Activin A expression regulates multipotency of mesenchymal progenitor cells

Stem Cell Research and Therapy

Volumn 1, Issue 2, 2010, Pages

  Djouad, Farida ^a,b   Jackson, Wesley M ^a   Bobick, Brent E ^a,c   Janjanin, Sasa ^a,d   Song, Yingjie ^a   Huang, George T J ^a,e   Tuan, Rocky S ^a,f  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b HÔPITAL SAINT ELOI   (France)

^c UNIVERSITY OF CALGARY   (Canada)

^d KBC Zagreb   (Croatia)

^e BOSTON UNIVERSITY   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ACTIVIN A; CD14 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; COLLAGEN TYPE 2; ENDOGLIN; FOLLISTATIN; LIPOPROTEIN LIPASE; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMALL INTERFERING RNA; THY 1 ANTIGEN; TRANSCRIPTION FACTOR SOX2;

ADIPOGENESIS; ANTIGEN EXPRESSION; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; MUSCLE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TONSIL CELL; TOOTH PULP; UPREGULATION;

ACTIVINS; ADIPOGENESIS; ADULT; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROGENESIS; DENTAL PULP; FOLLISTATIN; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSION; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; MUSCLES; OSTEOGENESIS; PALATINE TONSIL; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 77957083114     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt11     Document Type: Article

References (62)

1. Regenerative medicine through mesenchymal stem cells for bone and cartilage repair. Noel D Djouad F Jorgense C, Curr Opin Investig Drugs 2002 3 1000 1004 12186258 (Pubitemid 36266786)
2. Potential of bone marrow stromal cells in applications for neuro-degenerative, neuro-traumatic and muscle degenerative diseases. Dezawa M Ishikawa H Hoshino M Itokazu Y, Nabeshima Y, Curr Neuropharmacol 2005 3 257 266 10.2174/157015905774322507 18369401 (Pubitemid 41461243)
3. Mesenchymal stem cells: clinical applications and biological characterization. Barry FP Murphy JM, Int J Biochem Cell Biol 2004 36 568 584 10.1016/j.biocel.2003.11.001 15010324 (Pubitemid 38324589)
4. Multilineage potential of adult human mesenchymal stem cells. Pittenger MF Mackay AM, Beck SC Jaiswal RK, Douglas R Mosca JD, Moorman MA Simonetti DW, Craig S Marshak DR, Science 1999 284 143 147 10.1126/science.284.5411.143 10102814 (Pubitemid 29282067)
5. Mesenchymal stromal cells: biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Kolf CM Cho E Tuan RS, Arthritis Res Ther 2007 9 204 10.1186/ar2116 17316462
6. Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. Noth U Osyczka AM, Tuli R Hickok NJ, Danielson KG Tuan RS, J Orthop Res 2002 20 1060 1069 10.1016/S0736-0266(02)00018-9 12382974
7. Adipogenic differentiation of human adult stem cells from bone marrow stroma (MSCs). Sekiya I Larson BL Vuoristo JT Cui JG, Prockop DJ, J Bone Miner Res 2004 19 256 264 10.1359/JBMR.0301220 14969395
8. Multilineage cells from human adipose tissue: implications for cell-based therapies. Zuk PA Zhu M Mizuno H Huang J, Futrell JW Katz AJ, Benhaim P Lorenz HP, Hedrick MH, Tissue Eng 2001 7 211 228 10.1089/107632701300062859 11304456 (Pubitemid 32295155)
9. Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells. Djouad F Bony C, Haupl T Uze G, Lahlou N Louis-Plence P, Apparailly F Canovas F, Reme T Sany J, Jorgensen C Noel D, Arthritis Res Ther 2005 7 1304 1315 10.1186/ar1827 16277684
10. Multipotent mesenchymal stem cells from adult human synovial membrane. De Bari C Dell'Accio F, Tylzanowski P Luyten FP, Arthritis Rheum 2001 44 1928 1942 10.1002/1529-0131(200108)44:8<1928::AID-ART331>3.0.CO;2-P 11508446 (Pubitemid 32758241)
11. Isolation and characterization of neurogenic mesenchymal stem cells in human scalp tissue. Shih DT Lee DC, Chen SC Tsai RY, Huang CT Tsai CC, Shen EY Chiu WT, Stem Cells 2005 23 1012 1020 10.1634/stemcells.2004-0125 15941858 (Pubitemid 41170957)
12. Isolation and phenotypical characterization of mesenchymal stem cells from human fetal thymus. Rzhaninova AA Gornostaeva SN Goldshtein DV, Bull Exp Biol Med 2005 139 134 140 10.1007/s10517-005-0231-4 16142296
13. Stem cells in the periodontal ligament. Ivanovski S Gronthos S, Shi S Bartold PM, Oral Dis 2006 12 358 363 10.1111/j.1601-0825.2006.01253.x 16792719 (Pubitemid 43926812)
14. Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Lee OK Kuo TK, Chen WM Lee KD, Hsieh SL Chen TH, Blood 2004 103 1669 1675 10.1182/blood-2003-05-1670 14576065 (Pubitemid 38268958)
15. Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Sarugaser R Lickorish D Baksh D Hosseini MM, Davies JE, Stem Cells 2005 23 220 229 10.1634/stemcells.2004-0166 15671145 (Pubitemid 40239517)
16. Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells. Janjanin S Djouad F Shanti RM Baksh D, Gollapudi K Prgomet D, Rackwitz L Joshi AS, Tuan RS, Arthritis Res Ther 2008 10 83 10.1186/ar2459 18662393
17. Isolation of multipotent cells from human term placenta. Yen BL Huang HI, Chien CC Jui HY, Ko BS Yao M, Shun CT Yen ML, Lee MC Chen YC, Stem Cells 2005 23 3 9 10.1634/stemcells.2004-0098 15625118 (Pubitemid 40105287)
18. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. James D Levine AJ, Besser D Hemmati-Brivanlou A, Development 2005 132 1273 1282 10.1242/dev.01706 15703277
19. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Xiao L Yuan X Sharkis SJ, Stem Cells 2006 24 1476 1486 10.1634/stemcells.2005-0299 16456129 (Pubitemid 44464664)
20. Production of activin A and its roles in inflammation and hematopoiesis. Yu J Dolter KE, Cytokines Cell Mol Ther 1997 3 169 177 9426975
21. The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A. Breit S Ashman K Wilting J Rossler J, Hatzi E Fotsis T, Schweigerer L, Cancer Res 2000 60 4596 4601 10969812 (Pubitemid 32103645)
22. Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1. Eto Y Tsuji T, Takezawa M Takano S, Yokogawa Y Shibai H, Biochem Biophys Res Commun 1987 142 1095 1103 10.1016/0006-291X(87)91528-2 3470005 (Pubitemid 17021146)
23. Activin-binding protein from rat ovary is follistatin. Nakamura T Takio K, Eto Y Shibai H, Titani K Sugino H, Science 1990 247 836 838 10.1126/science.2106159 2106159
24. Rat follistatin: gonadal and extragonadal expression and evidence for alternative splicing. Michel U Albiston A Findlay JK, Biochem Biophys Res Commun 1990 173 401 407 10.1016/S0006-291X(05)81072-1 1979488
25. Detection of functional and dimeric activin A in human marrow microenvironment: implications for the modulation of erythropoiesis. Yu AW Shao LE, Frigon NL Jr Yu J, Ann N Y Acad Sci 1994 718 285 298 discussion 298-289 10.1111/j.1749-6632.1994.tb55727.x 8185235
26. Role of transforming growth factor-beta in bone remodeling. Bonewald LF Mundy GR, Clin Orthop Relat Res 1990 250 261 276 2403492 (Pubitemid 20033993)
27. Activin A increases the bone mass of grafted bone in C3H/HeJ mice. Hirotani H Ohtsuka-Isoya M Mori S Sakai R, Eto Y Echigo S, Shinoda H, Calcif Tissue Int 2002 70 330 338 10.1007/s00223-001-2037-3 12004338 (Pubitemid 36935449)
28. Bovine bone activin enhances bone morphogenetic protein-induced ectopic bone formation. Ogawa Y Schmidt DK, Nathan RM Armstrong RM, Miller KL Sawamura SJ, Ziman JM Erickson KL, de Leon ER Rosen DM, et al. J Biol Chem 1992 267 14233 14237 1629219
29. Inhibin suppresses and activin stimulates osteoblastogenesis and osteoclastogenesis in murine bone marrow cultures. Gaddy-Kurten D Coker JK Abe E Jilka RL, Manolagas SC, Endocrinology 2002 143 74 83 10.1210/en.143.1.74 11751595 (Pubitemid 34056405)
30. Functional regulation of osteoblastic cells by the interaction of activin-A with follistatin. Hashimoto M Shoda A, Inoue S Yamada R, Kondo T Sakurai T, Ueno N Muramatsu M, J Biol Chem 1992 267 4999 5004 1537876
31. Inhibitory effects of activin-A on osteoblast differentiation during cultures of fetal rat calvarial cells. Ikenoue T Jingushi S Urabe K Okazaki K, Iwamoto Y, J Cell Biochem 1999 75 206 214 10.1002/(SICI)1097-4644(19991101)75: 2<206::AID-JCB3>3.0.CO;2-T 10502293 (Pubitemid 29463489)
32. Local administration of activin promotes fracture healing in the rat fibula fracture model. Sakai R Miwa K Eto Y, Bone 1999 25 191 196 10.1016/S8756-3282(99)00152-0 10456384 (Pubitemid 29317621)
33. Changes in extracellular activin A:follistatin ratio during differentiation of a mesenchymal progenitor cell line, ROB-C26 into osteoblasts and adipocytes. Kawabata N Kamiya N Suzuki N Matsumoto M, Takagi M, Life Sci 2007 81 8 18 10.1016/j.lfs.2007.04.011 17512555 (Pubitemid 46891500)
34. Follistatin rescues the inhibitory effect of activin A on the differentiation of bovine preadipocyte. Hirai S Matsumoto H Moriya NH Kawachi H, Yano H, Domest Anim Endocrinol 2007 33 269 280 10.1016/j.domaniend.2006.06.001 16829013 (Pubitemid 47333338)
35. Activin enhances chondrogenesis of limb bud cells: stimulation of precartilaginous mesenchymal condensations and expression of NCAM. Jiang TX Yi JR, Ying SY Chuong CM, Dev Biol 1993 155 545 557 10.1006/dbio.1993.1051 7679361
36. Expression of inhibin/activin subunit messenger ribonucleic acids during rat embryogenesis. Roberts VJ Sawchenko PE Vale W, Endocrinology 1991 128 3122 3129 10.1210/endo-128-6-3122 2036981
37. Human marrow-derived mesenchymal progenitor cells: isolation, culture expansion, and analysis of differentiation. Caterson EJ Nesti LJ, Danielson KG Tuan RS, Mol Biotechnol 2002 20 245 256 10.1385/MB:20:3:245 11936255 (Pubitemid 34252636)
38. Differentiation potential of multipotent progenitor cells derived from war-traumatized muscle tissue. Nesti LJ Jackson WM, Shanti RM Koehler SM, Aragon AB Bailey JR, Sracic MK Freedman BA, Giuliani JR Tuan RS, J Bone Joint Surg Am 2008 90 2390 2398 10.2106/JBJS.H.00049 18978407
39. Mesenchymal progenitor cells derived from traumatized human muscle. Jackson WM Aragon AB Djouad F Song Y, Koehler SM Nesti LJ, Tuan RS, J Tissue Eng Regen Med 2009 3 129 138 10.1002/term.149 19170141
40. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Gronthos S Mankani M Brahim J Robey PG, Shi S, Proc Natl Acad Sci USA 2000 97 13625 13630 10.1073/pnas.240309797 11087820
41. In vitro characterization of human dental pulp cells: various isolation methods and culturing environments. Huang GT Sonoyama W, Chen J Park SH, Cell Tissue Res 2006 324 225 236 10.1007/s00441-005-0117-9 16440193
42. Glucosamine promotes chondrogenic phenotype in both chondrocytes and mesenchymal stem cells and inhibits MMP-13 expression and matrix degradation. Derfoul A Miyoshi AD, Freeman DE Tuan RS, Osteoarthritis Cartilage 2007 15 646 655 10.1016/j.joca.2007.01.014 17337215
43. Nonexpanded primary lung and bone marrow-derived mesenchymal cells promote the engraftment of umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. in 't Anker PS Noort WA, Kruisselbrink AB Scherjon SA, Beekhuizen W Willemze R, Kanhai HH Fibbe WE, Exp Hematol 2003 31 881 889 10.1016/S0301-472X(03)00202-9 14550803
44. Modulation of immune responses by mesenchymal stem cells. Fibbe WE Nauta AJ Roelofs H, Ann N Y Acad Sci 2007 1106 272 278 10.1196/annals.1392.025 17442776 (Pubitemid 47443061)
45. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Djouad F Plence P, Bony C Tropel P, Apparailly F Sany J, Noel D Jorgensen C, Blood 2003 102 3837 3844 10.1182/blood-2003-04-1193 12881305 (Pubitemid 37409409)
46. Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism. Djouad F Charbonnier LM Bouffi C Louis-Plence P, Bony C Apparailly F, Cantos C Jorgensen C, Noel D, Stem Cells 2007 25 2025 2032 10.1634/stemcells.2006-0548 17510220
47. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Masui S Nakatake Y, Toyooka Y Shimosato D, Yagi R Takahashi K, Okochi H Okuda A, Matoba R Sharov AA, Ko MS Niwa H, Nat Cell Biol 2007 9 625 635 10.1038/ncb1589 17515932 (Pubitemid 47214724)
48. How is pluripotency determined and maintained? Niwa H, Development 2007 134 635 646 10.1242/dev.02787 17215298 (Pubitemid 46437906)
49. Inhibition of vascular endothelial cell growth by activin-A. McCarthy SA Bicknell R, J Biol Chem 1993 268 23066 23071 8226823 (Pubitemid 23328013)
50. Regulation of cell proliferation, apoptosis, and carcinogenesis by activin. Chen YG Lui HM Lin SL Lee JM, Ying SY, Exp Biol Med (Maywood) 2002 227 75 87 11815670
51. Activin A induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis. Ota F Maeshima A, Yamashita S Ikeuchi H, Kaneko Y Kuroiwa T, Hiromura K Ueki K, Kojima I Nojima Y, Arthritis Rheum 2003 48 2442 2449 10.1002/art.11249 13130463 (Pubitemid 37129421)
52. Effects of activin A on proliferation and differentiation of human lung fibroblasts. Ohga E Matsuse T Teramoto S Katayama H, Nagase T Fukuchi Y, Ouchi Y, Biochem Biophys Res Commun 1996 228 391 396 10.1006/bbrc.1996.1672 8920925 (Pubitemid 26396085)
53. The activin A-follistatin system: potent regulator of human extracellular matrix mineralization. Eijken M Swagemakers S Koedam M Steenbergen C, Derkx P Uitterlinden AG, Spek, van der PJ Visser JA de Jong FH Pols HA, van Leeuwen JP, FASEB J 2007 21 2949 2960 10.1096/fj.07-8080com 17449718 (Pubitemid 47372761)
54. All for one and one for all: condensations and the initiation of skeletal development. Hall BK Miyake T, Bioessays 2000 22 138 147 10.1002/(SICI)1521- 1878(200002)22:2<138::AID-BIES5>3.0.CO;2-4 10655033 (Pubitemid 30092080)
55. Activin A induces craniofacial cartilage from undifferentiated Xenopus ectoderm in vitro. Furue M Myoishi Y, Fukui Y Ariizumi T, Okamoto T Asashima M, Proc Natl Acad Sci USA 2002 99 15474 15479 10.1073/pnas.242597399 12424341 (Pubitemid 35403958)
56. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Beyth S Borovsky Z, Mevorach D Liebergall M, Gazit Z Aslan H, Galun E Rachmilewitz J, Blood 2005 105 2214 2219 10.1182/blood-2004-07-2921 15514012 (Pubitemid 40731815)
57. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Jiang XX Zhang Y Liu B Zhang SX, Wu Y Yu XD, Mao N, Blood 2005 105 4120 4126 10.1182/blood-2004-02-0586 15692068 (Pubitemid 40656164)
58. Suppression of IL-6 biological activities by activin A and implications for inflammatory arthropathies. Yu EW Dolter KE, Shao LE Yu J, Clin Exp Immunol 1998 112 126 132 10.1046/j.1365-2249.1998.00522.x 9566800 (Pubitemid 28157109)
59. Activin A: a novel player and inflammatory marker in inflammatory bowel disease? Hubner G Brauchle M, Gregor M Werner S, Lab Invest 1997 77 311 318 9354766 (Pubitemid 27465593)
60. Potent induction of activin A secretion from monocytes and bone marrow stromal fibroblasts by cognate interaction with activated T cells. Abe M Shintani Y, Eto Y Harada K, Kosaka M Matsumoto T, J Leukoc Biol 2002 72 347 352 12149426
61. Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production. Robson NC Phillips DJ McAlpine T Shin A, Svobodova S Toy T, Pillay V Kirkpatrick N, Zanker D Wilson K, Helling I Wei H, Chen W Cebon J, Maraskovsky E, Blood 2008 111 2733 2743 10.1182/blood-2007-03-080994 18156495
62. Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. Greco SJ Liu K, Rameshwar P, Stem Cells 2007 25 3143 3154 10.1634/stemcells.2007-0351 17761754 (Pubitemid 350294440)