sakane, Sadatsugu ^a   Shiode, Yuto ^a   Nakabori, Tasuku ^a   Saito, Yoshinobu ^a   Hiramatsu, Naoki ^a   Tabata, Keisuke ^a   Kawabata, Tsuyoshi ^a   Hamasaki, Maho ^a   Eguchi, Hidetoshi ^a   Nagano, Hiroaki ^a   Yoshimori, Tamotsu ^a   Takehara, Tetsuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PALMITIC ACID; REGULATOR PROTEIN; RUBICON; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; RUBICON PROTEIN, MOUSE; SIGNAL PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL MATURATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPID DIET; LIPID STORAGE; LIVER CELL; MALE; MOLECULAR PATHOLOGY; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; KNOCKOUT MOUSE; LIPID METABOLISM; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PHYSIOLOGY; TIME FACTOR;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELLS, CULTURED; HEPATOCYTES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NON-ALCOHOLIC FATTY LIVER DISEASE; TIME FACTORS; UP-REGULATION;

EID: 84992426207     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28820     Document Type: Article

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