The Global Economic and Health Burden of Human Hookworm Infection

PLoS Neglected Tropical Diseases

Volumn 10, Issue 9, 2016, Pages

  Bartsch, Sarah M ^a   Hotez, Peter J ^b,c   Asti, Lindsey ^a   Zapf, Kristina M ^a   Bottazzi, Maria Elena ^b,c   Diemert, David J ^c,d   Lee, Bruce Y ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c Human Hookworm Vaccine Initiative   (United States)

^d GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ANEMIA; ARTICLE; CHILD; COGNITIVE DEFECT; DISEASE CONTROL; DISEASE SIMULATION; GROSS NATIONAL INCOME; HEALTH CARE COST; HOOKWORM INFECTION; HUMAN; INFANT; NEWBORN; NONHUMAN; PARASITE LOAD; PRODUCTIVITY; PUBLIC HEALTH; QUALITY ADJUSTED LIFE YEAR; TROPICAL DISEASE; COMPLICATION; COST OF ILLNESS; ECONOMICS; GLOBAL HEALTH; HOOKWORM INFECTIONS;

ANEMIA; COST OF ILLNESS; GLOBAL HEALTH; HEALTH CARE COSTS; HOOKWORM INFECTIONS; HUMANS; QUALITY-ADJUSTED LIFE YEARS;

EID: 84991769750     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0004922     Document Type: Article

References (51)

1. Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S, Hookworm Infection. New England Journal of Medicine. 2004;351:799–807. 15317893
2. Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006;367(9521):1521–32. doi: 10.1016/S0140-6736(06)68653-416679166.
3. Smith JL, Brooker S, Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review. Trop Med Int Health. 2010;15(7):776–95. doi: 10.1111/j.1365-3156.2010.02542.x20500563; PubMed Central PMCID: PMCPMC2916221.
4. Adegnika AA, Zinsou JF, Issifou S, Ateba-Ngoa U, Kassa RF, Feugap EN, et al. Randomized, controlled, assessor-blind clinical trial to assess the efficacy of single- versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris trichiura, and hookworm infection. Antimicrob Agents Chemother. 2014;58(5):2535–40. doi: 10.1128/AAC.01317-1324550339; PubMed Central PMCID: PMCPMC3993258.
5. Soukhathammavong PA, Sayasone S, Phongluxa K, Xayaseng V, Utzinger J, Vounatsou P, et al. Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR. PLoS Negl Trop Dis. 2012;6(1):e1417. doi: 10.1371/journal.pntd.000141722235353; PubMed Central PMCID: PMCPMC3250499.
6. Global Burden of Disease Study 2013 CollaboratorsGlobal, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800. doi: 10.1016/S0140-6736(15)60692-426063472; PubMed Central PMCID: PMCPMC4561509.
7. Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J, Helminth infections: the great neglected tropical diseases. J Clin Invest. 2008;118(4):1311–21. Epub 2008/04/03. doi: 10.1172/JCI3426118382743; PubMed Central PMCID: PMC2276811.
8. Knopp S, Mohammed KA, Rollinson D, Stothard JR, Khamis IS, Utzinger J, et al. Changing patterns of soil-transmitted helminthiases in Zanzibar in the context of national helminth control programs. Am J Trop Med Hyg. 2009;81(6):1071–8. Epub 2009/12/10. 81/6/1071 [pii] doi: 10.4269/ajtmh.2009.09–037719996439.
9. Pullan RL, Brooker SJ, The global limits and population at risk of soil-transmitted helmith infections in 2010. Parasites & Vectors. 2012;5:81.
10. Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A, Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol. 2010;8(11):814–26. Epub 2010/10/16. nrmicro2438 [pii] doi: 10.1038/nrmicro243820948553.
11. Mwangi TW, Bethony JM, Brooker S, Malaria and helminth interactions in humans: an epidemiological viewpoint. Ann Trop Med Parasitol. 2006;100(7):551–70. doi: 10.1179/136485906X11846816989681; PubMed Central PMCID: PMCPMC1858631.
12. Anderson RM, May RM, Infectious Diseases of Humans: Dynamics and Control: Oxford University Press; 1991.
13. Bradley M, Chandiwana SK, Bundy DA, Medley GF, The epidemiology and population biology of Necator americanus infection in a rural community in Zimbabwe. Trans R Soc Trop Med Hyg. 1992;86(1):73–6. Epub 1992/01/01. 1566314.
14. Lwambo NJS, Bundy DA, Medley GF, A new approach to morbidity risk assessment in hookworm endemic communities. Epidemiol Infect. 1992;108:469–81. 1601081
15. Sabatelli L, Ghani AC, Rodrigues LC, Hotez PJ, Brooker S, Modelling heterogeneity and the impact of chemotherapy and vaccination against human hookworm. Journal of the Royal Society Interface. 2008;5:1329–41.
16. Stoltzfus RJ, Dreyfuss ML, Chwaya HM, Albonico M, Hookworm control as a strategy to prevent iron deficiency. Nutr Rev. 1997;55(6):223–32. Epub 1997/06/01. 9279058.
17. Stoltzfus RJ, Chwaya HM, Tielsch JM, Schulze KJ, Albonico M, Savioli L, Epidemiology of iron deficiency anemia in Zanzibari schoolchildren: the importance of hookworms. American Journal of Clinical Nutrition. 1997;65:153–9. 8988928
18. Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, et al. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg. 2007;101(2):146–54. Epub 2006/10/10. S0035-9203(06)00236-7 [pii] doi: 10.1016/j.trstmh.2006.05.01217027054.
19. Koukounari A, Estambale BB, Njagi JK, Cundill B, Ajanga A, Crudder C, et al. Relationships between anaemia and parasitic infections in Kenyan schoolchildren: a Bayesian hierarchical modelling approach. Int J Parasitol. 2008;38(14):1663–71. Epub 2008/07/16. S0020-7519(08)00222-1 [pii] doi: 10.1016/j.ijpara.2008.05.01318621051; PubMed Central PMCID: PMC2649416.
20. Ngui R, Lim YAL, Kin LC, Cheun CS, Jaffar S, Association between anaemia, iron deficiency anaemia, neglected parasitici infections and socioeconomic factors in rural children of West Malaysia. PLoS Neglected Tropical Diseases. 2012;6(3):e1550. doi: 10.1371/journal.pntd.000155022413027
21. Stephenson LS, Latham MC, Kurz KM, Kinoti SN, Oduori ML, Crompton DWT, Relationships of Shistosoma hematobium, hookworm and malarial infections and metrifonate treatment to hemoglobin level in Kenyan school children. American Journal of Tropical Medicine and Hygiene. 1985;34(3):519–28. 4003667
22. Lenk EJ, Redekop WK, Luyendijk M, Rijnsburger AJ, Severens JL, Productivity loss related to neglected tropical diseases eligible for preventive chemotherapy: a systematic literature review. PLoS Negl Trop Dis. 2016;10(2):e0004397. doi: 10.1371/journal.pntd.000439726890487
23. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System. Geneva: 2011 Contract No.: (WHO/NMH/NHD/MNM/11.1).
24. World Health Organization, Centers for Disease Control and PreventionWorldwide prevalence of anaemia 1993–2005: WHO Global database on anaemia. Geneva, Switerzland: World Health Organization, 2008.
25. Shastry GK, Weil DN, How much of cross-country income variation is explained by health?Journal of the European Economic Association. 2003;1(2/3):387–96.
26. Alcazar L. The economic impact of anaemia in Peru. Lima, Peru: GRADE, Action Against Hunger, 2013.
27. Ross J, Horton S. Economic consequences of iron deficiency. Ottawa, ON Canada: Micronutrient Initiative, 1998.
28. United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: the 2015 Revision, DVD Edition 2015.
29. Pullan RL, Smith JL, Jasrasaria R, Brooker S, Global number of infection and disease burden of soil transmitted helminth infections in 2010. Parasites & Vectors. 2014;7:37.
30. Nguyen PH, Nguyen KC, Le MB, Nguyen TV, Ha KH, Bern C, et al. Risk factors for anemia in Vietnam. Southeast Asia Journal of Tropical Medicine and Public Health. 2006;37(6).
31. The World Bank. GNI per capita, Atlas method (current US$): The World Bank; 2015 [cited 2015 November]. Available from: http://data.worldbank.org/indicator/NY.GNP.PCAP.CD.
32. United Nations Statistics Division. UNdata: GNI per capita: United Nations; 2015 [cited 2015 March]. Available from: https://data.un.org/Data.aspx?d = SOWC&f = inID%3A94.
33. Bureau of Democracy Human Rights and Labor. Country Reports on Human Rights Practices for 2015: U.S. Department of State; 2015 [cited 2016 May 9]. Available from: http://www.state.gov/j/drl/rls/hrrpt/humanrightsreport/index.htm#wrapper.
34. Chan MS, Medley GF, Jamison D, Bundy DAP, The evaluation of potential global morbidity attributable to intestinal nematode infections. Parasitology. 1994;109:373–87. 7970892
35. Rheingans RD, Antil L, Dreibelbis R, Podewils LJ, Bresee JS, Parashar UD, Economic costs of rotavirus gastroenteritis and cost-effectiveness of vaccination in developing countries. J Infect Dis. 2009;200Suppl 1:S16–27. doi: 10.1086/60502619817595.
36. Grimwood K, Lambert SB, Milne RJ, Rotavirus infections and vaccines: burden of illness and potential impact of vaccination. Paediatr Drugs. 2010;12(4):235–56. doi: 10.2165/11537200-000000000-0000020593908.
37. Fonkwo PN, Pricing infectious disease. The economic and health implications of infectious disease. EMBO Reports. 2008;9(Suppl 1):S13–7. doi: 10.1038/embor.2008.11018578017
38. University of Pittsburgh Medical Center (UMPC). Infectious Disease Cost Calculator Baltimore, MD: UMPC; 2014 [cited 2015 July 2]. Available from: http://www.idcostcalc.org/contents/about/cost-of-ID.html.
39. Lee BY, Digital decision making: computer models and antibiotic prescribing in the twenty-first century. Clinical Infectious Diseases. 2008;46(8):1139–41. doi: 10.1086/52944118444847
40. Lee BY, Bartsch SM, Gorham KM, Economic and financial evaluation of neglected tropical diseases. Advances in Parasitology. 2015;87:329–417. doi: 10.1016/bs.apar.2015.01.00225765199
41. Brooker S, Bethony J, Hotez PJ, Human hookworm infection in the 21st century. Adv Parasitol. 2004;58:197–288. doi: 10.1016/S0065-308X(04)58004-115603764; PubMed Central PMCID: PMCPMC2268732.
42. Navitsky RC, Dreyfuss ML, Shrestha J, Khatry SK, Stoltzfus RJ, Albonico M, Ancylostoma duodenale is responsible for hookworm infections among pregnant women in the rural plains of Nepal. J Parasitol. 1998;84(3):647–51. 9645880.
43. Adenusi AA, Ogunyomi EOA, Relative prevalence of the human hookworm species, Nector americanus and Ancylostoma suodenale in an urban community in Ogun State, Nigeria. African Journal of Biotechnology. 2004;2(11):470–3.
44. Stoll NR, This wormy world. J Parasitol. 1947;33(1):1–18. 20284977.
45. Sakti H, Nokes C, Hertanto WS, Hendratno S, Hall A, Bundy DAP, et al. Evidence for an association between hookworm infection and cognitive function in Indonesian school children. Tropical Medicine and International Health. 1999;4(5):322–34. 10402967
46. Jardim-Botelho A, Raff S, de Avila Rodrigues R, Hoffman HJ, Diemert DJ, Correa-Oliveira R, et al. Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren. Tropical Medicine and International Health. 2008;13(8):994–1004. doi: 10.1111/j.1365-3156.2008.02103.x18627581
47. Bleakley H, Disease and Development: Evidence from Hookworm Eradication in the American South. Q J Econ. 2007;122(1):73–117. doi: 10.1162/qjec.121.1.7324146438; PubMed Central PMCID: PMCPMC3800113.
48. Baird S, Hicks JH, Kremer M, Miguel E. Worms at work: long-run impacts of child health gains 2011. Available from: http://www.cgdev.org/doc/events/KLPS-Labor_2011-05-16-Circulate.pdf.
49. World Health Organization. Global burden of disease 2004 update: disability weights for diseases and conditions. Geneva: WHO: 2004.
50. Salomon JA, Vos T, Hogan DR, Gagnon M, Naghavi M, Mokdad A, et al. Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2129–43. doi: 10.1016/S0140-6736(12)61680-823245605.
51. Gillespie S, Johnston JL, Expert consultation on anemia determinants and interventions. Ottawa, ON Canada: Micronutrient Initiative, 1998.