Sex-dependent alterations of Ca21 cycling in human cardiac hypertrophy and heart failure

Europace

Volumn 18, Issue 9, 2016, Pages 1440-1448

  Fischer, Thomas H ^a   Herting, Jonas ^a   Eiringhaus, Jörg ^a   Pabel, Steffen ^a   Hartmann, Nico H ^a   Ellenberger, David ^a   Friedrich, Martin ^a   Renner, André ^b   Gummert, Jan ^b   Maier, Lars S ^c   Zabel, Markus ^a,d   Hasenfuss, Gerd ^a,d   Sossalla, Samuel ^a,d  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Arrhythmias; Calcium cycling; Heart failure; Sex gender; SR calcium leak

Indexed keywords

CALCIUM;

AGED; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARDIAC MUSCLE CELL; CELL ISOLATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EPIFLUORESCENCE MICROSCOPY; FEMALE; HEART AFTERLOAD; HEART ARRHYTHMIA; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SEX DIFFERENCE; ADULT; ARRHYTHMIAS, CARDIAC; CARDIOMEGALY; COMPLICATION; FLUORESCENCE MICROSCOPY; HEART CONTRACTION; HEART RATE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; TIME FACTOR;

ADULT; AGED; ARRHYTHMIAS, CARDIAC; CALCIUM SIGNALING; CARDIOMEGALY; FEMALE; HEART FAILURE; HEART RATE; HUMANS; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; SARCOPLASMIC RETICULUM; SEX FACTORS; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 84992199658     PISSN: 10995129     EISSN: 15322092     Source Type: Journal    
DOI: 10.1093/europace/euv313     Document Type: Article

References (26)

1. Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 2005;352:225-37.
2. Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA III, Freedman RA, Gettes LS et al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. Circulation 2008;117:e350-408.
3. MacFadden DR, Crystal E, Krahn AD, Mangat I, Healey JS, Dorian P et al. Sex differences in implantable cardioverter-defibrillator outcomes: findings from a prospective defibrillator database. Ann Intern Med 2012;156:195-203.
4. Kannel WB, Wilson PW, D'Agostino RB, Cobb J. Sudden coronary death in women. Am Heart J 1998;136:205-12.
5. Wigginton JG, Pepe PE, Bedolla JP, DeTamble LA, Atkins JM. Sex-related differences in the presentation and outcome of out-of-hospital cardiopulmonary arrest: A multiyear, prospective, population-based study. Crit Care Med 2002;30(4 Suppl): S131-6.
6. de Simone G, Devereux RB, Roman MJ, Ganau A, Chien S, Alderman MH et al. Gender differences in left ventricular anatomy, blood viscosity and volume regulatory hormones in normal adults. Am J Cardiol 1991;68:1704-8.
7. Gowd BM, Thompson PD. Effect of female sex on cardiac arrhythmias. Cardiol Rev 2012;20:297-303.
8. Farrell SR, Ross JL, Howlett SE. Sex differences in mechanisms of cardiac excitationcontraction coupling in rat ventricular myocytes. Am J Physiol Heart Circ Physiol 2010; 299:H36-45.
9. Fischer TH, Herting J, Tirilomis T, Renner A, Neef S, Toischer K et al. Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology. Circulation 2013;128: 970-81.
10. Sossalla S, Fluschnik N, Schotola H, Ort KR, Neef S, Schulte T et al. Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Circ Res 2010;107:1150-61.
11. Xu L, Eu JP, Meissner G, Stamler JS. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 1998;279:234-7.
12. Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res 1998;37:279-89.
13. Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K et al. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circ Heart Fail 2009;2:664-75.
14. Picht E, Zima AV, Blatter LA, Bers DM. SparkMaster: automated calcium spark analysis with ImageJ. Am J Physiol Cell Physiol 2007;293:C1073-81.
15. Ghanbari H, Dalloul G, Hasan R, Daccarett M, Saba S, David S et al. Effectiveness of implantable cardioverter-defibrillators for the primary prevention of sudden cardiac death in women with advanced heart failure: A meta-analysis of randomized controlled trials. Arch Intern Med 2009;169:1500-6.
16. Chen J, Petranka J, Yamamura K, London RE, Steenbergen C, Murphy E. Gender differences in sarcoplasmic reticulum calcium loading after isoproterenol. Am J Physiol Heart Circ Physiol 2003;285:H2657-62.
17. Petre RE, Quaile MP, Rossman EI, Ratcliffe SJ, Bailey BA, Houser SR et al. Sex-based differences in myocardial contractile reserve. Am J Physiol Regul Integr Comp Physiol 2007;292:R810-8.
18. Fares E, Pyle WG, Ray G, Rose RA, Denovan-Wright EM, Chen RP et al. The impact of ovariectomy on calcium homeostasis and myofilament calcium sensitivity in the aging mouse heart. PLoS ONE 2013;8:e74719.
19. Curl CL, Wendt IR, Kotsanas G. Effects of gender on intracellular. Pflugers Arch 2001;441:709-16.
20. Vizgirda VM,Wahler GM, Sondgeroth KL, Ziolo MT, SchwertzDW. Mechanisms of sex differences in rat cardiac myocyte response to beta-adrenergic stimulation. Am J Physiol Heart Circ Physiol 2002;282:H256-63.
21. Grandy SA, Howlett SE. Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice. Am J Physiol Heart Circ Physiol 2006;291:H2362-70.
22. SchwertzDW, Beck JM, Kowalski JM, Ross JD. Sex differences in the response of rat heart ventricle to calcium. Biol Res Nurs 2004;5:286-98.
23. Davia K, Bernobich E, Ranu HK, del Monte F, Terracciano CM, MacLeod KT et al. SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes. J Mol Cell Cardiol 2001;33:1005-15.
24. Bai Y, Jones PP, Guo J, Zhong X, Clark RB, Zhou Q et al. Phospholamban knockout breaks arrhythmogenic Ca(2)(+) waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circ Res 2013;113:517-26.
25. Myles RC, Wang L, Bers DM, Ripplinger CM. Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart. J Physiol 2015;593:1479-93.
26. Meyer R, Linz KW, Surges R, Meinardus S, Vees J, Hoffmann A et al. Rapid modulation of L-type calcium current by acutely applied oestrogens in isolated cardiac myocytes from human, guinea-pig and rat. Exp Physiol 1998;83:305-21.