Monocytes/macrophages upregulate the hyaluronidase HYAL1 and adapt its subcellular trafficking to promote extracellular residency upon differentiation into osteoclasts

PLoS ONE

Volumn 11, Issue 10, 2016, Pages

  Puissant, Emeline ^a   Boonen, Marielle ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN K; COLONY STIMULATING FACTOR 1; HYALURONIC ACID; HYALURONIDASE; HYALURONIDASE HYAL1; MANNOSE RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACP5 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; CHONDROITIN SULFATE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HYAL1 PROTEIN, MOUSE; HYAL2 PROTEIN, MOUSE; HYALURONOGLUCOSAMINIDASE; LECTIN; MANNOSE BINDING LECTIN;

ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GENE EXPRESSION; HYDROLYSIS; IN VITRO STUDY; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BONE DEVELOPMENT; BONE MARROW CELL; CELL CULTURE; CYTOLOGY; DEFICIENCY; ENDOSOME; EXOCYTOSIS; GENETICS; KNOCKOUT MOUSE; LYSOSOME; METABOLISM; RAW 264.7 CELL LINE;

ANIMALS; BONE MARROW CELLS; CATHEPSIN K; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROITIN SULFATES; ENDOSOMES; EXOCYTOSIS; GPI-LINKED PROTEINS; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; LECTINS, C-TYPE; LYSOSOMES; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; MICE, KNOCKOUT; MONOCYTES; OSTEOCLASTS; OSTEOGENESIS; RANK LIGAND; RAW 264.7 CELLS; RECEPTORS, CELL SURFACE; TARTRATE-RESISTANT ACID PHOSPHATASE; UP-REGULATION;

EID: 84992315783     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0165004     Document Type: Article

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