-
1
-
-
84975795680
-
An integrated map of genetic variation from 1, 092 human genomes
-
1000 Genomes Project Consortium
-
1000 Genomes Project Consortium. (2012) An integrated map of genetic variation from 1,092 human genomes. Nature, 491, 56-65.
-
(2012)
Nature
, vol.491
, pp. 56-65
-
-
-
2
-
-
79851468862
-
Synthetic associations are unlikely to account for many common disease genome-wide association signals
-
Anderson, C.A. et al. (2011) Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol., 9, e1000580.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1000580
-
-
Anderson, C.A.1
-
3
-
-
77953233453
-
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
-
Atwell, S. et al. (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature, 465, 627-631.
-
(2010)
Nature
, vol.465
, pp. 627-631
-
-
Atwell, S.1
-
4
-
-
3042653185
-
Maximum-likelihood estimation of haplotype frequencies in nuclear families
-
Becker, T. and Knapp, M. (2004) Maximum-likelihood estimation of haplotype frequencies in nuclear families. Genet. Epidemiol., 27, 21-32.
-
(2004)
Genet. Epidemiol.
, vol.27
, pp. 21-32
-
-
Becker, T.1
Knapp, M.2
-
6
-
-
84872040426
-
Chapter 11: Genome-wide association studies
-
Bush, W.S. and Moore, J.H. (2012) Chapter 11: genome-wide association studies. PLoS Comput. Biol., 8, e1002822.
-
(2012)
PLoS Comput. Biol.
, vol.8
, pp. e1002822
-
-
Bush, W.S.1
Moore, J.H.2
-
7
-
-
84864579680
-
Predicting signatures of "synthetic associations" and "natural associations" from empirical patterns of human genetic variation
-
Chang, D. and Keinan, A. (2012) Predicting signatures of "synthetic associations" and "natural associations" from empirical patterns of human genetic variation. PLoS Comput. Biol., 8, e1002600.
-
(2012)
PLoS Comput. Biol.
, vol.8
, pp. e1002600
-
-
Chang, D.1
Keinan, A.2
-
8
-
-
84930213392
-
Second-generation PLINK: Rising to the challenge of larger and richer datasets
-
Chang, C.C. et al. (2015) Second-generation PLINK: rising to the challenge of larger and richer datasets. GigaScience, 4, 7.
-
(2015)
GigaScience
, vol.4
, pp. 7
-
-
Chang, C.C.1
-
9
-
-
84871952176
-
Improved whole-chromosome phasing for disease and population genetic studies
-
Deleneau, S.P. et al. (2013) Improved whole-chromosome phasing for disease and population genetic studies. Nat. Methods, 10, 5-6.
-
(2013)
Nat. Methods
, vol.10
, pp. 5-6
-
-
Deleneau, S.P.1
-
10
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
Dickson, S.P. et al. (2010) Rare variants create synthetic genome-wide associations. PLoS Biol., 8, e1000294.
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000294
-
-
Dickson, S.P.1
-
11
-
-
84938964578
-
Windfalls and pitfalls: Applications of population genetics to the search for disease genes
-
Edge, M.D. et al. (2013) Windfalls and pitfalls: applications of population genetics to the search for disease genes. Evol. Med. Public Health, 254-272.
-
(2013)
Evol. Med. Public Health
, pp. 254-272
-
-
Edge, M.D.1
-
12
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier, L. and Slatkin, M. (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol., 12, 921-927.
-
(1995)
Mol. Biol. Evol.
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
13
-
-
77949773445
-
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
-
Fellay, J. et al. (2010) ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature, 464, 405-408.
-
(2010)
Nature
, vol.464
, pp. 405-408
-
-
Fellay, J.1
-
14
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's Disease susceptibility loci
-
Franke, A. et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's Disease susceptibility loci. Nat. Genet., 42, 1118-1125.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
-
15
-
-
65949107547
-
Common genetic variation and human traits
-
1696-1608
-
Goldstein, D.B. (2009) Common genetic variation and human traits. N. Engl. J. Med., 360, 1696-1608.
-
(2009)
N. Engl. J. Med.
, vol.360
-
-
Goldstein, D.B.1
-
16
-
-
79851487366
-
The importance of synthetic associations will only be resolved empirically
-
Goldstein, D.B. (2011) The importance of synthetic associations will only be resolved empirically. PLoS Biol., 9, e1001008.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1001008
-
-
Goldstein, D.B.1
-
17
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
Hirschhorn, J.N. and Daly, M.J. (2005) Genome-wide association studies for common diseases and complex traits. Nat. Rev. Genet., 6, 95-108.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
18
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins, L. et al. (2012) Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature, 1, 119-124.
-
(2012)
Nature
, vol.1
, pp. 119-124
-
-
Jostins, L.1
-
19
-
-
84879221281
-
Genome-wide association study signal at the 12q12 locus for Crohn's Disease may represent associations with the MUC19 gene
-
Kumar, V. et al. (2013) Genome-wide association study signal at the 12q12 locus for Crohn's Disease may represent associations with the MUC19 gene. Inflamm. Bowel Dis., 19, 1254-1259.
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 1254-1259
-
-
Kumar, V.1
-
20
-
-
33344470090
-
PopGen: Population based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships
-
Krawczak, M. et al. (2006) PopGen: population based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships. Commun. Genet., 9, 55-61.
-
(2006)
Commun. Genet.
, vol.9
, pp. 55-61
-
-
Krawczak, M.1
-
21
-
-
0028913523
-
An E-M algorithm and testing strategy for multiplelocus haplotypes
-
Long, J.C. et al. (1995) An E-M algorithm and testing strategy for multiplelocus haplotypes. Am. J. Hum. Genet., 56, 799-810.
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 799-810
-
-
Long, J.C.1
-
22
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type2 diabetes susceptibility
-
Mahajan, A. et al. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type2 diabetes susceptibility. Nat. Genet., 46, 234-244.
-
(2014)
Nat. Genet.
, vol.46
, pp. 234-244
-
-
Mahajan, A.1
-
23
-
-
84855853297
-
Molecular genetic studies of complex phenotypes
-
Marian, A.J. (2012) Molecular genetic studies of complex phenotypes. Transl. Res., 159, 64-79.
-
(2012)
Transl. Res.
, vol.159
, pp. 64-79
-
-
Marian, A.J.1
-
24
-
-
84991502822
-
A reference panel of 64,976 haplotypes for genotype imputation
-
McCarthy, S. (2015) A reference panel of 64,976 haplotypes for genotype imputation. BioRXiv: Preprint Server Biol., 1-24.
-
(2015)
BioRXiv: Preprint Server Biol.
, pp. 1-24
-
-
McCarthy, S.1
-
25
-
-
78149436551
-
Synthetic associations in the context of genome-wide association scan signals
-
Orozco, G. et al. (2010) Synthetic associations in the context of genome-wide association scan signals. Hum. Mol. Genet., 19, R137-R144.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. R137-R144
-
-
Orozco, G.1
-
26
-
-
78951470427
-
Conditions under which genome-wide association studies will be positively misleading
-
Platt, A. et al. (2010) Conditions under which genome-wide association studies will be positively misleading. Genetics, 186, 1045-1052.
-
(2010)
Genetics
, vol.186
, pp. 1045-1052
-
-
Platt, A.1
-
27
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet., 81, 559-575.
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
28
-
-
78649502323
-
Investigation of a genome wide association signal for obesity: Synthetic association and haplotype analyses at the melanocortin 4 receptor gene locus
-
Scherag, A. et al. (2010) Investigation of a genome wide association signal for obesity: synthetic association and haplotype analyses at the melanocortin 4 receptor gene locus. PLoS One, 5, e13967.
-
(2010)
PLoS One
, vol.5
, pp. e13967
-
-
Scherag, A.1
-
29
-
-
63449117825
-
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose
-
Takeuchi, F. et al. (2009) A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet., 5, e1000433.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000433
-
-
Takeuchi, F.1
-
30
-
-
79959870865
-
Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants
-
Takeuchi, F. et al. (2011) Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. Genome Res., 21, 1122-1130.
-
(2011)
Genome Res.
, vol.21
, pp. 1122-1130
-
-
Takeuchi, F.1
-
31
-
-
33947227273
-
Association of warfarin dose with genes involved in its action and metabolism
-
Wadelius, M. et al. (2007) Association of warfarin dose with genes involved in its action and metabolism. Hum. Genet., 121, 23-34.
-
(2007)
Hum. Genet.
, vol.121
, pp. 23-34
-
-
Wadelius, M.1
-
32
-
-
77951974619
-
Interpretation of association signals and identification of causal variants from genome-wide association studies
-
Wang, K. et al. (2010) Interpretation of association signals and identification of causal variants from genome-wide association studies. Am. J. Hum. Genet., 86, 730-742.
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 730-742
-
-
Wang, K.1
-
33
-
-
79851487367
-
Synthetic associations created by rare variants do not explain mostGWAS results
-
Wray, N.R. et al. (2011) Synthetic associations created by rare variants do not explain mostGWAS results. PLoS Biol., 9, e1000579.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1000579
-
-
Wray, N.R.1
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