Multiplexed molecular imaging of biomarker-targeted SERS nanoparticles on fresh tissue specimens with channel-compressed spectrometry

PLoS ONE

Volumn 11, Issue 9, 2016, Pages

  Kang, Soyoung ^a   Wang, Yu ^a   Reder, Nicholas P ^b   Liu, Jonathan T C ^a  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CONTROLLED STUDY; EX VIVO STUDY; HUMAN; HUMAN TISSUE; LIMIT OF DETECTION; MALE; MOLECULAR IMAGING; MOUSE; NANOANALYSIS; NONHUMAN; RAMAN SPECTROMETRY; RAT; SENSITIVITY ANALYSIS; TUMOR XENOGRAFT;

EID: 84991665788     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0163473     Document Type: Article

References (38)

1. DeSantis CE, Lin CC, Mariotto AB, Siegel RL, Stein KD, Kramer JL, et al. Cancer Treatment and Survivorship Statistics, 2014. CA: A Cancer Journal for Clinicians. 2014; 64(4):252-271. Available from: http://onlinelibrary.wiley.com/doi/10.3322/caac.21235/abstract. doi: 10.3322/caac.21235 PMID: 24890451
2. Sanai N, Berger MS. Glioma extent of resection and its impact on patient outcome. Neurosurgery. 2008; 62(4):753-766. Available from: http://journals.lww.com/neurosurgery/Abstract/2008/04000/Glioma-Extent-of-Resection-and-Its-Impact-on.10.aspx. doi: 10.1227/01.neu.0000318159.21731.cf PMID: 18496181
3. Regimbeau JM, Kianmanesh R, Farges O, Dondero F, Sauvanet A, Belghiti J. Extent of liver resection influences the outcome in patients with cirrhosis and small hepatocellular carcinoma. Surgery. 2002; 131(3):311-317. Available from: http://www.sciencedirect.com/science/article/pii/S0039606002154316. doi: 10.1067/msy.2002.121892 PMID: 11894036
4. Houssami N, Macaskill P, Luke Marinovich M, Morrow M. The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: A meta-analysis. Annals of Surgical Oncology. 2014; 21(3):717-730. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24473640. doi: 10.1245/s10434-014-3480-5 PMID: 24473640
5. Khalifeh A, Kaouk JH, Bhayani S, Rogers C, Stifelman M, Tanagho YS, et al. Positive surgical margins in robot-assisted partial nephrectomy: A multi-institutional analysis of oncologic outcomes (Leave no tumor behind). Journal of Urology. 2013; 190(5):1674-1679. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23764077. doi: 10.1016/j.juro.2013.05.110 PMID: 23764077
6. Hinni ML, Ferlito A, Brandwein-Gensler MS, Takes RP, Silver CE, Westra WH, et al. Surgical margins in head and neck cancer: A contemporary review. Head Neck. 2013; 35(9):1362-70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22941934. doi: 10.1002/hed.23110 PMID: 22941934
7. Pleijhuis RG, Graafland M, de Vries J, Bart J, de Jong JS, van Dam GM. Obtaining adequate surgical margins in breast-conserving therapy for patients with early-stage breast cancer: current modalities and future directions. Annals of Surgical Oncology. 2009; 16(10):2717-2730. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19609829. doi: 10.1245/s10434-009-0609-z PMID: 19609829
8. Kouzminova NB, Aggarwal S, Aggarwal A, Allo MD, Lin AY. Impact of initial surgical margins and residual cancer upon re-excision on outcome of patients with localized breast cancer. American Journal of Surgery. 2009; 198(6):771-780. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19969128. doi: 10.1016/j.amjsurg.2009.05.027 PMID: 19969128
9. Menes TS, Tartter PI, Bleiweiss I, Godbold JH, Estabrook A, Smith SR. The consequence of multiple re-excisions to obtain clear lumpectomy margins in breast cancer patients. Annals of surgical oncology. 2005; 12(11):881-885. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16195834. doi: 10.1245/ASO.2005.03.021 PMID: 16195834
10. Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJH, Frangioni JV. Image-guided cancer surgery using near-infrared fluorescence. Nature reviews Clinical oncology. 2013; 10(9):507-18. Available from: http://www.nature.com/nrclinonc/journal/v10/n9/full/nrclinonc.2013.123.html. doi: 10.1038/nrclinonc.2013.123 PMID: 23881033
11. van Dam GM, Themelis G, Crane LMa, Harlaar NJ, Pleijhuis RG, Kelder W, et al. Intraoperative tumorspecific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nature medicine. 2011; 17(10):1315-9. Available from: http://www.nature.com/nm/journal/v17/n10/full/nm.2472.html. doi: 10.1038/nm.2472 PMID: 21926976
12. Yang DJ, Kim EE, Inoue T. Targeted molecular imaging in oncology. Annals of Nuclear Medicine. 2006; 20(1):1-11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16485568. doi: 10.1007/BF02985584 PMID: 16485568
13. Gerlinger M, Rowan AJ, Stuart H, James L, David E, Eva G, et al. Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. New England Journal of Medicine. 2012; 366(10):883-892. Available from: http://www.nejm.org/doi/full/10.1056/NEJMoa1113205. doi: 10.1056/NEJMoa1113205 PMID: 22397650
14. Fidler IJ. Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis. Cancer research. 1978; 38(September):2651-2660. Available from: http://www.ncbi.nlm.nih.gov/pubmed/354778. PMID: 354778
15. Longo D. Tumor heterogeneity and personalized medicine. N Engl J Med. 2012; 366:956-957. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22397658. doi: 10.1056/NEJMe1200656 PMID: 22397658
16. Mohs AM, Mancini MC, Singhal S, Provenzale JM, Leyland-Jones B, Wang MD, et al. Hand-held spectroscopic device for in vivo and intraoperative tumor detection: Contrast enhancement, detection sensitivity, and tissue penetration. Analytical Chemistry. 2010; 82(21):9058-9065. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20925393. doi: 10.1021/ac102058k PMID: 20925393
17. Mulvaney SP, Musick MD, Keating CD, Natan MJ. Glass-coated, analyte-tagged nanoparticles: a new tagging system based on detection with surface-enhanced Raman scattering. Langmuir. 2003; 19(11):47834790. Available from: http://pubs.acs.org/doi/abs/10.1021/la026706j. doi: 10.1021/la026706j
18. Zavaleta CL, Garai E, Liu JTC, Sensarn S, Mandella MJ, Van de Sompel D, et al. A Raman-based endoscopic strategy for multiplexed molecular imaging. Proceedings of the National Academy of Sciences of the United States of America. 2013jun; 110(25):E2288-97. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23703909. doi: 10.1073/pnas.1211309110 PMID: 23703909
19. Zavaleta CL, Smith BR, Walton I, Doering W, Davis G, Shojaei B, et al. Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 2009aug; 106(32):13511-6. Available from: http://www.pnas.org/content/106/32/13511.abstract. doi: 10.1073/pnas.0813327106 PMID: 19666578
20. Leigh SY, Som M, Liu JTC. Method for Assessing the Reliability of Molecular Diagnostics Based on Multiplexed SERS-Coded Nanoparticles. PLoS ONE. 2013; 8(4). Available from: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062084. doi: 10.1371/journal.pone.0062084 PMID: 23620806
21. Garai E, Sensarn S, Zavaleta CL, Van de Sompel D, Loewke NO, Mandella MJ, et al. High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device. Journal of biomedical optics. 2013sep; 18(9):096008. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24008818. doi: 10.1117/1.JBO.18.9.096008 PMID: 24008818
22. Liu JTC, Helms MW, Mandella MJ, Crawford JM, Kino GS, Contag CH. Quantifying cell-surface biomarker expression in thick tissues with ratiometric three-dimensional microscopy. Biophysical Journal.2009; 96(6):2405-2414. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19289065. doi: 10.1016/j.bpj.2008.12.3908 PMID: 19289065
23. Wang Y, Kang S, Khan A, Ruttner G, Leigh SY, Murray M, et al. Quantitative molecular phenotyping with topically applied SERS nanoparticles for intraoperative guidance of breast cancer lumpectomy. Scientific Reports. 2016; 6(February):21242. Available from: http://www.nature.com/articles/srep21242. doi: 10.1038/srep21242 PMID: 26878888
24. Wang YW, Khan A, Som M, Wang D, Chen Y, Leigh SY, et al. Rapid ratiometric biomarker detection with topically applied SERS nanoparticles. Technology. 2014jun; 2(2):118-132. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25045721. doi: 10.1142/S2339547814500125 PMID: 25045721
25. Wang YW, Khan A, Leigh SY, Wang D, Chen Y, Meza D, et al. Comprehensive spectral endoscopy of topically applied SERS nanoparticles in the rat esophagus. Biomedical optics express. 2014sep; 5(9):2883-95. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25401005. doi: 10.1364/BOE.5.002883 PMID: 25401005
26. Sinha L, Wang Y, Yang C, Khan A, Brankov JG, Liu JTC, et al. Quantification of the binding potential of cell-surface receptors in fresh excised specimens via dual-probe modeling of SERS nanoparticles. Scientific Reports. 2014; 5:1-8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25716578. doi: 10.1038/srep08582 PMID: 25716578
27. Tichauer KM, Samkoe KS, Sexton KJ, Hextrum SK, Yang HH, Klubben WS, et al. In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging. Mol Imaging Biol. 2012; 14(5):584-592. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22203241. doi: 10.1007/s11307-011-0534-y PMID: 22203241
28. Tichauer KM, Samkoe KS, Gunn JR, Kanick SC, Hoopes PJ, Barth RJ, et al. Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging. Nature Medicine. 2014oct; 20(11). Available from: http://www.ncbi.nlm.nih.gov/pubmed/25344739. doi: 10.1038/nm.3732 PMID: 25344739
29. Tichauer KM, Samkoe KS, Sexton KJ, Gunn JR, Hasan T, Pogue BW. Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging. Journal of biomedical optics. 2012jun; 17(6):1-10. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22734757. doi: 10.1117/1.JBO.17.6.066001 PMID: 22734757
30. Sabel MS, Jorns JM, Wu A, Myers J, Newman LA, Breslin TM. Development of an intraoperative pathology consultation service at a free-standing ambulatory surgical center: Clinical and economic impact for patients undergoing breast cancer surgery. American Journal of Surgery. 2012; 204(1):66-77. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22178485. doi: 10.1016/j.amjsurg.2011.07.016 PMID: 22178485
31. Wang Y, Kang S, Doerksen JD, Glaser AK, Liu JTC. Surgical Guidance via Multiplexed Molecular Imaging of Fresh Tissues Labeled With. IEEE Journal of quantum electronics. 2016; 22(4). Available from: http://ieeexplore.ieee.org/xpls/abs-all.jsp?arnumber=7350220. doi: 10.1109/JSTQE.2015.2507358 PMID: 27524875
32. Wang YW, Kang S, Khan A, Bao PQ, Liu JTC. In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles. Biomedical optics express. 2015; 6(10):3714-23. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605032/. doi: 10.1364/BOE.6.003714 PMID: 26504623
33. Wang Y, Yan B, Chen L. SERS tags: novel optical nanoprobes for bioanalysis. Chemical reviews. 2013mar; 113(3):1391-428. Available from: http://pubs.acs.org/doi/abs/10.1021/cr300120g. doi: 10.1021/cr300120g PMID: 23273312
34. Siegel R, Miller K, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2015; 65(1):29. Available from: http://onlinelibrary.wiley.com/doi/10.3322/caac.21254/pdf. doi: 10.3322/caac.21254 PMID: 25559415
35. McVeigh PZ, Mallia RJ, Veilleux I, Wilson BC. Widefield quantitative multiplex surface enhanced Raman scattering imaging in vivo. Journal of biomedical optics. 2013; 18(4):046011. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23591913. doi: 10.1117/1.JBO.18.4.046011 PMID: 23591913
36. Andor. Newton CCD; 2009. Available from: http://www.andor.com/scientific-cameras/newton-ccd-and-emccd-cameras/newton-920.
37. Mather L. Linear array PMT modules by Hamamatsu; 2011. Available from: http://www.bioopticsworld.com/articles/2011/09/linear-array-pmt-modules-by-hamamatsu.html.
38. Sensor F. First Sensor APD Array Data Sheet; 2002. Available from: http://www.first-sensor.com/en/products/optical-sensors/detectors/avalanche-photodiode-arrays-apd-arrays/.