Hyaluronidase Hyal1 increases tumor cell proliferation and motility through accelerated vesicle trafficking

Journal of Biological Chemistry

Volumn 290, Issue 21, 2015, Pages 13144-13156

  McAtee, Caitlin O ^a   Berkebile, Abigail R ^a   Elowsky, Christian G ^a   Fangman, Teresa ^a   Barycki, Joseph J ^a   Wahl, James K ^b   Khalimonchuk, Oleh ^a   Naslavsky, Naava ^c   Caplan, Steve ^c,d   Simpson, Melanie A ^a,d  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CELL PROLIFERATION; CELLS; DISEASES; ENZYME ACTIVITY; HYALURONIC ACID; MOLECULAR BIOLOGY; PHYSIOLOGY; PROTEINS; RECYCLING; TUMORS;

CONSTITUTIVELY ACTIVES; ENDOCYTIC RECYCLING; ENDOPLASMIC RETICULUM; ENZYMATIC ACTIVITIES; EXPRESSION CONSTRUCTS; EXTRACELLULAR SPACE; SUBCELLULAR DISTRIBUTION; VESICULAR TRAFFICKING;

CYTOLOGY;

HYALURONIDASE; HYALURONIDASE 1; RAB PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG; HISTONE ACETYLTRANSFERASE; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; MGEA5 PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTICLE; CANCER CELL LINE; CATALYSIS; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENDOSOME; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME RELEASE; HUMAN; HUMAN CELL; INTERNALIZATION; LYSOSOME; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUCROSE DENSITY GRADIENT CENTRIFUGATION; ADENOCARCINOMA; APOPTOSIS; CELL FRACTIONATION; CELL MOTION; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; PROTEIN TRANSPORT; TRANSPORT VESICLE; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADENOCARCINOMA; ANTIGENS, NEOPLASM; APOPTOSIS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; ENDOCYTOSIS; ENDOSOMES; HISTONE ACETYLTRANSFERASES; HUMANS; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; MALE; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; SUBCELLULAR FRACTIONS; TRANSFERRIN; TRANSPORT VESICLES; TUMOR CELLS, CULTURED;

EID: 84930000039     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.647446     Document Type: Article

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