In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles

Biomedical Optics Express

Volumn 6, Issue 10, 2015, Pages 3714-3723

  Wang, Yu Winston ^a   Kang, Soyoung ^a   Khan, Altaz ^b   Bao, Philip Q ^c   Liu, Jonathan T C ^a  

^a University of Washington   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Stony Brook Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; CELL MEMBRANES; DATA VISUALIZATION; ENDOSCOPY; MOLECULAR IMAGING; MULTIPLEXING; NANOPARTICLES; RAMAN SCATTERING; RATS; SURFACE SCATTERING; TUMORS;

ENDOSCOPIC IMAGING; IMMUNOHISTOCHEMISTRY; MULTIPLEXED DETECTION; NON-SPECIFIC BINDING; RATIOMETRIC ANALYSIS; SPECTRAL ENDOSCOPES; SURFACE ENHANCED RAMAN SCATTERING (SERS); TOPICAL APPLICATION;

DISEASES;

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; ENDOSCOPY; ESOPHAGUS CANCER; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOLECULAR IMAGING; NONHUMAN; RAMAN SPECTROMETRY; RAT; TUMOR XENOGRAFT; VALIDATION PROCESS;

EID: 84948746145     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.6.003714     Document Type: Article

References (41)

1. D. M. Parkin, F. I. Bray, and S. S. Devesa, Cancer burden in the year 2000. The global picture, Eur. J. Cancer 37(Suppl 8), S4-S66 (2001).
2. R. F. Souza, Molecular and biologic basis of upper gastrointestinal malignancy-esophageal carcinoma, Surg. Oncol. Clin. N. Am. 11(2), 257-272 (2002).
3. J. C. Layke and P. P. Lopez, Esophageal cancer: a review and update, Am. Fam. Physician 73(12), 2187-2194 (2006).
4. A. P. Polednak, Trends in survival for both histologic types of esophageal cancer in US surveillance, epidemiology and end results areas, Int. J. Cancer 105(1), 98-100 (2003).
5. M. Younes, D. E. Henson, A. Ertan, and C. C. Miller, Incidence and survival trends of esophageal carcinoma in the United States: racial and gender differences by histological type, Scand. J. Gastroenterol. 37(12), 1359-1365 (2002).
6. M. B. Sturm, B. P. Joshi, S. Lu, C. Piraka, S. Khondee, B. J. Elmunzer, R. S. Kwon, D. G. Beer, H. D. Appelman, D. K. Turgeon, and T. D. Wang, Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results, Sci. Transl. Med. 5(184), 184-61 (2013).
7. E. L. Bird-Lieberman, A. A. Neves, P. Lao-Sirieix, M. O'Donovan, M. Novelli, L. B. Lovat, W. S. Eng, L. K. Mahal, K. M. Brindle, and R. C. Fitzgerald, Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus, Nat. Med. 18(2), 315-321 (2012).
8. T. I. Samoylova, N. E. Morrison, L. P. Globa, and N. R. Cox, Peptide phage display: opportunities for development of personalized anti-cancer strategies, Anticancer. Agents Med. Chem. 6(1), 9-17 (2006).
9. R. Weissleder, B. D. Ross, A. Rehemtulla, and S. S. Gambhir, Molecular Imaging: Principles and Practice (People's Medical Publishing House, 2010).
10. A. Hellebust and R. Richards-Kortum, Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics, Nanomedicine (Lond.) 7(3), 429-445 (2012).
11. Q. T. Nguyen and R. Y. Tsien, Fluorescence-guided surgery with live molecular navigation-a new cutting edge, Nat. Rev. Cancer 13(9), 653-662 (2013).
12. Y. Wang, B. Yan, and L. Chen, SERS Tags: Novel Optical Nanoprobes for Bioanalysis, Chem. Rev. 113(3), 1391-1428 (2013).
13. C. L. Zavaleta, B. R. Smith, I. Walton, W. Doering, G. Davis, B. Shojaei, M. J. Natan, and S. S. Gambhir, Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy, Proc. Natl. Acad. Sci. U. S. A. 106(32), 13511-13516 (2009).
14. C. L. Zavaleta, E. Garai, J. T. C. Liu, S. Sensarn, M. J. Mandella, D. Van de Sompel, S. Friedland, J. Van Dam, C. H. Contag, and S. S. Gambhir, A Raman-based endoscopic strategy for multiplexed molecular imaging, Proc. Natl. Acad. Sci. U. S. A. 110(25), E2288-E2297 (2013).
15. S. E. Bohndiek, A. Wagadarikar, C. L. Zavaleta, D. Van de Sompel, E. Garai, J. V. Jokerst, S. Yazdanfar, and S. S. Gambhir, A small animal Raman instrument for rapid, wide-area, spectroscopic imaging, Proc. Natl. Acad. Sci. U. S. A. 110(30), 12408-12413 (2013).
16. P. Z. McVeigh, R. J. Mallia, I. Veilleux, and B. C. Wilson, Widefield quantitative multiplex surface enhanced Raman scattering imaging in vivo, J. Biomed. Opt. 18(4), 046011 (2013).
17. E. Garai, S. Sensarn, C. L. Zavaleta, D. Van de Sompel, N. O. Loewke, M. J. Mandella, S. S. Gambhir, and C. H. Contag, High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device, J. Biomed. Opt. 18(9), 096008 (2013).
18. R. J. Mallia, P. Z. McVeigh, I. Veilleux, and B. C. Wilson, Filter-based method for background removal in high-sensitivity wide-field-surface-enhanced Raman scattering imaging in vivo, J. Biomed. Opt. 17(7), 0760171 (2012).
19. J. V. Jokerst, Z. Miao, C. Zavaleta, Z. Cheng, and S. S. Gambhir, Affibody-Functionalized Gold-Silica Nanoparticles for Raman Molecular Imaging of the Epidermal Growth Factor Receptor, Small 7(5), 625-633 (2011).
20. X. Wang, X. Qian, J. J. Beitler, Z. G. Chen, F. R. Khuri, M. M. Lewis, H. J. C. Shin, S. Nie, and D. M. Shin, Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles, Cancer Res. 71(5), 1526-1532 (2011).
21. S. Lee, H. Chon, S.-Y. Yoon, E. K. Lee, S.-I. Chang, D. W. Lim, and J. Choo, Fabrication of SERSfluorescence dual modal nanoprobes and application to multiplex cancer cell imaging, Nanoscale 4(1), 124-129 (2012).
22. L. Sun, K.-B. Sung, C. Dentinger, B. Lutz, L. Nguyen, J. Zhang, H. Qin, M. Yamakawa, M. Cao, Y. Lu, A. J. Chmura, J. Zhu, X. Su, A. A. Berlin, S. Chan, and B. Knudsen, Composite organic-inorganic nanoparticles as Raman labels for tissue analysis, Nano Lett. 7(2), 351-356 (2007).
23. X. Su, J. Zhang, L. Sun, T. W. Koo, S. Chan, N. Sundararajan, M. Yamakawa, and A. A. Berlin, Composite organic-inorganic nanoparticles (COINs) with chemically encoded optical signatures, Nano Lett. 5(1), 49-54 (2005).
24. Y. W. Wang, A. Khan, M. Som, D. Wang, Y. Chen, S. Y. Leigh, D. Meza, P. Z. McVeigh, B. C. Wilson, and J. T. C. Liu, Rapid ratiometric biomarker detection with topically applied SERS nanoparticles, Technology (Singap World Sci) 2(2), 118-132 (2014).
25. A. S. Thakor, R. Luong, R. Paulmurugan, F. I. Lin, P. Kempen, C. Zavaleta, P. Chu, T. F. Massoud, R. Sinclair, and S. S. Gambhir, The fate and toxicity of Raman-active silica-gold nanoparticles in mice, Sci. Transl. Med. 3(79), 79-33 (2011).
26. C. L. Zavaleta, K. B. Hartman, Z. Miao, M. L. James, P. Kempen, A. S. Thakor, C. H. Nielsen, R. Sinclair, Z. Cheng, and S. S. Gambhir, Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging, Small 7(15), 2232-2240 (2011).
27. Y. W. Wang, A. Khan, S. Y. Leigh, D. Wang, Y. Chen, D. Meza, and J. T. C. Liu, Comprehensive spectral endoscopy of topically applied SERS nanoparticles in the rat esophagus, Biomed. Opt. Express 5(9), 2883-2895 (2014).
28. K. M. Tichauer, K. S. Samkoe, K. J. Sexton, J. R. Gunn, T. Hasan, and B. W. Pogue, Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging, J. Biomed. Opt. 17(6), 066001 (2012).
29. J. T. C. Liu, M. W. Helms, M. J. Mandella, J. M. Crawford, G. S. Kino, and C. H. Contag, Quantifying Cell-Surface Biomarker Expression in Thick Tissues with Ratiometric Three-Dimensional Microscopy, Biophys. J. 96(6), 2405-2414 (2009).
30. K. M. Tichauer, K. S. Samkoe, K. J. Sexton, S. K. Hextrum, H. H. Yang, W. S. Klubben, J. R. Gunn, T. Hasan, and B. W. Pogue, In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging, Mol. Imaging Biol. 14(5), 584-592 (2012).
31. W. E. Doering, M. E. Piotti, M. J. Natan, and R. G. Freeman, SERS as a Foundation for Nanoscale, Optically Detected Biological Labels, Adv. Mater. 19(20), 3100-3108 (2007).
32. M. M. Moasser, A. Basso, S. D. Averbuch, and N. Rosen, The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells, Cancer Res. 61(19), 7184-7188 (2001).
33. N. Gaborit, C. Larbouret, J. Vallaghe, F. Peyrusson, C. Bascoul-Mollevi, E. Crapez, D. Azria, T. Chardès, M.-A. Poul, G. Mathis, H. Bazin, and A. Pèlegrin, Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies, J. Biol. Chem. 286(13), 11337-11345 (2011).
34. M. Schmidt, N. E. Hynes, B. Groner, and W. Wels, A bivalent single-chain antibody-toxin specific for ErbB-2 and the EGF receptor, Int. J. Cancer 65(4), 538-546 (1996).
35. W. Wels, R. Beerli, P. Hellmann, M. Schmidt, B. M. Marte, E. S. Kornilova, A. Hekele, J. Mendelsohn, B. Groner, and N. E. Hynes, EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins, Int. J. Cancer 60(1), 137-144 (1995).
36. B. Stea, R. Falsey, K. Kislin, J. Patel, H. Glanzberg, S. Carey, A. A. Ambrad, E. J. Meuillet, and J. D. Martinez, Time and dose-dependent radiosensitization of the glioblastoma multiforme U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa'), Cancer Lett. 202(1), 43-51 (2003).
37. A. A. Habib, S. J. Chun, B. G. Neel, and T. Vartanian, Increased Expression of Epidermal Growth Factor Receptor Induces Sequestration of Extracellular Signal-Related Kinases and Selective Attenuation of Specific Epidermal Growth Factor-Mediated Signal Transduction Pathways, Mol. Cancer Res. 1(3), 219-233 (2003).
38. S. Y. Leigh, M. Som, and J. T. C. Liu, Method for Assessing the Reliability of Molecular Diagnostics Based on Multiplexed SERS-Coded Nanoparticles, PLoS One 8(4), e62084 (2013).
39. B. D. Chithrani, A. A. Ghazani, and W. C. W. Chan, Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells, Nano Lett. 6(4), 662-668 (2006).
40. S. Keren, C. Zavaleta, Z. Cheng, A. de la Zerda, O. Gheysens, and S. S. Gambhir, Noninvasive molecular imaging of small living subjects using Raman spectroscopy, Proc. Natl. Acad. Sci. U. S. A. 105(15), 5844-5849 (2008).
41. E. Garai, S. Sensarn, C. L. Zavaleta, N. O. Loewke, S. Rogalla, M. J. Mandella, S. A. Felt, S. Friedland, J. T. C. Liu, S. S. Gambhir, and C. H. Contag, A Real-Time Clinical Endoscopic System for Intraluminal, Multiplexed Imaging of Surface-Enhanced Raman Scattering Nanoparticles, PLoS One 10(4), e0123185 (2015).