메뉴 건너뛰기




Volumn 1, Issue , 2015, Pages

Activin-a signaling promotes epithelial–mesenchymal transition, invasion, and metastatic growth of breast cancer

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84992039419     PISSN: None     EISSN: 23744677     Source Type: Journal    
DOI: 10.1038/npjbcancer.2015.7     Document Type: Article
Times cited : (60)

References (45)
  • 1
    • 84876817355 scopus 로고    scopus 로고
    • Beyond TGFβ: Roles of other TGFβ superfamily members in cancer
    • Wakefield LM, Hill CS. Beyond TGFβ: roles of other TGFβ superfamily members in cancer. Nat Rev Cancer 2013; 13: 328–341.
    • (2013) Nat Rev Cancer , vol.13 , pp. 328-341
    • Wakefield, L.M.1    Hill, C.S.2
  • 2
    • 0023632768 scopus 로고
    • Studies of the inhibin family of hormones: A review
    • Rivier C, Vale W, Rivier J. Studies of the inhibin family of hormones: a review. Horm Res 1987; 28: 104–118.
    • (1987) Horm Res , vol.28 , pp. 104-118
    • Rivier, C.1    Vale, W.2    Rivier, J.3
  • 3
    • 42049114841 scopus 로고    scopus 로고
    • Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer
    • Tsuchida K, Nakatani M, Uezumi A, Murakami T, Cui X. Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer. Endocr J 2008; 55: 11–21.
    • (2008) Endocr J , vol.55 , pp. 11-21
    • Tsuchida, K.1    Nakatani, M.2    Uezumi, A.3    Murakami, T.4    Cui, X.5
  • 4
    • 0022470831 scopus 로고
    • Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin
    • Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M et al. Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin. Nature 1986; 321: 779–782.
    • (1986) Nature , vol.321 , pp. 779-782
    • Ling, N.1    Ying, S.Y.2    Ueno, N.3    Shimasaki, S.4    Esch, F.5    Hotta, M.6
  • 5
    • 0022907945 scopus 로고
    • Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid
    • Vale W, Rivier J, Vaughan J, McClintock R, Corrigan A, Woo W et al. Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 1986; 321: 776–779.
    • (1986) Nature , vol.321 , pp. 776-779
    • Vale, W.1    Rivier, J.2    Vaughan, J.3    McClintock, R.4    Corrigan, A.5    Woo, W.6
  • 7
    • 0024286302 scopus 로고
    • A novel action of activin A: Stimulation of insulin secretion in rat pancreatic islets
    • Totsuka Y, Tabuchi M, Kojima I, Shibai H, Ogata E. A novel action of activin A: stimulation of insulin secretion in rat pancreatic islets. Biochem Biophys Res Commun 1988; 156: 335–339.
    • (1988) Biochem Biophys Res Commun , vol.156 , pp. 335-339
    • Totsuka, Y.1    Tabuchi, M.2    Kojima, I.3    Shibai, H.4    Ogata, E.5
  • 11
    • 16444373230 scopus 로고    scopus 로고
    • Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
    • Beattie GM, Lopez AD, Bucay N, Hinton A, Firpo MT, King CC et al. Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells 2005; 23: 489–495.
    • (2005) Stem Cells , vol.23 , pp. 489-495
    • Beattie, G.M.1    Lopez, A.D.2    Bucay, N.3    Hinton, A.4    Firpo, M.T.5    King, C.C.6
  • 12
    • 41949098657 scopus 로고    scopus 로고
    • Activin-A: A novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production
    • Robson NC, Phillips DJ, McAlpine T, Shin A, Svobodova S, Toy T et al. Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production. Blood 2008; 111: 2733–2743.
    • (2008) Blood , vol.111 , pp. 2733-2743
    • Robson, N.C.1    Phillips, D.J.2    McAlpine, T.3    Shin, A.4    Svobodova, S.5    Toy, T.6
  • 13
    • 70349086989 scopus 로고    scopus 로고
    • Activin a enhances prostate cancer cell migration through activation of androgen receptor and is overexpressed in metastatic prostate cancer
    • Kang H-Y, Huang H-Y, Hsieh C-Y, Li C-F, Shyr C-R, Tsai M-Y et al. Activin a enhances prostate cancer cell migration through activation of androgen receptor and is overexpressed in metastatic prostate cancer. J Bone Min Res 2009; 24: 1180–1193.
    • (2009) J Bone Min Res , vol.24 , pp. 1180-1193
    • Kang, H.-Y.1    Huang, H.-Y.2    Hsieh, C.-Y.3    Li, C.-F.4    Shyr, C.-R.5    Tsai, M.-Y.6
  • 15
    • 65549129119 scopus 로고    scopus 로고
    • Upregulated INHBA expression may promote cell proliferation and is associated with poor survival in lung adenocarcinoma1
    • Seder CW, Hartojo W, Lin L, Silvers AL, Wang Z, Thomas DG et al. Upregulated INHBA expression may promote cell proliferation and is associated with poor survival in lung adenocarcinoma1. Neoplasia 2009; 11: 388–396.
    • (2009) Neoplasia , vol.11 , pp. 388-396
    • Seder, C.W.1    Hartojo, W.2    Lin, L.3    Silvers, A.L.4    Wang, Z.5    Thomas, D.G.6
  • 17
    • 80755141299 scopus 로고    scopus 로고
    • Nodal/activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy
    • Lonardo E, Hermann PC, Mueller M-T, Huber S, Balic A, Miranda-Lorenzo I et al. Nodal/activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. Cell Stem Cell 2011; 9: 433–446.
    • (2011) Cell Stem Cell , vol.9 , pp. 433-446
    • Lonardo, E.1    Hermann, P.C.2    Mueller, M.-T.3    Huber, S.4    Balic, A.5    Miranda-Lorenzo, I.6
  • 18
    • 38049152697 scopus 로고    scopus 로고
    • Activin a causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells
    • Yoshinaga K, Yamashita K, Mimori K, Tanaka F, Inoue H, Mori M. Activin a causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells. Ann Surg Oncol 2008; 15: 96–103.
    • (2008) Ann Surg Oncol , vol.15 , pp. 96-103
    • Yoshinaga, K.1    Yamashita, K.2    Mimori, K.3    Tanaka, F.4    Inoue, H.5    Mori, M.6
  • 19
    • 84455174729 scopus 로고    scopus 로고
    • Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response
    • Antsiferova M, Huber M, Meyer M, Piwko-Czuchra A, Ramadan T, MacLeod AS et al. Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response. Nat Commun 2011; 2: 576.
    • (2011) Nat Commun , vol.2 , pp. 576
    • Antsiferova, M.1    Huber, M.2    Meyer, M.3    Piwko-Czuchra, A.4    Ramadan, T.5    Macleod, A.S.6
  • 21
    • 77955642517 scopus 로고    scopus 로고
    • Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival
    • Zhou X, Wang JL, Lu J, Song Y, Kwak KS, Jiao Q et al. Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell 2010; 142: 531–543.
    • (2010) Cell , vol.142 , pp. 531-543
    • Zhou, X.1    Wang, J.L.2    Lu, J.3    Song, Y.4    Kwak, K.S.5    Jiao, Q.6
  • 23
    • 0038756352 scopus 로고    scopus 로고
    • Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer
    • Jeruss JS, Sturgis CD, Rademaker AW, Woodruff TK. Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer. Cancer Res 2003; 63: 3783–3790.
    • (2003) Cancer Res , vol.63 , pp. 3783-3790
    • Jeruss, J.S.1    Sturgis, C.D.2    Rademaker, A.W.3    Woodruff, T.K.4
  • 25
    • 0030663881 scopus 로고    scopus 로고
    • Cellular interpretation of multiple TGF-beta signals: Intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads
    • Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R et al. Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads. Development 1997; 124: 4467–4480.
    • (1997) Development , vol.124 , pp. 4467-4480
    • Candia, A.F.1    Watabe, T.2    Hawley, S.H.3    Onichtchouk, D.4    Zhang, Y.5    Derynck, R.6
  • 26
    • 84868119538 scopus 로고    scopus 로고
    • Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva
    • Luo Y-J, Su Y-H. Opposing nodal and BMP signals regulate left-right asymmetry in the sea urchin larva. PLoS Biol 2012; 10: e1001402.
    • (2012) Plos Biol , vol.10
    • Luo, Y.-J.1    Su, Y.-H.2
  • 27
    • 22244492306 scopus 로고    scopus 로고
    • Carcinoma invasion and metastasis: A role for epithelial-mesenchymal transition?
    • Thompson EW, Newgreen DF. Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Res 2005; 65: 5991–5995.
    • (2005) Cancer Res , vol.65 , pp. 5991-5995
    • Thompson, E.W.1    Newgreen, D.F.2
  • 28
    • 35348854478 scopus 로고    scopus 로고
    • Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice
    • Lu S, Lee J, Revelo M, Wang X, Dong Z. Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice. Clin Cancer Res 2007; 13: 5692–5702.
    • (2007) Clin Cancer Res , vol.13 , pp. 5692-5702
    • Lu, S.1    Lee, J.2    Revelo, M.3    Wang, X.4    Dong, Z.5
  • 29
    • 76249084838 scopus 로고    scopus 로고
    • Smad signaling is required to maintain epigenetic silencing during breast cancer progression
    • Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U et al. Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Res 2010; 70: 968–978.
    • (2010) Cancer Res , vol.70 , pp. 968-978
    • Papageorgis, P.1    Lambert, A.W.2    Ozturk, S.3    Gao, F.4    Pan, H.5    Manne, U.6
  • 30
    • 84869021181 scopus 로고    scopus 로고
    • Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation
    • Calon A, Espinet E, Palomo-Ponce S, Tauriello DVF, Iglesias M, Céspedes MV et al. Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation. Cancer Cell 2012; 22: 571–584.
    • (2012) Cancer Cell , vol.22 , pp. 571-584
    • Calon, A.1    Espinet, E.2    Palomo-Ponce, S.3    Tauriello, D.V.F.4    Iglesias, M.5    Céspedes, M.V.6
  • 32
    • 0034803035 scopus 로고    scopus 로고
    • Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation
    • Rowland-Goldsmith MA, Maruyama H, Kusama T, Ralli S, Korc M. Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation. Clin Cancer Res 2001; 7: 2931–2940.
    • (2001) Clin Cancer Res , vol.7 , pp. 2931-2940
    • Rowland-Goldsmith, M.A.1    Maruyama, H.2    Kusama, T.3    Ralli, S.4    Korc, M.5
  • 33
    • 84856528891 scopus 로고    scopus 로고
    • Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition
    • Zhang Y, Toy K a, Kleer CG. Metaplastic breast carcinomas are enriched in markers of tumor-initiating cells and epithelial to mesenchymal transition. Mod Pathol 2012; 25: 178–184.
    • (2012) Mod Pathol , vol.25 , pp. 178-184
    • Zhang, Y.1    K A, T.2    Kleer, C.G.3
  • 34
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010; 140: 62–73.
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.3    Mazzarol, G.4    Vecchi, M.5    Ronzoni, S.6
  • 35
    • 48149098004 scopus 로고    scopus 로고
    • NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
    • Xu RH, Sampsell-Barron TL, Gu F, Root S, Peck RM, Pan G et al. NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell 2008; 3: 196–206.
    • (2008) Cell Stem Cell , vol.3 , pp. 196-206
    • Xu, R.H.1    Sampsell-Barron, T.L.2    Gu, F.3    Root, S.4    Peck, R.M.5    Pan, G.6
  • 37
    • 59649093679 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 antagonizes renal interstitial fibrosis by promoting catabolism of type I transforming growth factor-beta receptors
    • Yang Y-L, Liu Y-S, Chuang L-Y, Guh J-Y, Lee T-C, Liao T-N et al. Bone morphogenetic protein-2 antagonizes renal interstitial fibrosis by promoting catabolism of type I transforming growth factor-beta receptors. Endocrinology 2009; 150: 727–740.
    • (2009) Endocrinology , vol.150 , pp. 727-740
    • Yang, Y.-L.1    Liu, Y.-S.2    Chuang, L.-Y.3    Guh, J.-Y.4    Lee, T.-C.5    Liao, T.-N.6
  • 38
    • 77950208739 scopus 로고    scopus 로고
    • BMP-7 stops TGF-β in peritoneal fibrosis
    • Phillips AO, Fraser DJ. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrol Dial Transplant 2010; 25: 1036–1038.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1036-1038
    • Phillips, A.O.1    Fraser, D.J.2
  • 39
    • 84860314217 scopus 로고    scopus 로고
    • The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation
    • Buijs JT, van der Horst G, van den Hoogen C, Cheung H, de Rooij B, Kroon J et al. The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation. Oncogene 2012; 31: 2164–2174.
    • (2012) Oncogene , vol.31 , pp. 2164-2174
    • Buijs, J.T.1    van der Horst, G.2    van den Hoogen, C.3    Cheung, H.4    de Rooij, B.5    Kroon, J.6
  • 40
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    • Curtis C, Shah SP, Chin S-F, Turashvili G, Rueda OM, Dunning MJ et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 2012; 486: 346–352.
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1    Shah, S.P.2    Chin, S.-F.3    Turashvili, G.4    Rueda, O.M.5    Dunning, M.J.6
  • 42
    • 84861695148 scopus 로고    scopus 로고
    • Insensitivity to the growth inhibitory effects of activin A: An acquired capability in prostate cancer progression
    • Ottley E, Gold E. Insensitivity to the growth inhibitory effects of activin A: an acquired capability in prostate cancer progression. Cytokine Growth Factor Rev 2012; 23: 119–125.
    • (2012) Cytokine Growth Factor Rev , vol.23 , pp. 119-125
    • Ottley, E.1    Gold, E.2
  • 43
    • 58149236744 scopus 로고    scopus 로고
    • Roles of TGFβ in metastasis
    • Padua D, Massagué J. Roles of TGFβ in metastasis. Cell Res 2009; 19: 89–102.
    • (2009) Cell Res , vol.19 , pp. 89-102
    • Padua, D.1    Massagué, J.2
  • 44
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao M-J, Eaton EN, Ayyanan A, Zhou AY et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704–715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 45
    • 80052421199 scopus 로고    scopus 로고
    • Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: A safe and effective systemic therapeutic approach for breast cancer
    • Hu Z, Gerseny H, Zhang Z, Chen Y-J, Berg A, Zhang Z et al. Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer. Mol Ther 2011; 19: 1609–1618.
    • (2011) Mol Ther , vol.19 , pp. 1609-1618
    • Hu, Z.1    Gerseny, H.2    Zhang, Z.3    Chen, Y.-J.4    Berg, A.5    Zhang, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.