Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines

Nature Chemistry

Volumn 8, Issue 11, 2016, Pages 1076-1082

  Pavlidis, Ioannis V ^a,b   Weiß, Martin S ^a   Genz, Maika ^a   Spurr, Paul ^c   Hanlon, Steven P ^c   Wirz, Beat ^c   Iding, Hans ^c   Bornscheuer, Uwe T ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF KASSEL   (Germany)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AMINOTRANSFERASE; QUINONE DERIVATIVE;

BINDING SITE; BIOCATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENETICS; KINETICS; METABOLISM; PROTEIN ENGINEERING; SITE DIRECTED MUTAGENESIS; STEREOISOMERISM;

AMINES; BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; QUINONES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRANSAMINASES;

EID: 84992316292     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.2578     Document Type: Article

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