Differential Regulation of Aortic Growth in Male and Female Rodents Is Associated With AAA Development

Journal of Surgical Research

Volumn 155, Issue 2, 2009, Pages 330-338

  Cho, Brenda S ^a,b   Woodrum, Derek T ^b   Roelofs, Karen J ^b   Stanley, James C ^b   Henke, Peter K ^b   Upchurch Jr , Gilbert R ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Jobst Vascular Research Laboratories   (United States)

Author keywords

aneurysm; aorta; elastase, cytokine; estrogen; gender; hormone; rodent; testosterone

Indexed keywords

ELASTASE; ESTRADIOL; SEX HORMONE; TESTOSTERONE;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASTRATION; CELL COUNT; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; IMPLANTATION; MACROPHAGE; MALE; NONHUMAN; ORCHIECTOMY; OVARIECTOMY; OVARY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; STAINING; TESTIS;

ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ESTRADIOL; FEMALE; HUMANS; INFUSIONS, INTRA-ARTERIAL; MACROPHAGES; MALE; ORCHIECTOMY; OVARIECTOMY; PANCREATIC ELASTASE; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

EID: 67650932427     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.07.027     Document Type: Article

References (43)

1. Ailawadi G., Eliason J.L., and Upchurch Jr. G.R. Current concepts in the pathogenesis of abdominal aortic aneurysm. J Vasc Surg 38 (2003) 584
2. Vemuri C., Wainess R.M., Dimick J.B., et al. Effect of increasing patient age on complication rates following intact abdominal aortic aneurysm repair in the United States. J Surg Res 118 (2004) 26
3. Ailawadi G., Eliason J.L., Roelofs K.J., et al. Gender differences in experimental aortic aneurysm formation. Arterioscler Thromb Vasc Biol 24 (2004) 2116
4. Singh K., Bonaa K.H., Jacobsen B.K., et al. Prevalence of and risk factors for abdominal aortic aneurysms in a population-based study: The Tromso Study. Am J Epidemiol 154 (2001) 236
5. Bengtsson H., Sonesson B., and Bergqvist D. Incidence and prevalence of AAA. Ann NY Acad Sci 800 (1996) 1
6. Fischer G.M., and Swain M.L. Influence of contraceptive and other sex steroids on aortic collagen and elastin. Exp Mol Pathol 33 (1980) 15
7. Pirila E., Ramamurthy N., Maisi P., et al. Wound healing in ovariectomized rats: Effects of chemically modified tetracycline (CMT-8) and estrogen on matrix metalloproteinases -8, -13 and type I collagen expression. Curr Med Chem 8 (2001) 281
8. Mendelsohn M.E., and Karas R.H. Estrogen and the blood vessel wall. Curr Opin Cardiol 9 (1994) 619
9. Fischer-Dzoga K., Wissler R.W., and Vesselinovitch D. The effect of estradiol on the proliferation of rabbit aortic medial tissue culture cells induced by hyperlipemic serum. Exp Mol Pathol 39 (1983) 355
10. Foegh M.L., Asotra S., Howell M.H., et al. Estradiol inhibition of arterial neointimal hyperplasia after balloon injury. J Vasc Surg 19 (1994) 722
11. Farhat M.Y., Lavigne M.C., and Ramwell P.W. The vascular protective effects of estrogen. FASEB J 10 (1996) 615
12. La Vecchia C., Decarli A., Franceschi S., et al. Menstrual and reproductive factors and the risk of myocardial infarction in women under fifty-five years of age. Am J Obstet Gynecol 157 (1987) 1108
13. Squadrito F., Altavilla D., Campo G.M., et al. 17B-oestradiol reduces cardiac leukocyte accumulation in myocardial ischaemia reperfusion injury in rat. Eur J Pharmacol 335 (1997) 185
14. Fukuda K., Yao H., Ibayashi S., et al. Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats. Stroke 31 (2000) 155
15. Yang S.H., Perez E., Cutright J., et al. Testosterone increases neurotoxicity of glutamate in vitro and ischemia-reperfusion injury in an animal model. J Appl Physiol 92 (2002) 195
16. Ling S., Dai A., Williams M.R., et al. Testosterone (T) enhances apoptosis-related damage in human vascular endothelial cells. Endocrinology 143 (2002) 1119
17. Cavasin M.A., Sankey S.S., Yu A.L., et al. Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction. Am J Physiol Heart Circ Physiol 284 (2003) H1560
18. McCrohon J.A., Jessup W., Handelsman D.J., et al. Androgen exposure increases human monocyte adhesion to vascular endothelium and endothelial cell expression of vascular cell adhesion molecule-1. Circulation 99 (1999) 2317
19. Herman S.M., Robinson J.T., McCredie R.J., et al. Androgen deprivation is associated with enhanced endothelium-dependent dilatation in adult men. Arterioscler Thromb Vasc Biol 17 (1997) 2004
20. Henriques T.A., Huang J., D'Souza S.S., et al. Orchidectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E-deficient mice. Endocrinology 145 (2004) 3866
21. Anidjar S., Salzmann J.L., Gentric D., et al. Elastase-induced experimental aneurysms in rats. Circulation 82 (1990) 973
22. Brooks-Asplund E.M., Shoukas A.A., Kim S.Y., et al. Estrogen has opposing effects on vascular reactivity in obese, insulin-resistant male Zucker rats. J Appl Physiol 92 (2002) 2035
23. Gabrielsson B.G., Carmignac D.F., Flavell D.M., et al. Steroid regulation of growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids in the rat. Endocrinology 136 (1995) 209
24. Kwon J.H., Katz L.E., and Liljestrand H.M. Modeling binding equilibrium in a competitive estrogen receptor binding assay. Chemosphere 69 (2007) 1025
25. Huang C.H., and Sedlak D.L. Analysis of estrogenic hormones in municipal wastewater effluent and surface water using enzyme-linked immunosorbent assay and gas chromatography/tandem mass spectrometry. Environ Toxicol Chem 20 (2001) 133
26. Meinhardt A., Bacher M., Metz C., et al. Local regulation of macrophage subsets in the adult rat testis: Examination of the roles of the seminiferous tubules, testosterone, and macrophage-migration inhibitory factor. Biol Reprod 59 (1998) 371
27. Rosa F., Antequera R., Vasquez J., et al. Testosterone and nandrolone sensitization of brain anteroventral area of third ventricle to hypertonic NaCl-induced sympathetic response. Pharmacology 75 (2005) 5
28. Ishizuka T., Ito O., Omata K., et al. Role of androgens in the renal production of 20-hydroxyeicosatetraenoic acid in spontaneously hypertensive rats. Nippon Jinzo Gakkai Shi 46 (2004) 685
29. Yoshimura K., Aoki H., Ikeda Y., et al. Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase. Nature Medicine 11 (2005) 1330
30. Pan J.H., Lindholt J.S., Sukhova G.K., et al. Macrophage migration inhibitory factor is associated with aneurysmal expansion. J Vasc Surg 37 (2003) 628
31. Curci J.A., Lee J.K., and Thompson R.W. Pathogenesis of abdominal aortic aneurysm in current therapy. In: Ernst C.B., and Stanley J.C. (Eds). Vascular Surgery (2001), Elsevier, Philadelphia, PA 199-206
32. Pyo R., Lee J.K., Shipley J.M., et al. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. J Clin Invest 105 (2000) 1641
33. Longo G.M., Xiong W., Greiner T.C., et al. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 110 (2002) 625
34. Brouchet L., Krust A., Dupont S., et al. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-β. Circulation 103 (2001) 423
35. Pare G., Krust A., Karas R.H., et al. Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circ Res 90 (2002) 1087
36. Hishikawa K., Nakaki T., Marumo T., et al. Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells. FEBS Lett 360 (1995) 291
37. Angele M.K., Knoferl M.W., Schwach M.G., et al. Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage. Am J Physiol 277 (1999) C35
38. Angele M.K., Schwach M.G., Ayala A., et al. Effect of gender and sex hormones on immune responses following shock. Shock 14 (2000) 81
39. Knoferl M.W., Jarrar D., Angele M.K., et al. 17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage. Am J Physiol Cell Physiol 281 (2001) C1131
40. Park K.M., Kim J.I., Ahn Y.K., et al. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem 279 (2004) 52282
41. Sun X.Y., Donald S.P., and Phang J.M. Testosterone and prostrate specific antigen stimulate generation of reactive oxygen species in prostate cancer cells. Carcinogenesis 22 (2001) 1775
42. McCormick M.L., Gavrila D., and Weintraub N.L. Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms. ATVB 27 (2007) 461
43. Sinha I., Cho B.S., Roelofs K.J., et al. Female gender attenuates cytokine and chemokine expression and leukocyte recruitment in experimental rodent abdominal aortic aneurysms. Ann NY Acad Sci 1085 (2006) 367