Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for antidepressant effectiveness

Journal of Affective Disorders

Volumn 208, Issue , 2017, Pages 22-32

  Macedo, Danielle ^a   Filho, Adriano José Maia Chaves ^a   Soares de Sousa, Caren Nádia ^a   Quevedo, João ^b,c,d   Barichello, Tatiana ^b,c,d   Júnior, Hélio Vitoriano Nobre ^a   Freitas de Lucena, David ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

Author keywords

Antidepressants; Antimicrobials; Depression; Dysbiosis; Gut microbiota

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; ANTIINFECTIVE AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; CORTICOTROPIN; CYCLOOXYGENASE 2; ESCITALOPRAM; FLUOXETINE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; IPRONIAZID; ISOCARBOXAZID; MOCLOBEMIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PAROXETINE; PHENELZINE; PROSTAGLANDIN E2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SEROTONIN 1A RECEPTOR; SERTRALINE; TOLL LIKE RECEPTOR 4; TRANYLCYPROMINE; TUMOR NECROSIS FACTOR; UNINDEXED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1;

ANTIBIOTIC RESISTANCE; BACTERIAL COLONIZATION; BACTERIUM ADHERENCE; BACTERIUM IDENTIFICATION; BRAIN FUNCTION; CLINICAL EFFECTIVENESS; COMORBIDITY; DISEASE ASSOCIATION; DRUG STRUCTURE; DYSBIOSIS; EARLY LIFE STRESS; HORMONE RELEASE; HUMAN; INTESTINE FLORA; INTESTINE MUCOSA PERMEABILITY; MAJOR DEPRESSION; MICROBIAL DIVERSITY; NEUROTRANSMISSION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SYSTEMATIC REVIEW; DRUG EFFECTS; MICROBIOLOGY;

ANTI-INFECTIVE AGENTS; ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER, MAJOR; DYSBIOSIS; GASTROINTESTINAL MICROBIOME; HUMANS;

EID: 84991696768     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2016.09.012     Document Type: Review

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