Ca2+/calmodulin-dependent protein kinase ii and protein kinase a differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology

Circulation

Volumn 128, Issue 9, 2013, Pages 970-981

  Fischer, Thomas H ^a   Herting, Jonas ^a   Tirilomis, Theodor ^a   Renner, André ^b   Neef, Stefan ^a   Toischer, Karl ^a   Ellenberger, David ^a   Förster, Anna ^a   Schmitto, Jan D ^c   Gummert, Jan ^b   Schöndube, Friedrich A ^a   Hasenfuss, Gerd ^a,d   Maier, Lars S ^a   Sossalla, Samuel ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Calcium calmodulin dependent protein kinase type 2; Heart failure; Hypertrophy; Protein kinases; Sarcoplasmic reticulum

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; RYANODINE RECEPTOR 2; CALCIUM; ENZYME INHIBITOR; PROTEIN KINASE; RYANODINE RECEPTOR;

AGED; ARTICLE; CALCIUM DEPLETION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART FAILURE; HEART MUSCLE; HEART VENTRICLE HYPERTROPHY; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; CARDIOMEGALY; CASE CONTROL STUDY; COMPARATIVE STUDY; DISEASE COURSE; DRUG ANTAGONISM; DRUG EFFECT; HOMEOSTASIS; HYPERTROPHY; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION;

CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; HEART FAILURE; HYPERTROPHY; PROTEIN KINASES; SARCOPLASMIC RETICULUM;

AGED; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMEGALY; CASE-CONTROL STUDIES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE PROGRESSION; ENZYME INHIBITORS; FEMALE; HEART FAILURE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 84883206388     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.001746     Document Type: Article

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