Extra- and Intraluminal Elastase Induce Morphologically Distinct Abdominal Aortic Aneurysms in Mice and Thus Represent Specific Subtypes of Human Disease

Journal of Vascular Research

Volumn 53, Issue 1-2, 2016, Pages 49-57

  Busch, Albert ^a   Holm, Amina ^a   Wagner, Nicole ^b   Ergün, Süleyman ^b   Rosenfeld, Mathias ^c   Otto, Christoph ^a   Baur, Johannes ^a   Kellersmann, Richard ^a   Lorenz, Udo ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b Institutes of Anatomy and Cell Biology   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Abdominal aortic aneurysms; Aneurysm mouse model; Angiogenesis; Elastase infusion; Endothelium; Inflammation

Indexed keywords

C REACTIVE PROTEIN; CD11B ANTIGEN; CD4 ANTIGEN; ELASTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; PANCREATIC ELASTASE;

ABDOMINAL AORTA ANEURYSM; ADVENTITIA; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; BLOOD CLOTTING; CELL POLARITY; CHRONIC INFLAMMATION; CLINICAL FEATURE; CONTROLLED STUDY; ELASTIC FIBER; ENDOTHELIUM CELL; GENE EXPRESSION; GLOBULIN BLOOD LEVEL; INFLAMMATORY CELL; LEUKOCYTE COUNT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TURNOVER TIME; VASCULAR REMODELING; VASCULITIS; ABDOMINAL AORTA; ABDOMINAL AORTIC ANEURYSM; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; ELASTIC TISSUE; GENETICS; HUMAN; INFLAMMATION; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHENOTYPE; PROTEIN DEGRADATION; TIME FACTOR; ULTRASTRUCTURE;

ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELASTIC TISSUE; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; MALE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC ELASTASE; PHENOTYPE; PROTEOLYSIS; TIME FACTORS;

EID: 84991738190     PISSN: 10181172     EISSN: 14230135     Source Type: Journal    
DOI: 10.1159/000447263     Document Type: Article

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